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The map label for this gene is clpP [H]

Identifier: 153932099

GI number: 153932099

Start: 2573969

End: 2574727

Strand: Reverse

Name: clpP [H]

Synonym: CLB_2447

Alternate gene names: 153932099

Gene position: 2574727-2573969 (Counterclockwise)

Preceding gene: 153932756

Following gene: 153931359

Centisome position: 66.64

GC content: 30.04

Gene sequence:

>759_bases
ATGGCAAATAAGAAATTTTGGGAGGTTAAAAACTCAACAGAAAATGAAAACATAGGAGAAGCGTATATCTATGGTGATAT
AGTGTCTTATAAATGGGATGATACTGATACAACTGCAAAAAGTTTTAAAGAAGACTTAGATAGTTTAGGAGACATTGATA
CTTTAAATATATATATTAATTCTCCTGGTGGATCAGTATTTCAAGGGCAAGCAATCTACAACATAATTAAAAGACATAAA
GCAAAAATAAATATTCACGTTGATGGAGTTGCAGCAAGTATCGCAAGTGTTATAGCAATGGCAGGCAATACTATTTTTAT
GCCTAAAAATAGCATGATGATGATTCATAATCCTTGGACATTTGCTTATGGGAATGCAAAAGAACTAAGAAAACAAGCAG
ATGATTTAGATAAAATAAGAGAAAGCTTAATTGAAGCTTACTTAAGTAAAGCAGGCGATAAACTTAGTAGAGAAACACTA
ATAGGAATTATGGATAATGAGACATGGCTTACAGCTCAGGAATGTTATGATTATGGATTATGTGATGAATTAGTAGAAGA
AAAAGAAATAGCAGCAAGCATTAATACAGAGCTATTCGCTAAGTATAAAAATACTCCTAAGGAGTTATTAAATAAAACTG
AAAAACAAAATAAACCTATAAAAAATACTGAAAAAATAGAAAAGGATGAAGAGATAGAGGCTCTTATAGCAAGGGTAAAT
AATATTTTAAAATTTGAGGAGGAAAGAATATATGAATAG

Upstream 100 bases:

>100_bases
GAAGAAATGCAACCGATAAAAGGTGGAGATCAATTATTTGTATCAAGGGATTTGATTCCGATAGATAAAATTGATTTATT
ACTGAAAGGGGGTGAAAAGA

Downstream 100 bases:

>100_bases
ATATCAATTAGAACAAATGTTAGCAGGAATAGGTCAGGATTTAAAAGCAGCAAATGAAAAATTAACCTCTATGTATGCTG
ATGCAAAGACTACATTAGAA

Product: putative Clp protease

Products: NA

Alternate protein names: Endopeptidase Clp [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MANKKFWEVKNSTENENIGEAYIYGDIVSYKWDDTDTTAKSFKEDLDSLGDIDTLNIYINSPGGSVFQGQAIYNIIKRHK
AKINIHVDGVAASIASVIAMAGNTIFMPKNSMMMIHNPWTFAYGNAKELRKQADDLDKIRESLIEAYLSKAGDKLSRETL
IGIMDNETWLTAQECYDYGLCDELVEEKEIAASINTELFAKYKNTPKELLNKTEKQNKPIKNTEKIEKDEEIEALIARVN
NILKFEEERIYE

Sequences:

>Translated_252_residues
MANKKFWEVKNSTENENIGEAYIYGDIVSYKWDDTDTTAKSFKEDLDSLGDIDTLNIYINSPGGSVFQGQAIYNIIKRHK
AKINIHVDGVAASIASVIAMAGNTIFMPKNSMMMIHNPWTFAYGNAKELRKQADDLDKIRESLIEAYLSKAGDKLSRETL
IGIMDNETWLTAQECYDYGLCDELVEEKEIAASINTELFAKYKNTPKELLNKTEKQNKPIKNTEKIEKDEEIEALIARVN
NILKFEEERIYE
>Mature_251_residues
ANKKFWEVKNSTENENIGEAYIYGDIVSYKWDDTDTTAKSFKEDLDSLGDIDTLNIYINSPGGSVFQGQAIYNIIKRHKA
KINIHVDGVAASIASVIAMAGNTIFMPKNSMMMIHNPWTFAYGNAKELRKQADDLDKIRESLIEAYLSKAGDKLSRETLI
GIMDNETWLTAQECYDYGLCDELVEEKEIAASINTELFAKYKNTPKELLNKTEKQNKPIKNTEKIEKDEEIEALIARVNN
ILKFEEERIYE

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17538017, Length=133, Percent_Identity=31.5789473684211, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI20129427, Length=135, Percent_Identity=31.8518518518519, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907
- InterPro:   IPR018215 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 28742; Mature: 28611

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANKKFWEVKNSTENENIGEAYIYGDIVSYKWDDTDTTAKSFKEDLDSLGDIDTLNIYIN
CCCCCEEECCCCCCCCCCCCEEEEECEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEEE
SPGGSVFQGQAIYNIIKRHKAKINIHVDGVAASIASVIAMAGNTIFMPKNSMMMIHNPWT
CCCCCEEEHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCEEEECCCCEEEEECCEE
FAYGNAKELRKQADDLDKIRESLIEAYLSKAGDKLSRETLIGIMDNETWLTAQECYDYGL
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCEEEHHHHHCCCH
CDELVEEKEIAASINTELFAKYKNTPKELLNKTEKQNKPIKNTEKIEKDEEIEALIARVN
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHH
NILKFEEERIYE
HHHHHHHHHCCC
>Mature Secondary Structure 
ANKKFWEVKNSTENENIGEAYIYGDIVSYKWDDTDTTAKSFKEDLDSLGDIDTLNIYIN
CCCCEEECCCCCCCCCCCCEEEEECEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEEE
SPGGSVFQGQAIYNIIKRHKAKINIHVDGVAASIASVIAMAGNTIFMPKNSMMMIHNPWT
CCCCCEEEHHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHCCCEEEECCCCEEEEECCEE
FAYGNAKELRKQADDLDKIRESLIEAYLSKAGDKLSRETLIGIMDNETWLTAQECYDYGL
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHEEEEECCCCEEEHHHHHCCCH
CDELVEEKEIAASINTELFAKYKNTPKELLNKTEKQNKPIKNTEKIEKDEEIEALIARVN
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHHHHH
NILKFEEERIYE
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA