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The map label for this gene is csd [H]

Identifier: 152977256

GI number: 152977256

Start: 3636947

End: 3638167

Strand: Reverse

Name: csd [H]

Synonym: Bcer98_3577

Alternate gene names: 152977256

Gene position: 3638167-3636947 (Counterclockwise)

Preceding gene: 152977257

Following gene: 152977255

Centisome position: 89.02

GC content: 38.49

Gene sequence:

>1221_bases
ATGAATATTCATGAAATACGCAAACAGTTTCCAATTCTTGATCAAAAAGTGAACGGCAAACAACTTGTTTATTTCGATAG
TGCAGCAACTTCTCAAAAACCAATTCAAGTGATTGAAACGTTAGAACGTTATTATAAAGAATATAATTCTAACGTGCATC
GCGGTGTTCATACGCTCGGTACAAAAGCTACCGATGCGTATGAAGGTGCACGTGAGAAAGTTCGCAAGTTTATTAATGCG
AAATCAATGGAAGAAATTATTTTCACACGCGGAACGACAACTGCATTAAATACAGTAGCAGCAAGTTATGGCCGTGAAAA
TGTAAAAGAAGGCGATGAAATTGTTATCTCTTACATGGAGCACCATAGTAACATTATTCCGTGGCAACAAGTTGCAAAGA
AAACAGGGGCAACGTTAAAATATCTTCCGCTTCAGCCAGATGGAACAATCTCTATTGAAGATGCCCGTCAAACCATTACA
CCAAATACGAAAATTGTTTCTATCATGTATGTATCAAACGTACTTGGAACGATTAACCCTGTAAAAGAAATTGCAGAAAT
CGCTCATCAAAACGGTGCCATTATGGTCGTTGACGGTGCACAAAGTACACCTCATATGAAAGTAGATGTACAAGATTTAA
ACTGCGATTTCTATGCGTTATCCGCTCATAAAATGTGCGGGCCTACAGGTATCGGTGTATTATACGGTAAGAAGGAATTG
CTAGAAAATATGGAGCCAATTGAATTTGGCGGTGAAATGATTGATTTTGTAGATTTACAAGATTCTACATGGAAAGAGCT
TCCGTGGAAGTTTGAAGCCGGTACACCGATTATCGGTAATGCAATCGGACTTGGAGCAGCAATTGATTTCCTAGAAGAAA
TCGGTCTTGATAATATTGAAAAGCATGAACATGAATTAGCGCAGTACGCTTTAGAAAGACTATCGGAAGTAGATGGCGTT
ACAATTTATGGTCCAAAGCATCGCGCTGGTCTTGTTACATTTAATATTGATGAAGTACATCCACACGATGTTGCGACAGT
ACTAGATGTAGAAGGCATTGCGGTTCGCGCAGGACATCACTGTGCACAACCGCTTATGAAGTGGCTAAAAGCTTCTTCTA
CAGCACGTGCAAGCTTCTATTTATATAATACAAAAGAAGAAATTGATACATTTGTTGAAGCGCTAACGAAAACAAAGGAG
TATTTCACAAATGTCTTTTAA

Upstream 100 bases:

>100_bases
GCTTAGTCATCCATGGATTCTTAGCACCTGTAGTAAATGAGCTTCCAATTGAAGGAGTAAAAACACAGCTTGTTGAGGTA
ATTGAAAGGAAAGTTCGCTA

Downstream 100 bases:

>100_bases
TAATTTAGATACGTTATATCGTCAAGTTATTATGGATCATTATAAGAATCCACGTAACCATGGCGTGTTAGAAGATAGTG
TTACAGTTAACTTAAACAAC

Product: SufS subfamily cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNIHEIRKQFPILDQKVNGKQLVYFDSAATSQKPIQVIETLERYYKEYNSNVHRGVHTLGTKATDAYEGAREKVRKFINA
KSMEEIIFTRGTTTALNTVAASYGRENVKEGDEIVISYMEHHSNIIPWQQVAKKTGATLKYLPLQPDGTISIEDARQTIT
PNTKIVSIMYVSNVLGTINPVKEIAEIAHQNGAIMVVDGAQSTPHMKVDVQDLNCDFYALSAHKMCGPTGIGVLYGKKEL
LENMEPIEFGGEMIDFVDLQDSTWKELPWKFEAGTPIIGNAIGLGAAIDFLEEIGLDNIEKHEHELAQYALERLSEVDGV
TIYGPKHRAGLVTFNIDEVHPHDVATVLDVEGIAVRAGHHCAQPLMKWLKASSTARASFYLYNTKEEIDTFVEALTKTKE
YFTNVF

Sequences:

>Translated_406_residues
MNIHEIRKQFPILDQKVNGKQLVYFDSAATSQKPIQVIETLERYYKEYNSNVHRGVHTLGTKATDAYEGAREKVRKFINA
KSMEEIIFTRGTTTALNTVAASYGRENVKEGDEIVISYMEHHSNIIPWQQVAKKTGATLKYLPLQPDGTISIEDARQTIT
PNTKIVSIMYVSNVLGTINPVKEIAEIAHQNGAIMVVDGAQSTPHMKVDVQDLNCDFYALSAHKMCGPTGIGVLYGKKEL
LENMEPIEFGGEMIDFVDLQDSTWKELPWKFEAGTPIIGNAIGLGAAIDFLEEIGLDNIEKHEHELAQYALERLSEVDGV
TIYGPKHRAGLVTFNIDEVHPHDVATVLDVEGIAVRAGHHCAQPLMKWLKASSTARASFYLYNTKEEIDTFVEALTKTKE
YFTNVF
>Mature_406_residues
MNIHEIRKQFPILDQKVNGKQLVYFDSAATSQKPIQVIETLERYYKEYNSNVHRGVHTLGTKATDAYEGAREKVRKFINA
KSMEEIIFTRGTTTALNTVAASYGRENVKEGDEIVISYMEHHSNIIPWQQVAKKTGATLKYLPLQPDGTISIEDARQTIT
PNTKIVSIMYVSNVLGTINPVKEIAEIAHQNGAIMVVDGAQSTPHMKVDVQDLNCDFYALSAHKMCGPTGIGVLYGKKEL
LENMEPIEFGGEMIDFVDLQDSTWKELPWKFEAGTPIIGNAIGLGAAIDFLEEIGLDNIEKHEHELAQYALERLSEVDGV
TIYGPKHRAGLVTFNIDEVHPHDVATVLDVEGIAVRAGHHCAQPLMKWLKASSTARASFYLYNTKEEIDTFVEALTKTKE
YFTNVF

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=386, Percent_Identity=26.4248704663212, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI156713448, Length=322, Percent_Identity=28.2608695652174, Blast_Score=89, Evalue=6e-18,
Organism=Escherichia coli, GI1787970, Length=398, Percent_Identity=48.7437185929648, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1789175, Length=404, Percent_Identity=40.8415841584158, Blast_Score=316, Evalue=1e-87,
Organism=Escherichia coli, GI48994898, Length=389, Percent_Identity=23.9074550128535, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25143064, Length=343, Percent_Identity=26.8221574344023, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193211090, Length=419, Percent_Identity=24.1050119331742, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17533177, Length=334, Percent_Identity=23.6526946107784, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319831, Length=397, Percent_Identity=26.9521410579345, Blast_Score=140, Evalue=4e-34,
Organism=Drosophila melanogaster, GI20129463, Length=318, Percent_Identity=30.188679245283, Blast_Score=129, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45390; Mature: 45390

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEIRKQFPILDQKVNGKQLVYFDSAATSQKPIQVIETLERYYKEYNSNVHRGVHTLG
CCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHC
TKATDAYEGAREKVRKFINAKSMEEIIFTRGTTTALNTVAASYGRENVKEGDEIVISYME
CCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCHHHCCCCHHHHHHHHH
HHSNIIPWQQVAKKTGATLKYLPLQPDGTISIEDARQTITPNTKIVSIMYVSNVLGTINP
HCCCCCCHHHHHHHHCCEEEEEECCCCCCEEECCHHHHCCCCCEEEEEEEHHHHHHCCHH
VKEIAEIAHQNGAIMVVDGAQSTPHMKVDVQDLNCDFYALSAHKMCGPTGIGVLYGKKEL
HHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCEEEECCHHH
LENMEPIEFGGEMIDFVDLQDSTWKELPWKFEAGTPIIGNAIGLGAAIDFLEEIGLDNIE
HCCCCCHHHCCCEEEEEECCCCCHHHCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHH
KHEHELAQYALERLSEVDGVTIYGPKHRAGLVTFNIDEVHPHDVATVLDVEGIAVRAGHH
HHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCCCCCHHEEEECCCEEEECCHH
CAQPLMKWLKASSTARASFYLYNTKEEIDTFVEALTKTKEYFTNVF
HHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIHEIRKQFPILDQKVNGKQLVYFDSAATSQKPIQVIETLERYYKEYNSNVHRGVHTLG
CCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHC
TKATDAYEGAREKVRKFINAKSMEEIIFTRGTTTALNTVAASYGRENVKEGDEIVISYME
CCCHHHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCHHHCCCCHHHHHHHHH
HHSNIIPWQQVAKKTGATLKYLPLQPDGTISIEDARQTITPNTKIVSIMYVSNVLGTINP
HCCCCCCHHHHHHHHCCEEEEEECCCCCCEEECCHHHHCCCCCEEEEEEEHHHHHHCCHH
VKEIAEIAHQNGAIMVVDGAQSTPHMKVDVQDLNCDFYALSAHKMCGPTGIGVLYGKKEL
HHHHHHHHHCCCCEEEEECCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCEEEECCHHH
LENMEPIEFGGEMIDFVDLQDSTWKELPWKFEAGTPIIGNAIGLGAAIDFLEEIGLDNIE
HCCCCCHHHCCCEEEEEECCCCCHHHCCEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHH
KHEHELAQYALERLSEVDGVTIYGPKHRAGLVTFNIDEVHPHDVATVLDVEGIAVRAGHH
HHHHHHHHHHHHHHHHCCCEEEECCCCCCEEEEEECCCCCCCCHHEEEECCCEEEECCHH
CAQPLMKWLKASSTARASFYLYNTKEEIDTFVEALTKTKEYFTNVF
HHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]