Click here to switch to the map view.

The map label for this gene is eda [H]

Identifier: 153951892

GI number: 153951892

Start: 1119749

End: 1120372

Strand: Direct

Name: eda [H]

Synonym: JJD26997_1272

Alternate gene names: 153951892

Gene position: 1119749-1120372 (Clockwise)

Preceding gene: 153951295

Following gene: 153951346

Centisome position: 60.69

GC content: 30.45

Gene sequence:

>624_bases
ATGCAAACAAAAGAAATTTTAGAAATTAGTAAAATCATTCCAGTAATTACGATTTACGATTTAAAAACAAGCGTTGATTT
AGCTAAAGCTTTACTAGATGGGGGTATTAGAATTTTAGAAATTACCCTAAGAACAAATAATGCAATCGAAGCAATCAAAC
TCATAGCAAACGAAGTTCCACAGGTTATCGTAGGTGCGGGAACTATTTTAAATTTTAAAATGCTAGAAGAAGTCAAAAAT
GCCGGTGCAAAATTTGCTATAAGCCCGGGTTTAAATTCTATTTTTGCAAAAGAAGCTCAAAATATAGATATAACACTAAT
TCCGGGTGTAGCAACAGCTAGTGAAATAATGTTAGCTCTTGAATTTAATTATCGAAACTTAAAGTTTTTTCCAGCTGAAG
CCTCTGGCGGCATAGCAATGTTAAAATCTTTAGCTGCTCCTTTTCACGAAGTGAAATTTTGTCCTACTGGCGGTATAAAT
TTAAACAATATGAAACATTATCTAAACTTAAATAATGTTTCTTGTATAGGTGGATCTTGGTTAAGCCCTAAAGAATTAAT
TTTAGAAAAAAAATGGGATAAAATTACTCAAATTACTAAACAAAGTTTAGAAAAAAGTTTATAA

Upstream 100 bases:

>100_bases
TGGCTGTGGCAGAGAGCTTTTTGCAGGGTTTAGAACGCAAAGTTCAAGCGCAGAAACGGGTGCTATGAGCTTTGGAGGAT
ATTTCAGTTAAGGAGAAAAA

Downstream 100 bases:

>100_bases
TTCTAATTGATAAAACATGATTTTTATGTAAATAATTATAGATAATTTTTAAATATAGGAGTTTATATACTTGCTTTAGA
TTTTAAAGCTTGATTTCAAA

Product: KHG/KDPG aldolase

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase; 2-keto-4-hydroxyglutarate aldolase; KHG-aldolase; 2-dehydro-3-deoxy-phosphogluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase; KDPG-aldolase; Phospho-2-dehydro-3-deoxygluconate aldolase; Phospho-2-keto-3-deoxygluconate aldolase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MQTKEILEISKIIPVITIYDLKTSVDLAKALLDGGIRILEITLRTNNAIEAIKLIANEVPQVIVGAGTILNFKMLEEVKN
AGAKFAISPGLNSIFAKEAQNIDITLIPGVATASEIMLALEFNYRNLKFFPAEASGGIAMLKSLAAPFHEVKFCPTGGIN
LNNMKHYLNLNNVSCIGGSWLSPKELILEKKWDKITQITKQSLEKSL

Sequences:

>Translated_207_residues
MQTKEILEISKIIPVITIYDLKTSVDLAKALLDGGIRILEITLRTNNAIEAIKLIANEVPQVIVGAGTILNFKMLEEVKN
AGAKFAISPGLNSIFAKEAQNIDITLIPGVATASEIMLALEFNYRNLKFFPAEASGGIAMLKSLAAPFHEVKFCPTGGIN
LNNMKHYLNLNNVSCIGGSWLSPKELILEKKWDKITQITKQSLEKSL
>Mature_207_residues
MQTKEILEISKIIPVITIYDLKTSVDLAKALLDGGIRILEITLRTNNAIEAIKLIANEVPQVIVGAGTILNFKMLEEVKN
AGAKFAISPGLNSIFAKEAQNIDITLIPGVATASEIMLALEFNYRNLKFFPAEASGGIAMLKSLAAPFHEVKFCPTGGIN
LNNMKHYLNLNNVSCIGGSWLSPKELILEKKWDKITQITKQSLEKSL

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. PARTICIPATES IN THE REGULATION OF THE INTRACELLULAR LEVEL OF GLYOXYLATE. [C]

COG id: COG0800

COG function: function code G; 2-keto-3-deoxy-6-phosphogluconate aldolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KHG/KDPG aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1788156, Length=186, Percent_Identity=50.5376344086022, Blast_Score=208, Evalue=2e-55,
Organism=Escherichia coli, GI48994954, Length=150, Percent_Identity=27.3333333333333, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000887
- InterPro:   IPR013785 [H]

Pfam domain/function: PF01081 Aldolase [H]

EC number: =4.1.3.16; =4.1.2.14 [H]

Molecular weight: Translated: 22652; Mature: 22652

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS00159 ALDOLASE_KDPG_KHG_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTKEILEISKIIPVITIYDLKTSVDLAKALLDGGIRILEITLRTNNAIEAIKLIANEVP
CCHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHCCEEEEEEEEECCCHHHHHHHHHHHCC
QVIVGAGTILNFKMLEEVKNAGAKFAISPGLNSIFAKEAQNIDITLIPGVATASEIMLAL
CEEECCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCCCEEEEECCCCCHHHEEEEE
EFNYRNLKFFPAEASGGIAMLKSLAAPFHEVKFCPTGGINLNNMKHYLNLNNVSCIGGSW
EECCCCEEEECCCCCCHHHHHHHHHCCHHHEEECCCCCCCCCCHHEEEECCCEEEECCCC
LSPKELILEKKWDKITQITKQSLEKSL
CCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQTKEILEISKIIPVITIYDLKTSVDLAKALLDGGIRILEITLRTNNAIEAIKLIANEVP
CCHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHCCEEEEEEEEECCCHHHHHHHHHHHCC
QVIVGAGTILNFKMLEEVKNAGAKFAISPGLNSIFAKEAQNIDITLIPGVATASEIMLAL
CEEECCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHCCCCEEEEECCCCCHHHEEEEE
EFNYRNLKFFPAEASGGIAMLKSLAAPFHEVKFCPTGGINLNNMKHYLNLNNVSCIGGSW
EECCCCEEEECCCCCCHHHHHHHHHCCHHHEEECCCCCCCCCCHHEEEECCCEEEECCCC
LSPKELILEKKWDKITQITKQSLEKSL
CCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8145647 [H]