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The map label for this gene is coaE [H]

Identifier: 152976966

GI number: 152976966

Start: 3335808

End: 3336410

Strand: Reverse

Name: coaE [H]

Synonym: Bcer98_3269

Alternate gene names: 152976966

Gene position: 3336410-3335808 (Counterclockwise)

Preceding gene: 152976967

Following gene: 152976965

Centisome position: 81.63

GC content: 35.82

Gene sequence:

>603_bases
ATGACAGTTGTAATTGGACTAACAGGAGGTATTGCAAGCGGAAAAAGCACCGTTTCGCAAATGTTACGTGAATGTAACAT
TCCTGTTATTGATGCGGATATTGTTGCAAGAGAGGTTGTAGAACAAGGGAAACCAGCATATAACAAAATTGTAGAGGTTT
TTGGAAAAGAAATATTACAAGAGGATGGAGAATTAAATCGTCAAAAGCTTGGGAGTATTGTGTTTCATAATGAAGAAAAA
CGAATGCAATTAAATGGAATTGTGCATCCTGCTGTACGCAAAGAGATGAATGAACAAAAGGATCGGTACATAAAAGAAGG
AGTACAAGCGGTTGTGTTAGATATTCCTCTTTTGTTTGAAGGGAATTTAACAAATCTTGTAGATTATGTTTTAGTTGTAG
CAGTTTCACCGAGTATACAGTTAGAACGTTTAATGAAGCGAAATGGTTTTTCAGAAGAAGAAGCGAAAGTGAGGATTCAT
TCACAAATGCCGCTAGCAGAAAAGATAACATTAGGAGATAAAGTGATCTATAATGATGGCACAATTGCTGAGACAAAAGA
ACAATTGCAGCGGATTTTAAAGGAATGGAGCATGATTAACTAA

Upstream 100 bases:

>100_bases
TTACTTTCCTGCCTGGAGTGTTACTGATTATTATTGGACTTTGGAAAATATAGAGGCGTGGAACATGAGTTTCACGCCTT
ATTGTTAAGGAGGAAAACGA

Downstream 100 bases:

>100_bases
AAAATTTTGAAATTAATGAAAATGTTTAGTGACATATTCCTTTTTTATGTTATACTATTATTGGGATTGGAGATAAATAG
TATAACGCATTCAAGGGGGA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MTVVIGLTGGIASGKSTVSQMLRECNIPVIDADIVAREVVEQGKPAYNKIVEVFGKEILQEDGELNRQKLGSIVFHNEEK
RMQLNGIVHPAVRKEMNEQKDRYIKEGVQAVVLDIPLLFEGNLTNLVDYVLVVAVSPSIQLERLMKRNGFSEEEAKVRIH
SQMPLAEKITLGDKVIYNDGTIAETKEQLQRILKEWSMIN

Sequences:

>Translated_200_residues
MTVVIGLTGGIASGKSTVSQMLRECNIPVIDADIVAREVVEQGKPAYNKIVEVFGKEILQEDGELNRQKLGSIVFHNEEK
RMQLNGIVHPAVRKEMNEQKDRYIKEGVQAVVLDIPLLFEGNLTNLVDYVLVVAVSPSIQLERLMKRNGFSEEEAKVRIH
SQMPLAEKITLGDKVIYNDGTIAETKEQLQRILKEWSMIN
>Mature_199_residues
TVVIGLTGGIASGKSTVSQMLRECNIPVIDADIVAREVVEQGKPAYNKIVEVFGKEILQEDGELNRQKLGSIVFHNEEKR
MQLNGIVHPAVRKEMNEQKDRYIKEGVQAVVLDIPLLFEGNLTNLVDYVLVVAVSPSIQLERLMKRNGFSEEEAKVRIHS
QMPLAEKITLGDKVIYNDGTIAETKEQLQRILKEWSMIN

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=187, Percent_Identity=44.3850267379679, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI191252795, Length=187, Percent_Identity=44.3850267379679, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI110227607, Length=197, Percent_Identity=34.5177664974619, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI110227605, Length=197, Percent_Identity=34.5177664974619, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI110227603, Length=197, Percent_Identity=34.5177664974619, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI110227601, Length=197, Percent_Identity=34.5177664974619, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI205277394, Length=197, Percent_Identity=34.5177664974619, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1786292, Length=196, Percent_Identity=36.734693877551, Blast_Score=121, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17554944, Length=195, Percent_Identity=41.025641025641, Blast_Score=155, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI25143409, Length=193, Percent_Identity=32.1243523316062, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320402, Length=198, Percent_Identity=45.959595959596, Blast_Score=171, Evalue=8e-44,
Organism=Drosophila melanogaster, GI24644728, Length=190, Percent_Identity=42.6315789473684, Blast_Score=158, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24658602, Length=200, Percent_Identity=37, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22498; Mature: 22367

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVVIGLTGGIASGKSTVSQMLRECNIPVIDADIVAREVVEQGKPAYNKIVEVFGKEILQ
CEEEEEECCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EDGELNRQKLGSIVFHNEEKRMQLNGIVHPAVRKEMNEQKDRYIKEGVQAVVLDIPLLFE
CCCCCCHHHHHHHHEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEC
GNLTNLVDYVLVVAVSPSIQLERLMKRNGFSEEEAKVRIHSQMPLAEKITLGDKVIYNDG
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHEEECCCCCCHHHCCCCCEEEECCC
TIAETKEQLQRILKEWSMIN
CHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVVIGLTGGIASGKSTVSQMLRECNIPVIDADIVAREVVEQGKPAYNKIVEVFGKEILQ
EEEEEECCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
EDGELNRQKLGSIVFHNEEKRMQLNGIVHPAVRKEMNEQKDRYIKEGVQAVVLDIPLLFE
CCCCCCHHHHHHHHEECCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEC
GNLTNLVDYVLVVAVSPSIQLERLMKRNGFSEEEAKVRIHSQMPLAEKITLGDKVIYNDG
CCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHEEECCCCCCHHHCCCCCEEEECCC
TIAETKEQLQRILKEWSMIN
CHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]