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The map label for this gene is yhfN [H]

Identifier: 153951342

GI number: 153951342

Start: 1130957

End: 1132144

Strand: Direct

Name: yhfN [H]

Synonym: JJD26997_1283

Alternate gene names: 153951342

Gene position: 1130957-1132144 (Clockwise)

Preceding gene: 153951811

Following gene: 153951215

Centisome position: 61.29

GC content: 28.37

Gene sequence:

>1188_bases
ATGACTTTAATTGCAATTTTATGTCTTTACACAGCACTTTTATCTTGGATTTCCTATGCTCAAATTCGTTTCTTGGAAAG
AGAAAAAGACAAACAAGCTCAAATTTTAAGCGAAAAAGACTATCAAAATGCAGCAGATATTGCCATAGAAAATGAAAAAT
TTAAACTATTTTCCAATTTTTATAATTTAATCATCAATATTGCATGGATAAGTTTTGGATTTTTATATCTTAAAGAATTG
CTTATCTCAAACAACACTCGTTTTGAAAATACTTTATTTTTATTATCTTTTTTAATCATCACAAGTATTTTAAATCTACC
TTTAAGTATTTATGAAAGTTTTATCAAAGATAAAGCCCATGGTTTTTCAAATATGACTGTAAAACTTTTTATCAAAGACA
CTGTAAAAAGTCTTATTTTAACTTTAATATTTGGATTTTTAATCCTTTATGCTTTGCTTTTTTGCTATGATTTTTTTGGA
ACTTTTTGGTGGATTGTGGCCTTTATTTTTGCCTTTTGTATTATAGTGATTACAAATCTCATCTACCCTACTTTGATAGC
ACCTATTTTTAATAAAATGGAAAAACTAAACGATGAAAATTTGCTGAAAAAAATCAGCTCTTTGATGAAACAATGCGGGT
TTAGTGCAAATGGGGTTTATGTTATTGATGCAAGCAAAAGAGATAAGCGTTTAAATGCTTATTTTGGTGGACTTTTTAAA
AGCAAAAGAGTGGTGCTTTTTGATACATTATTAAAAGCCTTAAATGAAAGAGAACTTTTAGCTGTTTTAGGACACGAGCT
TGGACATTTTGTTCATAAGGATATTATCAAAGCTTTATTTAACGGTGCTATAACCATGTTTTTACTTTTTTTTGTTTTTG
CAAATTTACCTGAATTTGTTTACTTAGAAAGTCATCTAGAAGGAGTAAATGGCGGTGTGTTTGCTCTTTTATTCATCTTG
GCAAATATTTTTAGCTTTTTAATCTCTCCTATACTTAATGCCTTAAGTAGAAAAAATGAATTTGTGGCTGATCAACACGG
AGCTAAAGTTACAAGCAAAGAAGATATGAAAAATGCATTGATAGCTCTAGCAAGAGAAAATAAAGCTTTTATCAAAGCAA
GTAAAATATATACATTTTTTTATCTCAGTCATCCAAGTATTAGCGATAGAATCAAGGCTCTTTCTTGA

Upstream 100 bases:

>100_bases
CCAACTTAGTTGAAAAGAATATTATTTTAGATTTTAAACTATTAACTTTATTTCATTATTTTAAGCTAGAATTCGCAAAA
AACCATTCAAGGAAAAATCA

Downstream 100 bases:

>100_bases
CTATAAAAAATGCTCTTATAGAAACTAAATCTAACTTAAAAGGTTATGAAAATGAAGCAGTATTTATACTTTGTGAATAT
CTAAAAAAAGATAAAGCTTG

Product: M48 family peptidase

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTLIAILCLYTALLSWISYAQIRFLEREKDKQAQILSEKDYQNAADIAIENEKFKLFSNFYNLIINIAWISFGFLYLKEL
LISNNTRFENTLFLLSFLIITSILNLPLSIYESFIKDKAHGFSNMTVKLFIKDTVKSLILTLIFGFLILYALLFCYDFFG
TFWWIVAFIFAFCIIVITNLIYPTLIAPIFNKMEKLNDENLLKKISSLMKQCGFSANGVYVIDASKRDKRLNAYFGGLFK
SKRVVLFDTLLKALNERELLAVLGHELGHFVHKDIIKALFNGAITMFLLFFVFANLPEFVYLESHLEGVNGGVFALLFIL
ANIFSFLISPILNALSRKNEFVADQHGAKVTSKEDMKNALIALARENKAFIKASKIYTFFYLSHPSISDRIKALS

Sequences:

>Translated_395_residues
MTLIAILCLYTALLSWISYAQIRFLEREKDKQAQILSEKDYQNAADIAIENEKFKLFSNFYNLIINIAWISFGFLYLKEL
LISNNTRFENTLFLLSFLIITSILNLPLSIYESFIKDKAHGFSNMTVKLFIKDTVKSLILTLIFGFLILYALLFCYDFFG
TFWWIVAFIFAFCIIVITNLIYPTLIAPIFNKMEKLNDENLLKKISSLMKQCGFSANGVYVIDASKRDKRLNAYFGGLFK
SKRVVLFDTLLKALNERELLAVLGHELGHFVHKDIIKALFNGAITMFLLFFVFANLPEFVYLESHLEGVNGGVFALLFIL
ANIFSFLISPILNALSRKNEFVADQHGAKVTSKEDMKNALIALARENKAFIKASKIYTFFYLSHPSISDRIKALS
>Mature_394_residues
TLIAILCLYTALLSWISYAQIRFLEREKDKQAQILSEKDYQNAADIAIENEKFKLFSNFYNLIINIAWISFGFLYLKELL
ISNNTRFENTLFLLSFLIITSILNLPLSIYESFIKDKAHGFSNMTVKLFIKDTVKSLILTLIFGFLILYALLFCYDFFGT
FWWIVAFIFAFCIIVITNLIYPTLIAPIFNKMEKLNDENLLKKISSLMKQCGFSANGVYVIDASKRDKRLNAYFGGLFKS
KRVVLFDTLLKALNERELLAVLGHELGHFVHKDIIKALFNGAITMFLLFFVFANLPEFVYLESHLEGVNGGVFALLFILA
NIFSFLISPILNALSRKNEFVADQHGAKVTSKEDMKNALIALARENKAFIKASKIYTFFYLSHPSISDRIKALS

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=458, Percent_Identity=27.292576419214, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17505484, Length=435, Percent_Identity=28.2758620689655, Blast_Score=159, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6322577, Length=435, Percent_Identity=30.3448275862069, Blast_Score=173, Evalue=5e-44,
Organism=Drosophila melanogaster, GI19922414, Length=430, Percent_Identity=27.6744186046512, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24654305, Length=325, Percent_Identity=24, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI78707252, Length=392, Percent_Identity=22.4489795918367, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI78707254, Length=392, Percent_Identity=22.4489795918367, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 45285; Mature: 45154

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLIAILCLYTALLSWISYAQIRFLEREKDKQAQILSEKDYQNAADIAIENEKFKLFSNF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCEEECCHHHHHHHHH
YNLIINIAWISFGFLYLKELLISNNTRFENTLFLLSFLIITSILNLPLSIYESFIKDKAH
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
GFSNMTVKLFIKDTVKSLILTLIFGFLILYALLFCYDFFGTFWWIVAFIFAFCIIVITNL
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYPTLIAPIFNKMEKLNDENLLKKISSLMKQCGFSANGVYVIDASKRDKRLNAYFGGLFK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHH
SKRVVLFDTLLKALNERELLAVLGHELGHFVHKDIIKALFNGAITMFLLFFVFANLPEFV
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YLESHLEGVNGGVFALLFILANIFSFLISPILNALSRKNEFVADQHGAKVTSKEDMKNAL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHH
IALARENKAFIKASKIYTFFYLSHPSISDRIKALS
HHHHHCCHHHHHHHHEEEEEEEECCCHHHHHHCCC
>Mature Secondary Structure 
TLIAILCLYTALLSWISYAQIRFLEREKDKQAQILSEKDYQNAADIAIENEKFKLFSNF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCEEECCHHHHHHHHH
YNLIINIAWISFGFLYLKELLISNNTRFENTLFLLSFLIITSILNLPLSIYESFIKDKAH
HHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHC
GFSNMTVKLFIKDTVKSLILTLIFGFLILYALLFCYDFFGTFWWIVAFIFAFCIIVITNL
CCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IYPTLIAPIFNKMEKLNDENLLKKISSLMKQCGFSANGVYVIDASKRDKRLNAYFGGLFK
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHH
SKRVVLFDTLLKALNERELLAVLGHELGHFVHKDIIKALFNGAITMFLLFFVFANLPEFV
CCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YLESHLEGVNGGVFALLFILANIFSFLISPILNALSRKNEFVADQHGAKVTSKEDMKNAL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHH
IALARENKAFIKASKIYTFFYLSHPSISDRIKALS
HHHHHCCHHHHHHHHEEEEEEEECCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]