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The map label for this gene is hisE

Identifier: 154246230

GI number: 154246230

Start: 2554315

End: 2554641

Strand: Reverse

Name: hisE

Synonym: Xaut_2288

Alternate gene names: 154246230

Gene position: 2554641-2554315 (Counterclockwise)

Preceding gene: 154246231

Following gene: 154246229

Centisome position: 48.12

GC content: 68.5

Gene sequence:

>327_bases
ATGAGCGACAGCTTCACCCTCGCCGACCTCGAAGCCATCGTCGCGGCGCGCGCCTCGGCGGATGCGGGGGCGTCCTATAC
CCGCTCGCTGCTCGACAAGGGCATCGGGAAATGCGCCCAGAAGCTGGGCGAGGAGGCGGTGGAGACGGTAATTGCCGCCG
TCTCCGGCAGCGAGAAGGACCTCGTCGCGGAAACCAGCGATCTGCTCTACCATCTCCTCGTGCTGCTGAAGGCGCGCGGG
GTGCCGCTGGCCGAGATCCACGCGGAGCTTGCACGCCGAACCGGCCAATCCGGCCTCGCCGAAAAAGCCGCCCGGCAGCA
CGGCTGA

Upstream 100 bases:

>100_bases
CCAAGGAACGCCTTGCGGAAGCGGGGCTGCCTGTCCGCCTCGACGTCTAGGCCGCGCGCCTTAACGCGTCCTCCCCGCCC
TCCCTTTCCGGGCCACCTTG

Downstream 100 bases:

>100_bases
GAAGAGCACGAGGCACACCATGGATCGACGGCTCGACCCAGGCCTCTCTCCCTACCGCACCTTCTCGCGCGCCGAATGGG
CCGCGCTGAGGCGCGACACG

Product: phosphoribosyl-ATP pyrophosphatase

Products: NA

Alternate protein names: PRA-PH [H]

Number of amino acids: Translated: 108; Mature: 107

Protein sequence:

>108_residues
MSDSFTLADLEAIVAARASADAGASYTRSLLDKGIGKCAQKLGEEAVETVIAAVSGSEKDLVAETSDLLYHLLVLLKARG
VPLAEIHAELARRTGQSGLAEKAARQHG

Sequences:

>Translated_108_residues
MSDSFTLADLEAIVAARASADAGASYTRSLLDKGIGKCAQKLGEEAVETVIAAVSGSEKDLVAETSDLLYHLLVLLKARG
VPLAEIHAELARRTGQSGLAEKAARQHG
>Mature_107_residues
SDSFTLADLEAIVAARASADAGASYTRSLLDKGIGKCAQKLGEEAVETVIAAVSGSEKDLVAETSDLLYHLLVLLKARGV
PLAEIHAELARRTGQSGLAEKAARQHG

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0140

COG function: function code E; Phosphoribosyl-ATP pyrophosphohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-PH family [H]

Homologues:

Organism=Escherichia coli, GI2367128, Length=87, Percent_Identity=45.9770114942529, Blast_Score=73, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008179
- InterPro:   IPR021130 [H]

Pfam domain/function: PF01503 PRA-PH [H]

EC number: =3.6.1.31 [H]

Molecular weight: Translated: 11246; Mature: 11115

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSFTLADLEAIVAARASADAGASYTRSLLDKGIGKCAQKLGEEAVETVIAAVSGSEKD
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LVAETSDLLYHLLVLLKARGVPLAEIHAELARRTGQSGLAEKAARQHG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SDSFTLADLEAIVAARASADAGASYTRSLLDKGIGKCAQKLGEEAVETVIAAVSGSEKD
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LVAETSDLLYHLLVLLKARGVPLAEIHAELARRTGQSGLAEKAARQHG
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA