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The map label for this gene is cutS [H]

Identifier: 154244598

GI number: 154244598

Start: 726254

End: 727471

Strand: Reverse

Name: cutS [H]

Synonym: Xaut_0646

Alternate gene names: 154244598

Gene position: 727471-726254 (Counterclockwise)

Preceding gene: 154244599

Following gene: 154244597

Centisome position: 13.7

GC content: 72.41

Gene sequence:

>1218_bases
ATGAACGCCCTGCCCCGGCCGGAAGGCACAGCCCTTGGCGCCTCGCCCATGATCACCCTCACCCTCAACGGCCGCTCCGT
CGCTGCGACGGCGGAAGCGCGCACCAATCTCGCTGATCTGGTGCGGGACACGCTGAACCTCACCGGCACCCACATTGGCT
GCGAGCATGGGGTGTGCGGCGCCTGCACCATCCTGGTGGACGGCGAGCCGGCCCGCGCCTGCATCTCGTTTGCCGCCGCC
TGCCAGGGCGCGGACGTGGTCACCATCGAGGGGCTCGACGATGACGCGGTGACCGCAGAGCTGCGCGCCGCCTTCAATCG
TGAGCACGCCCTGCAATGCGGTTTCTGCACGCCGGGCATGCTGGTCTCGGCCCGCGACCTGGTGCTGCGCCTGCCGGAAG
CGGACGAGGCGCGCATCCGCCTCGGTCTTGCGGGCAACCTGTGCCGCTGCACGGGTTATGCCGGCATCGTCAAGGCGGTG
GCCTCGGTCATCGCCGCGCGGCGGGCGCAGGGCATCGGCCCGCTTACGGCCGAACGGCGGCTCGGGCCGGTGGGCGCGCG
GGCCGGCGGGGCGACGGCAATCGCCGTTCCACTGGCGAACGTGGCCGCCCTCGCAGCGCCGGCTGCGGAACCACTCGCCC
TCGGCGAAACCTTCATCCCCGCCAACAGCTTCGATCAGGGCTTTGAGGTACCGTTCCCGCCCGCCGACGTTTTCGCCTTC
TTCGGCAGGATCGAGGACGTGGCGGCCTGCCTGCCCGGCGCGGTCATCGACGCCATGCCGTCCGCCGATCTGGTGGAGGG
CGGCATGCGGGTGAAGCTCGGCCCCATCGGCACCACCTTCCGCGGCACCGCCCGCATCCGCCGCGACGAGGCCACCTCCA
GCGGCACCATCCACGGCGCCGGAGGGGACGGCCGCTCGCGCACCGAGGGCGAGATCCGCTATCGCGTCCTGCCCGGCACG
ACCCCCGGCTCGGCCTGCGTGGCGCTCAGCGTGGGCTACACGCTGAAAGGCCCGCTCGCCCAGTTCGGCCGGCCGGGCCT
CGTGCGCGAGGTGGCGGGCCGGCTCATCGCCGATTTCGCCGCAAATCTTGAGGCCCGCCTTTCCGGCGCGCCGGCGCCGG
CGGCGACAGGCCCCGGCCTCAACCCGCTCAAGCTGCTGACAGCCCTGATTTCCCAAAAGCTCGGCGCCCTGTGGCACCGC
ATCCGCCCCGCTTCCTGA

Upstream 100 bases:

>100_bases
CCGGCATGGACGATGCGGTCGACCGCCACGTGCATGTGGAGGTGCTGCGCCGCGCCGCTGCGCAGGCGGCGAACCTCTTC
ACCGAGACGCGGAGCGCCGC

Downstream 100 bases:

>100_bases
CCCTGACTGCCCAATGAGACTGGAGACCATCATGATGATTTCGCGCAGGACGACACTCGCGGCCCTCGCCTTCAGCCTCC
TCGCCGGCACGGCGATGGCC

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MNALPRPEGTALGASPMITLTLNGRSVAATAEARTNLADLVRDTLNLTGTHIGCEHGVCGACTILVDGEPARACISFAAA
CQGADVVTIEGLDDDAVTAELRAAFNREHALQCGFCTPGMLVSARDLVLRLPEADEARIRLGLAGNLCRCTGYAGIVKAV
ASVIAARRAQGIGPLTAERRLGPVGARAGGATAIAVPLANVAALAAPAAEPLALGETFIPANSFDQGFEVPFPPADVFAF
FGRIEDVAACLPGAVIDAMPSADLVEGGMRVKLGPIGTTFRGTARIRRDEATSSGTIHGAGGDGRSRTEGEIRYRVLPGT
TPGSACVALSVGYTLKGPLAQFGRPGLVREVAGRLIADFAANLEARLSGAPAPAATGPGLNPLKLLTALISQKLGALWHR
IRPAS

Sequences:

>Translated_405_residues
MNALPRPEGTALGASPMITLTLNGRSVAATAEARTNLADLVRDTLNLTGTHIGCEHGVCGACTILVDGEPARACISFAAA
CQGADVVTIEGLDDDAVTAELRAAFNREHALQCGFCTPGMLVSARDLVLRLPEADEARIRLGLAGNLCRCTGYAGIVKAV
ASVIAARRAQGIGPLTAERRLGPVGARAGGATAIAVPLANVAALAAPAAEPLALGETFIPANSFDQGFEVPFPPADVFAF
FGRIEDVAACLPGAVIDAMPSADLVEGGMRVKLGPIGTTFRGTARIRRDEATSSGTIHGAGGDGRSRTEGEIRYRVLPGT
TPGSACVALSVGYTLKGPLAQFGRPGLVREVAGRLIADFAANLEARLSGAPAPAATGPGLNPLKLLTALISQKLGALWHR
IRPAS
>Mature_405_residues
MNALPRPEGTALGASPMITLTLNGRSVAATAEARTNLADLVRDTLNLTGTHIGCEHGVCGACTILVDGEPARACISFAAA
CQGADVVTIEGLDDDAVTAELRAAFNREHALQCGFCTPGMLVSARDLVLRLPEADEARIRLGLAGNLCRCTGYAGIVKAV
ASVIAARRAQGIGPLTAERRLGPVGARAGGATAIAVPLANVAALAAPAAEPLALGETFIPANSFDQGFEVPFPPADVFAF
FGRIEDVAACLPGAVIDAMPSADLVEGGMRVKLGPIGTTFRGTARIRRDEATSSGTIHGAGGDGRSRTEGEIRYRVLPGT
TPGSACVALSVGYTLKGPLAQFGRPGLVREVAGRLIADFAANLEARLSGAPAPAATGPGLNPLKLLTALISQKLGALWHR
IRPAS

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=91, Percent_Identity=39.5604395604396, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI91823271, Length=150, Percent_Identity=34, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1786480, Length=158, Percent_Identity=37.3417721518987, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1789232, Length=145, Percent_Identity=39.3103448275862, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17540638, Length=156, Percent_Identity=37.8205128205128, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17539860, Length=156, Percent_Identity=34.6153846153846, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32566215, Length=156, Percent_Identity=35.2564102564103, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI17737937, Length=161, Percent_Identity=29.1925465838509, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24647199, Length=136, Percent_Identity=31.6176470588235, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24647201, Length=163, Percent_Identity=30.0613496932515, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24647197, Length=160, Percent_Identity=28.75, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24647195, Length=160, Percent_Identity=28.75, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24647193, Length=158, Percent_Identity=29.746835443038, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 41406; Mature: 41406

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNALPRPEGTALGASPMITLTLNGRSVAATAEARTNLADLVRDTLNLTGTHIGCEHGVCG
CCCCCCCCCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHHHCCCCEECCCCCCCE
ACTILVDGEPARACISFAAACQGADVVTIEGLDDDAVTAELRAAFNREHALQCGFCTPGM
EEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCEEECCCCCCH
LVSARDLVLRLPEADEARIRLGLAGNLCRCTGYAGIVKAVASVIAARRAQGIGPLTAERR
HEECCHHEEECCCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHC
LGPVGARAGGATAIAVPLANVAALAAPAAEPLALGETFIPANSFDQGFEVPFPPADVFAF
CCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCHHCCCEECCCCCCCCCCCCCCCHHHHHHH
FGRIEDVAACLPGAVIDAMPSADLVEGGMRVKLGPIGTTFRGTARIRRDEATSSGTIHGA
HHHHHHHHHHCCCHHHHCCCCHHHHCCCCEEEECCCCCCCCCCCEEECCCCCCCCEEECC
GGDGRSRTEGEIRYRVLPGTTPGSACVALSVGYTLKGPLAQFGRPGLVREVAGRLIADFA
CCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCEECCCHHHHCCCCHHHHHHHHHHHHHH
ANLEARLSGAPAPAATGPGLNPLKLLTALISQKLGALWHRIRPAS
HCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNALPRPEGTALGASPMITLTLNGRSVAATAEARTNLADLVRDTLNLTGTHIGCEHGVCG
CCCCCCCCCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHHHCCCCEECCCCCCCE
ACTILVDGEPARACISFAAACQGADVVTIEGLDDDAVTAELRAAFNREHALQCGFCTPGM
EEEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCCEEECCCCCCH
LVSARDLVLRLPEADEARIRLGLAGNLCRCTGYAGIVKAVASVIAARRAQGIGPLTAERR
HEECCHHEEECCCCCCCEEEEECCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHHC
LGPVGARAGGATAIAVPLANVAALAAPAAEPLALGETFIPANSFDQGFEVPFPPADVFAF
CCCCCCCCCCCEEEEHHHHHHHHHHCCCCCCHHCCCEECCCCCCCCCCCCCCCHHHHHHH
FGRIEDVAACLPGAVIDAMPSADLVEGGMRVKLGPIGTTFRGTARIRRDEATSSGTIHGA
HHHHHHHHHHCCCHHHHCCCCHHHHCCCCEEEECCCCCCCCCCCEEECCCCCCCCEEECC
GGDGRSRTEGEIRYRVLPGTTPGSACVALSVGYTLKGPLAQFGRPGLVREVAGRLIADFA
CCCCCCCCCCEEEEEEECCCCCCCEEEEEEECCEECCCHHHHCCCCHHHHHHHHHHHHHH
ANLEARLSGAPAPAATGPGLNPLKLLTALISQKLGALWHRIRPAS
HCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]