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The map label for this gene is hipA [C]

Identifier: 154244511

GI number: 154244511

Start: 626952

End: 628814

Strand: Reverse

Name: hipA [C]

Synonym: Xaut_0556

Alternate gene names: 154244511

Gene position: 628814-626952 (Counterclockwise)

Preceding gene: 154244512

Following gene: 154244507

Centisome position: 11.84

GC content: 65.54

Gene sequence:

>1863_bases
GTGACATACGCGAAAGTTAGAATTTTGCCCCTTCACCTCGTAGGCGAGACCATCGACAAGACCCGGAGCCACTACCTGGC
CGAGACAGGCCGGCTGGTGCAGCTCATGCGCGGTATCTATGTCGATGCCGGGGATGATGCTGACGCGACAGTCACGCGGC
ACGCTGTCCGCATTGCCCACTATCTCTATCCACGAGCCTACCTGTCCGGCGCAAGCGCCGTGCTGCTCGGCCCGACCCGC
GATGGCCGCCTTTTCCTGAGCGGGCGACGCATCCAGCGCACCCGTCTGCGGTCGCTGGAAATCATCCAGAATGCTGCGCC
TGAACATCCTTCGGTCGCGCCCGCCATTATCGATGACGGTATGGGCGAATTCCGGATCGACGTGTCCTCGATCAGGCAGC
GTTTCCTGGAGGCTTTCCGGATCAGGAGCGAGCATGCCGCGGCGCTCGACGAAACGATGCGGGAGCAAATCGCGCAGCGT
CTGATCGAGGAATATGGAACGCCGCAGGGCGCTGCCGACGCGGTTTGGACTCTTGCCCGCGAGAATCAATGGTACCGCGA
AGGCGAACACGCCGAACGATTTCTCCTGCGCCGGCCAGCCGCCGCGCCGGTGCGGAACGAGGCTGCGCTCGATCTTACGG
TCGCATGGCACGGCGCGCCGGTCGGGCAACTGACCCATGACGGCTTCGAGTGGCGCTGGCGCGATGAGGACTGGCACGGT
CCACCCCTGATCCGGCAGACGACCCCCGGCAAGCTGCCGCCCTTTATCGTCTCCCTGCTGCCGGAAGGCTGGCTTGAGTC
CGTGCTTCACGACCGCGACGAACGCGCGCTCCTGAAATCCGGCAGGCGCTACATGTCGAATATCACGATCGCCGAGCGCC
CCAGCGAGCTTGCCAGCCTGCCGGCTGACGTCCTGACAACGCCGCTGGCGCGCTATTCAGAGGACGGCGTCTTCACCGGG
CGGTACGCCGGCCCCGGACGCGGCCCGATCGAAGAGAGCTTCGAACGCAATCTGGCCGCGATTTTCGCAAGCAGCGAAAC
GCCGCGCCTTTCGGGCATCCAGATTAAAGCCCCGATGTTCCTCGGCCCGGACGGCACCCTGACGGCCAGCACAAAAGAGC
CCTTCACGCATATTCTCAAACCCGCCGGCACCAGTGGCTTTGAAATCCTCCCCGTGGTCGAATGGCAGGCGCTCGCCCTC
GGCGCGGCGGCGGGCTTCGAGACGCCGGCCATGGCGCTTGTCCCCATGCCGGACGGCATGCCCCCGGCGCTGCTCGTCGA
GCGTTTCGACATCAGGAGCGGCGCCAACGACACGCGCCTGCTGGCGCTGGAGGATTTCTGCTCGGTCCTCGGCCTGCCCA
CCGAAGCCAAGTATGACGGGACCATGGAGCGCGTCGCCCGCGCCGTGCGGCCGCTGTCAACCGCACCTGACGAAGACCTG
CTCATCGTCTTCCGGCGCGCTCTGTTCGCGTGGCTGATCGCCGACGGCGACATGCATCTCAAAAATCTGGCGCTCCTAAA
GATCGCCGAACCCGGAAGCGACCATTTTACAAGCGTCCGCATGGCCCCGCTTTACGACGCGGTGACAACGCGCGTATTCC
CGCGGCTGGCGCGCGACCGCATGGCGCTCAAGCTCGCCGGCAAGGACGACCGCCTGCGCCGATCCGAATTCAGGGCCTTT
GCGGCGACAGCCGGCGTTAAGGCGGCGGCGGCCGACGAGGCCATCGACGAGATGACCCGCGCGCTCGGGGCTACTCTCGA
CGCCGCCACCCTTCCGGCGCTGCTGACAAACTCTCCGGTGGCGGTTGAAGCGGTCACCGAAATGCAGCGCCTTGTCAGGG
AGCGCATCGACAATCTGTCGTAA

Upstream 100 bases:

>100_bases
GGACCGATTCATTCCCGCTTTCTAACTTTCCCATATTTGAAATACGGGAAAGTTATAATTCCTTGACATTCACGCATTAA
ATCTGCTAACTTTATCGTAT

Downstream 100 bases:

>100_bases
AGCACCGGCTGCCGCCTGAGAAAGGCATCGCGGGCCCTGGACACCTCAAAATCCCGAAAAAGAACCGATCGGGATGCTGG
CAGAGCGGGCGAACGGTTTT

Product: HipA domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MTYAKVRILPLHLVGETIDKTRSHYLAETGRLVQLMRGIYVDAGDDADATVTRHAVRIAHYLYPRAYLSGASAVLLGPTR
DGRLFLSGRRIQRTRLRSLEIIQNAAPEHPSVAPAIIDDGMGEFRIDVSSIRQRFLEAFRIRSEHAAALDETMREQIAQR
LIEEYGTPQGAADAVWTLARENQWYREGEHAERFLLRRPAAAPVRNEAALDLTVAWHGAPVGQLTHDGFEWRWRDEDWHG
PPLIRQTTPGKLPPFIVSLLPEGWLESVLHDRDERALLKSGRRYMSNITIAERPSELASLPADVLTTPLARYSEDGVFTG
RYAGPGRGPIEESFERNLAAIFASSETPRLSGIQIKAPMFLGPDGTLTASTKEPFTHILKPAGTSGFEILPVVEWQALAL
GAAAGFETPAMALVPMPDGMPPALLVERFDIRSGANDTRLLALEDFCSVLGLPTEAKYDGTMERVARAVRPLSTAPDEDL
LIVFRRALFAWLIADGDMHLKNLALLKIAEPGSDHFTSVRMAPLYDAVTTRVFPRLARDRMALKLAGKDDRLRRSEFRAF
AATAGVKAAAADEAIDEMTRALGATLDAATLPALLTNSPVAVEAVTEMQRLVRERIDNLS

Sequences:

>Translated_620_residues
MTYAKVRILPLHLVGETIDKTRSHYLAETGRLVQLMRGIYVDAGDDADATVTRHAVRIAHYLYPRAYLSGASAVLLGPTR
DGRLFLSGRRIQRTRLRSLEIIQNAAPEHPSVAPAIIDDGMGEFRIDVSSIRQRFLEAFRIRSEHAAALDETMREQIAQR
LIEEYGTPQGAADAVWTLARENQWYREGEHAERFLLRRPAAAPVRNEAALDLTVAWHGAPVGQLTHDGFEWRWRDEDWHG
PPLIRQTTPGKLPPFIVSLLPEGWLESVLHDRDERALLKSGRRYMSNITIAERPSELASLPADVLTTPLARYSEDGVFTG
RYAGPGRGPIEESFERNLAAIFASSETPRLSGIQIKAPMFLGPDGTLTASTKEPFTHILKPAGTSGFEILPVVEWQALAL
GAAAGFETPAMALVPMPDGMPPALLVERFDIRSGANDTRLLALEDFCSVLGLPTEAKYDGTMERVARAVRPLSTAPDEDL
LIVFRRALFAWLIADGDMHLKNLALLKIAEPGSDHFTSVRMAPLYDAVTTRVFPRLARDRMALKLAGKDDRLRRSEFRAF
AATAGVKAAAADEAIDEMTRALGATLDAATLPALLTNSPVAVEAVTEMQRLVRERIDNLS
>Mature_619_residues
TYAKVRILPLHLVGETIDKTRSHYLAETGRLVQLMRGIYVDAGDDADATVTRHAVRIAHYLYPRAYLSGASAVLLGPTRD
GRLFLSGRRIQRTRLRSLEIIQNAAPEHPSVAPAIIDDGMGEFRIDVSSIRQRFLEAFRIRSEHAAALDETMREQIAQRL
IEEYGTPQGAADAVWTLARENQWYREGEHAERFLLRRPAAAPVRNEAALDLTVAWHGAPVGQLTHDGFEWRWRDEDWHGP
PLIRQTTPGKLPPFIVSLLPEGWLESVLHDRDERALLKSGRRYMSNITIAERPSELASLPADVLTTPLARYSEDGVFTGR
YAGPGRGPIEESFERNLAAIFASSETPRLSGIQIKAPMFLGPDGTLTASTKEPFTHILKPAGTSGFEILPVVEWQALALG
AAAGFETPAMALVPMPDGMPPALLVERFDIRSGANDTRLLALEDFCSVLGLPTEAKYDGTMERVARAVRPLSTAPDEDLL
IVFRRALFAWLIADGDMHLKNLALLKIAEPGSDHFTSVRMAPLYDAVTTRVFPRLARDRMALKLAGKDDRLRRSEFRAFA
ATAGVKAAAADEAIDEMTRALGATLDAATLPALLTNSPVAVEAVTEMQRLVRERIDNLS

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4dM [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 68478; Mature: 68347

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYAKVRILPLHLVGETIDKTRSHYLAETGRLVQLMRGIYVDAGDDADATVTRHAVRIAH
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHH
YLYPRAYLSGASAVLLGPTRDGRLFLSGRRIQRTRLRSLEIIQNAAPEHPSVAPAIIDDG
HHHHHHHHCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCC
MGEFRIDVSSIRQRFLEAFRIRSEHAAALDETMREQIAQRLIEEYGTPQGAADAVWTLAR
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ENQWYREGEHAERFLLRRPAAAPVRNEAALDLTVAWHGAPVGQLTHDGFEWRWRDEDWHG
CCCHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEECCCCCCC
PPLIRQTTPGKLPPFIVSLLPEGWLESVLHDRDERALLKSGRRYMSNITIAERPSELASL
CCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHCCCHHHHHC
PADVLTTPLARYSEDGVFTGRYAGPGRGPIEESFERNLAAIFASSETPRLSGIQIKAPMF
CHHHHHCCHHHHCCCCEEECCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCCEEEECCEE
LGPDGTLTASTKEPFTHILKPAGTSGFEILPVVEWQALALGAAAGFETPAMALVPMPDGM
ECCCCCEECCCCCHHHHHHCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCEEEEECCCCC
PPALLVERFDIRSGANDTRLLALEDFCSVLGLPTEAKYDGTMERVARAVRPLSTAPDEDL
CHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCHH
LIVFRRALFAWLIADGDMHLKNLALLKIAEPGSDHFTSVRMAPLYDAVTTRVFPRLARDR
HHHHHHHHHHHHHCCCCCEECCEEEEEEECCCCCCHHEEEHHHHHHHHHHHHHHHHHHCC
MALKLAGKDDRLRRSEFRAFAATAGVKAAAADEAIDEMTRALGATLDAATLPALLTNSPV
EEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCH
AVEAVTEMQRLVRERIDNLS
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TYAKVRILPLHLVGETIDKTRSHYLAETGRLVQLMRGIYVDAGDDADATVTRHAVRIAH
CCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHH
YLYPRAYLSGASAVLLGPTRDGRLFLSGRRIQRTRLRSLEIIQNAAPEHPSVAPAIIDDG
HHHHHHHHCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCC
MGEFRIDVSSIRQRFLEAFRIRSEHAAALDETMREQIAQRLIEEYGTPQGAADAVWTLAR
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
ENQWYREGEHAERFLLRRPAAAPVRNEAALDLTVAWHGAPVGQLTHDGFEWRWRDEDWHG
CCCHHHCCHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEECCCCCCC
PPLIRQTTPGKLPPFIVSLLPEGWLESVLHDRDERALLKSGRRYMSNITIAERPSELASL
CCCCCCCCCCCCCHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHCCCHHHHHC
PADVLTTPLARYSEDGVFTGRYAGPGRGPIEESFERNLAAIFASSETPRLSGIQIKAPMF
CHHHHHCCHHHHCCCCEEECCCCCCCCCCHHHHHHCCEEEEEECCCCCCCCCEEEECCEE
LGPDGTLTASTKEPFTHILKPAGTSGFEILPVVEWQALALGAAAGFETPAMALVPMPDGM
ECCCCCEECCCCCHHHHHHCCCCCCCCEEEEECCHHHHHHHHHCCCCCCCEEEEECCCCC
PPALLVERFDIRSGANDTRLLALEDFCSVLGLPTEAKYDGTMERVARAVRPLSTAPDEDL
CHHHHHHHHHHCCCCCCCEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCHH
LIVFRRALFAWLIADGDMHLKNLALLKIAEPGSDHFTSVRMAPLYDAVTTRVFPRLARDR
HHHHHHHHHHHHHCCCCCEECCEEEEEEECCCCCCHHEEEHHHHHHHHHHHHHHHHHHCC
MALKLAGKDDRLRRSEFRAFAATAGVKAAAADEAIDEMTRALGATLDAATLPALLTNSPV
EEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCH
AVEAVTEMQRLVRERIDNLS
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]