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The map label for this gene is phoP [H]

Identifier: 153946864

GI number: 153946864

Start: 1524614

End: 1525321

Strand: Reverse

Name: phoP [H]

Synonym: YpsIP31758_1304

Alternate gene names: 153946864

Gene position: 1525321-1524614 (Counterclockwise)

Preceding gene: 153950667

Following gene: 153947123

Centisome position: 32.29

GC content: 51.55

Gene sequence:

>708_bases
ATGAAAATATTAATTGCCGAAGACAATGCCCATATTCGTAATGGCCTTATGGAAGTATTGGCCCATGAAGGGTACCGCCC
CATCGCGGCAGAAAATGGTGTGCAGGCACTGGCGCTATACCGCCAACAACAGCCGGATTTTATCATTCTTGATATCATGA
TGCCGGAGCTTGATGGCTACAAGGTGTGCAGGGAGATCCGCAAACACGACTGGCAAACGCCCATTATCTTTCTGTCCGCG
AAGGATGAGGAGATTGACCGGGTGATCGGGTTAGAGTTGGGTGCTGACGACTACATCAGTAAGCCCTTCGGTATCCATGA
AATGCGCGCCCGAATCAAGACTATTGTCCGCCGTTGTCTACGAAAAGTACCTGAATCCGCCGAAGACGCAGGCTTCCCGT
TTGGCGATCTGATGGTGTTTCCCAATGAGTTGTGTGCGATTCGTGGAGAGACGCGCCTTGAGCTGTCACTGCGCGAGGTT
AATATCCTACGCTATCTGTATCAGCATAAGGGCCGGGTGGTCACCAGAGATATGTTATTTGATGCGGTTTGGGGATATGA
CCATTTGCCACAGAGCCGTACGCTCGACCAGCATATTTCCAAGCTTCGCAAGACCATTGAACTGGATCCGGTTCATCCGG
TATTGATCCGCACAGTGCACGGGGCGGGTTACCGTTATCAAGGCACGGCGCAGAGCCTGGAAAAATAG

Upstream 100 bases:

>100_bases
GCGAAATTTCCGTCACCAGTAATCCGGCGGGTAGCTGTTTTACCCTAAAACTGCCTATGACGATTAAGCAAGATGCGGCC
ACAGACAAGGAGCAGTTCAC

Downstream 100 bases:

>100_bases
AACCAGCGGGATACGTTTATACGTGGATGAAGTTATATGTGGATGAAGTTATATGTGGATGAAGTTATATGTAGATGAAG
TTATATGTGAGCAACTCGTT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKILIAEDNAHIRNGLMEVLAHEGYRPIAAENGVQALALYRQQQPDFIILDIMMPELDGYKVCREIRKHDWQTPIIFLSA
KDEEIDRVIGLELGADDYISKPFGIHEMRARIKTIVRRCLRKVPESAEDAGFPFGDLMVFPNELCAIRGETRLELSLREV
NILRYLYQHKGRVVTRDMLFDAVWGYDHLPQSRTLDQHISKLRKTIELDPVHPVLIRTVHGAGYRYQGTAQSLEK

Sequences:

>Translated_235_residues
MKILIAEDNAHIRNGLMEVLAHEGYRPIAAENGVQALALYRQQQPDFIILDIMMPELDGYKVCREIRKHDWQTPIIFLSA
KDEEIDRVIGLELGADDYISKPFGIHEMRARIKTIVRRCLRKVPESAEDAGFPFGDLMVFPNELCAIRGETRLELSLREV
NILRYLYQHKGRVVTRDMLFDAVWGYDHLPQSRTLDQHISKLRKTIELDPVHPVLIRTVHGAGYRYQGTAQSLEK
>Mature_235_residues
MKILIAEDNAHIRNGLMEVLAHEGYRPIAAENGVQALALYRQQQPDFIILDIMMPELDGYKVCREIRKHDWQTPIIFLSA
KDEEIDRVIGLELGADDYISKPFGIHEMRARIKTIVRRCLRKVPESAEDAGFPFGDLMVFPNELCAIRGETRLELSLREV
NILRYLYQHKGRVVTRDMLFDAVWGYDHLPQSRTLDQHISKLRKTIELDPVHPVLIRTVHGAGYRYQGTAQSLEK

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=37.9912663755458, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=35.2422907488987, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786599, Length=228, Percent_Identity=36.4035087719298, Blast_Score=141, Evalue=3e-35,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=35.7142857142857, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=36.283185840708, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1790860, Length=234, Percent_Identity=34.1880341880342, Blast_Score=129, Evalue=1e-31,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=32.034632034632, Blast_Score=123, Evalue=8e-30,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=39.0350877192982, Blast_Score=123, Evalue=9e-30,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=31.4159292035398, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=31.25, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=31.25, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI1787375, Length=232, Percent_Identity=30.6034482758621, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=28.8793103448276, Blast_Score=100, Evalue=8e-23,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=27.5555555555556, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=38.3333333333333, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787487, Length=119, Percent_Identity=34.453781512605, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790299, Length=114, Percent_Identity=29.8245614035088, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27132; Mature: 27132

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIAEDNAHIRNGLMEVLAHEGYRPIAAENGVQALALYRQQQPDFIILDIMMPELDGY
CEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHH
KVCREIRKHDWQTPIIFLSAKDEEIDRVIGLELGADDYISKPFGIHEMRARIKTIVRRCL
HHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHH
RKVPESAEDAGFPFGDLMVFPNELCAIRGETRLELSLREVNILRYLYQHKGRVVTRDMLF
HHCCCCCHHCCCCCHHHEECCCHHHEECCCCEEEHHHHHHHHHHHHHHHCCCEEHHHHHH
DAVWGYDHLPQSRTLDQHISKLRKTIELDPVHPVLIRTVHGAGYRYQGTAQSLEK
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHEEECCCCEEECCCHHHHCC
>Mature Secondary Structure
MKILIAEDNAHIRNGLMEVLAHEGYRPIAAENGVQALALYRQQQPDFIILDIMMPELDGY
CEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCHH
KVCREIRKHDWQTPIIFLSAKDEEIDRVIGLELGADDYISKPFGIHEMRARIKTIVRRCL
HHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHHH
RKVPESAEDAGFPFGDLMVFPNELCAIRGETRLELSLREVNILRYLYQHKGRVVTRDMLF
HHCCCCCHHCCCCCHHHEECCCHHHEECCCCEEEHHHHHHHHHHHHHHHCCCEEHHHHHH
DAVWGYDHLPQSRTLDQHISKLRKTIELDPVHPVLIRTVHGAGYRYQGTAQSLEK
HHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHEEECCCCEEECCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]