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The map label for this gene is asd [H]

Identifier: 154246157

GI number: 154246157

Start: 2476354

End: 2477388

Strand: Reverse

Name: asd [H]

Synonym: Xaut_2214

Alternate gene names: 154246157

Gene position: 2477388-2476354 (Counterclockwise)

Preceding gene: 154246161

Following gene: 154246155

Centisome position: 46.66

GC content: 64.15

Gene sequence:

>1035_bases
ATGGGTTACAAGGTCGCCGTCGTCGGCGCCACGGGCAACGTGGGCCGGGAGATCCTCTCGATCCTCGCCGAGCGGGGCTT
TCCCGCGGACGAGGTTGTGGCGCTTGCTTCGCGCCGCTCGCAGGGCGTGGAAGTCTCCTTCGGTGACAAAACCCTCAAGG
TGAAGGCGCTCGAAACCTACGACTTCTCCGACACCGACATCTGCCTGATGTCGGCAGGCGGTGCCGTGTCGAAGGAATGG
TCGCCGAAGATCGGCGCGCAGGGCTGCGTCGTCATCGACAATTCGTCCCAGTGGCGCATGGATCCGGACGTGCCGCTGAT
CGTGCCCGAGGTGAATGCGGACGCCATCGTCGACTTCACCAAGAAGAACATCATCGCCAATCCCAACTGCTCCACGGCGC
AGTTGGTGGTGGCGCTGAAGCCGCTGCACGATGCCGCCACCATCAAGCGCGTGGTGGTTTCCACCTACCAGTCCGTCTCC
GGCGCCGGCAAGGACGCCATGGACGAGCTGTTCACCCAGACCCGGGCGATCTTCGTCTCCGATCCGGTGGAGCCGAAGAA
GTTCCCCAAGCGCATCGCCTTCAACCTCATTCCCCAGATCGACGTCTTCCTCGACGACGGCTCGACCAAGGAAGAGTGGA
AGATGGTGGCCGAGACCAAGAAGATCCTCGATCCGAAGATCAAGCTCACGGCCACCTGCGTGCGTGTGCCGGTGTTCATC
TCCCACTCGGAATCGGTGAACGTCGAGTTCGAGAAGGAGCTGTCCGCCGAGGACGCGCGCAAGATCCTGCGCGAGGCCCC
GGGTATCCTCGTCATCGACACCCGTGAGCCGGGCGGCTACGCCACCCCGCACGAGGCCGCCGGCGAGGACGCCACCTTCA
TCTCGCGCCTGCGCGATGACCCGACCGTGGACAACGCCATCAACTTCTGGTGCGTGTCCGATAACCTGCGCAAGGGCGCA
GCCCTCAACGCGGTGCAGATCGCCGAGGTGCTGGTGAACCGCAAGCTCATCACTGCCCGCAGCAAGGCAGCCTGA

Upstream 100 bases:

>100_bases
TCGCTGTGCGCGCTCGCGGAATCTTCAGTTTGCAAGCGCGGGCCGTTCGGCCTAAAACCCCCGTTCCGGCCAGCAGGGCC
GGCAGATCCCGAGGAATATC

Downstream 100 bases:

>100_bases
GGGCGCCTGCGCTTTCCCTGAAGACTGTGAACGGCCCTCTTCGGAGGGCCGTTTTCGTTTGGGGCCTCAGGCAGGTCCCG
CCGGATCGACGGCAGAGGCC

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MGYKVAVVGATGNVGREILSILAERGFPADEVVALASRRSQGVEVSFGDKTLKVKALETYDFSDTDICLMSAGGAVSKEW
SPKIGAQGCVVIDNSSQWRMDPDVPLIVPEVNADAIVDFTKKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQSVS
GAGKDAMDELFTQTRAIFVSDPVEPKKFPKRIAFNLIPQIDVFLDDGSTKEEWKMVAETKKILDPKIKLTATCVRVPVFI
SHSESVNVEFEKELSAEDARKILREAPGILVIDTREPGGYATPHEAAGEDATFISRLRDDPTVDNAINFWCVSDNLRKGA
ALNAVQIAEVLVNRKLITARSKAA

Sequences:

>Translated_344_residues
MGYKVAVVGATGNVGREILSILAERGFPADEVVALASRRSQGVEVSFGDKTLKVKALETYDFSDTDICLMSAGGAVSKEW
SPKIGAQGCVVIDNSSQWRMDPDVPLIVPEVNADAIVDFTKKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQSVS
GAGKDAMDELFTQTRAIFVSDPVEPKKFPKRIAFNLIPQIDVFLDDGSTKEEWKMVAETKKILDPKIKLTATCVRVPVFI
SHSESVNVEFEKELSAEDARKILREAPGILVIDTREPGGYATPHEAAGEDATFISRLRDDPTVDNAINFWCVSDNLRKGA
ALNAVQIAEVLVNRKLITARSKAA
>Mature_343_residues
GYKVAVVGATGNVGREILSILAERGFPADEVVALASRRSQGVEVSFGDKTLKVKALETYDFSDTDICLMSAGGAVSKEWS
PKIGAQGCVVIDNSSQWRMDPDVPLIVPEVNADAIVDFTKKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQSVSG
AGKDAMDELFTQTRAIFVSDPVEPKKFPKRIAFNLIPQIDVFLDDGSTKEEWKMVAETKKILDPKIKLTATCVRVPVFIS
HSESVNVEFEKELSAEDARKILREAPGILVIDTREPGGYATPHEAAGEDATFISRLRDDPTVDNAINFWCVSDNLRKGAA
LNAVQIAEVLVNRKLITARSKAA

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=342, Percent_Identity=37.1345029239766, Blast_Score=224, Evalue=8e-60,
Organism=Escherichia coli, GI1789841, Length=361, Percent_Identity=29.3628808864266, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6320362, Length=402, Percent_Identity=29.3532338308458, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37344; Mature: 37213

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYKVAVVGATGNVGREILSILAERGFPADEVVALASRRSQGVEVSFGDKTLKVKALETY
CCEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCEEEEEEEEEC
DFSDTDICLMSAGGAVSKEWSPKIGAQGCVVIDNSSQWRMDPDVPLIVPEVNADAIVDFT
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCEEEECCCCCCEEEEH
KKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQSVSGAGKDAMDELFTQTRAIFVS
HCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEE
DPVEPKKFPKRIAFNLIPQIDVFLDDGSTKEEWKMVAETKKILDPKIKLTATCVRVPVFI
CCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEE
SHSESVNVEFEKELSAEDARKILREAPGILVIDTREPGGYATPHEAAGEDATFISRLRDD
ECCCCCCEEEHHHCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCC
PTVDNAINFWCVSDNLRKGAALNAVQIAEVLVNRKLITARSKAA
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCHHEECCCCCC
>Mature Secondary Structure 
GYKVAVVGATGNVGREILSILAERGFPADEVVALASRRSQGVEVSFGDKTLKVKALETY
CEEEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCEEEEEEEEEC
DFSDTDICLMSAGGAVSKEWSPKIGAQGCVVIDNSSQWRMDPDVPLIVPEVNADAIVDFT
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCEEECCCCCEEEECCCCCCEEEEH
KKNIIANPNCSTAQLVVALKPLHDAATIKRVVVSTYQSVSGAGKDAMDELFTQTRAIFVS
HCCEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEEEEE
DPVEPKKFPKRIAFNLIPQIDVFLDDGSTKEEWKMVAETKKILDPKIKLTATCVRVPVFI
CCCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEE
SHSESVNVEFEKELSAEDARKILREAPGILVIDTREPGGYATPHEAAGEDATFISRLRDD
ECCCCCCEEEHHHCCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCC
PTVDNAINFWCVSDNLRKGAALNAVQIAEVLVNRKLITARSKAA
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCHHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]