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The map label for this gene is insF1 [H]

Identifier: 154244634

GI number: 154244634

Start: 772896

End: 773771

Strand: Reverse

Name: insF1 [H]

Synonym: Xaut_0683

Alternate gene names: 154244634

Gene position: 773771-772896 (Counterclockwise)

Preceding gene: 154244635

Following gene: 154244628

Centisome position: 14.57

GC content: 64.38

Gene sequence:

>876_bases
GTGAAGTACGCGTTCATCGCCGAGCATCGCCTTCTGTTTTCGATCCGTGCCATGTGTCGGTGCCTGCGTGTCCAGCCTAG
CGGCTTCTACGCTTGGCTGAAGGACCCGCTGAGCAAGCGCGCGCAGGAAGACCAGCGACAGACCGAGCTGATCCGCGCGG
CATGGAGCGAGAGCGGCAAGGTCTATGGCTATCGCAAGCTTCACGACGATCTGGCGGACATGGGCGAGAGCTGCTGCCCC
AACCGGGTTGCGCGGCTGACGCGGCTTGCCGGCATCCGGGCGCAGATCGGCTACAGGCGGCGCCCCGGCCAATATGGAGG
CAAGCCATCCCTGGCGGTCGACAACACGCTCGATCGCCGGTTTGACGCGGAGGCGCCTGACAAGGCCTGGGTGACCGACA
TCACCTACATCCGCACCCACGAAGGCTTCGCCTATCTGGCGGTCGTGATCGACCTCTTCTCCCGCCGCGTCGTCGGCTGG
TCCATGCAGGCCCGGCAGACGACCAACGTCGTGCTTCAGGCGCTGCTGGCCGCCGTCTGGCGACGCAAGCCGAAGGGCCG
TGTGCTGGTGCATTCGGATCAGGGGAGCCAGTTCACCAGCATGGAGTGGGCTTCGTTCCTGAAACACCACGATCTGCAGC
CCTCGATGAGCCGTCGCGGGAACTGCCATGACAACGCTGTGGCCGAGAGCTTCTTCAACCTGCTCAAGCGCGAGCGCATC
CGCCGCAAGGTCTACCGCACGCGAGACGAGGCACGCCGGGACGTGTTCGATTACATCGAGATGTTCTACAACCCCACCCG
CAAACACGCACGCAACGGGATGCTGTCGCCCATCGAGTTCGAACGGCAGCACAAAGCGACCCCCGAAGGCGTCTAG

Upstream 100 bases:

>100_bases
AGGCCGCTGAGGTTCGCAGGCTGAAGCGCGAGTTGCAGCGCGTGACGGAGGAGCGCGACATCCTAAAAAAAGCGGCCGCG
TACTTCGCCAAGGATGCAAA

Downstream 100 bases:

>100_bases
AAAACTCGGGGCGGTTCAATGCCGCGCGCGCGGGCGAGGTTGTCGGCGACACCGTAATCCCCTTTGCCGTTCCCGTTCTG
CTCGAACCAGGTGATGGCGA

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKYAFIAEHRLLFSIRAMCRCLRVQPSGFYAWLKDPLSKRAQEDQRQTELIRAAWSESGKVYGYRKLHDDLADMGESCCP
NRVARLTRLAGIRAQIGYRRRPGQYGGKPSLAVDNTLDRRFDAEAPDKAWVTDITYIRTHEGFAYLAVVIDLFSRRVVGW
SMQARQTTNVVLQALLAAVWRRKPKGRVLVHSDQGSQFTSMEWASFLKHHDLQPSMSRRGNCHDNAVAESFFNLLKRERI
RRKVYRTRDEARRDVFDYIEMFYNPTRKHARNGMLSPIEFERQHKATPEGV

Sequences:

>Translated_291_residues
MKYAFIAEHRLLFSIRAMCRCLRVQPSGFYAWLKDPLSKRAQEDQRQTELIRAAWSESGKVYGYRKLHDDLADMGESCCP
NRVARLTRLAGIRAQIGYRRRPGQYGGKPSLAVDNTLDRRFDAEAPDKAWVTDITYIRTHEGFAYLAVVIDLFSRRVVGW
SMQARQTTNVVLQALLAAVWRRKPKGRVLVHSDQGSQFTSMEWASFLKHHDLQPSMSRRGNCHDNAVAESFFNLLKRERI
RRKVYRTRDEARRDVFDYIEMFYNPTRKHARNGMLSPIEFERQHKATPEGV
>Mature_291_residues
MKYAFIAEHRLLFSIRAMCRCLRVQPSGFYAWLKDPLSKRAQEDQRQTELIRAAWSESGKVYGYRKLHDDLADMGESCCP
NRVARLTRLAGIRAQIGYRRRPGQYGGKPSLAVDNTLDRRFDAEAPDKAWVTDITYIRTHEGFAYLAVVIDLFSRRVVGW
SMQARQTTNVVLQALLAAVWRRKPKGRVLVHSDQGSQFTSMEWASFLKHHDLQPSMSRRGNCHDNAVAESFFNLLKRERI
RRKVYRTRDEARRDVFDYIEMFYNPTRKHARNGMLSPIEFERQHKATPEGV

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=241, Percent_Identity=34.4398340248963, Blast_Score=139, Evalue=3e-33,
Organism=Escherichia coli, GI1788405, Length=288, Percent_Identity=43.0555555555556, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1787263, Length=288, Percent_Identity=43.0555555555556, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1786753, Length=288, Percent_Identity=43.0555555555556, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1786570, Length=288, Percent_Identity=43.0555555555556, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1786490, Length=288, Percent_Identity=43.0555555555556, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI1789981, Length=280, Percent_Identity=32.8571428571429, Blast_Score=134, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33914; Mature: 33914

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYAFIAEHRLLFSIRAMCRCLRVQPSGFYAWLKDPLSKRAQEDQRQTELIRAAWSESGK
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VYGYRKLHDDLADMGESCCPNRVARLTRLAGIRAQIGYRRRPGQYGGKPSLAVDNTLDRR
EEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCHHHHC
FDAEAPDKAWVTDITYIRTHEGFAYLAVVIDLFSRRVVGWSMQARQTTNVVLQALLAAVW
CCCCCCCCHHHHHHHEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RRKPKGRVLVHSDQGSQFTSMEWASFLKHHDLQPSMSRRGNCHDNAVAESFFNLLKRERI
CCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHH
RRKVYRTRDEARRDVFDYIEMFYNPTRKHARNGMLSPIEFERQHKATPEGV
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MKYAFIAEHRLLFSIRAMCRCLRVQPSGFYAWLKDPLSKRAQEDQRQTELIRAAWSESGK
CCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VYGYRKLHDDLADMGESCCPNRVARLTRLAGIRAQIGYRRRPGQYGGKPSLAVDNTLDRR
EEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEECCHHHHC
FDAEAPDKAWVTDITYIRTHEGFAYLAVVIDLFSRRVVGWSMQARQTTNVVLQALLAAVW
CCCCCCCCHHHHHHHEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
RRKPKGRVLVHSDQGSQFTSMEWASFLKHHDLQPSMSRRGNCHDNAVAESFFNLLKRERI
CCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHH
RRKVYRTRDEARRDVFDYIEMFYNPTRKHARNGMLSPIEFERQHKATPEGV
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]