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The map label for this gene is dsbD [H]

Identifier: 154245023

GI number: 154245023

Start: 1232339

End: 1234162

Strand: Reverse

Name: dsbD [H]

Synonym: Xaut_1074

Alternate gene names: 154245023

Gene position: 1234162-1232339 (Counterclockwise)

Preceding gene: 154245026

Following gene: 154245022

Centisome position: 23.25

GC content: 73.63

Gene sequence:

>1824_bases
ATGGTCGCGAACCCGCCTCGCTCTCCCCTGTCGCCCCTCCGCCGCGCACTCGCCACGCTGGTGGTGGTCGTGCTGTGGGC
CACCGGCGCCGCCCCTGTGCTGGCGCAGGGCGGCATCCTGAAGGCGGACGAGGCCTTCACCGTCTCCGCGACACGGGCGA
CCGACGGCACCCTCTCCCTGAGCTGGCGCATCGCGCCGGGCACCTATCTCTATCGCGAGAGCCTGAAGGCCGGGAAGGAC
GGCACCGCTGTCCCTCTCACACTGCCGCCGGGCGAAGAGAAGGACGATCCGAACTTCGGGCCGGTGGACATCTATCACCG
GTCCGTCACGGCCAGCGCGCCTGCCCTGCCGGAGACCGGGGCGCTGGAACTCTCGTTTCAGGGCTGCGCCGAGCAGGGGG
TCTGCTACCCCGCTGTCACGCGGCAAATAGACCTCGCCACGCTGACGATCACCGCGGCCCGTCCGCGCGTCGAAGCGTCG
CCGGTGGATCAATGGGGGACCGCCGCGCCCCCGCCCAAGCCTGCCGCAGCGCCCGGGACCCCCGCGCAGCCCGCCGCCCT
AGATGCGCTGTTCCGCAGGGACCTGTTGCCCCTGCTCGGGGCCTTCTTCGGCCTCGGCCTGCTGCTCGCCTTCACCCCTT
GCGTCTTCCCCATGCTGCCGATCCTTTCCGGCATCCTCGCCGGCGGCGGCGCGAAGCCGACACCGGCCCGCGGCCTCGTC
TTGTCCGGGTCTTATGGACTGGCCATGGCCGCCGCCTATGGCGTGCTCGGCATGGGCGCTGCCTGGACCGGCGCCAACCT
GCAGGCTGCGCTGCAGACGCCGTGGGCCATCGGCCTGATGGCTGCGGTGTTCGCCGTGCTGGCCGGCGCGATGGTCGGCC
TCTTCGATCTCGCAATCCCGTCTGCGCTGGCCGCACGGCTGCCGTCGGGCGGGAGCGGCTCCATCGCGGGAGCGGCGGGG
CTGGGCTTCGCTTCGGCGCTGGTGGTGGGGCCGTGCGTGACGCCGCCGCTCGCCGCCGCCATGCTTTATGCGGCGCAGAC
GGGCGATGCCGCGCGCGGCGCCTCCGCCCTGTTCATGCTCGGCCTCGGGATGGCGGCGCCGCTGGTGGCGGTGGGTGCGT
TCGGCGCGCAGATCCTGCCCCGGTCGGGACGCTGGCTTCTCGCCGTCAAGCAAGGCTGCGGCGTGCTCTTCCTCGCCATC
GCCGCATGGCTCGCGGCGCGCGTCTTGCCAGATTCTGCCGGCCTTGCCCTCTACGGCCTTCTCGCCATCGGCCTCGGCGT
GTTCGCCGGCGGCTTCGATGCGCTGGCCTCCGACGCCGATGCCGGCCGCCGCATCGGCAAGACGGCGGGCATCGCCGCCG
TGGCGGCCGGGCTCCTGCTCCTGGTCGGAGCCGCCGGCGGGGCCAGCGATCCGCTGCGGCCTCTCGCCTTTCTCGCAGCA
CCGGCCCGCCCCGCCGCTGCGGCGGAGCGGGAAGTGCGGGTGTCCTCTCCCCCCGCTCTGGCGCGCGCGCTCGCCGCGGC
CGGTCAGCATGGCCGCCCGACGCTCGTCTCCTTCACCGCCGACTGGTGCACGGTCTGCAAGTCCAACGAGACGACCATGG
CGGAGCCCGCTGTGGCCGCGCGCCTGTCCGGGCTCGAACGCATCGCCGTGGACGTGACCCGGTATGGCGACGGCGCGCGC
GCCCTCATGGGCCGCTACGAGGTCATCGGCCCGCCGACCCTGTTCCTCCTCGATCCGGACGGCCGCGAATTGCCGGGATC
GCGCCGCGTGGGCGCGCTGACCCTCGCCGACATCGACCGCCTCGCCACCCAGGCGGGGCTGTGA

Upstream 100 bases:

>100_bases
CGTCCTCGACGACCAGTATGCGCATCAGACCGCTCTCCTCGCCCCTTCCCTTCTATCCCGACCTTAAGGCCCGCTTAAGG
TGGACATCCGAGGGAGCGTC

Downstream 100 bases:

>100_bases
CCCCATGACCGAAGGATACCCCATGCGACGCAGGGACTTCATCCGCATCGCCGCGCTCACCGCGCTGATGCCGGCCGCGG
TGGCGGGCGCAGGCCGGGCA

Product: cytochrome c biogenesis protein transmembrane subunit

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MVANPPRSPLSPLRRALATLVVVVLWATGAAPVLAQGGILKADEAFTVSATRATDGTLSLSWRIAPGTYLYRESLKAGKD
GTAVPLTLPPGEEKDDPNFGPVDIYHRSVTASAPALPETGALELSFQGCAEQGVCYPAVTRQIDLATLTITAARPRVEAS
PVDQWGTAAPPPKPAAAPGTPAQPAALDALFRRDLLPLLGAFFGLGLLLAFTPCVFPMLPILSGILAGGGAKPTPARGLV
LSGSYGLAMAAAYGVLGMGAAWTGANLQAALQTPWAIGLMAAVFAVLAGAMVGLFDLAIPSALAARLPSGGSGSIAGAAG
LGFASALVVGPCVTPPLAAAMLYAAQTGDAARGASALFMLGLGMAAPLVAVGAFGAQILPRSGRWLLAVKQGCGVLFLAI
AAWLAARVLPDSAGLALYGLLAIGLGVFAGGFDALASDADAGRRIGKTAGIAAVAAGLLLLVGAAGGASDPLRPLAFLAA
PARPAAAAEREVRVSSPPALARALAAAGQHGRPTLVSFTADWCTVCKSNETTMAEPAVAARLSGLERIAVDVTRYGDGAR
ALMGRYEVIGPPTLFLLDPDGRELPGSRRVGALTLADIDRLATQAGL

Sequences:

>Translated_607_residues
MVANPPRSPLSPLRRALATLVVVVLWATGAAPVLAQGGILKADEAFTVSATRATDGTLSLSWRIAPGTYLYRESLKAGKD
GTAVPLTLPPGEEKDDPNFGPVDIYHRSVTASAPALPETGALELSFQGCAEQGVCYPAVTRQIDLATLTITAARPRVEAS
PVDQWGTAAPPPKPAAAPGTPAQPAALDALFRRDLLPLLGAFFGLGLLLAFTPCVFPMLPILSGILAGGGAKPTPARGLV
LSGSYGLAMAAAYGVLGMGAAWTGANLQAALQTPWAIGLMAAVFAVLAGAMVGLFDLAIPSALAARLPSGGSGSIAGAAG
LGFASALVVGPCVTPPLAAAMLYAAQTGDAARGASALFMLGLGMAAPLVAVGAFGAQILPRSGRWLLAVKQGCGVLFLAI
AAWLAARVLPDSAGLALYGLLAIGLGVFAGGFDALASDADAGRRIGKTAGIAAVAAGLLLLVGAAGGASDPLRPLAFLAA
PARPAAAAEREVRVSSPPALARALAAAGQHGRPTLVSFTADWCTVCKSNETTMAEPAVAARLSGLERIAVDVTRYGDGAR
ALMGRYEVIGPPTLFLLDPDGRELPGSRRVGALTLADIDRLATQAGL
>Mature_607_residues
MVANPPRSPLSPLRRALATLVVVVLWATGAAPVLAQGGILKADEAFTVSATRATDGTLSLSWRIAPGTYLYRESLKAGKD
GTAVPLTLPPGEEKDDPNFGPVDIYHRSVTASAPALPETGALELSFQGCAEQGVCYPAVTRQIDLATLTITAARPRVEAS
PVDQWGTAAPPPKPAAAPGTPAQPAALDALFRRDLLPLLGAFFGLGLLLAFTPCVFPMLPILSGILAGGGAKPTPARGLV
LSGSYGLAMAAAYGVLGMGAAWTGANLQAALQTPWAIGLMAAVFAVLAGAMVGLFDLAIPSALAARLPSGGSGSIAGAAG
LGFASALVVGPCVTPPLAAAMLYAAQTGDAARGASALFMLGLGMAAPLVAVGAFGAQILPRSGRWLLAVKQGCGVLFLAI
AAWLAARVLPDSAGLALYGLLAIGLGVFAGGFDALASDADAGRRIGKTAGIAAVAAGLLLLVGAAGGASDPLRPLAFLAA
PARPAAAAEREVRVSSPPALARALAAAGQHGRPTLVSFTADWCTVCKSNETTMAEPAVAARLSGLERIAVDVTRYGDGAR
ALMGRYEVIGPPTLFLLDPDGRELPGSRRVGALTLADIDRLATQAGL

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=565, Percent_Identity=32.0353982300885, Blast_Score=256, Evalue=3e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 61020; Mature: 61020

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVANPPRSPLSPLRRALATLVVVVLWATGAAPVLAQGGILKADEAFTVSATRATDGTLSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEECCCCEEEEEECCCCCEEEE
SWRIAPGTYLYRESLKAGKDGTAVPLTLPPGEEKDDPNFGPVDIYHRSVTASAPALPETG
EEEECCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCEEEECEECCCCCCCCCCC
ALELSFQGCAEQGVCYPAVTRQIDLATLTITAARPRVEASPVDQWGTAAPPPKPAAAPGT
CEEEEECCCCCCCCCCHHHHCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAQPAALDALFRRDLLPLLGAFFGLGLLLAFTPCVFPMLPILSGILAGGGAKPTPARGLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
LSGSYGLAMAAAYGVLGMGAAWTGANLQAALQTPWAIGLMAAVFAVLAGAMVGLFDLAIP
EECCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SALAARLPSGGSGSIAGAAGLGFASALVVGPCVTPPLAAAMLYAAQTGDAARGASALFML
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
GLGMAAPLVAVGAFGAQILPRSGRWLLAVKQGCGVLFLAIAAWLAARVLPDSAGLALYGL
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
LAIGLGVFAGGFDALASDADAGRRIGKTAGIAAVAAGLLLLVGAAGGASDPLRPLAFLAA
HHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHC
PARPAAAAEREVRVSSPPALARALAAAGQHGRPTLVSFTADWCTVCKSNETTMAEPAVAA
CCCCCHHCCCCEECCCCHHHHHHHHHCCCCCCCEEEEECHHHHHHHCCCCCCCCCHHHHH
RLSGLERIAVDVTRYGDGARALMGRYEVIGPPTLFLLDPDGRELPGSRRVGALTLADIDR
HHHCHHHHEEEHHHCCCHHHHHHCCCEEECCCEEEEECCCCCCCCCCCCCCEEEHHHHHH
LATQAGL
HHHHCCC
>Mature Secondary Structure
MVANPPRSPLSPLRRALATLVVVVLWATGAAPVLAQGGILKADEAFTVSATRATDGTLSL
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEECCCCEEEEEECCCCCEEEE
SWRIAPGTYLYRESLKAGKDGTAVPLTLPPGEEKDDPNFGPVDIYHRSVTASAPALPETG
EEEECCCHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCEEEECEECCCCCCCCCCC
ALELSFQGCAEQGVCYPAVTRQIDLATLTITAARPRVEASPVDQWGTAAPPPKPAAAPGT
CEEEEECCCCCCCCCCHHHHCEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
PAQPAALDALFRRDLLPLLGAFFGLGLLLAFTPCVFPMLPILSGILAGGGAKPTPARGLV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEE
LSGSYGLAMAAAYGVLGMGAAWTGANLQAALQTPWAIGLMAAVFAVLAGAMVGLFDLAIP
EECCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SALAARLPSGGSGSIAGAAGLGFASALVVGPCVTPPLAAAMLYAAQTGDAARGASALFML
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
GLGMAAPLVAVGAFGAQILPRSGRWLLAVKQGCGVLFLAIAAWLAARVLPDSAGLALYGL
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCHHHHHH
LAIGLGVFAGGFDALASDADAGRRIGKTAGIAAVAAGLLLLVGAAGGASDPLRPLAFLAA
HHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHC
PARPAAAAEREVRVSSPPALARALAAAGQHGRPTLVSFTADWCTVCKSNETTMAEPAVAA
CCCCCHHCCCCEECCCCHHHHHHHHHCCCCCCCEEEEECHHHHHHHCCCCCCCCCHHHHH
RLSGLERIAVDVTRYGDGARALMGRYEVIGPPTLFLLDPDGRELPGSRRVGALTLADIDR
HHHCHHHHEEEHHHCCCHHHHHHCCCEEECCCEEEEECCCCCCCCCCCCCCEEEHHHHHH
LATQAGL
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA