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The map label for this gene is rppH [H]

Identifier: 154246088

GI number: 154246088

Start: 2407019

End: 2407537

Strand: Direct

Name: rppH [H]

Synonym: Xaut_2145

Alternate gene names: 154246088

Gene position: 2407019-2407537 (Clockwise)

Preceding gene: 154246087

Following gene: 154246089

Centisome position: 45.34

GC content: 65.7

Gene sequence:

>519_bases
ATGTCCAATCGTCACGACAAGAAACAGGACGACCTGCCGTACCGCCCCTGCGTGGGCCTGTGTGTGTTCAATGCGGCCGG
CAAGGTCTTCCTCGGCCGGCGCATCGGCGGGCCGGAGCACGTGGACGCCACCCATTCCTGGCAGCTGCCCCAGGGCGGCA
TCGACAAGGGCGAGGAGCCGTTCGCCGCCGCCTTGCGCGAGCTCTACGAGGAGACTTCCATGCGCTCGGTGACGAAGCTC
GCCGAGGTGGGAGAGTGGTTGTCCTACGATCTGCCGGGTCGAATCGCCGGCGAGGCCTGGAAGGGCAAGTATCGCGGCCA
GACACAGAAATGGTTCGCCCTGCGCTTCACGGGCCTCGATGCCGAGATCAACATCACCCGCCCCGGCGGCGGGCATCACA
AGCCCGAATTCATGGACTGGCGCTGGGAGAGCCTCGACAAGGTGGCGGACCTCGTCGTGCCGTTCAAGCGCAGGGTCTAT
GACGAGGTGGTGAAGGCCTTCCGCCCGTTCTCCGGATAG

Upstream 100 bases:

>100_bases
GACCGCCGCGTCATCGCGGGGTGCCTGAAGGCATGGGGCCTTGCGCGGCGACGCCGCGCGGGCCAATCAGGAGTTAGCAA
CTCTCCTTCGGATCACGACC

Downstream 100 bases:

>100_bases
CGAAGCGTCGCTCTTCGCATCTGAATGATGGTGGCGACGGAAGTATCGGGCGGCGAGACGATGCCTGCCGAGATGAAATC
GAAAGAAATAGATTAGGCGA

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase [H]

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MSNRHDKKQDDLPYRPCVGLCVFNAAGKVFLGRRIGGPEHVDATHSWQLPQGGIDKGEEPFAAALRELYEETSMRSVTKL
AEVGEWLSYDLPGRIAGEAWKGKYRGQTQKWFALRFTGLDAEINITRPGGGHHKPEFMDWRWESLDKVADLVVPFKRRVY
DEVVKAFRPFSG

Sequences:

>Translated_172_residues
MSNRHDKKQDDLPYRPCVGLCVFNAAGKVFLGRRIGGPEHVDATHSWQLPQGGIDKGEEPFAAALRELYEETSMRSVTKL
AEVGEWLSYDLPGRIAGEAWKGKYRGQTQKWFALRFTGLDAEINITRPGGGHHKPEFMDWRWESLDKVADLVVPFKRRVY
DEVVKAFRPFSG
>Mature_171_residues
SNRHDKKQDDLPYRPCVGLCVFNAAGKVFLGRRIGGPEHVDATHSWQLPQGGIDKGEEPFAAALRELYEETSMRSVTKLA
EVGEWLSYDLPGRIAGEAWKGKYRGQTQKWFALRFTGLDAEINITRPGGGHHKPEFMDWRWESLDKVADLVVPFKRRVYD
EVVKAFRPFSG

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1789194, Length=160, Percent_Identity=43.75, Blast_Score=110, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 19578; Mature: 19447

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNRHDKKQDDLPYRPCVGLCVFNAAGKVFLGRRIGGPEHVDATHSWQLPQGGIDKGEEP
CCCCCCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCH
FAAALRELYEETSMRSVTKLAEVGEWLSYDLPGRIAGEAWKGKYRGQTQKWFALRFTGLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCEEEEEEEECCC
AEINITRPGGGHHKPEFMDWRWESLDKVADLVVPFKRRVYDEVVKAFRPFSG
CEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SNRHDKKQDDLPYRPCVGLCVFNAAGKVFLGRRIGGPEHVDATHSWQLPQGGIDKGEEP
CCCCCCCCCCCCCCCHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCH
FAAALRELYEETSMRSVTKLAEVGEWLSYDLPGRIAGEAWKGKYRGQTQKWFALRFTGLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCEEEEEEEECCC
AEINITRPGGGHHKPEFMDWRWESLDKVADLVVPFKRRVYDEVVKAFRPFSG
CEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA