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The map label for this gene is nprB [H]

Identifier: 152977299

GI number: 152977299

Start: 3679767

End: 3681203

Strand: Reverse

Name: nprB [H]

Synonym: Bcer98_3622

Alternate gene names: 152977299

Gene position: 3681203-3679767 (Counterclockwise)

Preceding gene: 152977300

Following gene: 152977291

Centisome position: 90.07

GC content: 35.21

Gene sequence:

>1437_bases
ATGTTCAAATTAGCCGGAAATGTAGAAAAACATTTCAAGATTGTTGGGGAAGAAAAAGATGAGAAGTCGGAGACAACTCA
TATTAAGCTAGTTGAGAAATATAATGACATTCCTGTGTATGGCTCAGATCAAACGATCACATTTGATAAAGAAAATAATG
TGAAGGCTTTTTTCGGACAAGTCATTCCAAATTTAGAGGATAAAAATATTCCGACTGCAACGAGCATTACGGATGAACAA
GCTGTAAACATTGCAAAGAAAAATATTGAAAAAGAAATTGGAAAAGTGAATCAATATGATGGTGTAAAAAAAGATTTATA
TGTGTATGAAAAAGACGGGAACTACTATCTTACTTATCTTGTAAAAGCATCTATTTCCAAACCAGCTCCAGGATATTGGC
ATTATTTTATTGATGCAACAAATGGAAATGTGATTGAGAAATATAATGCAATCGATTCTATTACAGGATTTGGATACGGT
GTATTAGGAAACAAAGCATCATTTGAAATTGCTCAAGATGAGAAAACAGGTGTATATAACTTGTTTGATGGGAAACGTGG
GCAAGGTGTTCATACATTTGACGCAAAAAATATGGACGAGAATATATTTATAATTTTATCACAATGGTTTGGTTATACAG
GAGAAGAAATAGAGAGTAAATCTAAGTTCTTTGAGGACAAAGCTGCAGTTGACGCACATGTAAATGCCGGAAAAGTATAT
GATTATTATAAAAAGACTTTTAATCGCAATTCTTTCGATAATAAAGGTGCAAAGCTCATTTCAGCTGTTCACGTAGGTGA
GGCTTGGAATAATGCGGCATGGAATGGCGTACAAATGGTATATGGTGATGGTGATGGAAAAACATTTATTCCATTATCTG
CAGGATTAGATGTAATTGGTCATGAATTAACACATGCTGTAACAGAATATACAGCGAATTTAGTTTATCAAAATGAATCA
GGTGCATTGAACGAATCGATATCGGATATTATGGGTGTTATGGTTGAGAAGAAAAACTGGGATATAGGGGCTGATATTTA
CACGCCTGATATTGAAGGAGATGCGCTTCGTTCTCTGAAAGATCCAGCTTCGATTCCAAATCCGTTAAAGCCAGGTGAAG
GGTATCCAGATCATTATAGCAAACGCTATGTAGGACCATATGATAACGGTGGTGTTCATATTAATAGTAGTATTAATAAT
AAAGCGGCATATTTAGTTTCTGAGGGCGGAGAGCATTACGGTGTAAAAGTAACTGGCATTGGCCGCGAAGCGACAGAAAA
AATTTACTATCATGCGCTTACGAAATATTTAACTGCAAATGCTGATTTTAAAATGATGCGTCAAGCTGCTCTGCAATCTG
CTGAAGATTTATATGGTGAAAATTCTAAAGCAGTACAAGCTGTAGACAAAGCTTATGAGTCAGTAGGCGTAAAATAA

Upstream 100 bases:

>100_bases
AAAATTTAAAACACCTGCTTACATAGGGGAAGAATGGAAAGCACCAGAAGGAGTAGATAAAAAAGAATCTGTCTTTCAAT
ATTTAGAGAGTAAGAAAGCA

Downstream 100 bases:

>100_bases
TAGGGGAAAAGACCTGACTTAGCTGAGTCAGGTCTTTTGTACATTAGTCACGAATGCCAAGAGCGATTTTTGCCATACGG
GACATACGTTCTTTAGACCA

Product: peptidase M4 thermolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MFKLAGNVEKHFKIVGEEKDEKSETTHIKLVEKYNDIPVYGSDQTITFDKENNVKAFFGQVIPNLEDKNIPTATSITDEQ
AVNIAKKNIEKEIGKVNQYDGVKKDLYVYEKDGNYYLTYLVKASISKPAPGYWHYFIDATNGNVIEKYNAIDSITGFGYG
VLGNKASFEIAQDEKTGVYNLFDGKRGQGVHTFDAKNMDENIFIILSQWFGYTGEEIESKSKFFEDKAAVDAHVNAGKVY
DYYKKTFNRNSFDNKGAKLISAVHVGEAWNNAAWNGVQMVYGDGDGKTFIPLSAGLDVIGHELTHAVTEYTANLVYQNES
GALNESISDIMGVMVEKKNWDIGADIYTPDIEGDALRSLKDPASIPNPLKPGEGYPDHYSKRYVGPYDNGGVHINSSINN
KAAYLVSEGGEHYGVKVTGIGREATEKIYYHALTKYLTANADFKMMRQAALQSAEDLYGENSKAVQAVDKAYESVGVK

Sequences:

>Translated_478_residues
MFKLAGNVEKHFKIVGEEKDEKSETTHIKLVEKYNDIPVYGSDQTITFDKENNVKAFFGQVIPNLEDKNIPTATSITDEQ
AVNIAKKNIEKEIGKVNQYDGVKKDLYVYEKDGNYYLTYLVKASISKPAPGYWHYFIDATNGNVIEKYNAIDSITGFGYG
VLGNKASFEIAQDEKTGVYNLFDGKRGQGVHTFDAKNMDENIFIILSQWFGYTGEEIESKSKFFEDKAAVDAHVNAGKVY
DYYKKTFNRNSFDNKGAKLISAVHVGEAWNNAAWNGVQMVYGDGDGKTFIPLSAGLDVIGHELTHAVTEYTANLVYQNES
GALNESISDIMGVMVEKKNWDIGADIYTPDIEGDALRSLKDPASIPNPLKPGEGYPDHYSKRYVGPYDNGGVHINSSINN
KAAYLVSEGGEHYGVKVTGIGREATEKIYYHALTKYLTANADFKMMRQAALQSAEDLYGENSKAVQAVDKAYESVGVK
>Mature_478_residues
MFKLAGNVEKHFKIVGEEKDEKSETTHIKLVEKYNDIPVYGSDQTITFDKENNVKAFFGQVIPNLEDKNIPTATSITDEQ
AVNIAKKNIEKEIGKVNQYDGVKKDLYVYEKDGNYYLTYLVKASISKPAPGYWHYFIDATNGNVIEKYNAIDSITGFGYG
VLGNKASFEIAQDEKTGVYNLFDGKRGQGVHTFDAKNMDENIFIILSQWFGYTGEEIESKSKFFEDKAAVDAHVNAGKVY
DYYKKTFNRNSFDNKGAKLISAVHVGEAWNNAAWNGVQMVYGDGDGKTFIPLSAGLDVIGHELTHAVTEYTANLVYQNES
GALNESISDIMGVMVEKKNWDIGADIYTPDIEGDALRSLKDPASIPNPLKPGEGYPDHYSKRYVGPYDNGGVHINSSINN
KAAYLVSEGGEHYGVKVTGIGREATEKIYYHALTKYLTANADFKMMRQAALQSAEDLYGENSKAVQAVDKAYESVGVK

Specific function: Unknown

COG id: COG3227

COG function: function code E; Zinc metalloprotease (elastase)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005075
- InterPro:   IPR013856
- InterPro:   IPR001570
- InterPro:   IPR011096 [H]

Pfam domain/function: PF07504 FTP; PF03413 PepSY; PF01447 Peptidase_M4; PF02868 Peptidase_M4_C [H]

EC number: NA

Molecular weight: Translated: 53090; Mature: 53090

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKLAGNVEKHFKIVGEEKDEKSETTHIKLVEKYNDIPVYGSDQTITFDKENNVKAFFGQ
CCCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCEECCCCEEEECCCCCHHHHHHH
VIPNLEDKNIPTATSITDEQAVNIAKKNIEKEIGKVNQYDGVKKDLYVYEKDGNYYLTYL
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEE
VKASISKPAPGYWHYFIDATNGNVIEKYNAIDSITGFGYGVLGNKASFEIAQDEKTGVYN
EEECCCCCCCCEEEEEEECCCCCEEEHHHHHHHHCCCCEEECCCCCEEEEECCCCCCEEE
LFDGKRGQGVHTFDAKNMDENIFIILSQWFGYTGEEIESKSKFFEDKAAVDAHVNAGKVY
ECCCCCCCCEEEECCCCCCCCEEEEEEHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHH
DYYKKTFNRNSFDNKGAKLISAVHVGEAWNNAAWNGVQMVYGDGDGKTFIPLSAGLDVIG
HHHHHHCCCCCCCCCCHHEEHHEECCCCCCCCCCCCEEEEEECCCCCEEEEECCCHHHHH
HELTHAVTEYTANLVYQNESGALNESISDIMGVMVEKKNWDIGADIYTPDIEGDALRSLK
HHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHEEECCCCCCCCEEECCCCCCHHHHHCC
DPASIPNPLKPGEGYPDHYSKRYVGPYDNGGVHINSSINNKAAYLVSEGGEHYGVKVTGI
CCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCEEEEEEEEC
GREATEKIYYHALTKYLTANADFKMMRQAALQSAEDLYGENSKAVQAVDKAYESVGVK
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFKLAGNVEKHFKIVGEEKDEKSETTHIKLVEKYNDIPVYGSDQTITFDKENNVKAFFGQ
CCCCCCCCCCCEEEECCCCCCCCCCEEEEEEECCCCCCEECCCCEEEECCCCCHHHHHHH
VIPNLEDKNIPTATSITDEQAVNIAKKNIEKEIGKVNQYDGVKKDLYVYEKDGNYYLTYL
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCEEEEEE
VKASISKPAPGYWHYFIDATNGNVIEKYNAIDSITGFGYGVLGNKASFEIAQDEKTGVYN
EEECCCCCCCCEEEEEEECCCCCEEEHHHHHHHHCCCCEEECCCCCEEEEECCCCCCEEE
LFDGKRGQGVHTFDAKNMDENIFIILSQWFGYTGEEIESKSKFFEDKAAVDAHVNAGKVY
ECCCCCCCCEEEECCCCCCCCEEEEEEHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHH
DYYKKTFNRNSFDNKGAKLISAVHVGEAWNNAAWNGVQMVYGDGDGKTFIPLSAGLDVIG
HHHHHHCCCCCCCCCCHHEEHHEECCCCCCCCCCCCEEEEEECCCCCEEEEECCCHHHHH
HELTHAVTEYTANLVYQNESGALNESISDIMGVMVEKKNWDIGADIYTPDIEGDALRSLK
HHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHEEECCCCCCCCEEECCCCCCHHHHHCC
DPASIPNPLKPGEGYPDHYSKRYVGPYDNGGVHINSSINNKAAYLVSEGGEHYGVKVTGI
CCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCEEEEEEEEC
GREATEKIYYHALTKYLTANADFKMMRQAALQSAEDLYGENSKAVQAVDKAYESVGVK
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1917867; 9025291; 9353931; 9384377 [H]