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The map label for this gene is infC [H]

Identifier: 152976958

GI number: 152976958

Start: 3326380

End: 3326967

Strand: Reverse

Name: infC [H]

Synonym: Bcer98_3261

Alternate gene names: 152976958

Gene position: 3326967-3326380 (Counterclockwise)

Preceding gene: 152976959

Following gene: 152976957

Centisome position: 81.4

GC content: 37.41

Gene sequence:

>588_bases
ATGCCCGCACTTTTTTTGTTCGGGTTCTATGACTGCAAACATATTCTGAGAAAATCTTGGAGGTGGCTTACTATTAGCAA
GGATATGATGATTAACGAGCAAATTCGTGCTCGTGAAGTACGTTTAGTTGGTGCAAATGGTGATCAACTTGGTATTAAGT
CTCGTAATGACGCTTTAGATATGGCTGCAAATCTTAATCTTGATTTAGTATTAGTTGCTCCAAATGCGAAACCGCCAGTA
TGCCGCATTATGGATTATGGTAAATTCCGCTTTGAGCAACAAAAGAAAGAAAAAGAGCAGCGTAAAAATCAAAAAGTAAT
TAGCATGAAAGAAGTTCGTTTAAGTCCAACAATTGATGAACATGACTTTAACACAAAACTTCGCAACGCTCTTAAATTTT
TAGGTAAAGGCGACAAAGTTAAAGCATCTATTCGCTTTAAAGGACGTGCCATTACTCATAAAGAAATCGGTCAACGTGTC
TTAGATCGTTTCGCGGAAGCTTGTGCTGAAGTAGGAACAATTGAATCTAAGCCTAAAATGGAAGGACGTAGCATGTTCTT
AATTTTAGCACCGAAAAACGATAAGTAA

Upstream 100 bases:

>100_bases
GTAGAGCAAGTAGAAGCACCCGCTTCTCACCTGATTGACGCATTCGCAGTTAACAGGTAAATGTATTTCTTACGTAAGAT
AGTACAAGTGTGGGTGTCGT

Downstream 100 bases:

>100_bases
TAGATAGAGGAGGAAATACCTATGCCTAAACAAAAAACTCATCGCGGCGCTGCAAAGCGTTTCAAAAAAACTGGATCTGG
TAAACTTAAACGTGATCACG

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MPALFLFGFYDCKHILRKSWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALDMAANLNLDLVLVAPNAKPPV
CRIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNALKFLGKGDKVKASIRFKGRAITHKEIGQRV
LDRFAEACAEVGTIESKPKMEGRSMFLILAPKNDK

Sequences:

>Translated_195_residues
MPALFLFGFYDCKHILRKSWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALDMAANLNLDLVLVAPNAKPPV
CRIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNALKFLGKGDKVKASIRFKGRAITHKEIGQRV
LDRFAEACAEVGTIESKPKMEGRSMFLILAPKNDK
>Mature_194_residues
PALFLFGFYDCKHILRKSWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALDMAANLNLDLVLVAPNAKPPVC
RIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDEHDFNTKLRNALKFLGKGDKVKASIRFKGRAITHKEIGQRVL
DRFAEACAEVGTIESKPKMEGRSMFLILAPKNDK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=176, Percent_Identity=48.8636363636364, Blast_Score=160, Evalue=4e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 22450; Mature: 22318

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALFLFGFYDCKHILRKSWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALD
CCEEEEEHHHHHHHHHHCCCEEEEEECCHHCCCCCCEEEEEEECCCCCEECCCCCCCHHH
MAANLNLDLVLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDE
HHCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEHEEEEECCCCCC
HDFNTKLRNALKFLGKGDKVKASIRFKGRAITHKEIGQRVLDRFAEACAEVGTIESKPKM
CCCHHHHHHHHHHHCCCCEEEEEEEECCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EGRSMFLILAPKNDK
CCCEEEEEEECCCCC
>Mature Secondary Structure 
PALFLFGFYDCKHILRKSWRWLTISKDMMINEQIRAREVRLVGANGDQLGIKSRNDALD
CEEEEEHHHHHHHHHHCCCEEEEEECCHHCCCCCCEEEEEEECCCCCEECCCCCCCHHH
MAANLNLDLVLVAPNAKPPVCRIMDYGKFRFEQQKKEKEQRKNQKVISMKEVRLSPTIDE
HHCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEHEEEEECCCCCC
HDFNTKLRNALKFLGKGDKVKASIRFKGRAITHKEIGQRVLDRFAEACAEVGTIESKPKM
CCCHHHHHHHHHHHCCCCEEEEEEEECCCEECHHHHHHHHHHHHHHHHHHHCCCCCCCCC
EGRSMFLILAPKNDK
CCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]