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The map label for this gene is mmgC [H]

Identifier: 154246622

GI number: 154246622

Start: 2970204

End: 2971499

Strand: Reverse

Name: mmgC [H]

Synonym: Xaut_2682

Alternate gene names: 154246622

Gene position: 2971499-2970204 (Counterclockwise)

Preceding gene: 154246623

Following gene: 154246620

Centisome position: 55.97

GC content: 65.66

Gene sequence:

>1296_bases
ATGCCGATCGACTTCACGCTCACGGCAAACCAGAAGCGGCTGCGGACCGTAGCGCGGGAGTTCGCCAACGACATCCTCGC
CCCCCGTGTCCGGCGAGCTGACGAGGAGCCGGACCCGCAGAAGGCCTTCCAGGACATGAAGGGCGCCTACGTGGAAGCCT
ACAAGCTGGGCTTCGCCATGGGATTCGTCCCCAAGCGCTATGGCGGCGGCGGCATCAGCAGCCTTGATCTCCAGGTGGTT
GCCGAAGAGATCTGCGCCGTGGACCCGGGCTTCGCAACCATCCTTCTGGTCAATGGCCTCGCCCTCATGCCCTTGGTCTG
GTTCGGCAACGAGCGGCAGAAGCAGAAGTGGCTGACGGCGGCGACGGGCGATCCGCGCGGCGAATATCTTGCGGCGTGGA
CGGTCAGCGAGGCGGCGGGGTCGCCCGGGGGCACCGCCAATTTCGACCATCCGGCGCCGTGGCCGGCGGGCGTTTCGCTG
ACGGCGACCCATGACCGCAAGAATGGCGAATACATCCTGAATGGCCGCAAATATTGGCCCTGCAATGCCGGCGGCTGGGA
CCTCGCGGGCGCAAACATCAATATCTGCATCGTCCGCACCACCCCGAAGCGCGGCGGCACGGAAGGGCTGTCGGCGATCA
TCGTGCCGCGGGGCACGGCCGGTGTCTTCTACGAGCCGCCTATCTCCAAGATCGGCCACCGCATCTGCCAGAACAATTCC
ATCGTCTTCCAGGATTGCCGCGTGCCGGAGGAGAACGCCTTTGCGATCGGCGATGGCGACCTCGCGATTGCCCGCGCCTT
CACCTGGTCCGGCCCGGTGGCCGCCATCGCCGCGGTCGGGGTCGCGCGGTCCGCCTATGAGTACGTGCTCGACTGGGCGA
AGACCCACACCGCCGGCGGCCCGGAGCCGATCATCAACCATCAGGCGGTCGGCTATGCGCTCGCCGACGTGGCGATGAAG
ATCGAGGCCTGCCGTGCCTTCGCCTGGAAGGCGGCGCACTATCTCGACCGCAACGAGAGCCAGGGCCATGCCATCTGCGC
CATGGCAAAGGTCTTTTGTGGAGAAACGTTGTTCGGCGCTGTGTTTGGGGCCATGCGGGTCATGGGGGTGAATGCCCTCG
ACCGGCGGCATCCGCTGGAGCGCTACCTGCGCGAGGCCGCCGTCTTCCCTCTCTATGACGCGGGCAATCTGGGCATGCAG
ATGCGCAAGATCTGGTCCGTCATGCGCCATCCCGATTTCGATCCGCGCGCTTTCATGGACCTATCGCCGACACCGTTCGA
CAAGACCCTGAGATAG

Upstream 100 bases:

>100_bases
CGGCGAGATCGTTAGGCATGGTCGCCGAGAGCCGCAATTCCCGAACCTCTTTTGGCATATAAATTGCTCAAAAGAGGCTT
TACCTGTTGGGAGACCGATT

Downstream 100 bases:

>100_bases
CGCCGCACGCCGCCGTCAGGCGAGGGGTACGAAGCGGAAGCGGCAGACCTGCCCATCATCCCGCTGCATGCACTCCTCCT
GGTCCACACCCGCACCCATC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MPIDFTLTANQKRLRTVAREFANDILAPRVRRADEEPDPQKAFQDMKGAYVEAYKLGFAMGFVPKRYGGGGISSLDLQVV
AEEICAVDPGFATILLVNGLALMPLVWFGNERQKQKWLTAATGDPRGEYLAAWTVSEAAGSPGGTANFDHPAPWPAGVSL
TATHDRKNGEYILNGRKYWPCNAGGWDLAGANINICIVRTTPKRGGTEGLSAIIVPRGTAGVFYEPPISKIGHRICQNNS
IVFQDCRVPEENAFAIGDGDLAIARAFTWSGPVAAIAAVGVARSAYEYVLDWAKTHTAGGPEPIINHQAVGYALADVAMK
IEACRAFAWKAAHYLDRNESQGHAICAMAKVFCGETLFGAVFGAMRVMGVNALDRRHPLERYLREAAVFPLYDAGNLGMQ
MRKIWSVMRHPDFDPRAFMDLSPTPFDKTLR

Sequences:

>Translated_431_residues
MPIDFTLTANQKRLRTVAREFANDILAPRVRRADEEPDPQKAFQDMKGAYVEAYKLGFAMGFVPKRYGGGGISSLDLQVV
AEEICAVDPGFATILLVNGLALMPLVWFGNERQKQKWLTAATGDPRGEYLAAWTVSEAAGSPGGTANFDHPAPWPAGVSL
TATHDRKNGEYILNGRKYWPCNAGGWDLAGANINICIVRTTPKRGGTEGLSAIIVPRGTAGVFYEPPISKIGHRICQNNS
IVFQDCRVPEENAFAIGDGDLAIARAFTWSGPVAAIAAVGVARSAYEYVLDWAKTHTAGGPEPIINHQAVGYALADVAMK
IEACRAFAWKAAHYLDRNESQGHAICAMAKVFCGETLFGAVFGAMRVMGVNALDRRHPLERYLREAAVFPLYDAGNLGMQ
MRKIWSVMRHPDFDPRAFMDLSPTPFDKTLR
>Mature_430_residues
PIDFTLTANQKRLRTVAREFANDILAPRVRRADEEPDPQKAFQDMKGAYVEAYKLGFAMGFVPKRYGGGGISSLDLQVVA
EEICAVDPGFATILLVNGLALMPLVWFGNERQKQKWLTAATGDPRGEYLAAWTVSEAAGSPGGTANFDHPAPWPAGVSLT
ATHDRKNGEYILNGRKYWPCNAGGWDLAGANINICIVRTTPKRGGTEGLSAIIVPRGTAGVFYEPPISKIGHRICQNNSI
VFQDCRVPEENAFAIGDGDLAIARAFTWSGPVAAIAAVGVARSAYEYVLDWAKTHTAGGPEPIINHQAVGYALADVAMKI
EACRAFAWKAAHYLDRNESQGHAICAMAKVFCGETLFGAVFGAMRVMGVNALDRRHPLERYLREAAVFPLYDAGNLGMQM
RKIWSVMRHPDFDPRAFMDLSPTPFDKTLR

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=422, Percent_Identity=28.6729857819905, Blast_Score=155, Evalue=5e-38,
Organism=Homo sapiens, GI187960098, Length=422, Percent_Identity=28.6729857819905, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI4557233, Length=392, Percent_Identity=27.8061224489796, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI226958412, Length=418, Percent_Identity=24.6411483253589, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI7656849, Length=406, Percent_Identity=24.6305418719212, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI4501859, Length=413, Percent_Identity=25.4237288135593, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI226958414, Length=352, Percent_Identity=25, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI4557235, Length=383, Percent_Identity=24.0208877284595, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI76496475, Length=383, Percent_Identity=24.0208877284595, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI21361497, Length=403, Percent_Identity=26.302729528536, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4503943, Length=366, Percent_Identity=22.6775956284153, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI7669494, Length=366, Percent_Identity=22.6775956284153, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI38505218, Length=338, Percent_Identity=24.5562130177515, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI87081958, Length=377, Percent_Identity=24.4031830238727, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534899, Length=395, Percent_Identity=28.6075949367089, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17569725, Length=397, Percent_Identity=27.9596977329975, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17570075, Length=394, Percent_Identity=28.1725888324873, Blast_Score=144, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI17538396, Length=398, Percent_Identity=25.3768844221106, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17508101, Length=404, Percent_Identity=22.7722772277228, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17533517, Length=384, Percent_Identity=23.1770833333333, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17506239, Length=413, Percent_Identity=22.5181598062954, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=295, Percent_Identity=24.7457627118644, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=399, Percent_Identity=23.5588972431078, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=302, Percent_Identity=25.8278145695364, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71985184, Length=375, Percent_Identity=24.2666666666667, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24660351, Length=399, Percent_Identity=28.0701754385965, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI21356377, Length=390, Percent_Identity=27.9487179487179, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24666513, Length=418, Percent_Identity=26.7942583732057, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24646207, Length=391, Percent_Identity=27.8772378516624, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21355753, Length=414, Percent_Identity=26.0869565217391, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI281363737, Length=399, Percent_Identity=22.8070175438596, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19920834, Length=339, Percent_Identity=25.6637168141593, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 47035; Mature: 46904

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDFTLTANQKRLRTVAREFANDILAPRVRRADEEPDPQKAFQDMKGAYVEAYKLGFAM
CCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHH
GFVPKRYGGGGISSLDLQVVAEEICAVDPGFATILLVNGLALMPLVWFGNERQKQKWLTA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHEECCCCHHHHHEEEE
ATGDPRGEYLAAWTVSEAAGSPGGTANFDHPAPWPAGVSLTATHDRKNGEYILNGRKYWP
CCCCCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCEECC
CNAGGWDLAGANINICIVRTTPKRGGTEGLSAIIVPRGTAGVFYEPPISKIGHRICQNNS
CCCCCCEECCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCEECCCHHHHHHHHHCCCC
IVFQDCRVPEENAFAIGDGDLAIARAFTWSGPVAAIAAVGVARSAYEYVLDWAKTHTAGG
EEEEECCCCCCCEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PEPIINHQAVGYALADVAMKIEACRAFAWKAAHYLDRNESQGHAICAMAKVFCGETLFGA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHH
VFGAMRVMGVNALDRRHPLERYLREAAVFPLYDAGNLGMQMRKIWSVMRHPDFDPRAFMD
HHHHHHHHCCCHHHHCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCCCCCEEEC
LSPTPFDKTLR
CCCCCCHHCCC
>Mature Secondary Structure 
PIDFTLTANQKRLRTVAREFANDILAPRVRRADEEPDPQKAFQDMKGAYVEAYKLGFAM
CEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHH
GFVPKRYGGGGISSLDLQVVAEEICAVDPGFATILLVNGLALMPLVWFGNERQKQKWLTA
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHEECCCCHHHHHEEEE
ATGDPRGEYLAAWTVSEAAGSPGGTANFDHPAPWPAGVSLTATHDRKNGEYILNGRKYWP
CCCCCCCCEEEEEEEHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCEECC
CNAGGWDLAGANINICIVRTTPKRGGTEGLSAIIVPRGTAGVFYEPPISKIGHRICQNNS
CCCCCCEECCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCEECCCHHHHHHHHHCCCC
IVFQDCRVPEENAFAIGDGDLAIARAFTWSGPVAAIAAVGVARSAYEYVLDWAKTHTAGG
EEEEECCCCCCCEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PEPIINHQAVGYALADVAMKIEACRAFAWKAAHYLDRNESQGHAICAMAKVFCGETLFGA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCHHHHHH
VFGAMRVMGVNALDRRHPLERYLREAAVFPLYDAGNLGMQMRKIWSVMRHPDFDPRAFMD
HHHHHHHHCCCHHHHCCHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHCCCCCCCEEEC
LSPTPFDKTLR
CCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]