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The map label for this gene is yccK [H]

Identifier: 154246272

GI number: 154246272

Start: 2603146

End: 2604132

Strand: Direct

Name: yccK [H]

Synonym: Xaut_2330

Alternate gene names: 154246272

Gene position: 2603146-2604132 (Clockwise)

Preceding gene: 154246266

Following gene: 154246273

Centisome position: 49.03

GC content: 66.97

Gene sequence:

>987_bases
ATGGACCACCGTCCTCTCGGTCGCTCGGGTCTTTCCGTGTCCGCCATCGGCCTCGGCTGCATGGGCATGTCCGAATTCTA
CGGCCCCAGCGATGACGAGCAGTCGCTCGCAACCCTAGCAGCGGCCCTCGATCTGGGCATGAATTTCTTCGATACCGCTG
ACATGTACGGCGTCGGCCACAATGAGCGGCTGCTCGGGCGCTTCCTAAAGGGCCGGCGCGATCAGGTGATCCTCGCCACC
AAGTTCGGCAATGTGCGCGGGCCAAACGGCGAGCGCCTGGGCGTTTGCGGCACGCCGGACTATGTGCGCACCGCCTGCGA
CGCCAGCCTCGGGCGTCTCGGCATCGACACCATCGACCTTTATTACCAGCACCGCGTGGACCCCAAAACGCCCATCGAGG
ACACCGTGGGCGCCATGAAGGGGCTGGTGGAGGCGGGCAAGGTGCGCTTCCTCGGCCTGTCGGAATGCTCGGTGGAGACG
CTGCGGCGCGCCCACAAGGTGCATCCCATCAGCGCGGTGCAGATCGAATATTCGCTGTGGAGCCGGGATCCGGAGGCCGG
GATGCTGGACGCCTGCCGCGAGCTGGGCATCGCCTTCGTTGCCTACAGCCCGCTCGGGCGCTCCTTCCTCACCGGTGCGG
TGACCAGCCCCGACAGCCTCGCGCCGGATGATTTCCGTCGCGCCAATCCTCGCTTCTCAGGGGCGGCGCTGGCGCAGAAC
CTCAAGCTCACCGAAGCGTTGAAGGACTTCGCGGAGACCAAGGGCGCCACCAGCGCCCAGATCGCTCTGGCCTGGATCCT
GAACAAGCAGGAGCATGTGGTCCCCATCCCCGGCACCCGGCGCATCAAGTACCTGCAGGAGAACGCGGCGGCGACCGTCA
TCCGCCTGACGCCGCAGGAGATCGCCAGCCTCGACGCCCTGTTCGCTCCGGACGCGGTGGCAGGCACGCGCTATCCTGAG
GCCGGCATGGCGCAGCTCGGCCTGTGA

Upstream 100 bases:

>100_bases
GACGGGTCATTGACAAAAGTAAACGGTACGGTGTAGTTTACATAAACGGCCAGCGCCTGTCGCGCCGCCTGCTATTCCTC
TCATAGTCATGAGGTCCCCC

Downstream 100 bases:

>100_bases
CGGGCGAGGGGCGGCGCCGGTGGGTGCCGCCCCCTGTCTCCATCCACAGGGGATGGACCTGCCGCAAGGGCGGTTCACAT
CCCAAATTTCACATGCTATG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MDHRPLGRSGLSVSAIGLGCMGMSEFYGPSDDEQSLATLAAALDLGMNFFDTADMYGVGHNERLLGRFLKGRRDQVILAT
KFGNVRGPNGERLGVCGTPDYVRTACDASLGRLGIDTIDLYYQHRVDPKTPIEDTVGAMKGLVEAGKVRFLGLSECSVET
LRRAHKVHPISAVQIEYSLWSRDPEAGMLDACRELGIAFVAYSPLGRSFLTGAVTSPDSLAPDDFRRANPRFSGAALAQN
LKLTEALKDFAETKGATSAQIALAWILNKQEHVVPIPGTRRIKYLQENAAATVIRLTPQEIASLDALFAPDAVAGTRYPE
AGMAQLGL

Sequences:

>Translated_328_residues
MDHRPLGRSGLSVSAIGLGCMGMSEFYGPSDDEQSLATLAAALDLGMNFFDTADMYGVGHNERLLGRFLKGRRDQVILAT
KFGNVRGPNGERLGVCGTPDYVRTACDASLGRLGIDTIDLYYQHRVDPKTPIEDTVGAMKGLVEAGKVRFLGLSECSVET
LRRAHKVHPISAVQIEYSLWSRDPEAGMLDACRELGIAFVAYSPLGRSFLTGAVTSPDSLAPDDFRRANPRFSGAALAQN
LKLTEALKDFAETKGATSAQIALAWILNKQEHVVPIPGTRRIKYLQENAAATVIRLTPQEIASLDALFAPDAVAGTRYPE
AGMAQLGL
>Mature_328_residues
MDHRPLGRSGLSVSAIGLGCMGMSEFYGPSDDEQSLATLAAALDLGMNFFDTADMYGVGHNERLLGRFLKGRRDQVILAT
KFGNVRGPNGERLGVCGTPDYVRTACDASLGRLGIDTIDLYYQHRVDPKTPIEDTVGAMKGLVEAGKVRFLGLSECSVET
LRRAHKVHPISAVQIEYSLWSRDPEAGMLDACRELGIAFVAYSPLGRSFLTGAVTSPDSLAPDDFRRANPRFSGAALAQN
LKLTEALKDFAETKGATSAQIALAWILNKQEHVVPIPGTRRIKYLQENAAATVIRLTPQEIASLDALFAPDAVAGTRYPE
AGMAQLGL

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=329, Percent_Identity=29.7872340425532, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI4504825, Length=327, Percent_Identity=29.6636085626911, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI27436971, Length=328, Percent_Identity=28.3536585365854, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI27436966, Length=325, Percent_Identity=28, Blast_Score=105, Evalue=6e-23,
Organism=Homo sapiens, GI27436964, Length=325, Percent_Identity=27.6923076923077, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI27436962, Length=325, Percent_Identity=27.6923076923077, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI223718702, Length=218, Percent_Identity=31.1926605504587, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI41327764, Length=293, Percent_Identity=27.6450511945392, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI87081735, Length=333, Percent_Identity=35.4354354354354, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=31.6109422492401, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788070, Length=312, Percent_Identity=30.7692307692308, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1787674, Length=310, Percent_Identity=29.3548387096774, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788081, Length=314, Percent_Identity=28.343949044586, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=28.5302593659942, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI48994888, Length=277, Percent_Identity=25.6317689530686, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319958, Length=304, Percent_Identity=29.6052631578947, Blast_Score=122, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6323998, Length=328, Percent_Identity=29.5731707317073, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=26.4094955489614, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6325384, Length=336, Percent_Identity=25.5952380952381, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6322615, Length=255, Percent_Identity=29.4117647058824, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6319951, Length=310, Percent_Identity=27.0967741935484, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646159, Length=236, Percent_Identity=29.2372881355932, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24646155, Length=167, Percent_Identity=31.1377245508982, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24640980, Length=301, Percent_Identity=24.2524916943522, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI45549126, Length=301, Percent_Identity=24.2524916943522, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 35356; Mature: 35356

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHRPLGRSGLSVSAIGLGCMGMSEFYGPSDDEQSLATLAAALDLGMNFFDTADMYGVGH
CCCCCCCCCCCEEEEHEECCCCHHHHCCCCCCHHHHHHHHHHHHHCCCHHCCCHHHCCCC
NERLLGRFLKGRRDQVILATKFGNVRGPNGERLGVCGTPDYVRTACDASLGRLGIDTIDL
CHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHEEH
YYQHRVDPKTPIEDTVGAMKGLVEAGKVRFLGLSECSVETLRRAHKVHPISAVQIEYSLW
HHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCEEEEEEEHHH
SRDPEAGMLDACRELGIAFVAYSPLGRSFLTGAVTSPDSLAPDDFRRANPRFSGAALAQN
CCCCCCCHHHHHHHCCEEEEEECCCCHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHC
LKLTEALKDFAETKGATSAQIALAWILNKQEHVVPIPGTRRIKYLQENAAATVIRLTPQE
CHHHHHHHHHHHHCCCCHHHEEEEEEECCCCCEEECCCCHHHHHHHHCCCEEEEEECHHH
IASLDALFAPDAVAGTRYPEAGMAQLGL
HHHHHHHHCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MDHRPLGRSGLSVSAIGLGCMGMSEFYGPSDDEQSLATLAAALDLGMNFFDTADMYGVGH
CCCCCCCCCCCEEEEHEECCCCHHHHCCCCCCHHHHHHHHHHHHHCCCHHCCCHHHCCCC
NERLLGRFLKGRRDQVILATKFGNVRGPNGERLGVCGTPDYVRTACDASLGRLGIDTIDL
CHHHHHHHHCCCCCCEEEEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCHHEEH
YYQHRVDPKTPIEDTVGAMKGLVEAGKVRFLGLSECSVETLRRAHKVHPISAVQIEYSLW
HHHHCCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCCEEEEEEEHHH
SRDPEAGMLDACRELGIAFVAYSPLGRSFLTGAVTSPDSLAPDDFRRANPRFSGAALAQN
CCCCCCCHHHHHHHCCEEEEEECCCCHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHC
LKLTEALKDFAETKGATSAQIALAWILNKQEHVVPIPGTRRIKYLQENAAATVIRLTPQE
CHHHHHHHHHHHHCCCCHHHEEEEEEECCCCCEEECCCCHHHHHHHHCCCEEEEEECHHH
IASLDALFAPDAVAGTRYPEAGMAQLGL
HHHHHHHHCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]