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The map label for this gene is edd [H]

Identifier: 153951295

GI number: 153951295

Start: 1117937

End: 1119739

Strand: Direct

Name: edd [H]

Synonym: JJD26997_1271

Alternate gene names: 153951295

Gene position: 1117937-1119739 (Clockwise)

Preceding gene: 153951554

Following gene: 153951892

Centisome position: 60.59

GC content: 35.44

Gene sequence:

>1803_bases
ATGGTACAAAATAAACTAGAGCAAATTACAAAAAAAATTATAGAACGCAGTAAAAAAACAAGGAATGCTTATTTAGAGAG
AATTTATACCTATAAAGGCAAAATTCAAAAAAAAGATTTAGGCTGTGCTAATTTAGCCCATGCTTATGCAAGTATTCCTA
AACATATAAAAGAAAGAATTAAAGATAGCGAAACATTAAACTATGCTATAATTTCAGCTTACAATGATATGCTTTCGGCT
CACCAGCCTTTTAAAAACTACCCAGATATAATCAAAAAAGAAATTTTTAAGTATAACGCTTTTGCACAATTTGCAGGAGG
CACACCCGCTATGTGTGATGGTATCACTCAAGGCTATGAGGGTATGGAGCTTAGTCTTTTTTCAAGAGATGTGATTGCTA
TGAGTGTAGCCATAGCCCTTTCTCATAATGTTTTTGATGGGGCTTTTTATCTGGGTGTGTGTGATAAAATTGTTCCGGGT
CTTTTAATAGGAGCCTTAAGTTTTGGGCATTTGCCAAGTATTTTTATACCTTCAGGACCTATGACTAGTGGAATTTCTAA
TGATGAAAAATCTAAAACCAGACAACTTTTTGCTGAAGGTAAAATTTCTCGCGATAAATTACTCGAAAGCGAAATGAAAT
CTTACCACGATATCGGCACTTGCACCTTTTATGGCACAGCCAATTCAAATCAAATGATGATGGAATTTATGGGTTTGCAT
TTGCCAAATTCTGCTTTTATCAATCCAAATACCACCCTAAGAGAAGCTTTGGTAAAAGAAGCGGCTTCACATATGGTAAA
AAATAAAATTAAAGGCATAGGAGAACTTCTTAGTGAAAAAAATATTGTCAATGCCATAATAGGACTTATGGCAACGGGGG
GTTCGACTAATCATACTATTCACTTAAGTGCTATTGCTAGAGCAGCGGGCATTATTATAAATTGGGATGATTTTGGTGCT
ATTTCTAGCATCACTCCACTTTTAGCAAGAGTTTATCCTAATGGAAAAGCCGATGTAAATCAATTTGAAGCTTCTGGAGG
TATAGCTTTTATTATTCATGAGCTTTTAAAAGAGGGGTTATTACACGAAGATGCAGATACTATTATGGGTAAGGGTTTGG
AAGCTTACACCAAAAATCCATTCTTAATTGATGATAAAATTATCTATAAAGATGGAGTAAAAACAAGCAAAAATGAAAAT
ATATTAAGAAATATAGAAAATCCTTTTTCTAAAGATGGGGGAGTTAGAATTTTAAGGGGAAACATAGGCAGAGCGGTAAT
TAAAATTTCAGCCGTAAAAGAAGAACACCAAGTCATAAAAGCTCCAGCCTTAGTTTTTCACTCTCAACAAGAATTTTTAC
AAAGCTTTCAAAATGGGGAATTAGAAAAAGATTTTATCGCTGTTTTGCCCTATCAAGGACCTAGAGCAAATGGTATGCCA
GAACTTCACAAACTTACCCCGCCTTTGGGAATTTTACAAGATAGAGGTTTTAAGGTTGCTCTTGTTACAGATGGGAGAAT
GTCAGGGGCCTCAGGCAAAGTTCCAGCGGCTATACATATGAGTCCAGAAGCCTTGCTTGGAGGTAATATAGCAAAAATCA
AAAATGGGGATTTGCTTTTGCTTGACGCAAAAAATGGCACTCTTGAAATTTTAATCAGTGAAAAAGAATGGCAAGAAAGA
ACAGCCAATAAATTTGAAAGTCAAGAATTTTTTGGCTGTGGCAGAGAGCTTTTTGCAGGGTTTAGAACGCAAAGTTCAAG
CGCAGAAACGGGTGCTATGAGCTTTGGAGGATATTTCAGTTAA

Upstream 100 bases:

>100_bases
AAAATAAAGCTATCATTTAGAATTTTTATCTAAAATATAGCATAATTATTAAAATAACAACAAACTCTATCTAGTTCAAC
CTAGAAATAAGGAAAAAATA

Downstream 100 bases:

>100_bases
GGAGAAAAAATGCAAACAAAAGAAATTTTAGAAATTAGTAAAATCATTCCAGTAATTACGATTTACGATTTAAAAACAAG
CGTTGATTTAGCTAAAGCTT

Product: phosphogluconate dehydratase

Products: NA

Alternate protein names: 6-phosphogluconate dehydratase [H]

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MVQNKLEQITKKIIERSKKTRNAYLERIYTYKGKIQKKDLGCANLAHAYASIPKHIKERIKDSETLNYAIISAYNDMLSA
HQPFKNYPDIIKKEIFKYNAFAQFAGGTPAMCDGITQGYEGMELSLFSRDVIAMSVAIALSHNVFDGAFYLGVCDKIVPG
LLIGALSFGHLPSIFIPSGPMTSGISNDEKSKTRQLFAEGKISRDKLLESEMKSYHDIGTCTFYGTANSNQMMMEFMGLH
LPNSAFINPNTTLREALVKEAASHMVKNKIKGIGELLSEKNIVNAIIGLMATGGSTNHTIHLSAIARAAGIIINWDDFGA
ISSITPLLARVYPNGKADVNQFEASGGIAFIIHELLKEGLLHEDADTIMGKGLEAYTKNPFLIDDKIIYKDGVKTSKNEN
ILRNIENPFSKDGGVRILRGNIGRAVIKISAVKEEHQVIKAPALVFHSQQEFLQSFQNGELEKDFIAVLPYQGPRANGMP
ELHKLTPPLGILQDRGFKVALVTDGRMSGASGKVPAAIHMSPEALLGGNIAKIKNGDLLLLDAKNGTLEILISEKEWQER
TANKFESQEFFGCGRELFAGFRTQSSSAETGAMSFGGYFS

Sequences:

>Translated_600_residues
MVQNKLEQITKKIIERSKKTRNAYLERIYTYKGKIQKKDLGCANLAHAYASIPKHIKERIKDSETLNYAIISAYNDMLSA
HQPFKNYPDIIKKEIFKYNAFAQFAGGTPAMCDGITQGYEGMELSLFSRDVIAMSVAIALSHNVFDGAFYLGVCDKIVPG
LLIGALSFGHLPSIFIPSGPMTSGISNDEKSKTRQLFAEGKISRDKLLESEMKSYHDIGTCTFYGTANSNQMMMEFMGLH
LPNSAFINPNTTLREALVKEAASHMVKNKIKGIGELLSEKNIVNAIIGLMATGGSTNHTIHLSAIARAAGIIINWDDFGA
ISSITPLLARVYPNGKADVNQFEASGGIAFIIHELLKEGLLHEDADTIMGKGLEAYTKNPFLIDDKIIYKDGVKTSKNEN
ILRNIENPFSKDGGVRILRGNIGRAVIKISAVKEEHQVIKAPALVFHSQQEFLQSFQNGELEKDFIAVLPYQGPRANGMP
ELHKLTPPLGILQDRGFKVALVTDGRMSGASGKVPAAIHMSPEALLGGNIAKIKNGDLLLLDAKNGTLEILISEKEWQER
TANKFESQEFFGCGRELFAGFRTQSSSAETGAMSFGGYFS
>Mature_600_residues
MVQNKLEQITKKIIERSKKTRNAYLERIYTYKGKIQKKDLGCANLAHAYASIPKHIKERIKDSETLNYAIISAYNDMLSA
HQPFKNYPDIIKKEIFKYNAFAQFAGGTPAMCDGITQGYEGMELSLFSRDVIAMSVAIALSHNVFDGAFYLGVCDKIVPG
LLIGALSFGHLPSIFIPSGPMTSGISNDEKSKTRQLFAEGKISRDKLLESEMKSYHDIGTCTFYGTANSNQMMMEFMGLH
LPNSAFINPNTTLREALVKEAASHMVKNKIKGIGELLSEKNIVNAIIGLMATGGSTNHTIHLSAIARAAGIIINWDDFGA
ISSITPLLARVYPNGKADVNQFEASGGIAFIIHELLKEGLLHEDADTIMGKGLEAYTKNPFLIDDKIIYKDGVKTSKNEN
ILRNIENPFSKDGGVRILRGNIGRAVIKISAVKEEHQVIKAPALVFHSQQEFLQSFQNGELEKDFIAVLPYQGPRANGMP
ELHKLTPPLGILQDRGFKVALVTDGRMSGASGKVPAAIHMSPEALLGGNIAKIKNGDLLLLDAKNGTLEILISEKEWQER
TANKFESQEFFGCGRELFAGFRTQSSSAETGAMSFGGYFS

Specific function: KEY ENZYME IN THE ENTNER-DOUDOROFF PATHWAY. [C]

COG id: COG0129

COG function: function code EG; Dihydroxyacid dehydratase/phosphogluconate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ilvD/edd family [H]

Homologues:

Organism=Escherichia coli, GI1788157, Length=595, Percent_Identity=54.6218487394958, Blast_Score=698, Evalue=0.0,
Organism=Escherichia coli, GI48994964, Length=537, Percent_Identity=28.3054003724395, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI2367371, Length=472, Percent_Identity=30.5084745762712, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1786464, Length=485, Percent_Identity=29.2783505154639, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6322476, Length=482, Percent_Identity=30.9128630705394, Blast_Score=185, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004786
- InterPro:   IPR015928
- InterPro:   IPR000581
- InterPro:   IPR020558 [H]

Pfam domain/function: PF00920 ILVD_EDD [H]

EC number: =4.2.1.12 [H]

Molecular weight: Translated: 65841; Mature: 65841

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS00886 ILVD_EDD_1 ; PS00887 ILVD_EDD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQNKLEQITKKIIERSKKTRNAYLERIYTYKGKIQKKDLGCANLAHAYASIPKHIKERI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KDSETLNYAIISAYNDMLSAHQPFKNYPDIIKKEIFKYNAFAQFAGGTPAMCDGITQGYE
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
GMELSLFSRDVIAMSVAIALSHNVFDGAFYLGVCDKIVPGLLIGALSFGHLPSIFIPSGP
CCEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
MTSGISNDEKSKTRQLFAEGKISRDKLLESEMKSYHDIGTCTFYGTANSNQMMMEFMGLH
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCC
LPNSAFINPNTTLREALVKEAASHMVKNKIKGIGELLSEKNIVNAIIGLMATGGSTNHTI
CCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
HLSAIARAAGIIINWDDFGAISSITPLLARVYPNGKADVNQFEASGGIAFIIHELLKEGL
EHEEHHHHCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHCC
LHEDADTIMGKGLEAYTKNPFLIDDKIIYKDGVKTSKNENILRNIENPFSKDGGVRILRG
CCCCHHHHHHCCCHHHCCCCEEECCEEEEECCCCCCCCCHHHHHHCCCCCCCCCEEEEEC
NIGRAVIKISAVKEEHQVIKAPALVFHSQQEFLQSFQNGELEKDFIAVLPYQGPRANGMP
CCCEEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
ELHKLTPPLGILQDRGFKVALVTDGRMSGASGKVPAAIHMSPEALLGGNIAKIKNGDLLL
HHHHCCCCCHHHHCCCEEEEEEECCCCCCCCCCCCEEEECCCHHHHCCCEEEECCCCEEE
LDAKNGTLEILISEKEWQERTANKFESQEFFGCGRELFAGFRTQSSSAETGAMSFGGYFS
EECCCCEEEEEECCHHHHHHHHHHHCCHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVQNKLEQITKKIIERSKKTRNAYLERIYTYKGKIQKKDLGCANLAHAYASIPKHIKERI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
KDSETLNYAIISAYNDMLSAHQPFKNYPDIIKKEIFKYNAFAQFAGGTPAMCDGITQGYE
CCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCC
GMELSLFSRDVIAMSVAIALSHNVFDGAFYLGVCDKIVPGLLIGALSFGHLPSIFIPSGP
CCEEEHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCC
MTSGISNDEKSKTRQLFAEGKISRDKLLESEMKSYHDIGTCTFYGTANSNQMMMEFMGLH
CCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCC
LPNSAFINPNTTLREALVKEAASHMVKNKIKGIGELLSEKNIVNAIIGLMATGGSTNHTI
CCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
HLSAIARAAGIIINWDDFGAISSITPLLARVYPNGKADVNQFEASGGIAFIIHELLKEGL
EHEEHHHHCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHCC
LHEDADTIMGKGLEAYTKNPFLIDDKIIYKDGVKTSKNENILRNIENPFSKDGGVRILRG
CCCCHHHHHHCCCHHHCCCCEEECCEEEEECCCCCCCCCHHHHHHCCCCCCCCCEEEEEC
NIGRAVIKISAVKEEHQVIKAPALVFHSQQEFLQSFQNGELEKDFIAVLPYQGPRANGMP
CCCEEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCC
ELHKLTPPLGILQDRGFKVALVTDGRMSGASGKVPAAIHMSPEALLGGNIAKIKNGDLLL
HHHHCCCCCHHHHCCCEEEEEEECCCCCCCCCCCCEEEECCCHHHHCCCEEEECCCCEEE
LDAKNGTLEILISEKEWQERTANKFESQEFFGCGRELFAGFRTQSSSAETGAMSFGGYFS
EECCCCEEEEEECCHHHHHHHHHHHCCHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]