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The map label for this gene is pncB [H]

Identifier: 154246307

GI number: 154246307

Start: 2639987

End: 2641279

Strand: Reverse

Name: pncB [H]

Synonym: Xaut_2365

Alternate gene names: 154246307

Gene position: 2641279-2639987 (Counterclockwise)

Preceding gene: 154246308

Following gene: 154246305

Centisome position: 49.75

GC content: 67.67

Gene sequence:

>1293_bases
ATGACCGACATCGCCACGCGCGTCTACAACCACACCTGGAAGATCGACCCCATCGTGCGGTCCGTGCTCGACACGGACTT
CTACAAGCTGCTGATGGGGCAGACGATCTTCCACCGGCACCGGTCGACGCAAGTCACCTTCGGCATCCACAACCGCTCCA
CCGCCATCCGCCTCGCCGAGATCATCGACGTGGGCGCCCTGCGCGAGCAGCTCGACCATGTGCGCTCCCTCAGGCTCACC
CGGGGCGAGAGCACGTGGCTGCGCGGCAACATGTTCTACGGCAAGCGGCAGATGTTCTCGCCGGACTATGTGGCGTGGCT
GGAGGGCTTCCGCTTCCCGGCCTATCACCTGGAAAAGCGCGACGGCCAGTATGAACTGACCTTCGAGGGGCCGTGGGTCG
AAACCACCATGTGGGAGATCCCGGCGCTCGCCATCATCAACGAACTGCGCTCGCGCGCGGTGCTGAAGGGCATGGGCAAG
TTCGAGCTGCAGATCCTCTATGCCCGGGCCATGGCGCGGGTGTGGGAGAAGGTGCAGTTCCTCAAAACCCTCGCCCCCAT
CAACATCGCCGATTTCGGCACCCGCCGGCGCCACGGCTTCCTGTGGCAGGACTGGTGCGTCCAGTCCCTCATCGAGGGGC
TGGGCGAGGGCTTCCTCGGCACCTCCAACTGCCTCATCGCCATGCGGCGCGAGGTGGAGGCCACCGGCACCAACGCCCAC
GAGCTGCCCATGGTCTATGCGGCGCTGGCCCGCAACGACGAGGAGCTGGCCTGGGCGCCCTACCAGGTGCTGGCCGACTG
GCAGGAGGATTACGACGGCAACCTGCGCGTCATCCTGCCCGACACCTACGGCACCAGCGGCTTCCTGAAGCGCGCCCCCG
ACTGGGTGGCGCACTGGACCGGCATCCGCATCGACAGCAAGGACCCGGTGGAGGGCGGCGAGGAAGCCCTCGCCTGGTGG
CAGGCGCGGGGCCAGGACCCGCGCGAGAAGCTCGCCATCTTCTCCGATGCCCTCGATGCCGAGGAAGTGGCGCGCATCCA
CCGCACCTTCATCGGGCGCATGCGGCTCGGCTTCGGCTGGGGCACGCTGCTCACCAACGATTTCCGCGGCCTTGCGCCCC
ACGGCGCGCTCGACCCCATCTCCATCGTCTGCAAGGTGGTCTCGGCCAACGGCCGCCCCGCGGTGAAGCTCTCCGACAAC
CCCACCAAGGCCATGGGCCCGGCGGAGGAGATCGAGCGCTACAAGCGGGTGTTCGAGGTGGGCGAGCAGGTGGCGCGCCA
CGCCCTGGTCTGA

Upstream 100 bases:

>100_bases
AACGGATCGCATTCAGCGCCGACATGCTATAGGTGGTGCGCCTGCCCTGCGGACGCGCCCCTGACCGGACGCCGCCCCTT
CCAACACCCGCAAGACGCCA

Downstream 100 bases:

>100_bases
GAGGCCGAGGGGCCGGCGGCCTGAGGGGCTGCGCGCCGGCCCGCCGGTTCAGTTCCGGAGCGCGGCCGTCCCGTCCACCG
CGGCCGGAAACGGCAGGTCC

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MTDIATRVYNHTWKIDPIVRSVLDTDFYKLLMGQTIFHRHRSTQVTFGIHNRSTAIRLAEIIDVGALREQLDHVRSLRLT
RGESTWLRGNMFYGKRQMFSPDYVAWLEGFRFPAYHLEKRDGQYELTFEGPWVETTMWEIPALAIINELRSRAVLKGMGK
FELQILYARAMARVWEKVQFLKTLAPINIADFGTRRRHGFLWQDWCVQSLIEGLGEGFLGTSNCLIAMRREVEATGTNAH
ELPMVYAALARNDEELAWAPYQVLADWQEDYDGNLRVILPDTYGTSGFLKRAPDWVAHWTGIRIDSKDPVEGGEEALAWW
QARGQDPREKLAIFSDALDAEEVARIHRTFIGRMRLGFGWGTLLTNDFRGLAPHGALDPISIVCKVVSANGRPAVKLSDN
PTKAMGPAEEIERYKRVFEVGEQVARHALV

Sequences:

>Translated_430_residues
MTDIATRVYNHTWKIDPIVRSVLDTDFYKLLMGQTIFHRHRSTQVTFGIHNRSTAIRLAEIIDVGALREQLDHVRSLRLT
RGESTWLRGNMFYGKRQMFSPDYVAWLEGFRFPAYHLEKRDGQYELTFEGPWVETTMWEIPALAIINELRSRAVLKGMGK
FELQILYARAMARVWEKVQFLKTLAPINIADFGTRRRHGFLWQDWCVQSLIEGLGEGFLGTSNCLIAMRREVEATGTNAH
ELPMVYAALARNDEELAWAPYQVLADWQEDYDGNLRVILPDTYGTSGFLKRAPDWVAHWTGIRIDSKDPVEGGEEALAWW
QARGQDPREKLAIFSDALDAEEVARIHRTFIGRMRLGFGWGTLLTNDFRGLAPHGALDPISIVCKVVSANGRPAVKLSDN
PTKAMGPAEEIERYKRVFEVGEQVARHALV
>Mature_429_residues
TDIATRVYNHTWKIDPIVRSVLDTDFYKLLMGQTIFHRHRSTQVTFGIHNRSTAIRLAEIIDVGALREQLDHVRSLRLTR
GESTWLRGNMFYGKRQMFSPDYVAWLEGFRFPAYHLEKRDGQYELTFEGPWVETTMWEIPALAIINELRSRAVLKGMGKF
ELQILYARAMARVWEKVQFLKTLAPINIADFGTRRRHGFLWQDWCVQSLIEGLGEGFLGTSNCLIAMRREVEATGTNAHE
LPMVYAALARNDEELAWAPYQVLADWQEDYDGNLRVILPDTYGTSGFLKRAPDWVAHWTGIRIDSKDPVEGGEEALAWWQ
ARGQDPREKLAIFSDALDAEEVARIHRTFIGRMRLGFGWGTLLTNDFRGLAPHGALDPISIVCKVVSANGRPAVKLSDNP
TKAMGPAEEIERYKRVFEVGEQVARHALV

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=398, Percent_Identity=33.4170854271357, Blast_Score=197, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324783, Length=424, Percent_Identity=29.0094339622642, Blast_Score=160, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 49163; Mature: 49032

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIATRVYNHTWKIDPIVRSVLDTDFYKLLMGQTIFHRHRSTQVTFGIHNRSTAIRLAE
CCCHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
IIDVGALREQLDHVRSLRLTRGESTWLRGNMFYGKRQMFSPDYVAWLEGFRFPAYHLEKR
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEECCHHCCCCHHHHHHHCCCCCHHHHHCC
DGQYELTFEGPWVETTMWEIPALAIINELRSRAVLKGMGKFELQILYARAMARVWEKVQF
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LKTLAPINIADFGTRRRHGFLWQDWCVQSLIEGLGEGFLGTSNCLIAMRREVEATGTNAH
HHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCH
ELPMVYAALARNDEELAWAPYQVLADWQEDYDGNLRVILPDTYGTSGFLKRAPDWVAHWT
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCHHHHHHC
GIRIDSKDPVEGGEEALAWWQARGQDPREKLAIFSDALDAEEVARIHRTFIGRMRLGFGW
CEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
GTLLTNDFRGLAPHGALDPISIVCKVVSANGRPAVKLSDNPTKAMGPAEEIERYKRVFEV
HHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
GEQVARHALV
HHHHHHHCCC
>Mature Secondary Structure 
TDIATRVYNHTWKIDPIVRSVLDTDFYKLLMGQTIFHRHRSTQVTFGIHNRSTAIRLAE
CCHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
IIDVGALREQLDHVRSLRLTRGESTWLRGNMFYGKRQMFSPDYVAWLEGFRFPAYHLEKR
HHHHHHHHHHHHHHHHHHHCCCCCCEEECCEEECCHHCCCCHHHHHHHCCCCCHHHHHCC
DGQYELTFEGPWVETTMWEIPALAIINELRSRAVLKGMGKFELQILYARAMARVWEKVQF
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
LKTLAPINIADFGTRRRHGFLWQDWCVQSLIEGLGEGFLGTSNCLIAMRREVEATGTNAH
HHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCH
ELPMVYAALARNDEELAWAPYQVLADWQEDYDGNLRVILPDTYGTSGFLKRAPDWVAHWT
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHCCCHHHHHHC
GIRIDSKDPVEGGEEALAWWQARGQDPREKLAIFSDALDAEEVARIHRTFIGRMRLGFGW
CEEECCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCH
GTLLTNDFRGLAPHGALDPISIVCKVVSANGRPAVKLSDNPTKAMGPAEEIERYKRVFEV
HHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHH
GEQVARHALV
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]