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The map label for this gene is lytT [H]

Identifier: 153936493

GI number: 153936493

Start: 1130093

End: 1130800

Strand: Reverse

Name: lytT [H]

Synonym: CLC_1105

Alternate gene names: 153936493

Gene position: 1130800-1130093 (Counterclockwise)

Preceding gene: 153935095

Following gene: 153934688

Centisome position: 30.07

GC content: 23.59

Gene sequence:

>708_bases
ATGCTAAAGTTAGCTATTTGTGATGATGAAAAAACCCAAAGAGAAGAAATAGTAGGTATTATTGTTGAAGCTTTACGATT
AAAAAACAAACAGTATAAAATATCTGAATTTAATAATGGAGAAGATTTAATATCCTCAACAGATGACTTTGATATATATT
TTTTAGATATAAAAATGGATAAATTAACGGGCCTAGAAGTTGCAAAAAAAATTAGACTTATAAATGAAGAAGCAGTTATT
GTATTTATAACAGGACTTAAAGATTATGTTTTTGACGCATTTGACGTAAAGGCTTTTCACTATATTTTAAAACCCATTGA
TGAAAGTAAACTTAAAGATGTTTTATGTTCAGCTTTACTGCAGTTTGATAAAAAAGATAAGTTTATTATTGCTAAAACAA
TTAGCCAAGCTACTAAAATTTTTCTTAAAGATATAATGTACATAGAATCACAACATAGGAAACTAAAAATCCATACTAAA
AATAATATTATTGAATATTACCATAAAATATCTGATATTGAAAAAGAACTTTATGGATGTAATTTTTTTAGATGTCATAA
AAGTTATATTGTAAATTTAAAGTATGTTGAAAGCTATGATAATGTATTTATAACCTTAATAAACTCAGAAAAAATATATG
TTTCAAAATATAGATTAGATGATTTTTCAAAGGCCTTTATGTATTATTTAAAAAATGAGGTTCAGTAA

Upstream 100 bases:

>100_bases
TATAATCGCTTAAAACTCATTTTATTACCATCTAGTTTTAGCCTATAAAATTTTATTTATAGACTTAGTTAGATGGTATA
CTTACTTTGGAGGTGATTCA

Downstream 100 bases:

>100_bases
TTATGGAAAAACAACAAATATTACAGATTTCTCGATTTTTATCAGGATACTCAACAATGATTTTTCTATATACAATCAAA
TACTATTTCTATAAAAATTT

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MLKLAICDDEKTQREEIVGIIVEALRLKNKQYKISEFNNGEDLISSTDDFDIYFLDIKMDKLTGLEVAKKIRLINEEAVI
VFITGLKDYVFDAFDVKAFHYILKPIDESKLKDVLCSALLQFDKKDKFIIAKTISQATKIFLKDIMYIESQHRKLKIHTK
NNIIEYYHKISDIEKELYGCNFFRCHKSYIVNLKYVESYDNVFITLINSEKIYVSKYRLDDFSKAFMYYLKNEVQ

Sequences:

>Translated_235_residues
MLKLAICDDEKTQREEIVGIIVEALRLKNKQYKISEFNNGEDLISSTDDFDIYFLDIKMDKLTGLEVAKKIRLINEEAVI
VFITGLKDYVFDAFDVKAFHYILKPIDESKLKDVLCSALLQFDKKDKFIIAKTISQATKIFLKDIMYIESQHRKLKIHTK
NNIIEYYHKISDIEKELYGCNFFRCHKSYIVNLKYVESYDNVFITLINSEKIYVSKYRLDDFSKAFMYYLKNEVQ
>Mature_235_residues
MLKLAICDDEKTQREEIVGIIVEALRLKNKQYKISEFNNGEDLISSTDDFDIYFLDIKMDKLTGLEVAKKIRLINEEAVI
VFITGLKDYVFDAFDVKAFHYILKPIDESKLKDVLCSALLQFDKKDKFIIAKTISQATKIFLKDIMYIESQHRKLKIHTK
NNIIEYYHKISDIEKELYGCNFFRCHKSYIVNLKYVESYDNVFITLINSEKIYVSKYRLDDFSKAFMYYLKNEVQ

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=217, Percent_Identity=27.1889400921659, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI87082052, Length=247, Percent_Identity=27.5303643724696, Blast_Score=78, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 27822; Mature: 27822

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLAICDDEKTQREEIVGIIVEALRLKNKQYKISEFNNGEDLISSTDDFDIYFLDIKMD
CEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHCCCCCCEEEEEEEEEC
KLTGLEVAKKIRLINEEAVIVFITGLKDYVFDAFDVKAFHYILKPIDESKLKDVLCSALL
HHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QFDKKDKFIIAKTISQATKIFLKDIMYIESQHRKLKIHTKNNIIEYYHKISDIEKELYGC
HCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCC
NFFRCHKSYIVNLKYVESYDNVFITLINSEKIYVSKYRLDDFSKAFMYYLKNEVQ
CCEEECHHHEEEEEEEECCCCEEEEEEECCEEEEEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKLAICDDEKTQREEIVGIIVEALRLKNKQYKISEFNNGEDLISSTDDFDIYFLDIKMD
CEEEEEECCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHCCCCCCEEEEEEEEEC
KLTGLEVAKKIRLINEEAVIVFITGLKDYVFDAFDVKAFHYILKPIDESKLKDVLCSALL
HHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
QFDKKDKFIIAKTISQATKIFLKDIMYIESQHRKLKIHTKNNIIEYYHKISDIEKELYGC
HCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHCC
NFFRCHKSYIVNLKYVESYDNVFITLINSEKIYVSKYRLDDFSKAFMYYLKNEVQ
CCEEECHHHEEEEEEEECCCCEEEEEEECCEEEEEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]