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The map label for this gene is nanE

Identifier: 153947123

GI number: 153947123

Start: 1513374

End: 1514075

Strand: Reverse

Name: nanE

Synonym: YpsIP31758_1294

Alternate gene names: 153947123

Gene position: 1514075-1513374 (Counterclockwise)

Preceding gene: 153946864

Following gene: 153947675

Centisome position: 32.06

GC content: 55.84

Gene sequence:

>702_bases
GTGAGCAATCTAAGCAATCTCCGCCACAAGCTCCAAAATGGCCTTATCGCCTCATGTCAACCGGTTCCCGGCAGTGCCAT
GGATACGCCTGAGATCGTCGCGGCAATGGCCTGTGCCGCACTGGCGGGCGGTGCTGTCGGTCTACGAATTGAAGGCATCA
GCAACATCCGGGCAGTACGTCGGGCTACAGATGCCCCCATTATTGGCATTATTAAACGCGACTTGCCTGACTCCGAGGTC
AGAATTACCCCTTGGCTGGAAGATATCGATGCACTCAGTGCCGCCGGAGCAGATATTATTGCTTTTGATGTTACCTGCCG
TGAGCGCCCAGTCTCCGTGGCCGATTTATATCAGCGAGCGCGGGCAACCGGCTGCCTGACCATGGCCGATGCCTCCAATA
TTGACGACGGCCTGTTGGCTCATCATCTGGGGATTGATTTTATCGGCACCACCCTTTCCGGCTACACTCAAGCCATCGTG
CCAACCGAGCCCGATCTGGCCTTAGTGACACAGTTAGCGCAAGCCGGGTGCAGGGTCATTGCCGAAGGCCGTTACCATTC
ACCGGCCCTGGCGGCGGCGGCAATATCCGCGGGGGCATATGCCGTTACGGTCGGTTCCGCCATTACCCGTATAGAACATA
TTTGCGGTTGGTTTTGCGATGCAATTAAGCAGTGTGAAACAGAAAAACTGACCGAATACTGA

Upstream 100 bases:

>100_bases
TCGTCATACATCGCCCTTCTTATCGTTGCACCCGACGGATAAACGATCTAACATAATGGAGTTAAACTTCATTTATAATT
TCACATCGGAGTTAAAGACC

Downstream 100 bases:

>100_bases
TTATCGTCATTATTGATTATGGCCCACAGGGCCCTCCACTCTCCCAGTTTATAAGGATGCGTATGAAAAAGTTAACCGGC
CTGATCGCAGCTCCGCACAC

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSNLSNLRHKLQNGLIASCQPVPGSAMDTPEIVAAMACAALAGGAVGLRIEGISNIRAVRRATDAPIIGIIKRDLPDSEV
RITPWLEDIDALSAAGADIIAFDVTCRERPVSVADLYQRARATGCLTMADASNIDDGLLAHHLGIDFIGTTLSGYTQAIV
PTEPDLALVTQLAQAGCRVIAEGRYHSPALAAAAISAGAYAVTVGSAITRIEHICGWFCDAIKQCETEKLTEY

Sequences:

>Translated_233_residues
MSNLSNLRHKLQNGLIASCQPVPGSAMDTPEIVAAMACAALAGGAVGLRIEGISNIRAVRRATDAPIIGIIKRDLPDSEV
RITPWLEDIDALSAAGADIIAFDVTCRERPVSVADLYQRARATGCLTMADASNIDDGLLAHHLGIDFIGTTLSGYTQAIV
PTEPDLALVTQLAQAGCRVIAEGRYHSPALAAAAISAGAYAVTVGSAITRIEHICGWFCDAIKQCETEKLTEY
>Mature_232_residues
SNLSNLRHKLQNGLIASCQPVPGSAMDTPEIVAAMACAALAGGAVGLRIEGISNIRAVRRATDAPIIGIIKRDLPDSEVR
ITPWLEDIDALSAAGADIIAFDVTCRERPVSVADLYQRARATGCLTMADASNIDDGLLAHHLGIDFIGTTLSGYTQAIVP
TEPDLALVTQLAQAGCRVIAEGRYHSPALAAAAISAGAYAVTVGSAITRIEHICGWFCDAIKQCETEKLTEY

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential)

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family

Homologues:

Organism=Escherichia coli, GI1789617, Length=226, Percent_Identity=59.7345132743363, Blast_Score=244, Evalue=4e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NANE_YERP3 (A7FG95)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400273.1
- ProteinModelPortal:   A7FG95
- SMR:   A7FG95
- STRING:   A7FG95
- GeneID:   5386988
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1294
- NMPDR:   fig|349747.3.peg.1250
- eggNOG:   COG3010
- HOGENOM:   HBG296941
- OMA:   EHIVSWF
- ProtClustDB:   PRK01130
- BioCyc:   YPSE349747:YPSIP31758_1294-MONOMER
- HAMAP:   MF_01235
- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70

Pfam domain/function: PF04131 NanE; SSF51366 RibP_bind_barrel

EC number: =5.1.3.9

Molecular weight: Translated: 24499; Mature: 24368

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLSNLRHKLQNGLIASCQPVPGSAMDTPEIVAAMACAALAGGAVGLRIEGISNIRAVR
CCCHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHH
RATDAPIIGIIKRDLPDSEVRITPWLEDIDALSAAGADIIAFDVTCRERPVSVADLYQRA
HHCCCCEEEEEECCCCCCCEEEECCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHH
RATGCLTMADASNIDDGLLAHHLGIDFIGTTLSGYTQAIVPTEPDLALVTQLAQAGCRVI
HHCCEEEECCCCCCCHHHHHHHHCHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCEEE
AEGRYHSPALAAAAISAGAYAVTVGSAITRIEHICGWFCDAIKQCETEKLTEY
ECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure 
SNLSNLRHKLQNGLIASCQPVPGSAMDTPEIVAAMACAALAGGAVGLRIEGISNIRAVR
CCHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHH
RATDAPIIGIIKRDLPDSEVRITPWLEDIDALSAAGADIIAFDVTCRERPVSVADLYQRA
HHCCCCEEEEEECCCCCCCEEEECCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHH
RATGCLTMADASNIDDGLLAHHLGIDFIGTTLSGYTQAIVPTEPDLALVTQLAQAGCRVI
HHCCEEEECCCCCCCHHHHHHHHCHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHCCEEE
AEGRYHSPALAAAAISAGAYAVTVGSAITRIEHICGWFCDAIKQCETEKLTEY
ECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA