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The map label for this gene is coaA

Identifier: 154246229

GI number: 154246229

Start: 2553324

End: 2554295

Strand: Reverse

Name: coaA

Synonym: Xaut_2287

Alternate gene names: 154246229

Gene position: 2554295-2553324 (Counterclockwise)

Preceding gene: 154246230

Following gene: 154246227

Centisome position: 48.11

GC content: 65.64

Gene sequence:

>972_bases
ATGGATCGACGGCTCGACCCAGGCCTCTCTCCCTACCGCACCTTCTCGCGCGCCGAATGGGCCGCGCTGAGGCGCGACAC
GCCCATGACCCTGCGCCCGGACGAGATCACCCGGCTGGAGGGCCTCGGCGTCCATCTCTCCATGCAGGAGGTGGAGGAGA
TCTACCTCCCGCTGTCGCGGCTGCTCTCACTTTACGTAGCGGCAACGCAAAAGCTCTTCCGCGCCATGAGCTACTTCCTC
GACTCTCGCGACAGCGAGGCGAACGGGGACGGCAAGATGCCCTACATCATCGGGGTGGCCGGATCGGTGGCGGTGGGCAA
GTCCACCACCGCCCGCGTGCTCCAGGCGCTTCTGGCGCGCTGGCCCAACACACCCAAGGTGGATCTCGTCACCACCGACG
GCTTCCTCCTGCCCAACGCCATCCTCGAGCGCGAGGGGCTGATGGACAAGAAGGGCTTCCCCGAAAGCTACGACCTGCCG
CTGCTGCTGCGCTTCCTCACCGACATCAAGGCCGGCCGGCGGCCGGTGCGCGCGCCGCTCTATTCGCACTTCTTCTACGA
CGTGATGCCCGACCAGTATGTGGAGATCGACCGGCCCGACATCCTCATCGTGGAAGGCCTCAACGTGCTGCAGACCACGC
GTCCTCCGAAGGACGGCAAGGCCATTCCCTTCGTCTCGGACTTCTTCGATTTCTCGGTCTATATCGACGGCGACGAGGAC
GTGATCGAGCGCTGGTACGTGGAGCGCTTCATGCGGCTGCGGGCCACCGCCTTCAAGGACCCTTTGTCCTACTTCCACCG
CTACTCGCAGCTCACGGAAGAGCAGGCCCGCGCCACCGCCCTGTCCATCTGGCGCGGCATCAATCTGCCCAACCTCATGG
ACAATGTGCTGCCCACCCGCCAGCGCGCCGACCTCATCCTGCGCAAGACCGGCGAGCACGAGGTGGCGGAGGTCAGCCTG
CGCCGCCTGTAA

Upstream 100 bases:

>100_bases
CTGGCCGAGATCCACGCGGAGCTTGCACGCCGAACCGGCCAATCCGGCCTCGCCGAAAAAGCCGCCCGGCAGCACGGCTG
AGAAGAGCACGAGGCACACC

Downstream 100 bases:

>100_bases
TGCCGATCGTCCGTGAGATTGATTCACCGACGATCGCTCAAGCCCGCGCGGCGCTCAAGTGGACCGGCAGCTTCGGTCAA
CGACCGAGGCTGATGATATG

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MDRRLDPGLSPYRTFSRAEWAALRRDTPMTLRPDEITRLEGLGVHLSMQEVEEIYLPLSRLLSLYVAATQKLFRAMSYFL
DSRDSEANGDGKMPYIIGVAGSVAVGKSTTARVLQALLARWPNTPKVDLVTTDGFLLPNAILEREGLMDKKGFPESYDLP
LLLRFLTDIKAGRRPVRAPLYSHFFYDVMPDQYVEIDRPDILIVEGLNVLQTTRPPKDGKAIPFVSDFFDFSVYIDGDED
VIERWYVERFMRLRATAFKDPLSYFHRYSQLTEEQARATALSIWRGINLPNLMDNVLPTRQRADLILRKTGEHEVAEVSL
RRL

Sequences:

>Translated_323_residues
MDRRLDPGLSPYRTFSRAEWAALRRDTPMTLRPDEITRLEGLGVHLSMQEVEEIYLPLSRLLSLYVAATQKLFRAMSYFL
DSRDSEANGDGKMPYIIGVAGSVAVGKSTTARVLQALLARWPNTPKVDLVTTDGFLLPNAILEREGLMDKKGFPESYDLP
LLLRFLTDIKAGRRPVRAPLYSHFFYDVMPDQYVEIDRPDILIVEGLNVLQTTRPPKDGKAIPFVSDFFDFSVYIDGDED
VIERWYVERFMRLRATAFKDPLSYFHRYSQLTEEQARATALSIWRGINLPNLMDNVLPTRQRADLILRKTGEHEVAEVSL
RRL
>Mature_323_residues
MDRRLDPGLSPYRTFSRAEWAALRRDTPMTLRPDEITRLEGLGVHLSMQEVEEIYLPLSRLLSLYVAATQKLFRAMSYFL
DSRDSEANGDGKMPYIIGVAGSVAVGKSTTARVLQALLARWPNTPKVDLVTTDGFLLPNAILEREGLMDKKGFPESYDLP
LLLRFLTDIKAGRRPVRAPLYSHFFYDVMPDQYVEIDRPDILIVEGLNVLQTTRPPKDGKAIPFVSDFFDFSVYIDGDED
VIERWYVERFMRLRATAFKDPLSYFHRYSQLTEEQARATALSIWRGINLPNLMDNVLPTRQRADLILRKTGEHEVAEVSL
RRL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=315, Percent_Identity=54.2857142857143, Blast_Score=346, Evalue=1e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_XANP2 (A7IHN7)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001417187.1
- ProteinModelPortal:   A7IHN7
- SMR:   A7IHN7
- STRING:   A7IHN7
- GeneID:   5421276
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_2287
- eggNOG:   COG1072
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- ProtClustDB:   PRK05439
- BioCyc:   XAUT78245:XAUT_2287-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 37076; Mature: 37076

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRRLDPGLSPYRTFSRAEWAALRRDTPMTLRPDEITRLEGLGVHLSMQEVEEIYLPLSR
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHH
LLSLYVAATQKLFRAMSYFLDSRDSEANGDGKMPYIIGVAGSVAVGKSTTARVLQALLAR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
WPNTPKVDLVTTDGFLLPNAILEREGLMDKKGFPESYDLPLLLRFLTDIKAGRRPVRAPL
CCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHH
YSHFFYDVMPDQYVEIDRPDILIVEGLNVLQTTRPPKDGKAIPFVSDFFDFSVYIDGDED
HHHHHHHCCCCCEEECCCCCEEEECCCHHHHCCCCCCCCCCCCCHHHCCEEEEEECCCHH
VIERWYVERFMRLRATAFKDPLSYFHRYSQLTEEQARATALSIWRGINLPNLMDNVLPTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCH
QRADLILRKTGEHEVAEVSLRRL
HHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MDRRLDPGLSPYRTFSRAEWAALRRDTPMTLRPDEITRLEGLGVHLSMQEVEEIYLPLSR
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHH
LLSLYVAATQKLFRAMSYFLDSRDSEANGDGKMPYIIGVAGSVAVGKSTTARVLQALLAR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHH
WPNTPKVDLVTTDGFLLPNAILEREGLMDKKGFPESYDLPLLLRFLTDIKAGRRPVRAPL
CCCCCCEEEEECCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHH
YSHFFYDVMPDQYVEIDRPDILIVEGLNVLQTTRPPKDGKAIPFVSDFFDFSVYIDGDED
HHHHHHHCCCCCEEECCCCCEEEECCCHHHHCCCCCCCCCCCCCHHHCCEEEEEECCCHH
VIERWYVERFMRLRATAFKDPLSYFHRYSQLTEEQARATALSIWRGINLPNLMDNVLPTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCH
QRADLILRKTGEHEVAEVSLRRL
HHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA