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The map label for this gene is lgrC [H]

Identifier: 154246724

GI number: 154246724

Start: 3084697

End: 3088809

Strand: Reverse

Name: lgrC [H]

Synonym: Xaut_2785

Alternate gene names: 154246724

Gene position: 3088809-3084697 (Counterclockwise)

Preceding gene: 154246725

Following gene: 154246715

Centisome position: 58.18

GC content: 71.82

Gene sequence:

>4113_bases
ATGGCCCCGTCGCCGCACGACCTCGCCCGCCGCTTCGCCCAGCTGGCACCGGAGAAGCGCCGCCACTTCCTGGACGCCCT
CGCGGCGGCAGGGGTGGACTTCCGCCTGCTGCCCATCCCGACGGCGCCCCGGCCGAACCGGCGCGCGCCCTTGTCCTTCG
CCCAGAATCGCATGTGGGTGGCGCAGCAGATGGGCGGCAATGGCGCCCTCAATACCATCGCCGGGGGCCTGCGCCTCGAC
GGCGCGCTCGATGGCGATGCCCTCGCCGCCGCCTTCTCCGACCTCTCGGCCCGCCACGAGGCCCTGCGCACCACCTTCGC
CCTGACCCCGGAGGGGGTGCCCGAGCAGGTGATCCACGAGACGGCGCCGATCGCTCTCGATCACGTGGACCTTTCCGGCG
CCGCCGATCCGGACGGGCGGCTGAAGGCCCTGTCCGACGCCGATGCCGCGCGGCCGTTCGATCTTCTCGCCGGACCGCTC
ACCCGTGCCACGCACGTGCGCCTTGCGCCAGACGCCCATGTGCTGCAGCTGACCCAGCATCACATCGTCTCCGATGGAGC
CTCCCTCTCCGTGCTGCTCCGGGACCTGATGGCGCTCTATGCCGCCCGGCGCGCCGGCACGTCCTCCCCGCTCACCCCTC
CGGCGCTGCACTATGCCGACTACGCCATCTGGCAGCGCAACTGGCTCGAGGCGGGCGAGATGGCGCGGCAGATCGAGGGC
TGGCGCACCCGCCTCGGCGACGGCGGCGCGCTCCTCGCCTTGCCCACGGACCGGCCGCGCCCGGCGACCCAAAGCCATCG
CGGCGGGCGCCACGCCGTCACCCTGGCTCCAGAGCTGGCCGCGCGCCTGCGCACTGTGACGCAAGAGGCCGGCGCCAGCA
CCGCCATGGGGCTGATGGCTGTGCTGCTGGCTTTGCTGTTCCGCCTCACCGGCGAGCGCGACCTGCGCCTCGGCATCCCC
GCCTCCAACCGCGACCGGCCGGAGACGCAGGACCTCGTCGGCCTGCTGGTGAACACGTTGGTGATCCGCGCCGAAGTCAC
CAGCACTACCAGTTACCGTGCTCTGCTCGATGCGGCGCGGGCCGCCCTGCTCGATGCCCAGACGCTTCAGGACGCGCCCT
TCGAGGAGGTGGTGGAGGCGCTCCAGCCTGAACGCAGCCTGGCCCGCAGCCCGCTGTTCCAGGTGATGCACAGCCATCTG
GTGGACGAGCGCCCCGCCCGCATGGCCGGCCTCACCCTCTCCCCCGTGGCGCGCGACACCGGGGCCATCGCCTTCGACCT
GGTGCTGGAGACCACCGAGCAGCCGGACGGCGTCATCATCGCCGCCTTCGGCTATGCCCGCGACCTGTTCCGGGCGGCGA
CCGTGGCGCGGATCGCGGAGCATTTCCTCGCCCTCGCTGAGCGCTGCCTCACCGTGCCCGATGCCCCCATCGGCGACTTC
CCGCTGGTGGACGAGGCGACCCTCGACCGGCTCTCCGCGCCATGGCCCGGCGACCTGCCCCTCGCCGATGGTCTGGTGCC
CCATCTGATCGCCGAGGCGGCGCAGCGGCGGCCCGATGCCCCCGCCGTGATCTGCGGCGACGAAACCCTGTCATTCGCCG
AACTGGAGCGAGCTGCGAACCGCATCGCCCATCATCTCCTGGGCCTCGGCGTCGGGGCGGAGACGCGGGTGGCGGTAGGC
CTACGGCGTGGGCCGGGGGCGGTGGCAGCCTTCCTCGGGGTGCTGAAGGCGGGCGCGGCCTTCGTGCCGTTCGATCCCGA
CCACCCGGCCGAGCGCATCGCTGATGTCGTGACGGATTCCGGCGCCACTTTCGCCGTTGTGAACGCGGACGGGCCGGCGC
TGCCGCAGGCCGTCACCGCCCTGGTGCCCGAGTGCCTCGACCTCGCAGCCCTTCCCGAGACCGCGCCGCAGGTGGTGATC
CACCCCGAGCAACTGGCCTATGTCATCTACACCTCCGGCTCCACCGGGCGGCCCAAGGGCGTGGGCGTGCCCCACGGCGC
CCTCGCCATGCATGTGCGCGCCACCGGGGCGCTCTATGGCACCGGCGAGGAGACGCGGGAGCTGCATTTCCTCTCCTTCG
CCTTCGATGGCGCTCACGAGCGCTGGATGGTGCCTTTGGCCTTCGGCGGCGCCATCGTGCTGCGGGACCAGGGCCTGTGG
AGCGCTGAGGAAACGCGGCACGCGCTGGCCCGCCACCGCGTCACTCACGCCGGCTTCCCGCCGGCCTATCTCACCCAGCT
CGCCGAATGGGTGGAGAGCGCAGGGGATCCGCCGCCGGTGCAGGTCTATTCCTTCGGCGGCGAGGCCATGCCCCGCGCCG
GCTTCGAGACGGTGAAGCGGGCGCTGCGCCCGCAGGTGCTCATCAATGGCTACGGCCCCACGGAGGCGGTGATCTCGCCC
ATGGCCTGGCGGGTTCCGGCCTCCGAGAGCTTCGACGGGCCATATGCCCCCATCGGTCGCGCCGTGGGCCAGCGCCGCGC
CTATGTGCTCGACGATGGCCTCCAGCCGGTGCCCATCGGTGTGGCGGGCGAGCTCTATCTCTCCGGGGAAGGGCTGGCGC
GCGGTTATCTCGGCCGCGCCGGCGCCACCGCCGAGCGCTTCCTGCCGGACCCCTTCGGCCCCTGCGGCGGGCGCATGTAC
CGCACCGGCGACCGGGTGCGGTGGCTGGCTGACGGAACCGTGGAATATCTCGGCCGCGCCGACCAGCAGATCAAGCTGCG
CGGCTTCCGCATCGAGCCCGGCGAGATCGAGGCCCAGCTGCGGCAGGAGGAGACGGTGCGTGAGGCGCTGGTGATGCTGC
GCACCGATGGCGCGGCCCCCCGGCTCGTCGCCTACGTCACCCCCGCCGAGGGCGCGGTGGCCGAGGAGGCAACCCTGCGC
GCCGCCCTACTGCGCCGCCTGCCGGACTATATGGTGCCCGGCCGCATTGTGGTTCTCGCCGCCTTTCCGGTGACCCCCAA
CGGCAAGCTGGACCGCGCCGCCTTGCCCGCCCCGCCTGAAACGCAGGATCTCGTCACCCCGCCCGAGGGCGAGACGCAGC
AGGCCATCGCCGCCATCTGGTGCGAGGTGCTGGGGCGCGCCAGCGTGGGCGCCAACCAGAACTTCTTCGACCTCGGCGGC
AATTCCCTCGCCGCGCTCCGGGTGCTGAACGCCCTCAGGACGCACTTCCCGGACAAGACCATCGGCGTGCCCCTGCTGTT
CAGCCACCAGGATGTGGCCAGCCTTGCCGCTGCCATCGACGCCGATGCGGTGGGCACGACCCAGGTGGTGCAGCTGAATC
CGCGCGGCAGCCGGCCCAGGCTCTACTGCTTCCCCGGCCTGATGGTGAACACCCGCGAATATGCCCCGCTGGTGCGCCGT
CTGGGACCGGACCAGCCGGTGACGGGCTTCGTGTGCTATTCCCTAACGGAGGAGCGCAAGAGCGTGGTGTCGGTGGAGGA
CATCGCCGCGCGCTACGCCGCCCACATCCGCACCGAATGCGCCGGTGGCAGCGCCACCCTGCTCGGCTGGTCGTGGGGCG
GGGTGCTGGCCTTCGAGGCCGCGCGGCTTCTGGCCGGCGAGGTGGACATCGGCTTCGTCGGCATGCTGGACGTGTGCAAT
CTCGACGTGAACTTCGCCGTGGGCCGGCTCGCCGACATCGCCTCCGCCGACCGCGCCCGCCTTGCCGGAGAGGTGGGGGC
ATGGCTCGACCGTGCCCCCATGCGGGCGGAATGGGAGAACCTGTTCGCGCGCATGGACGACACCCTGTTCACCCAGTTCC
TGCGCTACGTGGAGACCATCGGCGGCGACCTGCCCGCCGACGGTCCGGGCCTCGGCAGCCGGGAATACGAGCTCTTCACC
TTCATCGACAACACCCTGCTCTACCGGCGCTATTCCATGGCGCCGTTCGATGTGCCGGTGCGGGTATGGTTGGCGGAAAA
CTCGGTGGCGCGCGGGCTCGACCTCGTGGACTGGAGCCGCTATTCGCCCCGCGTGGACCAGGTGGAGGTGATCCCCGGCG
TCACCCATCGCGAGATCGTGGACAGCGCGCGCTTCCATGACAGCTTCGCCCGCAGCCTCGCCAAGGCGTGGGACGCACCC
AGCCGTGCGGCTTTGGCCGGGGCGGCGGAATGA

Upstream 100 bases:

>100_bases
CCACGGAGACGCGCGCCACCGGGGCCGCGCCCAGGCCGGCGCTCGGCGCAGATGCGCTGGCGCAGATGGATGCGCTGCTC
GGCGAACTGGAGGGATGAGC

Downstream 100 bases:

>100_bases
GGGTCGTGCCCGCGATCCGGCAGGCCCTGAACGGCCGAGCCGCAATCACGCCGCTGTGCCCGGCCTTGTGCCGGGCATCC
ACGCCTGCCCGCTGGAACAC

Product: amino acid adenylation domain-containing protein

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan adenylase; TrpA; Tryptophan activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent tryptophan/phenylalanine/tyrosine adenylase; Trp/Phe/TyrA; Tryptophan/phenylalanine/tyrosine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1370; Mature: 1369

Protein sequence:

>1370_residues
MAPSPHDLARRFAQLAPEKRRHFLDALAAAGVDFRLLPIPTAPRPNRRAPLSFAQNRMWVAQQMGGNGALNTIAGGLRLD
GALDGDALAAAFSDLSARHEALRTTFALTPEGVPEQVIHETAPIALDHVDLSGAADPDGRLKALSDADAARPFDLLAGPL
TRATHVRLAPDAHVLQLTQHHIVSDGASLSVLLRDLMALYAARRAGTSSPLTPPALHYADYAIWQRNWLEAGEMARQIEG
WRTRLGDGGALLALPTDRPRPATQSHRGGRHAVTLAPELAARLRTVTQEAGASTAMGLMAVLLALLFRLTGERDLRLGIP
ASNRDRPETQDLVGLLVNTLVIRAEVTSTTSYRALLDAARAALLDAQTLQDAPFEEVVEALQPERSLARSPLFQVMHSHL
VDERPARMAGLTLSPVARDTGAIAFDLVLETTEQPDGVIIAAFGYARDLFRAATVARIAEHFLALAERCLTVPDAPIGDF
PLVDEATLDRLSAPWPGDLPLADGLVPHLIAEAAQRRPDAPAVICGDETLSFAELERAANRIAHHLLGLGVGAETRVAVG
LRRGPGAVAAFLGVLKAGAAFVPFDPDHPAERIADVVTDSGATFAVVNADGPALPQAVTALVPECLDLAALPETAPQVVI
HPEQLAYVIYTSGSTGRPKGVGVPHGALAMHVRATGALYGTGEETRELHFLSFAFDGAHERWMVPLAFGGAIVLRDQGLW
SAEETRHALARHRVTHAGFPPAYLTQLAEWVESAGDPPPVQVYSFGGEAMPRAGFETVKRALRPQVLINGYGPTEAVISP
MAWRVPASESFDGPYAPIGRAVGQRRAYVLDDGLQPVPIGVAGELYLSGEGLARGYLGRAGATAERFLPDPFGPCGGRMY
RTGDRVRWLADGTVEYLGRADQQIKLRGFRIEPGEIEAQLRQEETVREALVMLRTDGAAPRLVAYVTPAEGAVAEEATLR
AALLRRLPDYMVPGRIVVLAAFPVTPNGKLDRAALPAPPETQDLVTPPEGETQQAIAAIWCEVLGRASVGANQNFFDLGG
NSLAALRVLNALRTHFPDKTIGVPLLFSHQDVASLAAAIDADAVGTTQVVQLNPRGSRPRLYCFPGLMVNTREYAPLVRR
LGPDQPVTGFVCYSLTEERKSVVSVEDIAARYAAHIRTECAGGSATLLGWSWGGVLAFEAARLLAGEVDIGFVGMLDVCN
LDVNFAVGRLADIASADRARLAGEVGAWLDRAPMRAEWENLFARMDDTLFTQFLRYVETIGGDLPADGPGLGSREYELFT
FIDNTLLYRRYSMAPFDVPVRVWLAENSVARGLDLVDWSRYSPRVDQVEVIPGVTHREIVDSARFHDSFARSLAKAWDAP
SRAALAGAAE

Sequences:

>Translated_1370_residues
MAPSPHDLARRFAQLAPEKRRHFLDALAAAGVDFRLLPIPTAPRPNRRAPLSFAQNRMWVAQQMGGNGALNTIAGGLRLD
GALDGDALAAAFSDLSARHEALRTTFALTPEGVPEQVIHETAPIALDHVDLSGAADPDGRLKALSDADAARPFDLLAGPL
TRATHVRLAPDAHVLQLTQHHIVSDGASLSVLLRDLMALYAARRAGTSSPLTPPALHYADYAIWQRNWLEAGEMARQIEG
WRTRLGDGGALLALPTDRPRPATQSHRGGRHAVTLAPELAARLRTVTQEAGASTAMGLMAVLLALLFRLTGERDLRLGIP
ASNRDRPETQDLVGLLVNTLVIRAEVTSTTSYRALLDAARAALLDAQTLQDAPFEEVVEALQPERSLARSPLFQVMHSHL
VDERPARMAGLTLSPVARDTGAIAFDLVLETTEQPDGVIIAAFGYARDLFRAATVARIAEHFLALAERCLTVPDAPIGDF
PLVDEATLDRLSAPWPGDLPLADGLVPHLIAEAAQRRPDAPAVICGDETLSFAELERAANRIAHHLLGLGVGAETRVAVG
LRRGPGAVAAFLGVLKAGAAFVPFDPDHPAERIADVVTDSGATFAVVNADGPALPQAVTALVPECLDLAALPETAPQVVI
HPEQLAYVIYTSGSTGRPKGVGVPHGALAMHVRATGALYGTGEETRELHFLSFAFDGAHERWMVPLAFGGAIVLRDQGLW
SAEETRHALARHRVTHAGFPPAYLTQLAEWVESAGDPPPVQVYSFGGEAMPRAGFETVKRALRPQVLINGYGPTEAVISP
MAWRVPASESFDGPYAPIGRAVGQRRAYVLDDGLQPVPIGVAGELYLSGEGLARGYLGRAGATAERFLPDPFGPCGGRMY
RTGDRVRWLADGTVEYLGRADQQIKLRGFRIEPGEIEAQLRQEETVREALVMLRTDGAAPRLVAYVTPAEGAVAEEATLR
AALLRRLPDYMVPGRIVVLAAFPVTPNGKLDRAALPAPPETQDLVTPPEGETQQAIAAIWCEVLGRASVGANQNFFDLGG
NSLAALRVLNALRTHFPDKTIGVPLLFSHQDVASLAAAIDADAVGTTQVVQLNPRGSRPRLYCFPGLMVNTREYAPLVRR
LGPDQPVTGFVCYSLTEERKSVVSVEDIAARYAAHIRTECAGGSATLLGWSWGGVLAFEAARLLAGEVDIGFVGMLDVCN
LDVNFAVGRLADIASADRARLAGEVGAWLDRAPMRAEWENLFARMDDTLFTQFLRYVETIGGDLPADGPGLGSREYELFT
FIDNTLLYRRYSMAPFDVPVRVWLAENSVARGLDLVDWSRYSPRVDQVEVIPGVTHREIVDSARFHDSFARSLAKAWDAP
SRAALAGAAE
>Mature_1369_residues
APSPHDLARRFAQLAPEKRRHFLDALAAAGVDFRLLPIPTAPRPNRRAPLSFAQNRMWVAQQMGGNGALNTIAGGLRLDG
ALDGDALAAAFSDLSARHEALRTTFALTPEGVPEQVIHETAPIALDHVDLSGAADPDGRLKALSDADAARPFDLLAGPLT
RATHVRLAPDAHVLQLTQHHIVSDGASLSVLLRDLMALYAARRAGTSSPLTPPALHYADYAIWQRNWLEAGEMARQIEGW
RTRLGDGGALLALPTDRPRPATQSHRGGRHAVTLAPELAARLRTVTQEAGASTAMGLMAVLLALLFRLTGERDLRLGIPA
SNRDRPETQDLVGLLVNTLVIRAEVTSTTSYRALLDAARAALLDAQTLQDAPFEEVVEALQPERSLARSPLFQVMHSHLV
DERPARMAGLTLSPVARDTGAIAFDLVLETTEQPDGVIIAAFGYARDLFRAATVARIAEHFLALAERCLTVPDAPIGDFP
LVDEATLDRLSAPWPGDLPLADGLVPHLIAEAAQRRPDAPAVICGDETLSFAELERAANRIAHHLLGLGVGAETRVAVGL
RRGPGAVAAFLGVLKAGAAFVPFDPDHPAERIADVVTDSGATFAVVNADGPALPQAVTALVPECLDLAALPETAPQVVIH
PEQLAYVIYTSGSTGRPKGVGVPHGALAMHVRATGALYGTGEETRELHFLSFAFDGAHERWMVPLAFGGAIVLRDQGLWS
AEETRHALARHRVTHAGFPPAYLTQLAEWVESAGDPPPVQVYSFGGEAMPRAGFETVKRALRPQVLINGYGPTEAVISPM
AWRVPASESFDGPYAPIGRAVGQRRAYVLDDGLQPVPIGVAGELYLSGEGLARGYLGRAGATAERFLPDPFGPCGGRMYR
TGDRVRWLADGTVEYLGRADQQIKLRGFRIEPGEIEAQLRQEETVREALVMLRTDGAAPRLVAYVTPAEGAVAEEATLRA
ALLRRLPDYMVPGRIVVLAAFPVTPNGKLDRAALPAPPETQDLVTPPEGETQQAIAAIWCEVLGRASVGANQNFFDLGGN
SLAALRVLNALRTHFPDKTIGVPLLFSHQDVASLAAAIDADAVGTTQVVQLNPRGSRPRLYCFPGLMVNTREYAPLVRRL
GPDQPVTGFVCYSLTEERKSVVSVEDIAARYAAHIRTECAGGSATLLGWSWGGVLAFEAARLLAGEVDIGFVGMLDVCNL
DVNFAVGRLADIASADRARLAGEVGAWLDRAPMRAEWENLFARMDDTLFTQFLRYVETIGGDLPADGPGLGSREYELFTF
IDNTLLYRRYSMAPFDVPVRVWLAENSVARGLDLVDWSRYSPRVDQVEVIPGVTHREIVDSARFHDSFARSLAKAWDAPS
RAALAGAAE

Specific function: Activates the 7th to 12th amino acids (Val, D-Val, Trp, D-Leu, Xaa and D-Leu) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 8th (D-Val), the 10th (D- Leu) an

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=578, Percent_Identity=21.280276816609, Blast_Score=84, Evalue=1e-15,
Organism=Escherichia coli, GI1786801, Length=713, Percent_Identity=32.8190743338008, Blast_Score=274, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17550940, Length=931, Percent_Identity=21.5896885069817, Blast_Score=106, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17556356, Length=645, Percent_Identity=22.9457364341085, Blast_Score=105, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17560308, Length=364, Percent_Identity=24.7252747252747, Blast_Score=75, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319591, Length=965, Percent_Identity=24.0414507772021, Blast_Score=205, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24648676, Length=642, Percent_Identity=27.5700934579439, Blast_Score=173, Evalue=6e-43,
Organism=Drosophila melanogaster, GI18859661, Length=519, Percent_Identity=25.4335260115607, Blast_Score=91, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24581924, Length=382, Percent_Identity=26.1780104712042, Blast_Score=76, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19922652, Length=558, Percent_Identity=22.5806451612903, Blast_Score=71, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR023213
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 147192; Mature: 147061

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSPHDLARRFAQLAPEKRRHFLDALAAAGVDFRLLPIPTAPRPNRRAPLSFAQNRMWV
CCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHCHHHH
AQQMGGNGALNTIAGGLRLDGALDGDALAAAFSDLSARHEALRTTFALTPEGVPEQVIHE
HHHCCCCCCHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
TAPIALDHVDLSGAADPDGRLKALSDADAARPFDLLAGPLTRATHVRLAPDAHVLQLTQH
CCCCEEEEEECCCCCCCCCCEEECCCCCCCCCHHHHHCCCCCCEEEEECCCHHHHHHHHH
HIVSDGASLSVLLRDLMALYAARRAGTSSPLTPPALHYADYAIWQRNWLEAGEMARQIEG
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WRTRLGDGGALLALPTDRPRPATQSHRGGRHAVTLAPELAARLRTVTQEAGASTAMGLMA
HHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCHHHHHHHH
VLLALLFRLTGERDLRLGIPASNRDRPETQDLVGLLVNTLVIRAEVTSTTSYRALLDAAR
HHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHH
AALLDAQTLQDAPFEEVVEALQPERSLARSPLFQVMHSHLVDERPARMAGLTLSPVARDT
HHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCEECCCCCCC
GAIAFDLVLETTEQPDGVIIAAFGYARDLFRAATVARIAEHFLALAERCLTVPDAPIGDF
CCEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PLVDEATLDRLSAPWPGDLPLADGLVPHLIAEAAQRRPDAPAVICGDETLSFAELERAAN
CCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHH
RIAHHLLGLGVGAETRVAVGLRRGPGAVAAFLGVLKAGAAFVPFDPDHPAERIADVVTDS
HHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHCCC
GATFAVVNADGPALPQAVTALVPECLDLAALPETAPQVVIHPEQLAYVIYTSGSTGRPKG
CCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHEEEEEEECCCCCCCCC
VGVPHGALAMHVRATGALYGTGEETRELHFLSFAFDGAHERWMVPLAFGGAIVLRDQGLW
CCCCCCCEEEEEEECEEEECCCCCCCEEEEEEEEECCCCCEEEEEEEECCEEEEECCCCC
SAEETRHALARHRVTHAGFPPAYLTQLAEWVESAGDPPPVQVYSFGGEAMPRAGFETVKR
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHH
ALRPQVLINGYGPTEAVISPMAWRVPASESFDGPYAPIGRAVGQRRAYVLDDGLQPVPIG
HCCCEEEEECCCCHHHHHCCHHEECCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCC
VAGELYLSGEGLARGYLGRAGATAERFLPDPFGPCGGRMYRTGDRVRWLADGTVEYLGRA
CEEEEEECCCCHHHHCCCCCCCCHHHCCCCCCCCCCCCEEECCCCEEEEECCHHHHHCCC
DQQIKLRGFRIEPGEIEAQLRQEETVREALVMLRTDGAAPRLVAYVTPAEGAVAEEATLR
CCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHH
AALLRRLPDYMVPGRIVVLAAFPVTPNGKLDRAALPAPPETQDLVTPPEGETQQAIAAIW
HHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
CEVLGRASVGANQNFFDLGGNSLAALRVLNALRTHFPDKTIGVPLLFSHQDVASLAAAID
HHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHC
ADAVGTTQVVQLNPRGSRPRLYCFPGLMVNTREYAPLVRRLGPDQPVTGFVCYSLTEERK
CCCCCCEEEEEECCCCCCCEEEEECCEEECCHHHHHHHHHCCCCCCCCEEEEEEEHHHHH
SVVSVEDIAARYAAHIRTECAGGSATLLGWSWGGVLAFEAARLLAGEVDIGFVGMLDVCN
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEHHHHHC
LDVNFAVGRLADIASADRARLAGEVGAWLDRAPMRAEWENLFARMDDTLFTQFLRYVETI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GGDLPADGPGLGSREYELFTFIDNTLLYRRYSMAPFDVPVRVWLAENSVARGLDLVDWSR
CCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCEEEEEECCHHHCCCCCCCCCC
YSPRVDQVEVIPGVTHREIVDSARFHDSFARSLAKAWDAPSRAALAGAAE
CCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCC
>Mature Secondary Structure 
APSPHDLARRFAQLAPEKRRHFLDALAAAGVDFRLLPIPTAPRPNRRAPLSFAQNRMWV
CCCHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHCHHHH
AQQMGGNGALNTIAGGLRLDGALDGDALAAAFSDLSARHEALRTTFALTPEGVPEQVIHE
HHHCCCCCCHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
TAPIALDHVDLSGAADPDGRLKALSDADAARPFDLLAGPLTRATHVRLAPDAHVLQLTQH
CCCCEEEEEECCCCCCCCCCEEECCCCCCCCCHHHHHCCCCCCEEEEECCCHHHHHHHHH
HIVSDGASLSVLLRDLMALYAARRAGTSSPLTPPALHYADYAIWQRNWLEAGEMARQIEG
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
WRTRLGDGGALLALPTDRPRPATQSHRGGRHAVTLAPELAARLRTVTQEAGASTAMGLMA
HHHHCCCCCEEEEECCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCHHHHHHHH
VLLALLFRLTGERDLRLGIPASNRDRPETQDLVGLLVNTLVIRAEVTSTTSYRALLDAAR
HHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHH
AALLDAQTLQDAPFEEVVEALQPERSLARSPLFQVMHSHLVDERPARMAGLTLSPVARDT
HHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCEECCCCCCC
GAIAFDLVLETTEQPDGVIIAAFGYARDLFRAATVARIAEHFLALAERCLTVPDAPIGDF
CCEEEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PLVDEATLDRLSAPWPGDLPLADGLVPHLIAEAAQRRPDAPAVICGDETLSFAELERAAN
CCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHH
RIAHHLLGLGVGAETRVAVGLRRGPGAVAAFLGVLKAGAAFVPFDPDHPAERIADVVTDS
HHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHCCC
GATFAVVNADGPALPQAVTALVPECLDLAALPETAPQVVIHPEQLAYVIYTSGSTGRPKG
CCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHEEEEEEECCCCCCCCC
VGVPHGALAMHVRATGALYGTGEETRELHFLSFAFDGAHERWMVPLAFGGAIVLRDQGLW
CCCCCCCEEEEEEECEEEECCCCCCCEEEEEEEEECCCCCEEEEEEEECCEEEEECCCCC
SAEETRHALARHRVTHAGFPPAYLTQLAEWVESAGDPPPVQVYSFGGEAMPRAGFETVKR
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHH
ALRPQVLINGYGPTEAVISPMAWRVPASESFDGPYAPIGRAVGQRRAYVLDDGLQPVPIG
HCCCEEEEECCCCHHHHHCCHHEECCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCC
VAGELYLSGEGLARGYLGRAGATAERFLPDPFGPCGGRMYRTGDRVRWLADGTVEYLGRA
CEEEEEECCCCHHHHCCCCCCCCHHHCCCCCCCCCCCCEEECCCCEEEEECCHHHHHCCC
DQQIKLRGFRIEPGEIEAQLRQEETVREALVMLRTDGAAPRLVAYVTPAEGAVAEEATLR
CCEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHH
AALLRRLPDYMVPGRIVVLAAFPVTPNGKLDRAALPAPPETQDLVTPPEGETQQAIAAIW
HHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
CEVLGRASVGANQNFFDLGGNSLAALRVLNALRTHFPDKTIGVPLLFSHQDVASLAAAID
HHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHHC
ADAVGTTQVVQLNPRGSRPRLYCFPGLMVNTREYAPLVRRLGPDQPVTGFVCYSLTEERK
CCCCCCEEEEEECCCCCCCEEEEECCEEECCHHHHHHHHHCCCCCCCCEEEEEEEHHHHH
SVVSVEDIAARYAAHIRTECAGGSATLLGWSWGGVLAFEAARLLAGEVDIGFVGMLDVCN
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCEEEHHHHHC
LDVNFAVGRLADIASADRARLAGEVGAWLDRAPMRAEWENLFARMDDTLFTQFLRYVETI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GGDLPADGPGLGSREYELFTFIDNTLLYRRYSMAPFDVPVRVWLAENSVARGLDLVDWSR
CCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCEEEEEECCHHHCCCCCCCCCC
YSPRVDQVEVIPGVTHREIVDSARFHDSFARSLAKAWDAPSRAALAGAAE
CCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA