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The map label for this gene is pqqL [C]

Identifier: 154246147

GI number: 154246147

Start: 2463928

End: 2465337

Strand: Reverse

Name: pqqL [C]

Synonym: Xaut_2204

Alternate gene names: 154246147

Gene position: 2465337-2463928 (Counterclockwise)

Preceding gene: 154246148

Following gene: 154246146

Centisome position: 46.44

GC content: 68.09

Gene sequence:

>1410_bases
ATGACGGAAGATCGCCACGTGTTCATGAGCCGCCTCACCATGATTGCTATTCTCGCCGCCACCGCGGCCACAGCCGCCCC
CCGCATTGCTGACGCGGCGGGGCCGGACGTTACCCAGTTCCAGCTCGACAACGGCCTTCAGGTCATGGTCATCCCGGACC
ACCGCACGCCGGTGGTCACCCACATGGTGTGGTACAAGGTGGGATCGGCCGACGAGCAGGCCGGCAAGTCCGGCATTGCC
CATTTCCTCGAGCACCTGATGTTCAAGGGCACCGACGCCCACCCGCAGGGCCAGTTCTCGGCCGAGGTGGCGCGTCTCGG
CGGCCAGGAGAACGCCTTCACCTCGCAGGACTACACCGCCTATTTCCAGCGCGTCGCCAAGGAGCACCTGGAAAAGGTGA
TGGGCTTCGAAGCCGACCGCATGACCGGCCTCAAGCTCTCCGACGAGGTGGTGCTGCCCGAGCGCGACGTGGTGCTGGAA
GAGCGCCGCATGCGTACCGACAACGACCCCGGCGCGCGCCTCTCCGAGGTGCTGCAGGCCACGACCTACGTCAACCACCC
CTATCAGCACCCCATCATCGGCTGGGAGCACGAGATCAAGGGGCTGAACCGCGAGGATGCCCTCGCCTTCTACCGCCGTT
ATTACGCGCCCAACAACGCGCTGCTCGTGGTGGCCGGCGACGTGGACCCGGAGACGGTCCGCACCCTCGCCGAGAAGACC
TACGGCAAGGTGGCCCGCGCCGACACCCCGCCCCGCAACCGCCCGCAGGAACCCGAGCCCCAGGCCCACCGCCGGGTGGC
GCTGTCCGACCCGCGCGTGGCCCAGCCGAGCCTGCAGCGCTCCTATCTGGTGCCCTCCTCCCGCACCGCCCAGCCGGGCG
AGGCCGAGGCGCTGGAAGTGCTCGGCCAGATCCTCGGCGGCGGCCAGACCAGCCGCCTCTACCGTACCTTGGTGGCCGAG
AAGGGCATCGCCGCCGGTTCCGGCTCCTGGTATCAAAGCACCGCATATGATGCCACCCGCTTCGTCACCTATGCTTCGCC
CCGCCCGGGCGTGAGCCTGGAGGACCTTGAGGCGGCCGTGGACGCGGTGATCACCGAGCTGCAGGAAAAGGGCGTGGACG
ACCTGGAGCTGGCCCGCGCCAAGACCCGGCTTACCGCCGACACCATCTATTCGCAGGACAACCAGGCCACCCTCGCCCGC
ATCTACGGCGCCTCCTGGGCCACCGGCATGTCGGCCGACGATGTGCGGGCCTGGCCGGACCGCATCAAGGCGGTGACCGC
CGAGCAGGTGAAGGACGTGGCGCGCCGGTACCTTGTCACCAATCGCGCCGTCACCGGCTACCTGAAGCAGTCGGAGCCGA
AAAAGGACGCCGCTCCGAAAGCTGAAATCAAGAAGGACGACCGCTCGTGA

Upstream 100 bases:

>100_bases
AAGTTAATCCACCGGGCGGGGCGATGTTGACGGGCGCAACCTTTGCTTCCGCGCCCGGCTTCCTATCTTTCCTTGACGTG
CCCGTCGTTCGGCGCGTCGA

Downstream 100 bases:

>100_bases
GGGCTGGCCCCGCCCCCCTTTTCGACCAGACCGGCAGCGCCCTGCGCGCCGGTCGTCTCCTCTTTGCGATGGTAACCATG
GCCCTTTCCCTTCTTTCCGC

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 468

Protein sequence:

>469_residues
MTEDRHVFMSRLTMIAILAATAATAAPRIADAAGPDVTQFQLDNGLQVMVIPDHRTPVVTHMVWYKVGSADEQAGKSGIA
HFLEHLMFKGTDAHPQGQFSAEVARLGGQENAFTSQDYTAYFQRVAKEHLEKVMGFEADRMTGLKLSDEVVLPERDVVLE
ERRMRTDNDPGARLSEVLQATTYVNHPYQHPIIGWEHEIKGLNREDALAFYRRYYAPNNALLVVAGDVDPETVRTLAEKT
YGKVARADTPPRNRPQEPEPQAHRRVALSDPRVAQPSLQRSYLVPSSRTAQPGEAEALEVLGQILGGGQTSRLYRTLVAE
KGIAAGSGSWYQSTAYDATRFVTYASPRPGVSLEDLEAAVDAVITELQEKGVDDLELARAKTRLTADTIYSQDNQATLAR
IYGASWATGMSADDVRAWPDRIKAVTAEQVKDVARRYLVTNRAVTGYLKQSEPKKDAAPKAEIKKDDRS

Sequences:

>Translated_469_residues
MTEDRHVFMSRLTMIAILAATAATAAPRIADAAGPDVTQFQLDNGLQVMVIPDHRTPVVTHMVWYKVGSADEQAGKSGIA
HFLEHLMFKGTDAHPQGQFSAEVARLGGQENAFTSQDYTAYFQRVAKEHLEKVMGFEADRMTGLKLSDEVVLPERDVVLE
ERRMRTDNDPGARLSEVLQATTYVNHPYQHPIIGWEHEIKGLNREDALAFYRRYYAPNNALLVVAGDVDPETVRTLAEKT
YGKVARADTPPRNRPQEPEPQAHRRVALSDPRVAQPSLQRSYLVPSSRTAQPGEAEALEVLGQILGGGQTSRLYRTLVAE
KGIAAGSGSWYQSTAYDATRFVTYASPRPGVSLEDLEAAVDAVITELQEKGVDDLELARAKTRLTADTIYSQDNQATLAR
IYGASWATGMSADDVRAWPDRIKAVTAEQVKDVARRYLVTNRAVTGYLKQSEPKKDAAPKAEIKKDDRS
>Mature_468_residues
TEDRHVFMSRLTMIAILAATAATAAPRIADAAGPDVTQFQLDNGLQVMVIPDHRTPVVTHMVWYKVGSADEQAGKSGIAH
FLEHLMFKGTDAHPQGQFSAEVARLGGQENAFTSQDYTAYFQRVAKEHLEKVMGFEADRMTGLKLSDEVVLPERDVVLEE
RRMRTDNDPGARLSEVLQATTYVNHPYQHPIIGWEHEIKGLNREDALAFYRRYYAPNNALLVVAGDVDPETVRTLAEKTY
GKVARADTPPRNRPQEPEPQAHRRVALSDPRVAQPSLQRSYLVPSSRTAQPGEAEALEVLGQILGGGQTSRLYRTLVAEK
GIAAGSGSWYQSTAYDATRFVTYASPRPGVSLEDLEAAVDAVITELQEKGVDDLELARAKTRLTADTIYSQDNQATLARI
YGASWATGMSADDVRAWPDRIKAVTAEQVKDVARRYLVTNRAVTGYLKQSEPKKDAAPKAEIKKDDRS

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=438, Percent_Identity=25.3424657534247, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI94538354, Length=208, Percent_Identity=28.3653846153846, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI155969707, Length=285, Percent_Identity=25.6140350877193, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI1787770, Length=244, Percent_Identity=29.5081967213115, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI2367164, Length=232, Percent_Identity=26.7241379310345, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71999683, Length=395, Percent_Identity=23.5443037974684, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17553678, Length=239, Percent_Identity=29.2887029288703, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6323192, Length=233, Percent_Identity=30.4721030042918, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6323421, Length=297, Percent_Identity=24.5791245791246, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357875, Length=458, Percent_Identity=25.764192139738, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24646943, Length=458, Percent_Identity=25.764192139738, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 51848; Mature: 51717

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEDRHVFMSRLTMIAILAATAATAAPRIADAAGPDVTQFQLDNGLQVMVIPDHRTPVVT
CCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEECCCCEEEEECCCCCCHHH
HMVWYKVGSADEQAGKSGIAHFLEHLMFKGTDAHPQGQFSAEVARLGGQENAFTSQDYTA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHH
YFQRVAKEHLEKVMGFEADRMTGLKLSDEVVLPERDVVLEERRMRTDNDPGARLSEVLQA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCHHHHHHHHCCCCCCCCHHHHHHHHH
TTYVNHPYQHPIIGWEHEIKGLNREDALAFYRRYYAPNNALLVVAGDVDPETVRTLAEKT
HHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
YGKVARADTPPRNRPQEPEPQAHRRVALSDPRVAQPSLQRSYLVPSSRTAQPGEAEALEV
HHHHHCCCCCCCCCCCCCCCHHHCEEECCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHH
LGQILGGGQTSRLYRTLVAEKGIAAGSGSWYQSTAYDATRFVTYASPRPGVSLEDLEAAV
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHEEEEECCCCCCCCHHHHHHHH
DAVITELQEKGVDDLELARAKTRLTADTIYSQDNQATLARIYGASWATGMSADDVRAWPD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHH
RIKAVTAEQVKDVARRYLVTNRAVTGYLKQSEPKKDAAPKAEIKKDDRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TEDRHVFMSRLTMIAILAATAATAAPRIADAAGPDVTQFQLDNGLQVMVIPDHRTPVVT
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCEEEEECCCCEEEEECCCCCCHHH
HMVWYKVGSADEQAGKSGIAHFLEHLMFKGTDAHPQGQFSAEVARLGGQENAFTSQDYTA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHHH
YFQRVAKEHLEKVMGFEADRMTGLKLSDEVVLPERDVVLEERRMRTDNDPGARLSEVLQA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECCCCHHHHHHHHCCCCCCCCHHHHHHHHH
TTYVNHPYQHPIIGWEHEIKGLNREDALAFYRRYYAPNNALLVVAGDVDPETVRTLAEKT
HHHHCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHH
YGKVARADTPPRNRPQEPEPQAHRRVALSDPRVAQPSLQRSYLVPSSRTAQPGEAEALEV
HHHHHCCCCCCCCCCCCCCCHHHCEEECCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHH
LGQILGGGQTSRLYRTLVAEKGIAAGSGSWYQSTAYDATRFVTYASPRPGVSLEDLEAAV
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCHHEEEEECCCCCCCCHHHHHHHH
DAVITELQEKGVDDLELARAKTRLTADTIYSQDNQATLARIYGASWATGMSADDVRAWPD
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCHHHHHHH
RIKAVTAEQVKDVARRYLVTNRAVTGYLKQSEPKKDAAPKAEIKKDDRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]