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The map label for this gene is dipZ [H]

Identifier: 153946977

GI number: 153946977

Start: 4149430

End: 4151217

Strand: Direct

Name: dipZ [H]

Synonym: YpsIP31758_3681

Alternate gene names: 153946977

Gene position: 4149430-4151217 (Clockwise)

Preceding gene: 153950931

Following gene: 153948866

Centisome position: 87.85

GC content: 52.07

Gene sequence:

>1788_bases
ATGGCTCAACGCTTCATTACTCTGATCCTGCTGCTGTGCAGCGTATTACTCGCCCCGCACAGCGCCCAGTCCTCACTCTT
TGGTGAGAATACCTCTTTTGGTGCCAAAAACAGTCAGAGCCGGTTTATTCCGGTCGATCAAGCGTTCGCCTTTGATTTCC
ACCAGCAAGGCGATCAGCTGAATCTGAGTTGGCAAATCCATCCCGGTTACTACCTGTATCGCCAGCAAATAAAAATTGTA
CCGCAGCAAGCGGCTCTGGGAGCATTCACCCTGCCGGAAGGCATTACGCATCATGATGAGTTCTATGGTGAAGTCGAGAT
TTTCAAGCAGCAGTTAACCCTGAAAATCCCCATTACTCAGGCGGCTGAACAGGCTAGCGTCAGTGTGACCTATCAGGGCT
GTGCGGAAGCAGGCTTCTGTTATCCACCAGAAACGCGGGTGATCCCACTTGATGTGGTCGTTGCTGCTTCCACGGCTTCA
GGCACTGCTGCCGTCAATTCGTCCGCTACCGTCAATCCACCAGCGACAACACAGCCAGAGGGCGATGCCACACCAGTACC
GTCTACGTTACCCTTCTCTCCCTTGTGGGCGCTGCTAATCGGTATCGGGATTGCGTTTACCCCCTGTGTTTTACCGATGT
ATCCATTGATTTCAGCCGTCATTCTTGGCCGTGAAAAACCACACAGCCAACGGCGAATACTGATATTAGCGGTGGTGTAC
GTACAAGGGATGGCGCTGACCTATACCTTGCTAGGGTTAGTGGTTGCGGCGGCAGGTTTACAATTCCAGGCCGCGCTACA
GCATCCTTATGTGTTGATTGGCTTGTCGGTATTATTCGTGCTGTTGGCATTATCAATGTTCGGCCTGTATTCATTGCAAT
TACCTTCATCGTTACAGACCCGCCTGACACAGTGGAGTAATAGCCAACGTGGCGGCTCACTGGCCGGTGTATTTGCGATG
GGTGCACTGGCGGGTCTGATTTGTTCTCCCTGCACTACCGCACCGCTGAGCGCGATCCTGCTCTATATTGCCCAAAGCGG
TAATATGCTGGCCGGTGGTGGGACCTTGTACCTATATGCGCTTGGGATGGGGATCCCGCTAGTGGTTGTCACCCTGTTCG
GCAACAAGCTCATTCCACGCAGCGGTCCGTGGATGCAATATGTCAAAGAGGCTTTTGGTTTTGTGATCCTGGCGCTGCCC
GTGTTTTTACTGGAAAGGGTGCTGGGGGATGTCTGGGGTTTACGTTTATGGAGCCTGCTGGCCGTCGCGTTCTTTGGCTG
GGCGTTTGTATTGAGCCTGAAAGCGCACGCTGGTTGGGTGCGGGTCTGCCAGTTATTGCTCTTGGCCGCACTGTTGATCG
TGGCTCGCCCCTTGCAAGATTGGGCCTTTAACGGCAACACGCAGCAGAACGCAGTCAAGCATATAAACTTTCAACCAGTG
GCTAATTTACCCCAATTGCAAGCCGTATTAGCGCAGGCGCAGGGTAAACCGGTGATGCTCGATCTGTATGCAGACTGGTG
TGTGGCCTGTAAAGAGTTTGAGAAATACACTTTCAGTGATGATAAGGTCCAGCGCCAGTTAGCCAATACCCTGTTGCTGC
AAGCGGATGTCACCGCCAACAATGCTGAACATGCCACATTATTGAAGAAATTTAACGTGTTAGGTTTACCCACTATTCTG
TTTTTTGATTCTCAGGGCAACGAGATCACTGCCGCACGGGTCACCGGGTTTATGGACGCTGCGCAATTCTTACAGCATTT
ACAAAACACCCCCGCGGTTACAAAATAA

Upstream 100 bases:

>100_bases
ATCAGCAGGCCCTTCTCACTTATATCAAACAACATCACCCCTACCAGACGCCGGAATTACTGGTGCTACCGGTACGGGAC
GGAGATAAAGATTACCTGTC

Downstream 100 bases:

>100_bases
ATAGCTGTCGCCACGGCGAGTAGGTCTCGCCGTGGCATAATCAACGCTCAATCACGACAAGTCATGGTACAACTGCGGCG
TCTGATAACCGTTTTTTCAA

Product: thiol:disulfide interchange protein precursor

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MAQRFITLILLLCSVLLAPHSAQSSLFGENTSFGAKNSQSRFIPVDQAFAFDFHQQGDQLNLSWQIHPGYYLYRQQIKIV
PQQAALGAFTLPEGITHHDEFYGEVEIFKQQLTLKIPITQAAEQASVSVTYQGCAEAGFCYPPETRVIPLDVVVAASTAS
GTAAVNSSATVNPPATTQPEGDATPVPSTLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGREKPHSQRRILILAVVY
VQGMALTYTLLGLVVAAAGLQFQAALQHPYVLIGLSVLFVLLALSMFGLYSLQLPSSLQTRLTQWSNSQRGGSLAGVFAM
GALAGLICSPCTTAPLSAILLYIAQSGNMLAGGGTLYLYALGMGIPLVVVTLFGNKLIPRSGPWMQYVKEAFGFVILALP
VFLLERVLGDVWGLRLWSLLAVAFFGWAFVLSLKAHAGWVRVCQLLLLAALLIVARPLQDWAFNGNTQQNAVKHINFQPV
ANLPQLQAVLAQAQGKPVMLDLYADWCVACKEFEKYTFSDDKVQRQLANTLLLQADVTANNAEHATLLKKFNVLGLPTIL
FFDSQGNEITAARVTGFMDAAQFLQHLQNTPAVTK

Sequences:

>Translated_595_residues
MAQRFITLILLLCSVLLAPHSAQSSLFGENTSFGAKNSQSRFIPVDQAFAFDFHQQGDQLNLSWQIHPGYYLYRQQIKIV
PQQAALGAFTLPEGITHHDEFYGEVEIFKQQLTLKIPITQAAEQASVSVTYQGCAEAGFCYPPETRVIPLDVVVAASTAS
GTAAVNSSATVNPPATTQPEGDATPVPSTLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGREKPHSQRRILILAVVY
VQGMALTYTLLGLVVAAAGLQFQAALQHPYVLIGLSVLFVLLALSMFGLYSLQLPSSLQTRLTQWSNSQRGGSLAGVFAM
GALAGLICSPCTTAPLSAILLYIAQSGNMLAGGGTLYLYALGMGIPLVVVTLFGNKLIPRSGPWMQYVKEAFGFVILALP
VFLLERVLGDVWGLRLWSLLAVAFFGWAFVLSLKAHAGWVRVCQLLLLAALLIVARPLQDWAFNGNTQQNAVKHINFQPV
ANLPQLQAVLAQAQGKPVMLDLYADWCVACKEFEKYTFSDDKVQRQLANTLLLQADVTANNAEHATLLKKFNVLGLPTIL
FFDSQGNEITAARVTGFMDAAQFLQHLQNTPAVTK
>Mature_594_residues
AQRFITLILLLCSVLLAPHSAQSSLFGENTSFGAKNSQSRFIPVDQAFAFDFHQQGDQLNLSWQIHPGYYLYRQQIKIVP
QQAALGAFTLPEGITHHDEFYGEVEIFKQQLTLKIPITQAAEQASVSVTYQGCAEAGFCYPPETRVIPLDVVVAASTASG
TAAVNSSATVNPPATTQPEGDATPVPSTLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGREKPHSQRRILILAVVYV
QGMALTYTLLGLVVAAAGLQFQAALQHPYVLIGLSVLFVLLALSMFGLYSLQLPSSLQTRLTQWSNSQRGGSLAGVFAMG
ALAGLICSPCTTAPLSAILLYIAQSGNMLAGGGTLYLYALGMGIPLVVVTLFGNKLIPRSGPWMQYVKEAFGFVILALPV
FLLERVLGDVWGLRLWSLLAVAFFGWAFVLSLKAHAGWVRVCQLLLLAALLIVARPLQDWAFNGNTQQNAVKHINFQPVA
NLPQLQAVLAQAQGKPVMLDLYADWCVACKEFEKYTFSDDKVQRQLANTLLLQADVTANNAEHATLLKKFNVLGLPTILF
FDSQGNEITAARVTGFMDAAQFLQHLQNTPAVTK

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=589, Percent_Identity=63.8370118845501, Blast_Score=753, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 64507; Mature: 64376

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQRFITLILLLCSVLLAPHSAQSSLFGENTSFGAKNSQSRFIPVDQAFAFDFHQQGDQL
CHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCEE
NLSWQIHPGYYLYRQQIKIVPQQAALGAFTLPEGITHHDEFYGEVEIFKQQLTLKIPITQ
EEEEEECCCCCEEEHHHHCCCHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHEEEECCHH
AAEQASVSVTYQGCAEAGFCYPPETRVIPLDVVVAASTASGTAAVNSSATVNPPATTQPE
HHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEECCCCCCCCCCCCCCC
GDATPVPSTLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGREKPHSQRRILILAVVY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VQGMALTYTLLGLVVAAAGLQFQAALQHPYVLIGLSVLFVLLALSMFGLYSLQLPSSLQT
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RLTQWSNSQRGGSLAGVFAMGALAGLICSPCTTAPLSAILLYIAQSGNMLAGGGTLYLYA
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCEEEEHH
LGMGIPLVVVTLFGNKLIPRSGPWMQYVKEAFGFVILALPVFLLERVLGDVWGLRLWSLL
HHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAFFGWAFVLSLKAHAGWVRVCQLLLLAALLIVARPLQDWAFNGNTQQNAVKHINFQPV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHCCCCCCC
ANLPQLQAVLAQAQGKPVMLDLYADWCVACKEFEKYTFSDDKVQRQLANTLLLQADVTAN
CCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCCCC
NAEHATLLKKFNVLGLPTILFFDSQGNEITAARVTGFMDAAQFLQHLQNTPAVTK
CCHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AQRFITLILLLCSVLLAPHSAQSSLFGENTSFGAKNSQSRFIPVDQAFAFDFHQQGDQL
HHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCCCEEECCHHHHHHHHCCCCEE
NLSWQIHPGYYLYRQQIKIVPQQAALGAFTLPEGITHHDEFYGEVEIFKQQLTLKIPITQ
EEEEEECCCCCEEEHHHHCCCHHHHCCCEECCCCCCCHHHHHHHHHHHHHHHEEEECCHH
AAEQASVSVTYQGCAEAGFCYPPETRVIPLDVVVAASTASGTAAVNSSATVNPPATTQPE
HHCCCEEEEEECCCCCCCCCCCCCCCEEEEEEEEEECCCCCCEEECCCCCCCCCCCCCCC
GDATPVPSTLPFSPLWALLIGIGIAFTPCVLPMYPLISAVILGREKPHSQRRILILAVVY
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
VQGMALTYTLLGLVVAAAGLQFQAALQHPYVLIGLSVLFVLLALSMFGLYSLQLPSSLQT
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
RLTQWSNSQRGGSLAGVFAMGALAGLICSPCTTAPLSAILLYIAQSGNMLAGGGTLYLYA
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCEEEEHH
LGMGIPLVVVTLFGNKLIPRSGPWMQYVKEAFGFVILALPVFLLERVLGDVWGLRLWSLL
HHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAFFGWAFVLSLKAHAGWVRVCQLLLLAALLIVARPLQDWAFNGNTQQNAVKHINFQPV
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHCCCCCCC
ANLPQLQAVLAQAQGKPVMLDLYADWCVACKEFEKYTFSDDKVQRQLANTLLLQADVTAN
CCCHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEECCCCC
NAEHATLLKKFNVLGLPTILFFDSQGNEITAARVTGFMDAAQFLQHLQNTPAVTK
CCHHHHHHHHHCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA