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The map label for this gene is cjaC [H]

Identifier: 153952126

GI number: 153952126

Start: 1122953

End: 1123708

Strand: Direct

Name: cjaC [H]

Synonym: JJD26997_1277

Alternate gene names: 153952126

Gene position: 1122953-1123708 (Clockwise)

Preceding gene: 153951346

Following gene: 153952328

Centisome position: 60.86

GC content: 30.03

Gene sequence:

>756_bases
ATGAAAAAAATATTTAGTGTTGTTTTAGTTGCCTTGGTCGGTTTATTTTTAAACGCTTGTAATGATTCTAAAAACAAAGA
ATCAAATGCAAGTGTAGAATTAAAGGTTGGAACCGCTCCAAATTATAAACCTTTTAATTATAAAGAAAATTCAAAACTTA
CAGGTTTTGATACTGATTTGGTTGAAGAGATTGCCAAAAAAAATGGTATTAAAATTGTTTGGATTGAAACCAATTTCGAT
GGATTGATTCCTGCTTTAAAAGCTGGCAAAATCGATATGATTGCCTCGTCTATGAGCGCAACGGATGAAAGAAGACAAAG
TGTTGATTTTACCAAACCTTACTATATAAGTAAAAATCTTTATCTTAAACTAAAAAACAACGACTCTCTTCAAACAAAAA
ATGATTTAGAAGGTAAAAAAATAGGAGTTCAACTAGGAACCTTGCAAGAAAATACTGCAAAAGCTATCAAAAATACACAA
GTGCAAAGCAATAAAGATTTAAATATAGCTGTTTTAGCACTAAAAAACAACAAAATCGATGCTATTGTCGCAGATGAAGA
TACGGCGAAAGGTTTTTTAGCTGAAAATCCAGAATTGGTAAGTTTCTACCAAGAAACAGATGGTGGTGAAGGCTTTAGTT
TTGCTTTTGATAAAAATAAACAAAAAGATATTATTGAAATATTTAACAAAGGCATAGATGAGGCAAAAACCGATGGATTT
TACGATACCTTGATCAAAAAATATGAATTAGAATAA

Upstream 100 bases:

>100_bases
AGGATTGCATACTTTAAATATTGTAAAAAGCAATCAGACTTAATTAAATATAAATTTAAAATAAGTATAATTTTAAAACA
TTTTATATCAAAGGAAGAAA

Downstream 100 bases:

>100_bases
GCGTGAAAATTCACGCTTATATAACTTAAACTTTCATTGTATTTTGTAAAATAGCATCTCATACAAATTGACTCTCATTG
ATTCTTTATAAAAAACTTTA

Product: cjaC protein

Products: ADP; phosphate; L-ornithine [Cytoplasm]; ADP; L-arginine [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: HBP; p29 [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MKKIFSVVLVALVGLFLNACNDSKNKESNASVELKVGTAPNYKPFNYKENSKLTGFDTDLVEEIAKKNGIKIVWIETNFD
GLIPALKAGKIDMIASSMSATDERRQSVDFTKPYYISKNLYLKLKNNDSLQTKNDLEGKKIGVQLGTLQENTAKAIKNTQ
VQSNKDLNIAVLALKNNKIDAIVADEDTAKGFLAENPELVSFYQETDGGEGFSFAFDKNKQKDIIEIFNKGIDEAKTDGF
YDTLIKKYELE

Sequences:

>Translated_251_residues
MKKIFSVVLVALVGLFLNACNDSKNKESNASVELKVGTAPNYKPFNYKENSKLTGFDTDLVEEIAKKNGIKIVWIETNFD
GLIPALKAGKIDMIASSMSATDERRQSVDFTKPYYISKNLYLKLKNNDSLQTKNDLEGKKIGVQLGTLQENTAKAIKNTQ
VQSNKDLNIAVLALKNNKIDAIVADEDTAKGFLAENPELVSFYQETDGGEGFSFAFDKNKQKDIIEIFNKGIDEAKTDGF
YDTLIKKYELE
>Mature_251_residues
MKKIFSVVLVALVGLFLNACNDSKNKESNASVELKVGTAPNYKPFNYKENSKLTGFDTDLVEEIAKKNGIKIVWIETNFD
GLIPALKAGKIDMIASSMSATDERRQSVDFTKPYYISKNLYLKLKNNDSLQTKNDLEGKKIGVQLGTLQENTAKAIKNTQ
VQSNKDLNIAVLALKNNKIDAIVADEDTAKGFLAENPELVSFYQETDGGEGFSFAFDKNKQKDIIEIFNKGIDEAKTDGF
YDTLIKKYELE

Specific function: Component of the high-affinity histidine permease, a binding-protein-dependent transport system. The other components are proteins hisQ, hisM, and hisP [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788649, Length=271, Percent_Identity=32.1033210332103, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1788648, Length=229, Percent_Identity=34.9344978165939, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788228, Length=253, Percent_Identity=28.8537549407115, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1787085, Length=257, Percent_Identity=29.9610894941634, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1787031, Length=237, Percent_Identity=29.535864978903, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1787088, Length=255, Percent_Identity=29.0196078431373, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 27975; Mature: 27975

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS01039 SBP_BACTERIAL_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIFSVVLVALVGLFLNACNDSKNKESNASVELKVGTAPNYKPFNYKENSKLTGFDTDL
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHH
VEEIAKKNGIKIVWIETNFDGLIPALKAGKIDMIASSMSATDERRQSVDFTKPYYISKNL
HHHHHHHCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCEE
YLKLKNNDSLQTKNDLEGKKIGVQLGTLQENTAKAIKNTQVQSNKDLNIAVLALKNNKID
EEEECCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCEE
AIVADEDTAKGFLAENPELVSFYQETDGGEGFSFAFDKNKQKDIIEIFNKGIDEAKTDGF
EEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHCCCH
YDTLIKKYELE
HHHHHHHHCCC
>Mature Secondary Structure
MKKIFSVVLVALVGLFLNACNDSKNKESNASVELKVGTAPNYKPFNYKENSKLTGFDTDL
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHH
VEEIAKKNGIKIVWIETNFDGLIPALKAGKIDMIASSMSATDERRQSVDFTKPYYISKNL
HHHHHHHCCCEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCEE
YLKLKNNDSLQTKNDLEGKKIGVQLGTLQENTAKAIKNTQVQSNKDLNIAVLALKNNKID
EEEECCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHCCCCCCCCCCEEEEEEEECCCEE
AIVADEDTAKGFLAENPELVSFYQETDGGEGFSFAFDKNKQKDIIEIFNKGIDEAKTDGF
EEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEEEECCCCCHHHHHHHHCCCCHHHCCCH
YDTLIKKYELE
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-ornithine [Periplasm]; H2O; ATP; L-arginine [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: ATP + L-ornithine [Periplasm] + H2O = ADP + phosphate + L-ornithine [Cytoplasm] ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] ATP + L-lysine [Periplasm] + H2O = ADP + phosphate + L-lysine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9192026; 9395059; 10688204 [H]