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The map label for this gene is cutL [H]

Identifier: 154244600

GI number: 154244600

Start: 728328

End: 730685

Strand: Reverse

Name: cutL [H]

Synonym: Xaut_0648

Alternate gene names: 154244600

Gene position: 730685-728328 (Counterclockwise)

Preceding gene: 154244601

Following gene: 154244599

Centisome position: 13.76

GC content: 69.21

Gene sequence:

>2358_bases
ATGAGCGAGACCCAGATGCACGAAGGCGTCGGCGCCCGTCTTCCCCGCAAGGAAGACGACCGGCTGATGCGCGGGCGCGG
CCAGTTCATCGCCGATATCCGCATGACCGGCATGCAGGACGTGGCCTTCGTCCGCAGCCCTTTGGCCCATGCCCGCATCT
GCGCCATCCACGTGCCGGACGACCTGAAGGGCCGCGTCTTCACCGCCGCCGATCTCGACGGGGTGAAGCCCATCCGCGCC
GTCTCCGGACTACCGGGCTTCAAGGTGTCCGAACAGCCGGTGCTGGCCCTCGGCAAGGTGCGGCAGGTGGGCGAATTGAT
CGCCATATGCGTCGCCGACACCCGCGCCGAGGCCGAGGACATGGCCGCCCGCGTGGAGCTGGATCTCGAGGAGCTGCCCG
CCCTCCACGACATGCTGGAGGCGCGCAAGCCCGGCGCGCGCCTCGTGCACGAGCATTGGGGCGACAACGTCTTCCTCGAA
AGCCTCGTGAACATCAATATCGAGGCCGCCTTCGACGCGCCGGTGAAGGTCTCGCGCACCATTTCCACCGCGCGCCAATG
CATGGCTCCCATCGAGGGGCGCGGCGCCATCATCCATTTCGACCACCGCAGCGACCAGCTGGTGGTGCACACCGCCAGCC
AGATGCCGCACATCGTGCGCTCAGGCCTCTCCGAATGCCTCTCGATGGAAGAAGGCCAGATCCGCATCATCTCCCCGGAT
GTGGGCGGAGGCTTCGGCTACAAGGCCATCCTGCTGGCGGAGGAGGTCTGCCTCGGCTGGCTGGCGCAGAAGCTGCGCCG
CCCGGTGCGCTGGCTGGAAGACCGGCGCGAACACCTCACCGCCAACGCCAATTGCCGCGAGCACCATTACGAGATCACGC
TCTATGCCGAGCGCGACGGGACGTTGCGCGGCATCGACTGCGAGGCGAGCGTGGATAGCGGCGCCTATTCCGCCTATCCC
TTCTCCGCGTGCCTTGAGGCCGCGCAGGTGGCGAGCATCCTGCCCGGCCCCTACGACTTTCCCGCCTACCGCTGCCGCAC
CTGGTCGGTGGCCACCAACAAGTGCCCCATCCTGCCCTATCGCGGCGTGGCGCGCACCGGCGTGTGCTTCGCACTGGAAG
TGGCGCTGGATGCGCTGGCTGCGGAGCTGGGCCTTGCCCCCGAAGTGGTGCGGCTGAAGAACCTCGTGCGGCCCGAGCAG
ATGCCGTTCGACAACATCACCAAGAAGCATTTCGACAGCGGCGACTATCCCCAGGCGCTCCATCGCGCCCTCGACGCCAT
CAGGGCGGATGCGGTGCGCGCGCGCCAGACGGCGGGCGAGGCGGATGGCCGGCGCATCGGCCTCGGCCTCTCCATCTATT
GCGAGCAGGCGGCGCACGGCACCTCGGTCTATTCCGGTTGGGGCATTCCCATGGTGCCCGGCCACGAGCAGGCCGGCGCA
CGCCTCACCCCCGACGGCGGGCTGGAACTGCGCATCGGCGCCCATTCCCACGGCCAGGGGCTGGAGACCACGCTGGCCCA
GGTGGCGCACGAAATCCTCGGCATTCCGGTCGCCCGCACCCGGCTGGTGCACGGCGACACCGCCATGACTCCCTATTCCA
CGGGAAGCTGGGGCTCGCGGGTGATGGTGATGGCGGGCGGGGCGGTGGCCACCGCCTGCACGGAACTCGCCGAGCGTGTC
CGGCGCATCGGCGCCCACATGCTGCAGGCGCCCGTGGATCAGGTGCGTCTCGAAAACCGGCGCGTGGTCGGCCCGGCGGG
CGATGTGACCATCAGCCAGATCGCCCATACCTGGTACCGCCGCCCGCAGGACCTGCCGGCGGACGTGGATCCCCACGGGC
TGGAAGTCACCGCCGGCTACAAGCCGCAGCGCGACAGTGGCACCTTCAGCTATGCCGCCCATGCGGTGGTGGTGGCGGTG
GATCCGGAGCTGGGCGAGGTGGAGATCCTCGACTACGTCATCGTGGAAGATGGCGGCACGCTGGTGAATCCCATGGTGGT
GGACGGGCAGATCCTCGGCGGCCTCGCCCAGGGCATCGGCACCGCGCTTTACGAGGAAATGCCCTTCGACAGCTCCGGCC
AGCCCCTGGCATCGACGCTGGCGGACTATCTGCTGCCCGGCGCGCCGGAAGTGCCCCTGCCCTTCATCGATCATATGGCG
ACGCCCTCGCCCTACACGACATTCGGCGTGAAGGGCATCGGCGAAGGCGGTGCCATCGCGCCGCCGGCGGCCATCGCCAA
CGCCATCAACGACGCGCTGCGCCCGCTGGGAAGCGAGATGCTGCGCGCGCCCGTCACCCCGCGCCGCATCGTCGAGAGCG
TGCTTGCGGCCCGCGCCAGCCGCAGGAGCGCCGCATGA

Upstream 100 bases:

>100_bases
CCATCGCCGGCGCCAACCACTTCTCCATCCTCGACGAATTGCGCCGCCCCGACGGCCAGCTGGTGCGCGCCGCCCTCGAC
CTGATGCCGGGAGCCGCCGC

Downstream 100 bases:

>100_bases
AGCCCGCGCCCTTCCGCCTGGAGCGTCCGCGCGACATCGCCGGTGCCACGGCTCTCCTCGCCACCGGCGGCGACGGGGCG
AAGGCCATGGCCGGCTCGCA

Product: molybdopterin binding aldehyde oxidase and xanthine dehydrogenase

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 785; Mature: 784

Protein sequence:

>785_residues
MSETQMHEGVGARLPRKEDDRLMRGRGQFIADIRMTGMQDVAFVRSPLAHARICAIHVPDDLKGRVFTAADLDGVKPIRA
VSGLPGFKVSEQPVLALGKVRQVGELIAICVADTRAEAEDMAARVELDLEELPALHDMLEARKPGARLVHEHWGDNVFLE
SLVNINIEAAFDAPVKVSRTISTARQCMAPIEGRGAIIHFDHRSDQLVVHTASQMPHIVRSGLSECLSMEEGQIRIISPD
VGGGFGYKAILLAEEVCLGWLAQKLRRPVRWLEDRREHLTANANCREHHYEITLYAERDGTLRGIDCEASVDSGAYSAYP
FSACLEAAQVASILPGPYDFPAYRCRTWSVATNKCPILPYRGVARTGVCFALEVALDALAAELGLAPEVVRLKNLVRPEQ
MPFDNITKKHFDSGDYPQALHRALDAIRADAVRARQTAGEADGRRIGLGLSIYCEQAAHGTSVYSGWGIPMVPGHEQAGA
RLTPDGGLELRIGAHSHGQGLETTLAQVAHEILGIPVARTRLVHGDTAMTPYSTGSWGSRVMVMAGGAVATACTELAERV
RRIGAHMLQAPVDQVRLENRRVVGPAGDVTISQIAHTWYRRPQDLPADVDPHGLEVTAGYKPQRDSGTFSYAAHAVVVAV
DPELGEVEILDYVIVEDGGTLVNPMVVDGQILGGLAQGIGTALYEEMPFDSSGQPLASTLADYLLPGAPEVPLPFIDHMA
TPSPYTTFGVKGIGEGGAIAPPAAIANAINDALRPLGSEMLRAPVTPRRIVESVLAARASRRSAA

Sequences:

>Translated_785_residues
MSETQMHEGVGARLPRKEDDRLMRGRGQFIADIRMTGMQDVAFVRSPLAHARICAIHVPDDLKGRVFTAADLDGVKPIRA
VSGLPGFKVSEQPVLALGKVRQVGELIAICVADTRAEAEDMAARVELDLEELPALHDMLEARKPGARLVHEHWGDNVFLE
SLVNINIEAAFDAPVKVSRTISTARQCMAPIEGRGAIIHFDHRSDQLVVHTASQMPHIVRSGLSECLSMEEGQIRIISPD
VGGGFGYKAILLAEEVCLGWLAQKLRRPVRWLEDRREHLTANANCREHHYEITLYAERDGTLRGIDCEASVDSGAYSAYP
FSACLEAAQVASILPGPYDFPAYRCRTWSVATNKCPILPYRGVARTGVCFALEVALDALAAELGLAPEVVRLKNLVRPEQ
MPFDNITKKHFDSGDYPQALHRALDAIRADAVRARQTAGEADGRRIGLGLSIYCEQAAHGTSVYSGWGIPMVPGHEQAGA
RLTPDGGLELRIGAHSHGQGLETTLAQVAHEILGIPVARTRLVHGDTAMTPYSTGSWGSRVMVMAGGAVATACTELAERV
RRIGAHMLQAPVDQVRLENRRVVGPAGDVTISQIAHTWYRRPQDLPADVDPHGLEVTAGYKPQRDSGTFSYAAHAVVVAV
DPELGEVEILDYVIVEDGGTLVNPMVVDGQILGGLAQGIGTALYEEMPFDSSGQPLASTLADYLLPGAPEVPLPFIDHMA
TPSPYTTFGVKGIGEGGAIAPPAAIANAINDALRPLGSEMLRAPVTPRRIVESVLAARASRRSAA
>Mature_784_residues
SETQMHEGVGARLPRKEDDRLMRGRGQFIADIRMTGMQDVAFVRSPLAHARICAIHVPDDLKGRVFTAADLDGVKPIRAV
SGLPGFKVSEQPVLALGKVRQVGELIAICVADTRAEAEDMAARVELDLEELPALHDMLEARKPGARLVHEHWGDNVFLES
LVNINIEAAFDAPVKVSRTISTARQCMAPIEGRGAIIHFDHRSDQLVVHTASQMPHIVRSGLSECLSMEEGQIRIISPDV
GGGFGYKAILLAEEVCLGWLAQKLRRPVRWLEDRREHLTANANCREHHYEITLYAERDGTLRGIDCEASVDSGAYSAYPF
SACLEAAQVASILPGPYDFPAYRCRTWSVATNKCPILPYRGVARTGVCFALEVALDALAAELGLAPEVVRLKNLVRPEQM
PFDNITKKHFDSGDYPQALHRALDAIRADAVRARQTAGEADGRRIGLGLSIYCEQAAHGTSVYSGWGIPMVPGHEQAGAR
LTPDGGLELRIGAHSHGQGLETTLAQVAHEILGIPVARTRLVHGDTAMTPYSTGSWGSRVMVMAGGAVATACTELAERVR
RIGAHMLQAPVDQVRLENRRVVGPAGDVTISQIAHTWYRRPQDLPADVDPHGLEVTAGYKPQRDSGTFSYAAHAVVVAVD
PELGEVEILDYVIVEDGGTLVNPMVVDGQILGGLAQGIGTALYEEMPFDSSGQPLASTLADYLLPGAPEVPLPFIDHMAT
PSPYTTFGVKGIGEGGAIAPPAAIANAINDALRPLGSEMLRAPVTPRRIVESVLAARASRRSAA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI71773480, Length=752, Percent_Identity=23.1382978723404, Blast_Score=129, Evalue=1e-29,
Organism=Homo sapiens, GI91823271, Length=803, Percent_Identity=23.785803237858, Blast_Score=122, Evalue=2e-27,
Organism=Escherichia coli, GI1789230, Length=773, Percent_Identity=28.0724450194049, Blast_Score=215, Evalue=1e-56,
Organism=Escherichia coli, GI1789246, Length=827, Percent_Identity=25.1511487303507, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1786478, Length=620, Percent_Identity=24.1935483870968, Blast_Score=93, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24647193, Length=743, Percent_Identity=23.8223418573351, Blast_Score=116, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 84609; Mature: 84477

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETQMHEGVGARLPRKEDDRLMRGRGQFIADIRMTGMQDVAFVRSPLAHARICAIHVPD
CCCCCHHCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCEEEEEEECCC
DLKGRVFTAADLDGVKPIRAVSGLPGFKVSEQPVLALGKVRQVGELIAICVADTRAEAED
CCCCCEEEECCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
MAARVELDLEELPALHDMLEARKPGARLVHEHWGDNVFLESLVNINIEAAFDAPVKVSRT
HHHHEECCHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHH
ISTARQCMAPIEGRGAIIHFDHRSDQLVVHTASQMPHIVRSGLSECLSMEEGQIRIISPD
HHHHHHHHCCCCCCCEEEEECCCCCEEEEEECHHCHHHHHHHHHHHHCCCCCCEEEECCC
VGGGFGYKAILLAEEVCLGWLAQKLRRPVRWLEDRREHLTANANCREHHYEITLYAERDG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCC
TLRGIDCEASVDSGAYSAYPFSACLEAAQVASILPGPYDFPAYRCRTWSVATNKCPILPY
CEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCC
RGVARTGVCFALEVALDALAAELGLAPEVVRLKNLVRPEQMPFDNITKKHFDSGDYPQAL
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHH
HRALDAIRADAVRARQTAGEADGRRIGLGLSIYCEQAAHGTSVYSGWGIPMVPGHEQAGA
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEECCCCCCCCEECCCCCCCCCCCCCCCC
RLTPDGGLELRIGAHSHGQGLETTLAQVAHEILGIPVARTRLVHGDTAMTPYSTGSWGSR
EECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCCCCCE
VMVMAGGAVATACTELAERVRRIGAHMLQAPVDQVRLENRRVVGPAGDVTISQIAHTWYR
EEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEECCCCCHHHHHHHHHHHC
RPQDLPADVDPHGLEVTAGYKPQRDSGTFSYAAHAVVVAVDPELGEVEILDYVIVEDGGT
CCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEEEEEECCCCCCEEEEEEEEEECCCC
LVNPMVVDGQILGGLAQGIGTALYEEMPFDSSGQPLASTLADYLLPGAPEVPLPFIDHMA
EECCEEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHCC
TPSPYTTFGVKGIGEGGAIAPPAAIANAINDALRPLGSEMLRAPVTPRRIVESVLAARAS
CCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RRSAA
HCCCC
>Mature Secondary Structure 
SETQMHEGVGARLPRKEDDRLMRGRGQFIADIRMTGMQDVAFVRSPLAHARICAIHVPD
CCCCHHCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCHHHHHHHCCCCCEEEEEEECCC
DLKGRVFTAADLDGVKPIRAVSGLPGFKVSEQPVLALGKVRQVGELIAICVADTRAEAED
CCCCCEEEECCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHH
MAARVELDLEELPALHDMLEARKPGARLVHEHWGDNVFLESLVNINIEAAFDAPVKVSRT
HHHHEECCHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHH
ISTARQCMAPIEGRGAIIHFDHRSDQLVVHTASQMPHIVRSGLSECLSMEEGQIRIISPD
HHHHHHHHCCCCCCCEEEEECCCCCEEEEEECHHCHHHHHHHHHHHHCCCCCCEEEECCC
VGGGFGYKAILLAEEVCLGWLAQKLRRPVRWLEDRREHLTANANCREHHYEITLYAERDG
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEECCC
TLRGIDCEASVDSGAYSAYPFSACLEAAQVASILPGPYDFPAYRCRTWSVATNKCPILPY
CEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCC
RGVARTGVCFALEVALDALAAELGLAPEVVRLKNLVRPEQMPFDNITKKHFDSGDYPQAL
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCHHHH
HRALDAIRADAVRARQTAGEADGRRIGLGLSIYCEQAAHGTSVYSGWGIPMVPGHEQAGA
HHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEECCCCCCCCEECCCCCCCCCCCCCCCC
RLTPDGGLELRIGAHSHGQGLETTLAQVAHEILGIPVARTRLVHGDTAMTPYSTGSWGSR
EECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCCCCCCCE
VMVMAGGAVATACTELAERVRRIGAHMLQAPVDQVRLENRRVVGPAGDVTISQIAHTWYR
EEEEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEECCCCCHHHHHHHHHHHC
RPQDLPADVDPHGLEVTAGYKPQRDSGTFSYAAHAVVVAVDPELGEVEILDYVIVEDGGT
CCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEEEEEEECCCCCCEEEEEEEEEECCCC
LVNPMVVDGQILGGLAQGIGTALYEEMPFDSSGQPLASTLADYLLPGAPEVPLPFIDHMA
EECCEEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHCC
TPSPYTTFGVKGIGEGGAIAPPAAIANAINDALRPLGSEMLRAPVTPRRIVESVLAARAS
CCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
RRSAA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]