Click here to switch to the map view.

The map label for this gene is dsbD [H]

Identifier: 153951854

GI number: 153951854

Start: 941015

End: 942718

Strand: Direct

Name: dsbD [H]

Synonym: JJD26997_1067

Alternate gene names: 153951854

Gene position: 941015-942718 (Clockwise)

Preceding gene: 153950965

Following gene: 153952391

Centisome position: 51.0

GC content: 27.29

Gene sequence:

>1704_bases
ATGCGTATTTTTGGTATTATTTTATTAAGTATTTGTTTATGTTTTGCTTCTATATTGTCTTTGAATGAAGCTTTTAATGT
AAAGTCAAACTCCTACAATAACTCTATCTCAATCGATATTGAACTTGGAAAAGATATTTATCTTTATTCTAATAAAATTA
AATTATATATAAATGAAAAAGATATAAGTTCTTTGATTAATCTACCTCAAAGTTCTACAAGAGGCAATGAAAATGTTTAT
TATCGAAAATTAAATTTAGCTTTACCAAATTTATTACTAGAGCGCTTTGCAAAAAATAATACAAATTTAATCAAACTCGA
ATTTCAAGGCTGTTCTGAACAAGGCTTGTGTTACAATCCTCAAACTTGGTACTTTGATCTCATTTCTAAAAAAAATACTT
TTGAAATTTCAAAACCTTACAAAGCTCAAAAAACAGATAAAAAAACTAAAATCGAATCTGAAGAAAGCTCTATAGCAAAT
TTTTTAACAACAGATAACTTTTTTTGGATTTTGCTAAGTTTTTTTGGCTATGGACTTTTACTTTCCTTAACACCTTGTAT
TTTACCTATGATTCCGATTTTATCTTCTCTTATCATAGCAAAAAGTAATGCCAAATTTTCAAAAAAATATAGTTTTTTTC
TCTCTTTTATCTATGTTTTTTTCATGTCTTTAGCCTATGCTATTGCTGGAGTTATAGCAAGTTTTCTAGGAACAAGTATT
CAAGGAATTTTACAAAAACCTATTATTTTAATTCTTTTTGCTCTAATTTTCATAGCTTTTGCTTTTGCTATGTTTGGAGC
TTTTCGTTTTGAATTGCCATTAAGATTTCAAACCTTTATACATAAAAAAAGCGAAAAAGGAAAAGGAGTAGTAGGTATAG
CCATCATGGGATTTTTATCTGCTTTAATAGTAGGTCCTTGCGTAGCAGCTCCTTTGGCAGGTGCTTTAATTTATATAGCC
AATACAGGCAATGCTTTATTAGGTGGTAGTGCACTTTTTATCATGAGTTTTGGCATGGGTATACCTTTACTTTTCATAGG
CTTGGGATTAGGTTTTATCAAACCTGGTTTTTGGATGGAAAAAGTAAAAATTTTCTTTAGTTTTGTTATGTTAGCTATGG
CTATTTGGATACTTTCTAGAATTATTGAAGAAAATTACATTTTAATTGCCTATGGAATTTTAGGTGTATTTTTTAGTGTT
TTTATGGGAATTTTTGAAAAAAGTTTTGCAATAATTTCTAAAATTAAAAAAAGTATTTTGATTCTTATTTTAGCTTATTC
TCTAAGTATTTTCCTAGGGGGACTTTTTGGGGCTAAAAATTTCTTAAATCCTTTAAATTTCAATACTATATCTACTTCAA
AACCTGCTTTAAGCTATGATTATATCAACAATTTTGAACAATTAAAACAAGAGATACAAACAAGCATAAAGCCTATAATG
CTTGATTTTACTGCATCTTGGTGTGAAAATTGCAAACTTTTAGATGAATTAACCTTTAGCGATGAAAGAATCATACAAAA
AATGCAAAATTACAAACTTATCAAAGTGGATGTAAGCCAAAATAATAATGAACAAATTAAAACTATGAAAGAATTTAATG
TTTTTGGCCCACCTGTTTTAATTTTATTTGAAAATGGAAAAGAAAAATTAAAAATCACAGGTTTTATCAGTGCTGATGAT
TTATTAAAAAAACTAGAACCATGA

Upstream 100 bases:

>100_bases
TGCATTTTCAAACCTTATATAAAGTATTTAAAGCAAATTTACCATGATAAATTATAATTGAAGCCAAAAATAAAGGAAAA
AATAAGTTTTTAGGAAATTG

Downstream 100 bases:

>100_bases
AAATTTCAAACTTGCAAATTAAAAAAATTAAACTCTCTCATATCCCAAAATTGACACGAAACAATACATAAATGCTTAAA
AAATACTTACGATATAAGCT

Product: thiol:disulfide interchange protein DsbD

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MRIFGIILLSICLCFASILSLNEAFNVKSNSYNNSISIDIELGKDIYLYSNKIKLYINEKDISSLINLPQSSTRGNENVY
YRKLNLALPNLLLERFAKNNTNLIKLEFQGCSEQGLCYNPQTWYFDLISKKNTFEISKPYKAQKTDKKTKIESEESSIAN
FLTTDNFFWILLSFFGYGLLLSLTPCILPMIPILSSLIIAKSNAKFSKKYSFFLSFIYVFFMSLAYAIAGVIASFLGTSI
QGILQKPIILILFALIFIAFAFAMFGAFRFELPLRFQTFIHKKSEKGKGVVGIAIMGFLSALIVGPCVAAPLAGALIYIA
NTGNALLGGSALFIMSFGMGIPLLFIGLGLGFIKPGFWMEKVKIFFSFVMLAMAIWILSRIIEENYILIAYGILGVFFSV
FMGIFEKSFAIISKIKKSILILILAYSLSIFLGGLFGAKNFLNPLNFNTISTSKPALSYDYINNFEQLKQEIQTSIKPIM
LDFTASWCENCKLLDELTFSDERIIQKMQNYKLIKVDVSQNNNEQIKTMKEFNVFGPPVLILFENGKEKLKITGFISADD
LLKKLEP

Sequences:

>Translated_567_residues
MRIFGIILLSICLCFASILSLNEAFNVKSNSYNNSISIDIELGKDIYLYSNKIKLYINEKDISSLINLPQSSTRGNENVY
YRKLNLALPNLLLERFAKNNTNLIKLEFQGCSEQGLCYNPQTWYFDLISKKNTFEISKPYKAQKTDKKTKIESEESSIAN
FLTTDNFFWILLSFFGYGLLLSLTPCILPMIPILSSLIIAKSNAKFSKKYSFFLSFIYVFFMSLAYAIAGVIASFLGTSI
QGILQKPIILILFALIFIAFAFAMFGAFRFELPLRFQTFIHKKSEKGKGVVGIAIMGFLSALIVGPCVAAPLAGALIYIA
NTGNALLGGSALFIMSFGMGIPLLFIGLGLGFIKPGFWMEKVKIFFSFVMLAMAIWILSRIIEENYILIAYGILGVFFSV
FMGIFEKSFAIISKIKKSILILILAYSLSIFLGGLFGAKNFLNPLNFNTISTSKPALSYDYINNFEQLKQEIQTSIKPIM
LDFTASWCENCKLLDELTFSDERIIQKMQNYKLIKVDVSQNNNEQIKTMKEFNVFGPPVLILFENGKEKLKITGFISADD
LLKKLEP
>Mature_567_residues
MRIFGIILLSICLCFASILSLNEAFNVKSNSYNNSISIDIELGKDIYLYSNKIKLYINEKDISSLINLPQSSTRGNENVY
YRKLNLALPNLLLERFAKNNTNLIKLEFQGCSEQGLCYNPQTWYFDLISKKNTFEISKPYKAQKTDKKTKIESEESSIAN
FLTTDNFFWILLSFFGYGLLLSLTPCILPMIPILSSLIIAKSNAKFSKKYSFFLSFIYVFFMSLAYAIAGVIASFLGTSI
QGILQKPIILILFALIFIAFAFAMFGAFRFELPLRFQTFIHKKSEKGKGVVGIAIMGFLSALIVGPCVAAPLAGALIYIA
NTGNALLGGSALFIMSFGMGIPLLFIGLGLGFIKPGFWMEKVKIFFSFVMLAMAIWILSRIIEENYILIAYGILGVFFSV
FMGIFEKSFAIISKIKKSILILILAYSLSIFLGGLFGAKNFLNPLNFNTISTSKPALSYDYINNFEQLKQEIQTSIKPIM
LDFTASWCENCKLLDELTFSDERIIQKMQNYKLIKVDVSQNNNEQIKTMKEFNVFGPPVLILFENGKEKLKITGFISADD
LLKKLEP

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=594, Percent_Identity=28.2828282828283, Blast_Score=252, Evalue=5e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 63837; Mature: 63837

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFGIILLSICLCFASILSLNEAFNVKSNSYNNSISIDIELGKDIYLYSNKIKLYINEK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEEEEECEEEEEECHH
DISSLINLPQSSTRGNENVYYRKLNLALPNLLLERFAKNNTNLIKLEFQGCSEQGLCYNP
HHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEECC
QTWYFDLISKKNTFEISKPYKAQKTDKKTKIESEESSIANFLTTDNFFWILLSFFGYGLL
CCCEEEECCCCCCEECCCCCCCCCCCCHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LSLTPCILPMIPILSSLIIAKSNAKFSKKYSFFLSFIYVFFMSLAYAIAGVIASFLGTSI
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGILQKPIILILFALIFIAFAFAMFGAFRFELPLRFQTFIHKKSEKGKGVVGIAIMGFLS
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHCCCCCCCEEHHHHHHHHH
ALIVGPCVAAPLAGALIYIANTGNALLGGSALFIMSFGMGIPLLFIGLGLGFIKPGFWME
HHHHHHHHHHHHCCEEEEEEECCCEEECCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHH
KVKIFFSFVMLAMAIWILSRIIEENYILIAYGILGVFFSVFMGIFEKSFAIISKIKKSIL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILILAYSLSIFLGGLFGAKNFLNPLNFNTISTSKPALSYDYINNFEQLKQEIQTSIKPIM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEE
LDFTASWCENCKLLDELTFSDERIIQKMQNYKLIKVDVSQNNNEQIKTMKEFNVFGPPVL
EEEHHHHHHCCHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCCCEE
ILFENGKEKLKITGFISADDLLKKLEP
EEEECCCCEEEEEEEECHHHHHHHCCC
>Mature Secondary Structure
MRIFGIILLSICLCFASILSLNEAFNVKSNSYNNSISIDIELGKDIYLYSNKIKLYINEK
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCEEEEEECEEEEEECHH
DISSLINLPQSSTRGNENVYYRKLNLALPNLLLERFAKNNTNLIKLEFQGCSEQGLCYNP
HHHHHHCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEECC
QTWYFDLISKKNTFEISKPYKAQKTDKKTKIESEESSIANFLTTDNFFWILLSFFGYGLL
CCCEEEECCCCCCEECCCCCCCCCCCCHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHH
LSLTPCILPMIPILSSLIIAKSNAKFSKKYSFFLSFIYVFFMSLAYAIAGVIASFLGTSI
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QGILQKPIILILFALIFIAFAFAMFGAFRFELPLRFQTFIHKKSEKGKGVVGIAIMGFLS
HHHHHCHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHCCCCCCCEEHHHHHHHHH
ALIVGPCVAAPLAGALIYIANTGNALLGGSALFIMSFGMGIPLLFIGLGLGFIKPGFWME
HHHHHHHHHHHHCCEEEEEEECCCEEECCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHH
KVKIFFSFVMLAMAIWILSRIIEENYILIAYGILGVFFSVFMGIFEKSFAIISKIKKSIL
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILILAYSLSIFLGGLFGAKNFLNPLNFNTISTSKPALSYDYINNFEQLKQEIQTSIKPIM
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCEE
LDFTASWCENCKLLDELTFSDERIIQKMQNYKLIKVDVSQNNNEQIKTMKEFNVFGPPVL
EEEHHHHHHCCHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCCCEE
ILFENGKEKLKITGFISADDLLKKLEP
EEEECCCCEEEEEEEECHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]