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The map label for this gene is bcd [H]

Identifier: 154246620

GI number: 154246620

Start: 2967891

End: 2969255

Strand: Reverse

Name: bcd [H]

Synonym: Xaut_2680

Alternate gene names: 154246620

Gene position: 2969255-2967891 (Counterclockwise)

Preceding gene: 154246622

Following gene: 154246618

Centisome position: 55.93

GC content: 63.96

Gene sequence:

>1365_bases
ATGGCAATCGACTTCACCATGTCGCCGGAACAACGGCAGATCCAGGCGATGGCTCGCGAATTTGCAGAGAATGTGCTGGC
TCCCGTCGTTCCCGAGGCAGATCGCGAGCCAGATCCTCTGCTGGCCCATGCCAGGACCAAGGGCGCCTATGTCGAGGCGT
ACAAGGCCGGCATCGCCATGGCCATGCTGCCGAAGGAATATGGCGGCGGCGGCCTCTCGTGCCTCGATTTGACCATCGCG
GCCGAAGAGATCTGCGCCGTCGATCCTGGCTTTGCCTGCACCGTGCTCTGCAATGGCCTCGGCCTGATGCCGGTCGCCTG
GTATGGCACCGAGGAGCAGAAGAAGCGCTTCATCGGCGCGGCCACCTCCGACCCGACCGGCGAATTCCTAGGCGGCTGGA
CCGCCGGCGAGCCTCCGGGCGGCACCGGCGGCACCGCGAATTTCGACAACCCTTTCCCGCGGCCTGCGGGTATCGGGCTG
ACTGCGACCCGCGACGGTGACCATTATATCCTCAATGGCCGGAAGAAATGGTCTTCGGCAGGTGGCTGGGATGCCAAGGG
GGTCAATGCGCAGACGGTGATCGTGCGGACCGACGGCGACGTCGGCGGCACCAAGGGCCTGTCCGCCATCGTGGTCGAGC
GCGGAACGCCCGGCATCTCGTATGAATTCGTCAACAAGGAGGGGCACCGTACCGCGTCCAACGCCCTCATCACCTTCGAC
AACGCGCGCGTTCCGGTCGACAACCTTCTGCCCGGCGCGGCCGGCAATGGCGATTTCGTCATCAACCGCAATTTCGCCTG
GTCCGGCCCCGTGGCCGGCATCGCGGCGGTGGGCATGGCCCGCTCGGCCTACGAGGCCGCCCTCAAGTTCTGCAAGGCCA
ACACGGCGGGCTCCCTGACACCGATCATCCGCTTCCAGAATGTCGGCTACATTCTCGGCGACTGTGCCGCCAAGATCGAA
TCGGCCCGCTATTTCTGCTGGCGCGCCTCGGACTATCTCGACAAGCATGAGCAGCATGCCGAGCTCGTCGGCGCCATGTG
CAAGATCAACACCACCGAGGCCATGTTTGACGTCATCTACAAGTGCATGCAGGTGGTGGGTGTAAATAGCCTCAGCACCG
AGTATCCGTTCGGCCGTTTCCTGCGGGAGGCCTCCGTCCTGCCCATCTATGACGGCGGCAACATGGGCATGCAGCGCCGC
CGCGTTCACGGCGTCATTGCCGACGAGGGGTTCAATCCGCGGGCGGTGATGGAGGACAGCACGATCGTCTTCGAAAAGTC
GATGGAGAGCATCGGCACCGTTGCCGACTGGGACCGCCAATACTCCAATTCCGGCTCCACTCCGTTCGTATCCGCGGCCG
AATAA

Upstream 100 bases:

>100_bases
TCCTGACATCGCCTTTCCGCCACGCCCGACACCCGTCGCGGCGAACGGGTCTGCGCGGCCATGGACGGTGCGAGCGGAAC
AACAACGAAGGGGAACTTCA

Downstream 100 bases:

>100_bases
GCTGAAACAACCGTGCGCGGACGTCGCAACTGGCGTCCGCGCACGTGGAGCAGATGCCATCGCCCTCTCTCCGAATTGGC
CACTGCCACGGCCTGTGGAA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MAIDFTMSPEQRQIQAMAREFAENVLAPVVPEADREPDPLLAHARTKGAYVEAYKAGIAMAMLPKEYGGGGLSCLDLTIA
AEEICAVDPGFACTVLCNGLGLMPVAWYGTEEQKKRFIGAATSDPTGEFLGGWTAGEPPGGTGGTANFDNPFPRPAGIGL
TATRDGDHYILNGRKKWSSAGGWDAKGVNAQTVIVRTDGDVGGTKGLSAIVVERGTPGISYEFVNKEGHRTASNALITFD
NARVPVDNLLPGAAGNGDFVINRNFAWSGPVAGIAAVGMARSAYEAALKFCKANTAGSLTPIIRFQNVGYILGDCAAKIE
SARYFCWRASDYLDKHEQHAELVGAMCKINTTEAMFDVIYKCMQVVGVNSLSTEYPFGRFLREASVLPIYDGGNMGMQRR
RVHGVIADEGFNPRAVMEDSTIVFEKSMESIGTVADWDRQYSNSGSTPFVSAAE

Sequences:

>Translated_454_residues
MAIDFTMSPEQRQIQAMAREFAENVLAPVVPEADREPDPLLAHARTKGAYVEAYKAGIAMAMLPKEYGGGGLSCLDLTIA
AEEICAVDPGFACTVLCNGLGLMPVAWYGTEEQKKRFIGAATSDPTGEFLGGWTAGEPPGGTGGTANFDNPFPRPAGIGL
TATRDGDHYILNGRKKWSSAGGWDAKGVNAQTVIVRTDGDVGGTKGLSAIVVERGTPGISYEFVNKEGHRTASNALITFD
NARVPVDNLLPGAAGNGDFVINRNFAWSGPVAGIAAVGMARSAYEAALKFCKANTAGSLTPIIRFQNVGYILGDCAAKIE
SARYFCWRASDYLDKHEQHAELVGAMCKINTTEAMFDVIYKCMQVVGVNSLSTEYPFGRFLREASVLPIYDGGNMGMQRR
RVHGVIADEGFNPRAVMEDSTIVFEKSMESIGTVADWDRQYSNSGSTPFVSAAE
>Mature_453_residues
AIDFTMSPEQRQIQAMAREFAENVLAPVVPEADREPDPLLAHARTKGAYVEAYKAGIAMAMLPKEYGGGGLSCLDLTIAA
EEICAVDPGFACTVLCNGLGLMPVAWYGTEEQKKRFIGAATSDPTGEFLGGWTAGEPPGGTGGTANFDNPFPRPAGIGLT
ATRDGDHYILNGRKKWSSAGGWDAKGVNAQTVIVRTDGDVGGTKGLSAIVVERGTPGISYEFVNKEGHRTASNALITFDN
ARVPVDNLLPGAAGNGDFVINRNFAWSGPVAGIAAVGMARSAYEAALKFCKANTAGSLTPIIRFQNVGYILGDCAAKIES
ARYFCWRASDYLDKHEQHAELVGAMCKINTTEAMFDVIYKCMQVVGVNSLSTEYPFGRFLREASVLPIYDGGNMGMQRRR
VHGVIADEGFNPRAVMEDSTIVFEKSMESIGTVADWDRQYSNSGSTPFVSAAE

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557231, Length=404, Percent_Identity=29.2079207920792, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI187960098, Length=404, Percent_Identity=29.2079207920792, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI4557233, Length=403, Percent_Identity=31.2655086848635, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4501859, Length=397, Percent_Identity=25.9445843828715, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI226958412, Length=412, Percent_Identity=24.2718446601942, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI7656849, Length=395, Percent_Identity=26.0759493670886, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI21361497, Length=381, Percent_Identity=26.246719160105, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI226958414, Length=355, Percent_Identity=24.5070422535211, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI4557235, Length=341, Percent_Identity=27.2727272727273, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI76496475, Length=341, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4501857, Length=416, Percent_Identity=24.2788461538462, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI7669494, Length=341, Percent_Identity=23.7536656891496, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4503943, Length=332, Percent_Identity=23.7951807228916, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI87081958, Length=387, Percent_Identity=22.2222222222222, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=393, Percent_Identity=28.7531806615776, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17569725, Length=415, Percent_Identity=27.4698795180723, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17570075, Length=419, Percent_Identity=26.7303102625298, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17508101, Length=392, Percent_Identity=26.0204081632653, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17506239, Length=403, Percent_Identity=26.0545905707196, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17533517, Length=385, Percent_Identity=25.1948051948052, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17538396, Length=391, Percent_Identity=24.5524296675192, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=402, Percent_Identity=26.3681592039801, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=290, Percent_Identity=25.8620689655172, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17534353, Length=398, Percent_Identity=25.1256281407035, Blast_Score=83, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71985192, Length=358, Percent_Identity=25.9776536312849, Blast_Score=82, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI32563615, Length=201, Percent_Identity=31.3432835820896, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=289, Percent_Identity=24.9134948096886, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24660351, Length=396, Percent_Identity=27.2727272727273, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI21356377, Length=409, Percent_Identity=30.3178484107579, Blast_Score=131, Evalue=9e-31,
Organism=Drosophila melanogaster, GI24646207, Length=389, Percent_Identity=28.7917737789203, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24666513, Length=395, Percent_Identity=25.3164556962025, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355753, Length=391, Percent_Identity=25.0639386189258, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19920834, Length=337, Percent_Identity=25.2225519287834, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281363737, Length=345, Percent_Identity=25.5072463768116, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 48535; Mature: 48404

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIDFTMSPEQRQIQAMAREFAENVLAPVVPEADREPDPLLAHARTKGAYVEAYKAGIAM
CEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHCEEE
AMLPKEYGGGGLSCLDLTIAAEEICAVDPGFACTVLCNGLGLMPVAWYGTEEQKKRFIGA
EECCHHCCCCCEEEEEEEEEHHHHHCCCCCCEEEEECCCCCCCEEEECCCHHHHHHEEEC
ATSDPTGEFLGGWTAGEPPGGTGGTANFDNPFPRPAGIGLTATRDGDHYILNGRKKWSSA
CCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCHHCCCC
GGWDAKGVNAQTVIVRTDGDVGGTKGLSAIVVERGTPGISYEFVNKEGHRTASNALITFD
CCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCEEEEEC
NARVPVDNLLPGAAGNGDFVINRNFAWSGPVAGIAAVGMARSAYEAALKFCKANTAGSLT
CCCCCHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
PIIRFQNVGYILGDCAAKIESARYFCWRASDYLDKHEQHAELVGAMCKINTTEAMFDVIY
EEEEECCCCEEEHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KCMQVVGVNSLSTEYPFGRFLREASVLPIYDGGNMGMQRRRVHGVIADEGFNPRAVMEDS
HHHHHHCCCCCCCCCCHHHHHHHCCEEEEEECCCCCCHHHHHEEEEECCCCCCCEEECCC
TIVFEKSMESIGTVADWDRQYSNSGSTPFVSAAE
EEEEHHHHHHHCCHHHHHHHHCCCCCCCEEECCC
>Mature Secondary Structure 
AIDFTMSPEQRQIQAMAREFAENVLAPVVPEADREPDPLLAHARTKGAYVEAYKAGIAM
EEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHCEEE
AMLPKEYGGGGLSCLDLTIAAEEICAVDPGFACTVLCNGLGLMPVAWYGTEEQKKRFIGA
EECCHHCCCCCEEEEEEEEEHHHHHCCCCCCEEEEECCCCCCCEEEECCCHHHHHHEEEC
ATSDPTGEFLGGWTAGEPPGGTGGTANFDNPFPRPAGIGLTATRDGDHYILNGRKKWSSA
CCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCHHCCCC
GGWDAKGVNAQTVIVRTDGDVGGTKGLSAIVVERGTPGISYEFVNKEGHRTASNALITFD
CCCCCCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCCEEEEEC
NARVPVDNLLPGAAGNGDFVINRNFAWSGPVAGIAAVGMARSAYEAALKFCKANTAGSLT
CCCCCHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
PIIRFQNVGYILGDCAAKIESARYFCWRASDYLDKHEQHAELVGAMCKINTTEAMFDVIY
EEEEECCCCEEEHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
KCMQVVGVNSLSTEYPFGRFLREASVLPIYDGGNMGMQRRRVHGVIADEGFNPRAVMEDS
HHHHHHCCCCCCCCCCHHHHHHHCCEEEEEECCCCCCHHHHHEEEEECCCCCCCEEECCC
TIVFEKSMESIGTVADWDRQYSNSGSTPFVSAAE
EEEEHHHHHHHCCHHHHHHHHCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]