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The map label for this gene is pdxA

Identifier: 154246773

GI number: 154246773

Start: 3160792

End: 3161844

Strand: Reverse

Name: pdxA

Synonym: Xaut_2834

Alternate gene names: 154246773

Gene position: 3161844-3160792 (Counterclockwise)

Preceding gene: 154246774

Following gene: 154246772

Centisome position: 59.56

GC content: 73.88

Gene sequence:

>1053_bases
ATGGTCGCGCCCGCTCCCCTCGTCCTCTCCCTCGGTGATCCTGCCGGCATCGGCCCCGACATCACGCTCACGGCCTGGGC
GCAGCGCCGGGAGCTGGGCCTGCCCGCCTTCCTCGTCGCCGGCGATCCCGAAGCGCTCAAGGCCCGGGTCCGCCAGCTCG
GCCTCACCGTGCCGCTGGCCGAGACCGGTCCGGAAGACGCCGCCGGCCACTTCGCCGAGGCGCTGCCGGTGATGCCCGCC
GGTCCCGCCTCCACCGCCCTGCCCGGCGCGCCCGATGCCTCCAGCGCGCCCTGCGTGGTGGCAAGCCTTGAGGCGGCCCT
CGGCCTGGTCCAGGCCGGCCGCGCGGCGGCGCTGGTCACCAATCCGTTGGCGAAGTCGGTCATGTATGCGGGCGGCTTTC
CGTTTCCCGGCCACACCGAGTTCCTGGCCGCCCGCGCCGCGCGCCCGGGCCGACCCGCACCCCATCCGGTGATGATGATC
TGGTCGGAGCAACTCGCCGTGGTGCCGGCCACCATCCACCTGCCCTATGCGGACGTGCCCGGCCATCTCACCATCGACCT
CCTGGTGGAGACCGGCCGCATCGTCGCCGGCGACATGGCCCGGCGCTTCGGCCTCGCCCACCCCCGGCTGGTGTTCTGCG
GCCTCAACCCCCATGCGGGCGAGGAGGGCACCCTCGGCACCGAGGATGAGGCCATCGTGCGCCCGGCGGTCGAAGCCCTC
AAGCGCGAGGGCATCGACGCGCGGGGTCCCCTGCCCGCCGACACACTGTTCCACCCGCAGGCGCGGGCCGGCTACGACGT
GGCGGTGGGCATGTATCACGACCAGGTGCTGATCCCGGCCAAGACGCTGGCCTTCCACGACGGGGTGAATGTGACGCTGG
GCCTGCCCTTCATCCGCACCTCGCCCGATCACGGCACCGCCTTCGACATCGCGGGAACGGGCCGCGCCAACCCCTCAAGC
CTGGTGGCGGCGCTGCGGCTCGCCCGCCGCCTCGCGGATGCGGAAGCGCGGCTTGCCGCGCGCGAAGGCCACCGCGCGGC
GAGTGTAGCGTGA

Upstream 100 bases:

>100_bases
TTAGTATCCAACGGCCGGTTCCGGCGATTTTGCCGCGTGCCGCCGTTCAGCGCGTTTTCATGACGCAAAACCGGTTTCAA
CTTTTGCGGAAAACGCTGTG

Downstream 100 bases:

>100_bases
GCGCCCTCGACGACCTGCCGCCGCTGCGCGATGTCATCCGGCGGCACGGCCTCTCGGCGCAGAAGTCGCTGGGCCAGAAC
TTCCTTCTGGACCTCAACCT

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MVAPAPLVLSLGDPAGIGPDITLTAWAQRRELGLPAFLVAGDPEALKARVRQLGLTVPLAETGPEDAAGHFAEALPVMPA
GPASTALPGAPDASSAPCVVASLEAALGLVQAGRAAALVTNPLAKSVMYAGGFPFPGHTEFLAARAARPGRPAPHPVMMI
WSEQLAVVPATIHLPYADVPGHLTIDLLVETGRIVAGDMARRFGLAHPRLVFCGLNPHAGEEGTLGTEDEAIVRPAVEAL
KREGIDARGPLPADTLFHPQARAGYDVAVGMYHDQVLIPAKTLAFHDGVNVTLGLPFIRTSPDHGTAFDIAGTGRANPSS
LVAALRLARRLADAEARLAAREGHRAASVA

Sequences:

>Translated_350_residues
MVAPAPLVLSLGDPAGIGPDITLTAWAQRRELGLPAFLVAGDPEALKARVRQLGLTVPLAETGPEDAAGHFAEALPVMPA
GPASTALPGAPDASSAPCVVASLEAALGLVQAGRAAALVTNPLAKSVMYAGGFPFPGHTEFLAARAARPGRPAPHPVMMI
WSEQLAVVPATIHLPYADVPGHLTIDLLVETGRIVAGDMARRFGLAHPRLVFCGLNPHAGEEGTLGTEDEAIVRPAVEAL
KREGIDARGPLPADTLFHPQARAGYDVAVGMYHDQVLIPAKTLAFHDGVNVTLGLPFIRTSPDHGTAFDIAGTGRANPSS
LVAALRLARRLADAEARLAAREGHRAASVA
>Mature_350_residues
MVAPAPLVLSLGDPAGIGPDITLTAWAQRRELGLPAFLVAGDPEALKARVRQLGLTVPLAETGPEDAAGHFAEALPVMPA
GPASTALPGAPDASSAPCVVASLEAALGLVQAGRAAALVTNPLAKSVMYAGGFPFPGHTEFLAARAARPGRPAPHPVMMI
WSEQLAVVPATIHLPYADVPGHLTIDLLVETGRIVAGDMARRFGLAHPRLVFCGLNPHAGEEGTLGTEDEAIVRPAVEAL
KREGIDARGPLPADTLFHPQARAGYDVAVGMYHDQVLIPAKTLAFHDGVNVTLGLPFIRTSPDHGTAFDIAGTGRANPSS
LVAALRLARRLADAEARLAAREGHRAASVA

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family

Homologues:

Organism=Escherichia coli, GI1786237, Length=333, Percent_Identity=40.8408408408408, Blast_Score=216, Evalue=3e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXA_XANP2 (A7IJ81)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001417731.1
- ProteinModelPortal:   A7IJ81
- SMR:   A7IJ81
- STRING:   A7IJ81
- GeneID:   5423084
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_2834
- eggNOG:   COG1995
- HOGENOM:   HBG451136
- OMA:   LETAYQM
- ProtClustDB:   CLSK979874
- BioCyc:   XAUT78245:XAUT_2834-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00536
- InterPro:   IPR005255
- TIGRFAMs:   TIGR00557

Pfam domain/function: PF04166 PdxA

EC number: =1.1.1.262

Molecular weight: Translated: 36158; Mature: 36158

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: BINDING 138-138 BINDING 139-139 BINDING 281-281 BINDING 290-290 BINDING 299-299

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAPAPLVLSLGDPAGIGPDITLTAWAQRRELGLPAFLVAGDPEALKARVRQLGLTVPLA
CCCCCCEEEECCCCCCCCCCEEEEEEHHHHHCCCCEEEEECCHHHHHHHHHHHCCEEECC
ETGPEDAAGHFAEALPVMPAGPASTALPGAPDASSAPCVVASLEAALGLVQAGRAAALVT
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHH
NPLAKSVMYAGGFPFPGHTEFLAARAARPGRPAPHPVMMIWSEQLAVVPATIHLPYADVP
HHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCC
GHLTIDLLVETGRIVAGDMARRFGLAHPRLVFCGLNPHAGEEGTLGTEDEAIVRPAVEAL
CCEEEEEEEECCCEEEHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
KREGIDARGPLPADTLFHPQARAGYDVAVGMYHDQVLIPAKTLAFHDGVNVTLGLPFIRT
HHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEECHHHEEEECCCEEEEECCEEEE
SPDHGTAFDIAGTGRANPSSLVAALRLARRLADAEARLAAREGHRAASVA
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MVAPAPLVLSLGDPAGIGPDITLTAWAQRRELGLPAFLVAGDPEALKARVRQLGLTVPLA
CCCCCCEEEECCCCCCCCCCEEEEEEHHHHHCCCCEEEEECCHHHHHHHHHHHCCEEECC
ETGPEDAAGHFAEALPVMPAGPASTALPGAPDASSAPCVVASLEAALGLVQAGRAAALVT
CCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEHH
NPLAKSVMYAGGFPFPGHTEFLAARAARPGRPAPHPVMMIWSEQLAVVPATIHLPYADVP
HHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCC
GHLTIDLLVETGRIVAGDMARRFGLAHPRLVFCGLNPHAGEEGTLGTEDEAIVRPAVEAL
CCEEEEEEEECCCEEEHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHHHHH
KREGIDARGPLPADTLFHPQARAGYDVAVGMYHDQVLIPAKTLAFHDGVNVTLGLPFIRT
HHCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEEECHHHEEEECCCEEEEECCEEEE
SPDHGTAFDIAGTGRANPSSLVAALRLARRLADAEARLAAREGHRAASVA
CCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA