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The map label for this gene is ahpC [C]

Identifier: 154246305

GI number: 154246305

Start: 2637921

End: 2638559

Strand: Reverse

Name: ahpC [C]

Synonym: Xaut_2363

Alternate gene names: 154246305

Gene position: 2638559-2637921 (Counterclockwise)

Preceding gene: 154246307

Following gene: 154246300

Centisome position: 49.7

GC content: 65.1

Gene sequence:

>639_bases
ATGGCGACCCTGCGACTTGGCGACGTGGTGCCCGATTTCGAGGCCGTGACCACTGAAGGCCCCATCAAGTTTCATGAGTG
GCTCGGCGACAGCTGGGGCATCCTGTTTTCCCACCCCAAGAACTTCACCCCCGTCTGCACCACCGAGCTCGGCCAGGCGT
CCCACCTGAAGCCCGAGTTCGACAAGCGCGGCGTGAAGCTGATCGGCCTGTCGGTGGACACCATCGAGAACCACCCGGCC
TGGGTGGGCGACATCAAGGACGCCACCGGCGCCAGCCTCAACTTCCCGCTGATCGCCGACTCGGACAAGAAGGTCTCCGA
CCTCTACGACCTGATCCACCCCAACGCGAGCGACACCGCCACCGTGCGCTCGGTGTTCATCATCGGGCCGGACAAGAAGC
TGAAGCTGTCCCTGACCTATCCGGCCTCCACCGGCCGCAACTTCGACGAGATCCTGCGCGTGGTGGACAGCCTCCAGCTC
ACCGCCAAGCATTCGGTCGCGACCCCGGTGAACTGGAAGCACGGCGAGGACGTGATCATCGTCCCCTCCGTCACCGACGA
GGCGGCCAAGGAGAAGTTCCCCGAAGGCTGGAAGACCGTGAAGCCCTATCTGCGCGTGGTGCGCCAGCCGGGCGCCTGA

Upstream 100 bases:

>100_bases
CAGGCTAGGTGATTCAGACGATGTGATTCACCTTTAAATGCATAAAACTTGTAGTATAATGAAGTTATATACAGTTTTTC
GATGTTTATTGGAGAAGATC

Downstream 100 bases:

>100_bases
GCCCACGGGCCATGCGCCCACGAGCCATATGCGGCGGGACACATCCCGCCGCATGCGTCCCGGCCGGCTCATGCCGGCCG
GTTTCGTTTCAGGCTTTGGG

Product: peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MATLRLGDVVPDFEAVTTEGPIKFHEWLGDSWGILFSHPKNFTPVCTTELGQASHLKPEFDKRGVKLIGLSVDTIENHPA
WVGDIKDATGASLNFPLIADSDKKVSDLYDLIHPNASDTATVRSVFIIGPDKKLKLSLTYPASTGRNFDEILRVVDSLQL
TAKHSVATPVNWKHGEDVIIVPSVTDEAAKEKFPEGWKTVKPYLRVVRQPGA

Sequences:

>Translated_212_residues
MATLRLGDVVPDFEAVTTEGPIKFHEWLGDSWGILFSHPKNFTPVCTTELGQASHLKPEFDKRGVKLIGLSVDTIENHPA
WVGDIKDATGASLNFPLIADSDKKVSDLYDLIHPNASDTATVRSVFIIGPDKKLKLSLTYPASTGRNFDEILRVVDSLQL
TAKHSVATPVNWKHGEDVIIVPSVTDEAAKEKFPEGWKTVKPYLRVVRQPGA
>Mature_211_residues
ATLRLGDVVPDFEAVTTEGPIKFHEWLGDSWGILFSHPKNFTPVCTTELGQASHLKPEFDKRGVKLIGLSVDTIENHPAW
VGDIKDATGASLNFPLIADSDKKVSDLYDLIHPNASDTATVRSVFIIGPDKKLKLSLTYPASTGRNFDEILRVVDSLQLT
AKHSVATPVNWKHGEDVIIVPSVTDEAAKEKFPEGWKTVKPYLRVVRQPGA

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=220, Percent_Identity=55.4545454545455, Blast_Score=236, Evalue=1e-62,
Organism=Homo sapiens, GI32189392, Length=194, Percent_Identity=33.5051546391753, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI4505591, Length=180, Percent_Identity=32.7777777777778, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI32455266, Length=180, Percent_Identity=32.7777777777778, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI32455264, Length=180, Percent_Identity=32.7777777777778, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI5453549, Length=161, Percent_Identity=30.4347826086957, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI32483377, Length=140, Percent_Identity=30, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI5802974, Length=140, Percent_Identity=30, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=27.9220779220779, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI25153706, Length=226, Percent_Identity=41.5929203539823, Blast_Score=171, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17554494, Length=163, Percent_Identity=30.6748466257669, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI193204376, Length=149, Percent_Identity=30.2013422818792, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI32565831, Length=149, Percent_Identity=30.2013422818792, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=51.4150943396226, Blast_Score=223, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6323613, Length=156, Percent_Identity=31.4102564102564, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=156, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24581278, Length=217, Percent_Identity=48.3870967741936, Blast_Score=214, Evalue=3e-56,
Organism=Drosophila melanogaster, GI24652434, Length=205, Percent_Identity=49.7560975609756, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24652436, Length=205, Percent_Identity=49.7560975609756, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI17975518, Length=205, Percent_Identity=49.7560975609756, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=29.9435028248588, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17157991, Length=160, Percent_Identity=31.875, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641739, Length=160, Percent_Identity=31.875, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357347, Length=197, Percent_Identity=28.4263959390863, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24656348, Length=175, Percent_Identity=32, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17864676, Length=175, Percent_Identity=32, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 23325; Mature: 23194

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLRLGDVVPDFEAVTTEGPIKFHEWLGDSWGILFSHPKNFTPVCTTELGQASHLKPEF
CCEEECCCCCCCCHHCCCCCCCHHHHHCCCCCCEEEECCCCCCCEECCCCCCCCCCCCCC
DKRGVKLIGLSVDTIENHPAWVGDIKDATGASLNFPLIADSDKKVSDLYDLIHPNASDTA
CCCCEEEEEEEEECCCCCCCEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCE
TVRSVFIIGPDKKLKLSLTYPASTGRNFDEILRVVDSLQLTAKHSVATPVNWKHGEDVII
EEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
VPSVTDEAAKEKFPEGWKTVKPYLRVVRQPGA
EECCCCHHHHHHCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ATLRLGDVVPDFEAVTTEGPIKFHEWLGDSWGILFSHPKNFTPVCTTELGQASHLKPEF
CEEECCCCCCCCHHCCCCCCCHHHHHCCCCCCEEEECCCCCCCEECCCCCCCCCCCCCC
DKRGVKLIGLSVDTIENHPAWVGDIKDATGASLNFPLIADSDKKVSDLYDLIHPNASDTA
CCCCEEEEEEEEECCCCCCCEEECCCCCCCCCCCCCEEECCCCHHHHHHHHHCCCCCCCE
TVRSVFIIGPDKKLKLSLTYPASTGRNFDEILRVVDSLQLTAKHSVATPVNWKHGEDVII
EEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
VPSVTDEAAKEKFPEGWKTVKPYLRVVRQPGA
EECCCCHHHHHHCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]