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The map label for this gene is dnaQ [H]

Identifier: 154246367

GI number: 154246367

Start: 2710409

End: 2712568

Strand: Reverse

Name: dnaQ [H]

Synonym: Xaut_2426

Alternate gene names: 154246367

Gene position: 2712568-2710409 (Counterclockwise)

Preceding gene: 154246368

Following gene: 154246363

Centisome position: 51.09

GC content: 72.13

Gene sequence:

>2160_bases
ATGAGCTTCGACCGGCGCCTGGCGCTGATCGTGCTCGCGCCGGGCGCACTTCTCGGGCTCTGGCTCCTCGGCGGCGCCGG
CTTGCTTTATGCGGCTCTCGGCCCCGCCGACCGCGCCGCCATCACCGACACCGTCGCGCCGCTGATCGACAGCCACGGCA
TGCTGGTGGTGCTGTGGTGGTTCCTGGCCGCGCTCGGCACCGGCGTCGTCGCCCTGCGCCTGCATGCCATCTATGGGGAG
GCGCCGGCCCGTCTCGCCGATGCCACCCGCGTGCTGGCCGGCGACGCCGCCGCCCCGCCCCTTCCCCCGCAGTCCGGTAC
CGGCATGCGCGCGCTCGGCGAAGCCATCAACGCCCTCGCCGGCCAGCGCCGCGCCCTACAGGACGACATGGCCCGCCTCA
TCGCCGAGGCCAGCCGCGACGTGGCGCTCCAGCGCGACCAGCTCGCCGCCCTGATGGCGGAGCTGGAGCAATCGGTGGTG
GTGCTCAATCTCGAAGGGCGGATCCTGCTCTACAATGCCCGCGCCCGCGCCCTCTTCCGCACCCTCTCGCAGGCGCCGGG
GGGCGTGGCCGGCGCAGAATTGATCGGTCTTGGCCGCTCCATCCATGCGGTCATCGACCGTGCCCTCATCGACCATGCCC
GCGAAGGCATCGCCCGGCGCATCGCCCGCGGCGACGCCCAGGCTTCGGCGCGCTTCGTGACCACGACGCCCCTTGGCCAT
CTCATCCAGGTGTCGCTGGCCCCGGTGCGCGCGGCGGCGGACGACAAGGGCGATGTCACCGGCTTCGTGCTGCTGCTGGA
CGACATCACTGACGAATACGAGGCGCGCTCCCGGCAGGATCGCCGCTGGCTCGACCTCTCGGAGGCGAGCCGGGCCTCCT
TCGCCAGCATGCAGGCCGCCCTCGACATGCTGGACTATCCGGACCTCGAGCCCGCCGACCGCGAGCGCTTCCAGGCCGTG
GTGCGCGACGAGGTGGGGGTGATGAGCCAGCGCCTCACCACGCTCGCCGCCGACGCCTCCCACGACATGAAGACCCGCTG
GCCGCTGCAGGACATGCTGGGCGCCGACCTTGCCGCCGCCGCCGCCCAGCGCATCACCGCCGAGACCGGGCAGGCGGTGG
ACACGGTTGCGGTGGACGCCGACCTCTGGCTGAGCGTGGACAGCTTCGCCCTGATCCAGGCCCTCGCCTTCCTCGCCGCG
CGCCTGTCCGAGACGCTGAAGGCCCCAAATCTCGCCCTGCGCCTCGCGCCGGCGGGCGGGCGAGCCCATCTCGACCTCGC
ATTCCAGGGCACTGGGTCCGGCCTCGACCTCGCCGGCTGGCAGACCCGCCCCATGCAGACCTCCGACGCCCCCTCCCCCC
TCACGGTGCGCGACGTGGTGGAACGGCACGGCGGAGAATTGTGGCTGGAGCATGCGCGCGACGGCTCGGGGGCCCTGTTC
CGCTTCCTGCTGCCGGTGGCCGCCGGCACGGTGGCGCCGGTGCCGGCCCCCGGCGACAGCCGCCCGGCCTATTATGATTT
CGACCTGTTCGCCGCGAGCGCGCAGAGCCGCGAGAGCGACGACCGTCCGCTGGGCGAGATCGCCTATACGGTGTTCGACA
CCGAGACCACCGGCCTTGATCCCGCCGGCGGCGACGAAATCCTCCAGATCGGCGCCACCCGCATCGTCAACGGCCGGCTG
CTCGCCAGCGAATGCTTCGACCAATTGGTGGACCCGCAGCGCTCCATCCCGGAGGCCGGCATCGCGGTGCACGGCATCCG
GCCGGAGATGGTGCGCGGCAAGCCGACCCTTCCCCAGGTGCTCCCCGCCTTCCACGCCTTCGCCGCCGACACCGTTCTGG
TGGGCCACAACGTGGCCTTCGACATGCGCTTTTTGACCCTCAAGGAAAACGCCAGCGGCGTGCGCTTCGACCAGCCGGTG
CTCGACACCCTGTTGCTCGCCGCCATCGTCCATCCCGGGGAGGACAGCCACGGACTGGAGGCCATGGCGGCGCGCCTCGG
CATCGCCGTCTCCGGCCGCCACACGGCACTGGGGGACGCGCTGGCCACCGCCGAGATCTTCCTGAAGCTGCTGCCGCTGC
TGCGCCAGCGCGGCATCGTCACCCTCGGGCAGGCCCGCGCGGCGGCGCAGACCTCCTATTACGCGCGCCTGCGCTATTGA

Upstream 100 bases:

>100_bases
TGGTACAGCAGGTGAAGGACATGCTGGCCCGGGATTCGGCCGCAGGGGCCGTGGCGGCGAGCAGCGCCGCGGCGGGCGAA
ATGCCGAAGGACCTGCCGGC

Downstream 100 bases:

>100_bases
GTCCAAGGGATCCGACCGTCGGCCGGCGCGCACGGGGTGTTGCCGCAATTCCCCCGTCATGCCCGGGCTTGTCCCGGCCA
TCCACGCCTGACCACCTGGG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 719; Mature: 718

Protein sequence:

>719_residues
MSFDRRLALIVLAPGALLGLWLLGGAGLLYAALGPADRAAITDTVAPLIDSHGMLVVLWWFLAALGTGVVALRLHAIYGE
APARLADATRVLAGDAAAPPLPPQSGTGMRALGEAINALAGQRRALQDDMARLIAEASRDVALQRDQLAALMAELEQSVV
VLNLEGRILLYNARARALFRTLSQAPGGVAGAELIGLGRSIHAVIDRALIDHAREGIARRIARGDAQASARFVTTTPLGH
LIQVSLAPVRAAADDKGDVTGFVLLLDDITDEYEARSRQDRRWLDLSEASRASFASMQAALDMLDYPDLEPADRERFQAV
VRDEVGVMSQRLTTLAADASHDMKTRWPLQDMLGADLAAAAAQRITAETGQAVDTVAVDADLWLSVDSFALIQALAFLAA
RLSETLKAPNLALRLAPAGGRAHLDLAFQGTGSGLDLAGWQTRPMQTSDAPSPLTVRDVVERHGGELWLEHARDGSGALF
RFLLPVAAGTVAPVPAPGDSRPAYYDFDLFAASAQSRESDDRPLGEIAYTVFDTETTGLDPAGGDEILQIGATRIVNGRL
LASECFDQLVDPQRSIPEAGIAVHGIRPEMVRGKPTLPQVLPAFHAFAADTVLVGHNVAFDMRFLTLKENASGVRFDQPV
LDTLLLAAIVHPGEDSHGLEAMAARLGIAVSGRHTALGDALATAEIFLKLLPLLRQRGIVTLGQARAAAQTSYYARLRY

Sequences:

>Translated_719_residues
MSFDRRLALIVLAPGALLGLWLLGGAGLLYAALGPADRAAITDTVAPLIDSHGMLVVLWWFLAALGTGVVALRLHAIYGE
APARLADATRVLAGDAAAPPLPPQSGTGMRALGEAINALAGQRRALQDDMARLIAEASRDVALQRDQLAALMAELEQSVV
VLNLEGRILLYNARARALFRTLSQAPGGVAGAELIGLGRSIHAVIDRALIDHAREGIARRIARGDAQASARFVTTTPLGH
LIQVSLAPVRAAADDKGDVTGFVLLLDDITDEYEARSRQDRRWLDLSEASRASFASMQAALDMLDYPDLEPADRERFQAV
VRDEVGVMSQRLTTLAADASHDMKTRWPLQDMLGADLAAAAAQRITAETGQAVDTVAVDADLWLSVDSFALIQALAFLAA
RLSETLKAPNLALRLAPAGGRAHLDLAFQGTGSGLDLAGWQTRPMQTSDAPSPLTVRDVVERHGGELWLEHARDGSGALF
RFLLPVAAGTVAPVPAPGDSRPAYYDFDLFAASAQSRESDDRPLGEIAYTVFDTETTGLDPAGGDEILQIGATRIVNGRL
LASECFDQLVDPQRSIPEAGIAVHGIRPEMVRGKPTLPQVLPAFHAFAADTVLVGHNVAFDMRFLTLKENASGVRFDQPV
LDTLLLAAIVHPGEDSHGLEAMAARLGIAVSGRHTALGDALATAEIFLKLLPLLRQRGIVTLGQARAAAQTSYYARLRY
>Mature_718_residues
SFDRRLALIVLAPGALLGLWLLGGAGLLYAALGPADRAAITDTVAPLIDSHGMLVVLWWFLAALGTGVVALRLHAIYGEA
PARLADATRVLAGDAAAPPLPPQSGTGMRALGEAINALAGQRRALQDDMARLIAEASRDVALQRDQLAALMAELEQSVVV
LNLEGRILLYNARARALFRTLSQAPGGVAGAELIGLGRSIHAVIDRALIDHAREGIARRIARGDAQASARFVTTTPLGHL
IQVSLAPVRAAADDKGDVTGFVLLLDDITDEYEARSRQDRRWLDLSEASRASFASMQAALDMLDYPDLEPADRERFQAVV
RDEVGVMSQRLTTLAADASHDMKTRWPLQDMLGADLAAAAAQRITAETGQAVDTVAVDADLWLSVDSFALIQALAFLAAR
LSETLKAPNLALRLAPAGGRAHLDLAFQGTGSGLDLAGWQTRPMQTSDAPSPLTVRDVVERHGGELWLEHARDGSGALFR
FLLPVAAGTVAPVPAPGDSRPAYYDFDLFAASAQSRESDDRPLGEIAYTVFDTETTGLDPAGGDEILQIGATRIVNGRLL
ASECFDQLVDPQRSIPEAGIAVHGIRPEMVRGKPTLPQVLPAFHAFAADTVLVGHNVAFDMRFLTLKENASGVRFDQPVL
DTLLLAAIVHPGEDSHGLEAMAARLGIAVSGRHTALGDALATAEIFLKLLPLLRQRGIVTLGQARAAAQTSYYARLRY

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG2176

COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786409, Length=171, Percent_Identity=35.672514619883, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR000014
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 76575; Mature: 76444

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDRRLALIVLAPGALLGLWLLGGAGLLYAALGPADRAAITDTVAPLIDSHGMLVVLWW
CCCCCEEEEEEECCHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHH
FLAALGTGVVALRLHAIYGEAPARLADATRVLAGDAAAPPLPPQSGTGMRALGEAINALA
HHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
GQRRALQDDMARLIAEASRDVALQRDQLAALMAELEQSVVVLNLEGRILLYNARARALFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEHHHHHHHH
TLSQAPGGVAGAELIGLGRSIHAVIDRALIDHAREGIARRIARGDAQASARFVTTTPLGH
HHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCEEEEECCCCH
LIQVSLAPVRAAADDKGDVTGFVLLLDDITDEYEARSRQDRRWLDLSEASRASFASMQAA
HHEEEHHHHHHCCCCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LDMLDYPDLEPADRERFQAVVRDEVGVMSQRLTTLAADASHDMKTRWPLQDMLGADLAAA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHH
AAQRITAETGQAVDTVAVDADLWLSVDSFALIQALAFLAARLSETLKAPNLALRLAPAGG
HHHHHHHHCCCCEEEEEECCHHEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
RAHLDLAFQGTGSGLDLAGWQTRPMQTSDAPSPLTVRDVVERHGGELWLEHARDGSGALF
CEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEHHCCCCCHHHH
RFLLPVAAGTVAPVPAPGDSRPAYYDFDLFAASAQSRESDDRPLGEIAYTVFDTETTGLD
HHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCHHHEEEEEEECCCCCCC
PAGGDEILQIGATRIVNGRLLASECFDQLVDPQRSIPEAGIAVHGIRPEMVRGKPTLPQV
CCCCHHHHHHCCHHHCCCEEHHHHHHHHHCCCHHCCCCCCEEEECCCHHHHCCCCCHHHH
LPAFHAFAADTVLVGHNVAFDMRFLTLKENASGVRFDQPVLDTLLLAAIVHPGEDSHGLE
HHHHHHHHHCEEEEECCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHH
AMAARLGIAVSGRHTALGDALATAEIFLKLLPLLRQRGIVTLGQARAAAQTSYYARLRY
HHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHEEEECC
>Mature Secondary Structure 
SFDRRLALIVLAPGALLGLWLLGGAGLLYAALGPADRAAITDTVAPLIDSHGMLVVLWW
CCCCEEEEEEECCHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHH
FLAALGTGVVALRLHAIYGEAPARLADATRVLAGDAAAPPLPPQSGTGMRALGEAINALA
HHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
GQRRALQDDMARLIAEASRDVALQRDQLAALMAELEQSVVVLNLEGRILLYNARARALFR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEEHHHHHHHH
TLSQAPGGVAGAELIGLGRSIHAVIDRALIDHAREGIARRIARGDAQASARFVTTTPLGH
HHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCEEEEECCCCH
LIQVSLAPVRAAADDKGDVTGFVLLLDDITDEYEARSRQDRRWLDLSEASRASFASMQAA
HHEEEHHHHHHCCCCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
LDMLDYPDLEPADRERFQAVVRDEVGVMSQRLTTLAADASHDMKTRWPLQDMLGADLAAA
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCHHHHH
AAQRITAETGQAVDTVAVDADLWLSVDSFALIQALAFLAARLSETLKAPNLALRLAPAGG
HHHHHHHHCCCCEEEEEECCHHEEECHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
RAHLDLAFQGTGSGLDLAGWQTRPMQTSDAPSPLTVRDVVERHGGELWLEHARDGSGALF
CEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCEEEHHCCCCCHHHH
RFLLPVAAGTVAPVPAPGDSRPAYYDFDLFAASAQSRESDDRPLGEIAYTVFDTETTGLD
HHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCCCCHHHEEEEEEECCCCCCC
PAGGDEILQIGATRIVNGRLLASECFDQLVDPQRSIPEAGIAVHGIRPEMVRGKPTLPQV
CCCCHHHHHHCCHHHCCCEEHHHHHHHHHCCCHHCCCCCCEEEECCCHHHHCCCCCHHHH
LPAFHAFAADTVLVGHNVAFDMRFLTLKENASGVRFDQPVLDTLLLAAIVHPGEDSHGLE
HHHHHHHHHCEEEEECCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHH
AMAARLGIAVSGRHTALGDALATAEIFLKLLPLLRQRGIVTLGQARAAAQTSYYARLRY
HHHHHHCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]