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The map label for this gene is cph2 [H]

Identifier: 154246138

GI number: 154246138

Start: 2454006

End: 2455496

Strand: Direct

Name: cph2 [H]

Synonym: Xaut_2195

Alternate gene names: 154246138

Gene position: 2454006-2455496 (Clockwise)

Preceding gene: 154246137

Following gene: 154246139

Centisome position: 46.22

GC content: 69.35

Gene sequence:

>1491_bases
ATGCACACCAGGACACCGCCCGTCGCGTCGTTGCCCGATGTGACACCTGCAAGCCTGCGCCATACGGTGGCCTTGTCGCT
GGTGCTCGCCGCCGCCTATGTGGTGCTGGGGCGGCTGACGTTCGCTGTTTCGGTGGAGTACGGCAACGTCACCAGCGTGG
TGTTCGCGCCGGAGGGTGTGGCGCTGGCCTTCTGCATCCTGTTCGGGCCGCGGGTGGCGCTGGGCATCTTTCTCGGCCAG
ACCATCCTGTCCCTGTGGTCGGGGCCCTCGCTGCTCGGCGGGGCGGTCATCGGCCTCACCAATGCCGCAGAGGGCGCGCT
CGGCGGCTGGCTGTTCCGGCGCATGGCGATCTCGCCGCGCTTCGGCCGCCCGCGCGACGTGGCTCTGTTCGTGGCGCTGG
TGTTCCTGATCCTGCAGCCCGTCAGCGCCAGCGGCGGCGTGCTGGTGCTGTACCTGCTGGGAGCCATCCCCACTGACCTC
ATCCCGGCGGATTGGGCGCCGTGGTGGATCCAGGGCCTGCAGAAACCCCTGCCGTCGCTGGATCTGGTGCCCTCGGCCTG
GGTGCACTGGTGGATCGGCAATTCGGTGGGGCAACTGCTGGTGGCGCCGCTCATCCTCGCCTGGAGCACGCCGCCCACTC
CCGGAGCGCCCAAGGGTTGGCTCGACATCATGCTGAGCGCTGGCGGGGTCGTGCTGGTGGCTGCGCTGACCCTGAGCGGG
ATTCCGACCCATCCCCTGCTCCTGCTTGCCATGACCTATTTCCTGCTGGTGTGGATCGGGCTCCGGCGCGGGCTCAGAGG
CATCACCCTCGCCAACGTGCTCATCGGCGCCGCGGTGACCTGGGCGGGGGCATCGGGGGCGGGGTTCATGTCCCACCTGT
CGGTGGCCGACCGCCTGTCCAACGTGGGCTTCTTCGTGGCGGCTGCGTGCACCTTTTCCCTGATGCTGTTCGCCATGTTC
GAGGAGCGGCGCCTCCTCATCGACCGGCTGACCCGGCTCGCCTCGTGGGATTCGCTGGTCGAGCTTCACAACCGCCGCCA
TTTCATCGAGAGGGCGGATCGCGAGGTGGCCGCCGCGCAGCGCTACGGCCGCGACCTGGTGCTGCTCATGCTCGATGCCG
ACAATTTCAAGGAGCTGAACGACCAATACGGCCATGCCGCCGGGGATGCCGCCCTGAAGATGATCGCGGAGGCCTGCGCG
GCGGTGGCGCGCCAGACTGACGTGACGGGCCGGATCGGCGGCGAGGAATTCGCGATGCTGCTGCCTCACGCCACCCTTGA
CGGTGGTCAGGCCCTGGCGGAACGGCTGCGCCGGCAGATCGAGGCCACCCCGGTCCAGATCGCGACCGGCCGTCCCTTCC
ATGTCACCGTCAGCATCGGCATTGCCCGGCTGGGCCGGCGGGACGGCCTCGATGCGCTGATGCGTGCCGCTGACCGGGCG
CTCTATGCCGCCAAGCGGGCCGGTCGCAACCGGGCAGCGCTGGCGGATTGA

Upstream 100 bases:

>100_bases
ATTCCTGTCCCCAAGGTAATGCGGTATCAACGAGCGTAGAGCATCGGCCACCGCCGCGTCGTGGACGGAACCGAGCCACG
AACCGTCGGCCGAGAGCTCG

Downstream 100 bases:

>100_bases
GGGGCTGGCGGCATCCCATACCTTGACGCCGCAGCGCTCTGCCCCTATACGAGCCGCTTCCCGATAGAGCGGGTGAGTGC
GGCAGGGTCGTCTGGCCCCG

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 496; Mature: 496

Protein sequence:

>496_residues
MHTRTPPVASLPDVTPASLRHTVALSLVLAAAYVVLGRLTFAVSVEYGNVTSVVFAPEGVALAFCILFGPRVALGIFLGQ
TILSLWSGPSLLGGAVIGLTNAAEGALGGWLFRRMAISPRFGRPRDVALFVALVFLILQPVSASGGVLVLYLLGAIPTDL
IPADWAPWWIQGLQKPLPSLDLVPSAWVHWWIGNSVGQLLVAPLILAWSTPPTPGAPKGWLDIMLSAGGVVLVAALTLSG
IPTHPLLLLAMTYFLLVWIGLRRGLRGITLANVLIGAAVTWAGASGAGFMSHLSVADRLSNVGFFVAAACTFSLMLFAMF
EERRLLIDRLTRLASWDSLVELHNRRHFIERADREVAAAQRYGRDLVLLMLDADNFKELNDQYGHAAGDAALKMIAEACA
AVARQTDVTGRIGGEEFAMLLPHATLDGGQALAERLRRQIEATPVQIATGRPFHVTVSIGIARLGRRDGLDALMRAADRA
LYAAKRAGRNRAALAD

Sequences:

>Translated_496_residues
MHTRTPPVASLPDVTPASLRHTVALSLVLAAAYVVLGRLTFAVSVEYGNVTSVVFAPEGVALAFCILFGPRVALGIFLGQ
TILSLWSGPSLLGGAVIGLTNAAEGALGGWLFRRMAISPRFGRPRDVALFVALVFLILQPVSASGGVLVLYLLGAIPTDL
IPADWAPWWIQGLQKPLPSLDLVPSAWVHWWIGNSVGQLLVAPLILAWSTPPTPGAPKGWLDIMLSAGGVVLVAALTLSG
IPTHPLLLLAMTYFLLVWIGLRRGLRGITLANVLIGAAVTWAGASGAGFMSHLSVADRLSNVGFFVAAACTFSLMLFAMF
EERRLLIDRLTRLASWDSLVELHNRRHFIERADREVAAAQRYGRDLVLLMLDADNFKELNDQYGHAAGDAALKMIAEACA
AVARQTDVTGRIGGEEFAMLLPHATLDGGQALAERLRRQIEATPVQIATGRPFHVTVSIGIARLGRRDGLDALMRAADRA
LYAAKRAGRNRAALAD
>Mature_496_residues
MHTRTPPVASLPDVTPASLRHTVALSLVLAAAYVVLGRLTFAVSVEYGNVTSVVFAPEGVALAFCILFGPRVALGIFLGQ
TILSLWSGPSLLGGAVIGLTNAAEGALGGWLFRRMAISPRFGRPRDVALFVALVFLILQPVSASGGVLVLYLLGAIPTDL
IPADWAPWWIQGLQKPLPSLDLVPSAWVHWWIGNSVGQLLVAPLILAWSTPPTPGAPKGWLDIMLSAGGVVLVAALTLSG
IPTHPLLLLAMTYFLLVWIGLRRGLRGITLANVLIGAAVTWAGASGAGFMSHLSVADRLSNVGFFVAAACTFSLMLFAMF
EERRLLIDRLTRLASWDSLVELHNRRHFIERADREVAAAQRYGRDLVLLMLDADNFKELNDQYGHAAGDAALKMIAEACA
AVARQTDVTGRIGGEEFAMLLPHATLDGGQALAERLRRQIEATPVQIATGRPFHVTVSIGIARLGRRDGLDALMRAADRA
LYAAKRAGRNRAALAD

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=39.2405063291139, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87081881, Length=174, Percent_Identity=38.5057471264368, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=34.8837209302326, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082007, Length=163, Percent_Identity=36.1963190184049, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786584, Length=168, Percent_Identity=32.1428571428571, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1787802, Length=173, Percent_Identity=30.635838150289, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1788085, Length=184, Percent_Identity=28.804347826087, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788381, Length=185, Percent_Identity=31.8918918918919, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787816, Length=167, Percent_Identity=32.3353293413174, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87081974, Length=180, Percent_Identity=26.1111111111111, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787541, Length=171, Percent_Identity=34.5029239766082, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081977, Length=179, Percent_Identity=26.8156424581006, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788956, Length=120, Percent_Identity=36.6666666666667, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 53052; Mature: 53052

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTRTPPVASLPDVTPASLRHTVALSLVLAAAYVVLGRLTFAVSVEYGNVTSVVFAPEGV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEECCCCH
ALAFCILFGPRVALGIFLGQTILSLWSGPSLLGGAVIGLTNAAEGALGGWLFRRMAISPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHEECCCCCHHHHHHHHHHHHCCCC
FGRPRDVALFVALVFLILQPVSASGGVLVLYLLGAIPTDLIPADWAPWWIQGLQKPLPSL
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCC
DLVPSAWVHWWIGNSVGQLLVAPLILAWSTPPTPGAPKGWLDIMLSAGGVVLVAALTLSG
CCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCC
IPTHPLLLLAMTYFLLVWIGLRRGLRGITLANVLIGAAVTWAGASGAGFMSHLSVADRLS
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
NVGFFVAAACTFSLMLFAMFEERRLLIDRLTRLASWDSLVELHNRRHFIERADREVAAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYGRDLVLLMLDADNFKELNDQYGHAAGDAALKMIAEACAAVARQTDVTGRIGGEEFAML
HCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LPHATLDGGQALAERLRRQIEATPVQIATGRPFHVTVSIGIARLGRRDGLDALMRAADRA
CCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEHHHHHCCCCCHHHHHHHHHHH
LYAAKRAGRNRAALAD
HHHHHHCCCCCCCCCC
>Mature Secondary Structure
MHTRTPPVASLPDVTPASLRHTVALSLVLAAAYVVLGRLTFAVSVEYGNVTSVVFAPEGV
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEECCCCH
ALAFCILFGPRVALGIFLGQTILSLWSGPSLLGGAVIGLTNAAEGALGGWLFRRMAISPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHEECCCCCHHHHHHHHHHHHCCCC
FGRPRDVALFVALVFLILQPVSASGGVLVLYLLGAIPTDLIPADWAPWWIQGLQKPLPSL
CCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCCC
DLVPSAWVHWWIGNSVGQLLVAPLILAWSTPPTPGAPKGWLDIMLSAGGVVLVAALTLSG
CCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHCC
IPTHPLLLLAMTYFLLVWIGLRRGLRGITLANVLIGAAVTWAGASGAGFMSHLSVADRLS
CCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
NVGFFVAAACTFSLMLFAMFEERRLLIDRLTRLASWDSLVELHNRRHFIERADREVAAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RYGRDLVLLMLDADNFKELNDQYGHAAGDAALKMIAEACAAVARQTDVTGRIGGEEFAML
HCCCEEEEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LPHATLDGGQALAERLRRQIEATPVQIATGRPFHVTVSIGIARLGRRDGLDALMRAADRA
CCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEHHHHHCCCCCHHHHHHHHHHH
LYAAKRAGRNRAALAD
HHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]