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The map label for this gene is astD [H]

Identifier: 154244854

GI number: 154244854

Start: 1006201

End: 1007862

Strand: Direct

Name: astD [H]

Synonym: Xaut_0904

Alternate gene names: 154244854

Gene position: 1006201-1007862 (Clockwise)

Preceding gene: 154244850

Following gene: 154244855

Centisome position: 18.95

GC content: 70.16

Gene sequence:

>1662_bases
ATGGATGATCTGTTCCAGGCGCATGCCGCGCTGCTGGAGAAGGCCGTTGCGGCATCGCGCGAGCGCGGCTTCTGGGCGGC
GTTTGCGGAAAATCCCAAGGCCTATCCGGAAGGCGCCGCGAGCGCCGGCAAGGCGGCTTTCGCTGCCCTGAAGGGTCAGC
CGTTCGATCTTGGCGAAGAGGGGGGGCAGGCAGGGGAGGGCGCCCGCGTCGGCGCCGAGGTCTCGCCCTTCGGTCCGGCG
CTGGGCATCACCTATGCCGCGCGCAGCGTCGATGCGCTGGTGGCCCATGCGGAACGCGCCGGCGAGGGCTGGGCGCAGGC
ATCCGTGGAGCAGCGGGTGGGGGTGGCGCTGGAAATCCTGGCGCGCCTCAATGCCGAAAGCTTCCTCATCGCCGAGGCGG
TGGAGCACACCACCGGGCAGGCCGGCCCCATGGCCTTCCAGGCCGGCGGCCCCCATGCGCAGGATCGCGGGCTGGAGGCG
GTAGCCTATGCCTATGCCGAGATGGCGCGGGTGCCGGGCGCGGTGCGCTGGGAGAAGCCCATGGGGCGCTCGTCCATCCG
CCTCGACAAGGATTTCCATGTGGTGCCGCGCGGCATCGGCCTCGTCATCGGCTGTGCCACCTTTCCCACCTGGAACAGCT
ATCCGGCCCTGTTCGCCGATCTCGTCACCGGCAATGCGGTGATCGTGAAGCCCCACCCCGCCGCCATCCTGCCCTTGGCC
CTTACCGTGAAAATCGGCCGCGAAGTGCTCGCCGCGCAGGGCTTCGACCCGGACGTGCTCCAGCTTGCCCCCGACACGGT
GGAGGCGCCGCTCGCCAAGGATCTGGCGACCCACCCCGCCATCGGCCTCGTGGATTTCACCGGCTCGTCGGCCTTCGGCA
GCTGGCTGCGCGAGACCCTGCGGGACAAGCTGGTGTTCACGGAGGAGGCGGGGGTGAACACCATCGTCATCGCCTCCACC
GGCGCGTTCGCGGCCATGTGCGCCAACATCGCCTTCTCGCTCTCGCTCTACAGCGGGCAGATGTGCACCGCGCCGCAGAC
CATCTTCGTTCCGGCGGCGGGTATCGCCACGGAGGAGGGCCACAAGAGCTTCGATGAGGTGGCCGCAGGCATCGGCGCCG
CCATCGACGCGCTGTTGTCGGACCCTGCCCGCGCGGCGGCGGTGCTCGGCGCCATCCAGAATCCGGCAACGCTCACGCGA
ATCGAGGAGGCGCGCGGTCTCGGTCGCATCGTGCGCGACAGCGCGGCGCTTCAGGTGGAAGGCGCCCGCACAGCCACGCC
GCTGCTTCTCGCCGTGGATGCGACCGATGAGGCGGCCTATTTGGAAGAGCGCTTCGGCCCCATCGCCTTCGTGGTGGCGG
TCAAGGATGCGCAGGACGCCATCGCCCGCGCCACCCGCGCCGCACGGGAAAAGGGTGCCATCACCGCCGCCCTCTACAGC
ACCGACGAGGCCGAGATCGCCGCCGCCATCCCCGCCTATGCCAAGGCGGGCGTGGCGCTTTCGGTGAACCTCACCGGCGG
CATCTATGTGAACCAGAGCGCGGCGTTCAGCGACTACCACGTCTCCGGCGCCAACCCCGCCGGCAACGCCTGCATGACGG
ATTCAGCCTTCGTGGCGAGCCGCTTCCGCGTGGTGTGCGTGCGCCGCCCGGCCGCCGCCTGA

Upstream 100 bases:

>100_bases
CCGGGAGGGGACGCCGGCCGGTCGCGGCGATCGGGCGGCAAGGTCCCTCGCAAACCAGAACAGCGCCTGGCCAGCACGGC
CAGGCCTCAGGGAGAAGGCC

Downstream 100 bases:

>100_bases
AACCTGACATCAGGAGAAGAACAATGGCGCACGCCTTTATCTGCGATTTCGCGCGCACCCCCATCGGCCGCTATGCCGGC
GCCCTGAAGGATGTGCGCGC

Product: phenylacetic acid degradation protein paaN

Products: NA

Alternate protein names: Succinylglutamic semialdehyde dehydrogenase; SGSD [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MDDLFQAHAALLEKAVAASRERGFWAAFAENPKAYPEGAASAGKAAFAALKGQPFDLGEEGGQAGEGARVGAEVSPFGPA
LGITYAARSVDALVAHAERAGEGWAQASVEQRVGVALEILARLNAESFLIAEAVEHTTGQAGPMAFQAGGPHAQDRGLEA
VAYAYAEMARVPGAVRWEKPMGRSSIRLDKDFHVVPRGIGLVIGCATFPTWNSYPALFADLVTGNAVIVKPHPAAILPLA
LTVKIGREVLAAQGFDPDVLQLAPDTVEAPLAKDLATHPAIGLVDFTGSSAFGSWLRETLRDKLVFTEEAGVNTIVIAST
GAFAAMCANIAFSLSLYSGQMCTAPQTIFVPAAGIATEEGHKSFDEVAAGIGAAIDALLSDPARAAAVLGAIQNPATLTR
IEEARGLGRIVRDSAALQVEGARTATPLLLAVDATDEAAYLEERFGPIAFVVAVKDAQDAIARATRAAREKGAITAALYS
TDEAEIAAAIPAYAKAGVALSVNLTGGIYVNQSAAFSDYHVSGANPAGNACMTDSAFVASRFRVVCVRRPAAA

Sequences:

>Translated_553_residues
MDDLFQAHAALLEKAVAASRERGFWAAFAENPKAYPEGAASAGKAAFAALKGQPFDLGEEGGQAGEGARVGAEVSPFGPA
LGITYAARSVDALVAHAERAGEGWAQASVEQRVGVALEILARLNAESFLIAEAVEHTTGQAGPMAFQAGGPHAQDRGLEA
VAYAYAEMARVPGAVRWEKPMGRSSIRLDKDFHVVPRGIGLVIGCATFPTWNSYPALFADLVTGNAVIVKPHPAAILPLA
LTVKIGREVLAAQGFDPDVLQLAPDTVEAPLAKDLATHPAIGLVDFTGSSAFGSWLRETLRDKLVFTEEAGVNTIVIAST
GAFAAMCANIAFSLSLYSGQMCTAPQTIFVPAAGIATEEGHKSFDEVAAGIGAAIDALLSDPARAAAVLGAIQNPATLTR
IEEARGLGRIVRDSAALQVEGARTATPLLLAVDATDEAAYLEERFGPIAFVVAVKDAQDAIARATRAAREKGAITAALYS
TDEAEIAAAIPAYAKAGVALSVNLTGGIYVNQSAAFSDYHVSGANPAGNACMTDSAFVASRFRVVCVRRPAAA
>Mature_553_residues
MDDLFQAHAALLEKAVAASRERGFWAAFAENPKAYPEGAASAGKAAFAALKGQPFDLGEEGGQAGEGARVGAEVSPFGPA
LGITYAARSVDALVAHAERAGEGWAQASVEQRVGVALEILARLNAESFLIAEAVEHTTGQAGPMAFQAGGPHAQDRGLEA
VAYAYAEMARVPGAVRWEKPMGRSSIRLDKDFHVVPRGIGLVIGCATFPTWNSYPALFADLVTGNAVIVKPHPAAILPLA
LTVKIGREVLAAQGFDPDVLQLAPDTVEAPLAKDLATHPAIGLVDFTGSSAFGSWLRETLRDKLVFTEEAGVNTIVIAST
GAFAAMCANIAFSLSLYSGQMCTAPQTIFVPAAGIATEEGHKSFDEVAAGIGAAIDALLSDPARAAAVLGAIQNPATLTR
IEEARGLGRIVRDSAALQVEGARTATPLLLAVDATDEAAYLEERFGPIAFVVAVKDAQDAIARATRAAREKGAITAALYS
TDEAEIAAAIPAYAKAGVALSVNLTGGIYVNQSAAFSDYHVSGANPAGNACMTDSAFVASRFRVVCVRRPAAA

Specific function: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate [H]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. AstD subfamily [H]

Homologues:

Organism=Caenorhabditis elegans, GI115534176, Length=301, Percent_Identity=23.5880398671096, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 280 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR017649 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.71 [H]

Molecular weight: Translated: 57164; Mature: 57164

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDLFQAHAALLEKAVAASRERGFWAAFAENPKAYPEGAASAGKAAFAALKGQPFDLGEE
CCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCC
GGQAGEGARVGAEVSPFGPALGITYAARSVDALVAHAERAGEGWAQASVEQRVGVALEIL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ARLNAESFLIAEAVEHTTGQAGPMAFQAGGPHAQDRGLEAVAYAYAEMARVPGAVRWEKP
HHCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHCCHHHHHHHHHHHHHCCCCEEECCC
MGRSSIRLDKDFHVVPRGIGLVIGCATFPTWNSYPALFADLVTGNAVIVKPHPAAILPLA
CCCCCEEECCCCEECCCCCEEEEEECCCCCCCCCHHHHHHHHCCCEEEECCCCCCHHHHH
LTVKIGREVLAAQGFDPDVLQLAPDTVEAPLAKDLATHPAIGLVDFTGSSAFGSWLRETL
HHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
RDKLVFTEEAGVNTIVIASTGAFAAMCANIAFSLSLYSGQMCTAPQTIFVPAAGIATEEG
HHHEEEEECCCCCEEEEECCCHHHHHHHHHHHEEEEECCCCCCCCCEEEEECCCCCCCCC
HKSFDEVAAGIGAAIDALLSDPARAAAVLGAIQNPATLTRIEEARGLGRIVRDSAALQVE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEC
GARTATPLLLAVDATDEAAYLEERFGPIAFVVAVKDAQDAIARATRAAREKGAITAALYS
CCCCCCCEEEEEECCCHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEC
TDEAEIAAAIPAYAKAGVALSVNLTGGIYVNQSAAFSDYHVSGANPAGNACMTDSAFVAS
CCCHHHHHHHHHHHHCCEEEEEEECCCEEEECCCCCCCEEECCCCCCCCCCCCCHHHHHH
RFRVVCVRRPAAA
CEEEEEEECCCCC
>Mature Secondary Structure
MDDLFQAHAALLEKAVAASRERGFWAAFAENPKAYPEGAASAGKAAFAALKGQPFDLGEE
CCHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCC
GGQAGEGARVGAEVSPFGPALGITYAARSVDALVAHAERAGEGWAQASVEQRVGVALEIL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
ARLNAESFLIAEAVEHTTGQAGPMAFQAGGPHAQDRGLEAVAYAYAEMARVPGAVRWEKP
HHCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCHHCCHHHHHHHHHHHHHCCCCEEECCC
MGRSSIRLDKDFHVVPRGIGLVIGCATFPTWNSYPALFADLVTGNAVIVKPHPAAILPLA
CCCCCEEECCCCEECCCCCEEEEEECCCCCCCCCHHHHHHHHCCCEEEECCCCCCHHHHH
LTVKIGREVLAAQGFDPDVLQLAPDTVEAPLAKDLATHPAIGLVDFTGSSAFGSWLRETL
HHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHH
RDKLVFTEEAGVNTIVIASTGAFAAMCANIAFSLSLYSGQMCTAPQTIFVPAAGIATEEG
HHHEEEEECCCCCEEEEECCCHHHHHHHHHHHEEEEECCCCCCCCCEEEEECCCCCCCCC
HKSFDEVAAGIGAAIDALLSDPARAAAVLGAIQNPATLTRIEEARGLGRIVRDSAALQVE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEC
GARTATPLLLAVDATDEAAYLEERFGPIAFVVAVKDAQDAIARATRAAREKGAITAALYS
CCCCCCCEEEEEECCCHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHHHCCCEEEEEEC
TDEAEIAAAIPAYAKAGVALSVNLTGGIYVNQSAAFSDYHVSGANPAGNACMTDSAFVAS
CCCHHHHHHHHHHHHCCEEEEEEECCCEEEECCCCCCCEEECCCCCCCCCCCCCHHHHHH
RFRVVCVRRPAAA
CEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA