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The map label for this gene is stc [H]

Identifier: 153937365

GI number: 153937365

Start: 1762225

End: 1764189

Strand: Direct

Name: stc [H]

Synonym: CLC_1672

Alternate gene names: 153937365

Gene position: 1762225-1764189 (Clockwise)

Preceding gene: 153936605

Following gene: 153934609

Centisome position: 46.86

GC content: 29.36

Gene sequence:

>1965_bases
GTGAAGGATTACTTAAAGTTTATACATAATGCTTGGGAAAGATTTATTGAAACTGATTATATAGATAATAAAGTAAGGAT
TGAAATAGCAGAATCTTGGAGAAGATGTAAAGATTACAGTGTAGATCACATGAGTGGGCGAGGAAGTAGTAGAAATAAGA
TTTCAGTAGAATTTAAGGGTCAAGAAAATGCCCAGCTAATTTCAGTGGCGAAACCTATAATGAAAGGCATATACAATATT
GTTGAAGGTTCTGATTTTGCCATAATATTATCAGATAAGGATGGATATATAATTGAAGTAATTGGGGATAAAGACATAAT
GAAGAGGGTAGAAGAATTAAATTTTGTAAAGGGTGCCCTTTGGACTGAAAAAGCTGTTGGAACAAATGCCATAGGTACAG
CTCTTTGTTTAGATAAACCTATACAAACTATTGGTGCAGAACATTTTTGTATAAGTCAGCATTCCTGGACTTGTTCAGCC
TGTCCTATTCATGATGAATACGGAAATATAATAGGATGTTTAAATATGTCTGGTAATTCTTATAACGCTCATTCTCATAC
ACTGGGTATCGTAACAGCCTCTGCACAAGCTATAGAAAAACAATTAGCTTTAACTATTTCTTATAATCTTATAAATATAA
CCTTTGATTCTATTTCTGAAGGCATGATTATTCTAGATAAAAATTTTAATATAAAAAGACTAAATCATAGAGCTGAAGAA
ATTTTATTTATAAGTAGTGACTATGCTTTAGGCATAAATATTCACAGTATATTAAAAAATATTAGTTTTAAAGAAATTCT
AAAAGAAAGTCATAAAAGTTACAGTAATATAGAAGGAGATTTTCATATAAATGATAATAGAGTTAAATGTATTGTAAATG
CGGTACCTATAAAGAGTAATAGAAAAATCACAGGTATTGTTATAACTTTTAGGGAAGCTACTTTAGTTCATAAATTAGTT
AATAAAGTAATAGGATATAAGGCTTCTTATAATTTTGACAATATAATAACTGTAAATGAAAAGATGATTGAAATTATTGA
ATTGGCTAAAAAAGCATCTAAGAGTAACTGTAATATACTCATTGAAGGAGAAAGTGGTACAGGAAAAGAACTAATCGCAC
AATCTATACACAATTATAGTATGAGAGCAACAGGTCCCTTTTTAGCTGTAAATTGTGCATCTATACCTAGAGAACTTGTT
GAAAGCGAACTTTTTGGATATGAAAGAGGAGCCTTTACAGGAGCTTCAAAGGAAGGCCATCCAGGGAAATTTGAGTTAGC
AGATGGAGGTACAATATTTTTAGATGAGCTGGGAGAATTGCCTTTAGACATGCAATCTAAATTATTAAGAGTGTTAGATA
ATAATAAAATTATAAGAGTGGGAGGAACCTATGAAAAGCAGCTAAATGTGAGAGTTATAGGAGCAACTAATAGAAATTTA
AAGGAAGAAATGAAAAAGAAAAATTTCAGAGAAGATCTTTATTATAGGTTAGGTGTAATAAATATAAAAATCCTACCATT
AAGGTACAGAAAAGAGGATATAGAAGTTTTGGTTAATAGTTTCGTCATGAATCTTAACCAAAGAAATTTACAAGAAAATA
AAAGAGTAAAAAAAGCATATATAGATAAATTAAAGGATTATGATTGGCCAGGTAATGTAAGAGAGCTTAGAAATGTGGTA
GAAAGAGATTATTATTTAAGCGATACAGGCACAGTTTCACCTTACTATATTGAAAAAAATATATTTTTAGAAACCAATAA
TGAAAATTATGAAAATAAAGATATAAATATTATTCCTATGGAAAAGTTGGAAAAGGAAAATATTGAAAATGCTATAGAAA
AATGTGATGGAAACTTGGCTAAAGCAGCAAGACTATTGGATATTGGCCGATCTACATTGTACAGAAAAATAAAAAAATAT
AATATAAAAGAAAGATATAGAATTACGTACACGGAAAAGGAGTAA

Upstream 100 bases:

>100_bases
AAATCTCGCTAAATTTATATACATATTTGTAAAATTAGGTTTGTTCCATGAATAATTAAGTATTTATTTAATATTTAAAA
TTATTTTTCGAGGTGAGAGT

Downstream 100 bases:

>100_bases
AATATCATGCGTAAATTATCACAAGAGGAATTTAAAGAGATATTAAAGAATAGGAACCCAAAAGAAAGGCTTGTTTTAAA
AGAGATAGAACTTTTTGATA

Product: sensory box sigma-54 dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MKDYLKFIHNAWERFIETDYIDNKVRIEIAESWRRCKDYSVDHMSGRGSSRNKISVEFKGQENAQLISVAKPIMKGIYNI
VEGSDFAIILSDKDGYIIEVIGDKDIMKRVEELNFVKGALWTEKAVGTNAIGTALCLDKPIQTIGAEHFCISQHSWTCSA
CPIHDEYGNIIGCLNMSGNSYNAHSHTLGIVTASAQAIEKQLALTISYNLINITFDSISEGMIILDKNFNIKRLNHRAEE
ILFISSDYALGINIHSILKNISFKEILKESHKSYSNIEGDFHINDNRVKCIVNAVPIKSNRKITGIVITFREATLVHKLV
NKVIGYKASYNFDNIITVNEKMIEIIELAKKASKSNCNILIEGESGTGKELIAQSIHNYSMRATGPFLAVNCASIPRELV
ESELFGYERGAFTGASKEGHPGKFELADGGTIFLDELGELPLDMQSKLLRVLDNNKIIRVGGTYEKQLNVRVIGATNRNL
KEEMKKKNFREDLYYRLGVINIKILPLRYRKEDIEVLVNSFVMNLNQRNLQENKRVKKAYIDKLKDYDWPGNVRELRNVV
ERDYYLSDTGTVSPYYIEKNIFLETNNENYENKDINIIPMEKLEKENIENAIEKCDGNLAKAARLLDIGRSTLYRKIKKY
NIKERYRITYTEKE

Sequences:

>Translated_654_residues
MKDYLKFIHNAWERFIETDYIDNKVRIEIAESWRRCKDYSVDHMSGRGSSRNKISVEFKGQENAQLISVAKPIMKGIYNI
VEGSDFAIILSDKDGYIIEVIGDKDIMKRVEELNFVKGALWTEKAVGTNAIGTALCLDKPIQTIGAEHFCISQHSWTCSA
CPIHDEYGNIIGCLNMSGNSYNAHSHTLGIVTASAQAIEKQLALTISYNLINITFDSISEGMIILDKNFNIKRLNHRAEE
ILFISSDYALGINIHSILKNISFKEILKESHKSYSNIEGDFHINDNRVKCIVNAVPIKSNRKITGIVITFREATLVHKLV
NKVIGYKASYNFDNIITVNEKMIEIIELAKKASKSNCNILIEGESGTGKELIAQSIHNYSMRATGPFLAVNCASIPRELV
ESELFGYERGAFTGASKEGHPGKFELADGGTIFLDELGELPLDMQSKLLRVLDNNKIIRVGGTYEKQLNVRVIGATNRNL
KEEMKKKNFREDLYYRLGVINIKILPLRYRKEDIEVLVNSFVMNLNQRNLQENKRVKKAYIDKLKDYDWPGNVRELRNVV
ERDYYLSDTGTVSPYYIEKNIFLETNNENYENKDINIIPMEKLEKENIENAIEKCDGNLAKAARLLDIGRSTLYRKIKKY
NIKERYRITYTEKE
>Mature_654_residues
MKDYLKFIHNAWERFIETDYIDNKVRIEIAESWRRCKDYSVDHMSGRGSSRNKISVEFKGQENAQLISVAKPIMKGIYNI
VEGSDFAIILSDKDGYIIEVIGDKDIMKRVEELNFVKGALWTEKAVGTNAIGTALCLDKPIQTIGAEHFCISQHSWTCSA
CPIHDEYGNIIGCLNMSGNSYNAHSHTLGIVTASAQAIEKQLALTISYNLINITFDSISEGMIILDKNFNIKRLNHRAEE
ILFISSDYALGINIHSILKNISFKEILKESHKSYSNIEGDFHINDNRVKCIVNAVPIKSNRKITGIVITFREATLVHKLV
NKVIGYKASYNFDNIITVNEKMIEIIELAKKASKSNCNILIEGESGTGKELIAQSIHNYSMRATGPFLAVNCASIPRELV
ESELFGYERGAFTGASKEGHPGKFELADGGTIFLDELGELPLDMQSKLLRVLDNNKIIRVGGTYEKQLNVRVIGATNRNL
KEEMKKKNFREDLYYRLGVINIKILPLRYRKEDIEVLVNSFVMNLNQRNLQENKRVKKAYIDKLKDYDWPGNVRELRNVV
ERDYYLSDTGTVSPYYIEKNIFLETNNENYENKDINIIPMEKLEKENIENAIEKCDGNLAKAARLLDIGRSTLYRKIKKY
NIKERYRITYTEKE

Specific function: Member Of The Two-Component Regulatory System Atos/Atoc Involved In The Transcriptional Regulation Of The Ato Genes For Acetoacetate Metabolism. Also An Inhibitor Of Polyamine Biosynthesis. [C]

COG id: COG3284

COG function: function code QK; Transcriptional activator of acetoin/glycerol metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=327, Percent_Identity=38.5321100917431, Blast_Score=242, Evalue=6e-65,
Organism=Escherichia coli, GI1789233, Length=444, Percent_Identity=32.6576576576577, Blast_Score=238, Evalue=8e-64,
Organism=Escherichia coli, GI87082117, Length=344, Percent_Identity=37.5, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI87081858, Length=630, Percent_Identity=25.7142857142857, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1790437, Length=290, Percent_Identity=43.448275862069, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1786524, Length=327, Percent_Identity=38.5321100917431, Blast_Score=228, Evalue=7e-61,
Organism=Escherichia coli, GI1790299, Length=333, Percent_Identity=38.1381381381381, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1788905, Length=320, Percent_Identity=37.5, Blast_Score=228, Evalue=1e-60,
Organism=Escherichia coli, GI1789087, Length=315, Percent_Identity=39.3650793650794, Blast_Score=217, Evalue=2e-57,
Organism=Escherichia coli, GI87082152, Length=318, Percent_Identity=37.1069182389937, Blast_Score=208, Evalue=8e-55,
Organism=Escherichia coli, GI87081872, Length=321, Percent_Identity=37.0716510903427, Blast_Score=202, Evalue=7e-53,
Organism=Escherichia coli, GI1787583, Length=260, Percent_Identity=40.7692307692308, Blast_Score=195, Evalue=8e-51,
Organism=Escherichia coli, GI1789828, Length=316, Percent_Identity=31.9620253164557, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR002078 [H]

Pfam domain/function: PF02954 HTH_8; PF00989 PAS; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 74688; Mature: 74688

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDYLKFIHNAWERFIETDYIDNKVRIEIAESWRRCKDYSVDHMSGRGSSRNKISVEFKG
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
QENAQLISVAKPIMKGIYNIVEGSDFAIILSDKDGYIIEVIGDKDIMKRVEELNFVKGAL
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHH
WTEKAVGTNAIGTALCLDKPIQTIGAEHFCISQHSWTCSACPIHDEYGNIIGCLNMSGNS
HHHHCCCCCCHHHHHHHCCCHHHCCCCEEEECCCCCEEECCCCCCCCCCEEEEEEECCCC
YNAHSHTLGIVTASAQAIEKQLALTISYNLINITFDSISEGMIILDKNFNIKRLNHRAEE
CCCCCEEEEEEECCHHHHHHHEEEEEEEEEEEEEECCCCCCEEEEECCCCHHHHCCCCEE
ILFISSDYALGINIHSILKNISFKEILKESHKSYSNIEGDFHINDNRVKCIVNAVPIKSN
EEEEECCCEEEEEHHHHHHCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEEEEEECCCCC
RKITGIVITFREATLVHKLVNKVIGYKASYNFDNIITVNEKMIEIIELAKKASKSNCNIL
CEEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCEEE
IEGESGTGKELIAQSIHNYSMRATGPFLAVNCASIPRELVESELFGYERGAFTGASKEGH
EECCCCCCHHHHHHHHHCCCEECCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PGKFELADGGTIFLDELGELPLDMQSKLLRVLDNNKIIRVGGTYEKQLNVRVIGATNRNL
CCEEEECCCCEEEEEHHCCCCCCHHHHHHHHHCCCCEEEECCCEEEEEEEEEEECCCCCH
KEEMKKKNFREDLYYRLGVINIKILPLRYRKEDIEVLVNSFVMNLNQRNLQENKRVKKAY
HHHHHHCCHHHHHHHEEEEEEEEEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IDKLKDYDWPGNVRELRNVVERDYYLSDTGTVSPYYIEKNIFLETNNENYENKDINIIPM
HHHHHCCCCCCCHHHHHHHHHCCEEECCCCCCCCEEEEEEEEEEECCCCCCCCCEEEEEH
EKLEKENIENAIEKCDGNLAKAARLLDIGRSTLYRKIKKYNIKERYRITYTEKE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC
>Mature Secondary Structure
MKDYLKFIHNAWERFIETDYIDNKVRIEIAESWRRCKDYSVDHMSGRGSSRNKISVEFKG
CHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCCCCEEEEEECC
QENAQLISVAKPIMKGIYNIVEGSDFAIILSDKDGYIIEVIGDKDIMKRVEELNFVKGAL
CCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHH
WTEKAVGTNAIGTALCLDKPIQTIGAEHFCISQHSWTCSACPIHDEYGNIIGCLNMSGNS
HHHHCCCCCCHHHHHHHCCCHHHCCCCEEEECCCCCEEECCCCCCCCCCEEEEEEECCCC
YNAHSHTLGIVTASAQAIEKQLALTISYNLINITFDSISEGMIILDKNFNIKRLNHRAEE
CCCCCEEEEEEECCHHHHHHHEEEEEEEEEEEEEECCCCCCEEEEECCCCHHHHCCCCEE
ILFISSDYALGINIHSILKNISFKEILKESHKSYSNIEGDFHINDNRVKCIVNAVPIKSN
EEEEECCCEEEEEHHHHHHCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEEEEEECCCCC
RKITGIVITFREATLVHKLVNKVIGYKASYNFDNIITVNEKMIEIIELAKKASKSNCNIL
CEEEEEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCEEE
IEGESGTGKELIAQSIHNYSMRATGPFLAVNCASIPRELVESELFGYERGAFTGASKEGH
EECCCCCCHHHHHHHHHCCCEECCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
PGKFELADGGTIFLDELGELPLDMQSKLLRVLDNNKIIRVGGTYEKQLNVRVIGATNRNL
CCEEEECCCCEEEEEHHCCCCCCHHHHHHHHHCCCCEEEECCCEEEEEEEEEEECCCCCH
KEEMKKKNFREDLYYRLGVINIKILPLRYRKEDIEVLVNSFVMNLNQRNLQENKRVKKAY
HHHHHHCCHHHHHHHEEEEEEEEEEEEEECHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
IDKLKDYDWPGNVRELRNVVERDYYLSDTGTVSPYYIEKNIFLETNNENYENKDINIIPM
HHHHHCCCCCCCHHHHHHHHHCCEEECCCCCCCCEEEEEEEEEEECCCCCCCCCEEEEEH
EKLEKENIENAIEKCDGNLAKAARLLDIGRSTLYRKIKKYNIKERYRITYTEKE
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA