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The map label for this gene is prpC [H]

Identifier: 153931990

GI number: 153931990

Start: 2512958

End: 2513707

Strand: Reverse

Name: prpC [H]

Synonym: CLB_2378

Alternate gene names: 153931990

Gene position: 2513707-2512958 (Counterclockwise)

Preceding gene: 153932990

Following gene: 153931038

Centisome position: 65.06

GC content: 30.13

Gene sequence:

>750_bases
ATGTTGGGGATACTATCTGATATAGGTAATGTTAGAGAGATAAATGAAGACTTTGTAGATTATTATCAAGGAGACCGATT
TAAAATATATATAGTAGCAGATGGAATGGGAGGTCATAATGCAGGAGAAGTAGCTAGTAAATTAGCAGTAGAAGAAACTA
TAGACTATATAAGATATTATGAAGATTTAAAAGATATGAAAACTTTACTTATAGATGCTATAGAATATGCCAATACAAAA
ATTTATAATTATGCAAAAGAAAAGGAAAAATTCAAAGGCATGGGAACTACCATAACTTGTTGCATATTAGATAATAATGG
AAATATGATTGTAGCTAACGTTGGAGATAGTTCTTGTTATATATTGGCTGAAGGTGGAGTTAAGAAAATAACAAAGGACC
ATTCCTATGTACAACAATTATTAGATGAAGGAACAATAACAAAGGAAGAGGCAAACACTCACCCTAATAAAAATGTAATT
ACTAGGGCATTAGGTACAAATTTATCTGTAAAAGTGGATACTTTTAATATAAAATTAGATGAAGTTTGTAAGGTATTACT
TTCTACAGATGGATTAACCAATTATGTTGATGAACAGGAAATGTGTGACATATTACTAAGAAATGGAAAAAACAATGAAG
AAACCTGCAAGCAGTTAGTAGAACTTAGCAAGTTAAAGGGTGGTAAAGATAACATATCCGTTATTTTGTTTGAAGGAGAG
TGTGAATATGATAGGAACCAAATTAGGTAA

Upstream 100 bases:

>100_bases
AGAAACAACTATAAGAAGAGAAATGGGGGCAGATATAAATGCTGCCTGTGGACAACTAAGAAGAAGTTATGTTTCAAAAT
AGAGCAAAGGGGTGGAAAAT

Downstream 100 bases:

>100_bases
TAGGTATGAACTTCTTGAAAAAGTTGGAGAGGGTGGTATGGCTACAGTTTATAAAGCTAAATGCCATTACCTAAATAGAT
TTGTCGCAATAAAGATATTA

Product: protein phosphatase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLGILSDIGNVREINEDFVDYYQGDRFKIYIVADGMGGHNAGEVASKLAVEETIDYIRYYEDLKDMKTLLIDAIEYANTK
IYNYAKEKEKFKGMGTTITCCILDNNGNMIVANVGDSSCYILAEGGVKKITKDHSYVQQLLDEGTITKEEANTHPNKNVI
TRALGTNLSVKVDTFNIKLDEVCKVLLSTDGLTNYVDEQEMCDILLRNGKNNEETCKQLVELSKLKGGKDNISVILFEGE
CEYDRNQIR

Sequences:

>Translated_249_residues
MLGILSDIGNVREINEDFVDYYQGDRFKIYIVADGMGGHNAGEVASKLAVEETIDYIRYYEDLKDMKTLLIDAIEYANTK
IYNYAKEKEKFKGMGTTITCCILDNNGNMIVANVGDSSCYILAEGGVKKITKDHSYVQQLLDEGTITKEEANTHPNKNVI
TRALGTNLSVKVDTFNIKLDEVCKVLLSTDGLTNYVDEQEMCDILLRNGKNNEETCKQLVELSKLKGGKDNISVILFEGE
CEYDRNQIR
>Mature_249_residues
MLGILSDIGNVREINEDFVDYYQGDRFKIYIVADGMGGHNAGEVASKLAVEETIDYIRYYEDLKDMKTLLIDAIEYANTK
IYNYAKEKEKFKGMGTTITCCILDNNGNMIVANVGDSSCYILAEGGVKKITKDHSYVQQLLDEGTITKEEANTHPNKNVI
TRALGTNLSVKVDTFNIKLDEVCKVLLSTDGLTNYVDEQEMCDILLRNGKNNEETCKQLVELSKLKGGKDNISVILFEGE
CEYDRNQIR

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 27988; Mature: 27988

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGILSDIGNVREINEDFVDYYQGDRFKIYIVADGMGGHNAGEVASKLAVEETIDYIRYY
CCCCHHHCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
EDLKDMKTLLIDAIEYANTKIYNYAKEKEKFKGMGTTITCCILDNNGNMIVANVGDSSCY
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCEEE
ILAEGGVKKITKDHSYVQQLLDEGTITKEEANTHPNKNVITRALGTNLSVKVDTFNIKLD
EEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCHH
EVCKVLLSTDGLTNYVDEQEMCDILLRNGKNNEETCKQLVELSKLKGGKDNISVILFEGE
HHHHHHHHCCCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCC
CEYDRNQIR
CCCCCCCCC
>Mature Secondary Structure
MLGILSDIGNVREINEDFVDYYQGDRFKIYIVADGMGGHNAGEVASKLAVEETIDYIRYY
CCCCHHHCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
EDLKDMKTLLIDAIEYANTKIYNYAKEKEKFKGMGTTITCCILDNNGNMIVANVGDSSCY
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEEECCCEEE
ILAEGGVKKITKDHSYVQQLLDEGTITKEEANTHPNKNVITRALGTNLSVKVDTFNIKLD
EEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEECCHH
EVCKVLLSTDGLTNYVDEQEMCDILLRNGKNNEETCKQLVELSKLKGGKDNISVILFEGE
HHHHHHHHCCCCHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCC
CEYDRNQIR
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]