Click here to switch to the map view.

The map label for this gene is kdgR [H]

Identifier: 153948128

GI number: 153948128

Start: 1955954

End: 1956745

Strand: Direct

Name: kdgR [H]

Synonym: YpsIP31758_1683

Alternate gene names: 153948128

Gene position: 1955954-1956745 (Clockwise)

Preceding gene: 153948835

Following gene: 153949509

Centisome position: 41.41

GC content: 44.19

Gene sequence:

>792_bases
ATGGCTATTGCAGATCTAGATAAACAGCCCGACTCTGTCTCGTCGGTGCTGAAGGTTTTTGGCATATTACAAGCGTTGGG
TGAAGAACGGGAAATAGGTATTACCGAGCTTTCTCAGCGAGTCATGATGCCTAAGAGTACAGTTTATCGTTTTCTCCAAA
CCATGAAGTCCTTGGGTTATGTGGCACAGGAAGGCGAATCGGAGAAATATTCCCTCACCCTGAAGCTATTTGAATTGGGT
GCGAAAGCGCTGCAAAATGTCGATTTGATTCGCAGTGCTGATATTCAGATGCGTGAATTATCTAATGAAACTCGTGAAAC
TATTCACTTGGGTGCATTGGATGAAGATAGCATTGTGTATATTCATAAAATTGACTCGATGTATAACCTGCGAATGCATT
CCCGCATTGGTCGCCGCAACCCATTACACAGTACTGCCATTGGGAAGGTGCTATTAGCCTGGCGTGATCGTGGTGAAGTA
GAAGAAATTCTGTCTCATATCGAATTTACCCGCAGCACCAAATATACGTTGGATAGCACTGCTGCACTGTTACCGGTTTT
AGATAAGGTACGTGAGCAAGGGTTTGGTGAGGATATTGAAGAACAGGAAGAAGGTTTGCGTTGTATCGCAGTTCCTGTCT
TTGACCGTTTTGGTGTGGTGATTGCCGGATTAAGTATTTCTTTCCCGACACTACGTTTCGCTGAAGACAGAAAGAGTGAT
TACGTTAAATCGTTACATTGCGCAGCCCGCAATATTTCTGAGCAAATGGGTTACCGCGATTATCCTTTCTGA

Upstream 100 bases:

>100_bases
CACAGTCTCGCAACTTCCCTTTATAATAAAACCATTGTTCTATTTTTTCTAAAACATATTGTTTTATGAATCAAAGAAAA
CTGAGTAGGGTAACTAAAAA

Downstream 100 bases:

>100_bases
TAAAAGTGTCGATAAATAGGGTAAGTACTTTATCGTTATTGGATAACTTTAGTTAGCTGTTAATTATCACTATTTATCAC
TATTTATCTCTTTTTATAAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MAIADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMPKSTVYRFLQTMKSLGYVAQEGESEKYSLTLKLFELG
AKALQNVDLIRSADIQMRELSNETRETIHLGALDEDSIVYIHKIDSMYNLRMHSRIGRRNPLHSTAIGKVLLAWRDRGEV
EEILSHIEFTRSTKYTLDSTAALLPVLDKVREQGFGEDIEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFAEDRKSD
YVKSLHCAARNISEQMGYRDYPF

Sequences:

>Translated_263_residues
MAIADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMPKSTVYRFLQTMKSLGYVAQEGESEKYSLTLKLFELG
AKALQNVDLIRSADIQMRELSNETRETIHLGALDEDSIVYIHKIDSMYNLRMHSRIGRRNPLHSTAIGKVLLAWRDRGEV
EEILSHIEFTRSTKYTLDSTAALLPVLDKVREQGFGEDIEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFAEDRKSD
YVKSLHCAARNISEQMGYRDYPF
>Mature_262_residues
AIADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMPKSTVYRFLQTMKSLGYVAQEGESEKYSLTLKLFELGA
KALQNVDLIRSADIQMRELSNETRETIHLGALDEDSIVYIHKIDSMYNLRMHSRIGRRNPLHSTAIGKVLLAWRDRGEVE
EILSHIEFTRSTKYTLDSTAALLPVLDKVREQGFGEDIEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFAEDRKSDY
VKSLHCAARNISEQMGYRDYPF

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=263, Percent_Identity=86.3117870722433, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI1786468, Length=247, Percent_Identity=39.2712550607287, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI1789999, Length=228, Percent_Identity=34.2105263157895, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1790752, Length=226, Percent_Identity=32.3008849557522, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082359, Length=248, Percent_Identity=29.8387096774194, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786715, Length=229, Percent_Identity=30.5676855895196, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI1788581, Length=223, Percent_Identity=30.4932735426009, Blast_Score=103, Evalue=8e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29853; Mature: 29721

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMPKSTVYRFLQTMKSLGY
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
VAQEGESEKYSLTLKLFELGAKALQNVDLIRSADIQMRELSNETRETIHLGALDEDSIVY
HHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEECCCCCCCEEE
IHKIDSMYNLRMHSRIGRRNPLHSTAIGKVLLAWRDRGEVEEILSHIEFTRSTKYTLDST
EEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHH
AALLPVLDKVREQGFGEDIEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFAEDRKSD
HHHHHHHHHHHHCCCCCCHHHHHCCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
YVKSLHCAARNISEQMGYRDYPF
HHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AIADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMPKSTVYRFLQTMKSLGY
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
VAQEGESEKYSLTLKLFELGAKALQNVDLIRSADIQMRELSNETRETIHLGALDEDSIVY
HHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEEECCCCCCCEEE
IHKIDSMYNLRMHSRIGRRNPLHSTAIGKVLLAWRDRGEVEEILSHIEFTRSTKYTLDST
EEECCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHH
AALLPVLDKVREQGFGEDIEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFAEDRKSD
HHHHHHHHHHHHCCCCCCHHHHHCCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
YVKSLHCAARNISEQMGYRDYPF
HHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]