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The map label for this gene is ygjG [C]

Identifier: 154246241

GI number: 154246241

Start: 2564991

End: 2566352

Strand: Direct

Name: ygjG [C]

Synonym: Xaut_2299

Alternate gene names: 154246241

Gene position: 2564991-2566352 (Clockwise)

Preceding gene: 154246238

Following gene: 154246247

Centisome position: 48.31

GC content: 67.11

Gene sequence:

>1362_bases
ATGGCTCTGGACGATCTGGTTACCGAAGGCGCGGGCGTGGGTGCGGACGCGATTCCCAACGATCTCGACGCTTTCTGGAT
GCCGTTCACCTCCAACCGTTCGTTCAAGAAGCGACCGCGGCTCGTCTCCCGGGCCAAGGACATGCACTATTACACTCCGG
AAGGTCGCGCCATTCTCGACGGCTGCGCCGGGCTGTGGTGCGTCAATCCTGGCCATAACCGCGAGCCCATCGTGGAGGCC
ATCCGCCAGGCCGCCACCGAGGTGGATTTCGCCCCCACCTTCCAGTACGGCCACCCCCAGGCGTTTCGCCTCGCCAGCCG
CATCGCGGACCTCGCGCCGGGCGATCTCGACCACGTGTTCTTCTGCAATTCCGGCTCGGAGGCGGTGGACACCGCGCTGA
AGATCGCGCTCGCCTACCACCAGACCACGGGCGCCGGCACCCGCACCCGCCTCATCGGCCGCGAGCGCGGCTATCACGGG
GTGGGCTTCGGCGGCATCTCGGTGGGCGGCATCGTGTCGAATCGCCGGACCTTCGGCACCATGCTCACCGGCGTCGATCA
CCTGCGCTCGACCTATGACCGGGAGCATCAGGCCTTCACCAAGGGTGAGCCGGACTACGGCGCGCACTTCGCCGATGAGC
TGGAGCGCATCGTTGCCCTGCACGATGCCTCCACCATCGCCTCGGTGATCGTGGAGCCCATGGGCGGCTCCACCGGCGTG
CTGCCCACGCCCAAGGGCTATCTCAAGCGGCTGCGCGAGATTTGCGACAAGTACGGCATCCTGCTCATCTTCGACGAGGT
CATCACCGGCTTCGGCCGCCTCGGCCATGCTTTCGCCGCCGAGCGCTACGGTGTGGTGCCGGACATGATCACCTTCGCCA
AGGGCATCACCGCGGGCGCCGTGCCCATGGGCGGCGTGCTGGTGCGCAAGGGCATCCATGATGCCTTCATGAAGGGACCG
GAGCACGTGGTGGAGCTGTTCCACGGCTACACCTATTCGGCCCATCCCCTGGCCTGCGCGGCGGGTCTTGCCACCCTCGA
CCTCTACGCCAGGGAGCACACCTTCACCCATGCCCGGGCGCTGGAGCCCTTCTTCGCCGACGCGATGATGAGCCTGAAGG
ACAAGCCCGGCGTGCTCGACATCCGCACGGTGGGCATCACCGGCGCCGTGGACCTCGCCCCCAAGGAAGGCGCTCCGGGC
CTGAAGGGCTACGAAGCGCTGGAGCGGGCCTTCCACGAGGAGGGCCTGATGATGCGCATCGCCGGCGACACGCTGGTGGT
GACGCCGCCGCTCATCATCTCGAAGGATCAGGTGGGCGAGCTGGTGGAGAAGCTGGGCCGGGTCATCGAAAAGGTGGCCT
GA

Upstream 100 bases:

>100_bases
GCCACGCGCACTGCTAGCTTCCGCACCGACGCGGCCGAAGAATGGCAGCCGGAAGGCCCGATCCCGCCTGAAGCTGCCGC
CGCGCGGGAGAGGTTTCATC

Downstream 100 bases:

>100_bases
CGCCAGCAATGCGCCGGCGGATCCGCCGGCGCGTTGTCATCAAAGGCCTGCCATGCGCCGGGCTGGACCCGGTAAGTAAA
GGCGGCAGGCCGGCATGGCC

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MALDDLVTEGAGVGADAIPNDLDAFWMPFTSNRSFKKRPRLVSRAKDMHYYTPEGRAILDGCAGLWCVNPGHNREPIVEA
IRQAATEVDFAPTFQYGHPQAFRLASRIADLAPGDLDHVFFCNSGSEAVDTALKIALAYHQTTGAGTRTRLIGRERGYHG
VGFGGISVGGIVSNRRTFGTMLTGVDHLRSTYDREHQAFTKGEPDYGAHFADELERIVALHDASTIASVIVEPMGGSTGV
LPTPKGYLKRLREICDKYGILLIFDEVITGFGRLGHAFAAERYGVVPDMITFAKGITAGAVPMGGVLVRKGIHDAFMKGP
EHVVELFHGYTYSAHPLACAAGLATLDLYAREHTFTHARALEPFFADAMMSLKDKPGVLDIRTVGITGAVDLAPKEGAPG
LKGYEALERAFHEEGLMMRIAGDTLVVTPPLIISKDQVGELVEKLGRVIEKVA

Sequences:

>Translated_453_residues
MALDDLVTEGAGVGADAIPNDLDAFWMPFTSNRSFKKRPRLVSRAKDMHYYTPEGRAILDGCAGLWCVNPGHNREPIVEA
IRQAATEVDFAPTFQYGHPQAFRLASRIADLAPGDLDHVFFCNSGSEAVDTALKIALAYHQTTGAGTRTRLIGRERGYHG
VGFGGISVGGIVSNRRTFGTMLTGVDHLRSTYDREHQAFTKGEPDYGAHFADELERIVALHDASTIASVIVEPMGGSTGV
LPTPKGYLKRLREICDKYGILLIFDEVITGFGRLGHAFAAERYGVVPDMITFAKGITAGAVPMGGVLVRKGIHDAFMKGP
EHVVELFHGYTYSAHPLACAAGLATLDLYAREHTFTHARALEPFFADAMMSLKDKPGVLDIRTVGITGAVDLAPKEGAPG
LKGYEALERAFHEEGLMMRIAGDTLVVTPPLIISKDQVGELVEKLGRVIEKVA
>Mature_452_residues
ALDDLVTEGAGVGADAIPNDLDAFWMPFTSNRSFKKRPRLVSRAKDMHYYTPEGRAILDGCAGLWCVNPGHNREPIVEAI
RQAATEVDFAPTFQYGHPQAFRLASRIADLAPGDLDHVFFCNSGSEAVDTALKIALAYHQTTGAGTRTRLIGRERGYHGV
GFGGISVGGIVSNRRTFGTMLTGVDHLRSTYDREHQAFTKGEPDYGAHFADELERIVALHDASTIASVIVEPMGGSTGVL
PTPKGYLKRLREICDKYGILLIFDEVITGFGRLGHAFAAERYGVVPDMITFAKGITAGAVPMGGVLVRKGIHDAFMKGPE
HVVELFHGYTYSAHPLACAAGLATLDLYAREHTFTHARALEPFFADAMMSLKDKPGVLDIRTVGITGAVDLAPKEGAPGL
KGYEALERAFHEEGLMMRIAGDTLVVTPPLIISKDQVGELVEKLGRVIEKVA

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=438, Percent_Identity=26.2557077625571, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI226442705, Length=435, Percent_Identity=25.7471264367816, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI13994255, Length=443, Percent_Identity=27.5395033860045, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI24119277, Length=432, Percent_Identity=26.6203703703704, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI4557809, Length=421, Percent_Identity=25.6532066508314, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI226442709, Length=373, Percent_Identity=26.8096514745308, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI284507298, Length=332, Percent_Identity=27.4096385542169, Blast_Score=103, Evalue=4e-22,
Organism=Escherichia coli, GI145693181, Length=402, Percent_Identity=29.6019900497512, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1786991, Length=441, Percent_Identity=29.7052154195011, Blast_Score=158, Evalue=9e-40,
Organism=Escherichia coli, GI1789016, Length=424, Percent_Identity=28.5377358490566, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788044, Length=433, Percent_Identity=27.0207852193995, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1789759, Length=409, Percent_Identity=28.361858190709, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1787560, Length=414, Percent_Identity=28.743961352657, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1786349, Length=358, Percent_Identity=27.0949720670391, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI32564660, Length=447, Percent_Identity=27.9642058165548, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71992977, Length=438, Percent_Identity=28.5388127853881, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=421, Percent_Identity=25.6532066508314, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI25144274, Length=249, Percent_Identity=30.5220883534137, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323470, Length=433, Percent_Identity=25.635103926097, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6324386, Length=477, Percent_Identity=24.1090146750524, Blast_Score=133, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6324432, Length=434, Percent_Identity=25.3456221198157, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI161085790, Length=434, Percent_Identity=26.7281105990783, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI28574759, Length=423, Percent_Identity=26.7139479905437, Blast_Score=121, Evalue=1e-27,
Organism=Drosophila melanogaster, GI21357415, Length=418, Percent_Identity=24.1626794258373, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21356575, Length=426, Percent_Identity=25.1173708920188, Blast_Score=95, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 48991; Mature: 48859

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDDLVTEGAGVGADAIPNDLDAFWMPFTSNRSFKKRPRLVSRAKDMHYYTPEGRAILD
CCHHHHHHCCCCCCCCCCCCCCHHEECCCCCCCCHHHHHHHHHHHHHCEEECCCCCCHHH
GCAGLWCVNPGHNREPIVEAIRQAATEVDFAPTFQYGHPQAFRLASRIADLAPGDLDHVF
CCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
FCNSGSEAVDTALKIALAYHQTTGAGTRTRLIGRERGYHGVGFGGISVGGIVSNRRTFGT
EECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHH
MLTGVDHLRSTYDREHQAFTKGEPDYGAHFADELERIVALHDASTIASVIVEPMGGSTGV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LPTPKGYLKRLREICDKYGILLIFDEVITGFGRLGHAFAAERYGVVPDMITFAKGITAGA
CCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
VPMGGVLVRKGIHDAFMKGPEHVVELFHGYTYSAHPLACAAGLATLDLYAREHTFTHARA
CCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LEPFFADAMMSLKDKPGVLDIRTVGITGAVDLAPKEGAPGLKGYEALERAFHEEGLMMRI
HHHHHHHHHHHHCCCCCEEEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEE
AGDTLVVTPPLIISKDQVGELVEKLGRVIEKVA
ECCEEEECCCCEECHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ALDDLVTEGAGVGADAIPNDLDAFWMPFTSNRSFKKRPRLVSRAKDMHYYTPEGRAILD
CHHHHHHCCCCCCCCCCCCCCHHEECCCCCCCCHHHHHHHHHHHHHCEEECCCCCCHHH
GCAGLWCVNPGHNREPIVEAIRQAATEVDFAPTFQYGHPQAFRLASRIADLAPGDLDHVF
CCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEE
FCNSGSEAVDTALKIALAYHQTTGAGTRTRLIGRERGYHGVGFGGISVGGIVSNRRTFGT
EECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCEEECCCCCCCHHHHH
MLTGVDHLRSTYDREHQAFTKGEPDYGAHFADELERIVALHDASTIASVIVEPMGGSTGV
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LPTPKGYLKRLREICDKYGILLIFDEVITGFGRLGHAFAAERYGVVPDMITFAKGITAGA
CCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
VPMGGVLVRKGIHDAFMKGPEHVVELFHGYTYSAHPLACAAGLATLDLYAREHTFTHARA
CCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LEPFFADAMMSLKDKPGVLDIRTVGITGAVDLAPKEGAPGLKGYEALERAFHEEGLMMRI
HHHHHHHHHHHHCCCCCEEEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEE
AGDTLVVTPPLIISKDQVGELVEKLGRVIEKVA
ECCEEEECCCCEECHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]