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The map label for this gene is cidA2 [H]

Identifier: 152977352

GI number: 152977352

Start: 3736572

End: 3736940

Strand: Reverse

Name: cidA2 [H]

Synonym: Bcer98_3677

Alternate gene names: 152977352

Gene position: 3736940-3736572 (Counterclockwise)

Preceding gene: 152977353

Following gene: 152977351

Centisome position: 91.43

GC content: 33.88

Gene sequence:

>369_bases
ATGAAGTTTACAAAAGTTATTGTTCAAATCGTAGCTCTGTATGTGTTTTACATGTTAGGAACATGGATACAAGAAATATT
GGAAATTCCAATACCAGGAAGTTTGATTGGGATGTTTTTATTGCTTATTTTACTTGGCTTGAAAGTTCTTCCTGTGAAAT
GGTTTGATTTAGGAGCCGAAACACTCGTTGCCATTATGCCGTTTTTATTAATTCCACCAACGATTGGTTTAATGAATTAC
GGTGCTTTTTTTATGAGCAAAGGAATTTCTCTTTTCATTACAGTTGTAGCGAGCACATTTTTAATTATTATTGTCGCAGG
ACATACAGGACAATATCTTGCGACTAGAAAGGAAAAAGAGACAAGATGA

Upstream 100 bases:

>100_bases
GTGTTTTTCCTTGTCAAGTCGATAAATTGCAGGTTTTTACAATTTATACTATGATAAGGTTAGAAAAGGAAAGATCGTAT
AGACATGAGGGATGATGAAC

Downstream 100 bases:

>100_bases
GTAGTATATTAATCGGGATTGGTTGGGTTCTTCTGACAGTGTTCATATATCAATTATCTAAAATGATTTATAAGATATTG
CCAACGCCGTTTACGATTCC

Product: holin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 122; Mature: 122

Protein sequence:

>122_residues
MKFTKVIVQIVALYVFYMLGTWIQEILEIPIPGSLIGMFLLLILLGLKVLPVKWFDLGAETLVAIMPFLLIPPTIGLMNY
GAFFMSKGISLFITVVASTFLIIIVAGHTGQYLATRKEKETR

Sequences:

>Translated_122_residues
MKFTKVIVQIVALYVFYMLGTWIQEILEIPIPGSLIGMFLLLILLGLKVLPVKWFDLGAETLVAIMPFLLIPPTIGLMNY
GAFFMSKGISLFITVVASTFLIIIVAGHTGQYLATRKEKETR
>Mature_122_residues
MKFTKVIVQIVALYVFYMLGTWIQEILEIPIPGSLIGMFLLLILLGLKVLPVKWFDLGAETLVAIMPFLLIPPTIGLMNY
GAFFMSKGISLFITVVASTFLIIIVAGHTGQYLATRKEKETR

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788463, Length=108, Percent_Identity=29.6296296296296, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 13622; Mature: 13622

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFTKVIVQIVALYVFYMLGTWIQEILEIPIPGSLIGMFLLLILLGLKVLPVKWFDLGAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
TLVAIMPFLLIPPTIGLMNYGAFFMSKGISLFITVVASTFLIIIVAGHTGQYLATRKEKE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
TR
CC
>Mature Secondary Structure
MKFTKVIVQIVALYVFYMLGTWIQEILEIPIPGSLIGMFLLLILLGLKVLPVKWFDLGAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
TLVAIMPFLLIPPTIGLMNYGAFFMSKGISLFITVVASTFLIIIVAGHTGQYLATRKEKE
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCC
TR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]