BacMap

Definition	Bacillus cereus subsp. cytotoxis NVH 391-98, complete genome.
Accession	NC_009674
Length	4,087,024

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The map label for this gene is fadB [H]

Identifier: 152976922

GI number: 152976922

Start: 3290622

End: 3291395

Strand: Reverse

Name: fadB [H]

Synonym: Bcer98_3224

Alternate gene names: 152976922

Gene position: 3291395-3290622 (Counterclockwise)

Preceding gene: 152976923

Following gene: 152976921

Centisome position: 80.53

GC content: 42.25

Gene sequence:

>774_bases
TTGAAATTCCTATCTGTAACAGTTGAAGACCATATTGCAGTGGTAACGTTCAATCATCCACCAGCTAATGCAATGTCTTC
GCAAGTCATGCATGACGTAACTGAATTAATTGATCAAGTTGAAAAAGACGACAATATTCGGGTTGTTGTTCTTCATGGGG
AAGGTCGCTTCTTTTCTGCAGGGGCAGATATTAAGGAATTTACTTCTGTTGAGGACGCAAAGCAAGCGACAGAGCTGGCG
CAGCTTGGACAAGTTACATTTGAGCGCGTAGAAAAGTGTTCAAAACCAGTTATTGCAGCAATTCATGGAGCGGCACTTGG
CGGTGGTCTTGAATTTGCTATGTCTTGTCATATGCGTTTTGCAACTGAAAGTGCCAAGCTTGGTTTACCTGAGTTAACAT
TAGGATTAATCCCTGGATTTGCAGGAACACAGCGATTACCTCGTTATGTTGGAAAAGCAAAAGCTTGTGAAATGATGTTA
ACAAGCACGCCGATTACTGGCGCACAAGCATTAGAATGGGGTCTTGTAAATGGAGTGTTTTCTGAAGAATCCTTGTTAGA
AGAGACGATGAAAATTGCAAAACAAATTGCAGGGAAAAGTCCTGCAACAGTTCGTGCTGTGCTAGAGTTATTGCAAACGA
CGAAATCACCTCAATATTATGAGGGTGTGCAACACGAAGCGCAAATCTTTGGAGAAGTATTTACAAGCGAGGATGGAAGA
GAAGGTGTAGCGGCATTTTTAGAAAAACGCAAGCCTTCATTTAGCGGTAGGTAG

Upstream 100 bases:

>100_bases
TAATGAGCGATCATAAATATGATTTGGTCGCACTTTCAAAAACGGTACATGAGCTACTTGTTTTAGCTTGTGGCTATCGT
CAATAATGGGAGGGATCAAG

Downstream 100 bases:

>100_bases
TACATTATTTTTTTAATATAAATTAACAGAATATTTAAATTGATGAAATCTTTCTAAAAAATAAGGGGGTAAATGGAATG
AACATCTACGTACTCATGAA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKFLSVTVEDHIAVVTFNHPPANAMSSQVMHDVTELIDQVEKDDNIRVVVLHGEGRFFSAGADIKEFTSVEDAKQATELA
QLGQVTFERVEKCSKPVIAAIHGAALGGGLEFAMSCHMRFATESAKLGLPELTLGLIPGFAGTQRLPRYVGKAKACEMML
TSTPITGAQALEWGLVNGVFSEESLLEETMKIAKQIAGKSPATVRAVLELLQTTKSPQYYEGVQHEAQIFGEVFTSEDGR
EGVAAFLEKRKPSFSGR

Sequences:

>Translated_257_residues
MKFLSVTVEDHIAVVTFNHPPANAMSSQVMHDVTELIDQVEKDDNIRVVVLHGEGRFFSAGADIKEFTSVEDAKQATELA
QLGQVTFERVEKCSKPVIAAIHGAALGGGLEFAMSCHMRFATESAKLGLPELTLGLIPGFAGTQRLPRYVGKAKACEMML
TSTPITGAQALEWGLVNGVFSEESLLEETMKIAKQIAGKSPATVRAVLELLQTTKSPQYYEGVQHEAQIFGEVFTSEDGR
EGVAAFLEKRKPSFSGR
>Mature_257_residues
MKFLSVTVEDHIAVVTFNHPPANAMSSQVMHDVTELIDQVEKDDNIRVVVLHGEGRFFSAGADIKEFTSVEDAKQATELA
QLGQVTFERVEKCSKPVIAAIHGAALGGGLEFAMSCHMRFATESAKLGLPELTLGLIPGFAGTQRLPRYVGKAKACEMML
TSTPITGAQALEWGLVNGVFSEESLLEETMKIAKQIAGKSPATVRAVLELLQTTKSPQYYEGVQHEAQIFGEVFTSEDGR
EGVAAFLEKRKPSFSGR

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=249, Percent_Identity=36.144578313253, Blast_Score=154, Evalue=9e-38,
Organism=Homo sapiens, GI20127408, Length=179, Percent_Identity=39.6648044692737, Blast_Score=130, Evalue=8e-31,
Organism=Homo sapiens, GI68989263, Length=206, Percent_Identity=34.9514563106796, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI70995211, Length=258, Percent_Identity=27.5193798449612, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI31542718, Length=243, Percent_Identity=30.4526748971193, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI4502327, Length=239, Percent_Identity=29.2887029288703, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI157694516, Length=240, Percent_Identity=25.8333333333333, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI213417737, Length=240, Percent_Identity=25.8333333333333, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI260274832, Length=252, Percent_Identity=26.1904761904762, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI45643119, Length=252, Percent_Identity=26.1904761904762, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI260275230, Length=252, Percent_Identity=26.1904761904762, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI221136756, Length=236, Percent_Identity=24.5762711864407, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI221136753, Length=236, Percent_Identity=24.5762711864407, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI150378541, Length=255, Percent_Identity=28.2352941176471, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI221307494, Length=236, Percent_Identity=24.5762711864407, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI25453481, Length=238, Percent_Identity=22.6890756302521, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI51538573, Length=238, Percent_Identity=22.6890756302521, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI157694520, Length=223, Percent_Identity=26.0089686098655, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI37594471, Length=214, Percent_Identity=29.9065420560748, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI37594469, Length=213, Percent_Identity=30.0469483568075, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI4757966, Length=227, Percent_Identity=22.9074889867841, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI51538581, Length=227, Percent_Identity=22.9074889867841, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI261878539, Length=109, Percent_Identity=36.697247706422, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI4757968, Length=238, Percent_Identity=22.2689075630252, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI49355787, Length=238, Percent_Identity=22.2689075630252, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI116235487, Length=231, Percent_Identity=23.8095238095238, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI62530384, Length=177, Percent_Identity=27.683615819209, Blast_Score=68, Evalue=7e-12,
Organism=Escherichia coli, GI1787659, Length=258, Percent_Identity=37.2093023255814, Blast_Score=177, Evalue=6e-46,
Organism=Escherichia coli, GI1788682, Length=264, Percent_Identity=35.6060606060606, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI221142681, Length=259, Percent_Identity=31.6602316602317, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790281, Length=191, Percent_Identity=34.0314136125654, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI87082183, Length=263, Percent_Identity=29.6577946768061, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=31.2977099236641, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1788597, Length=250, Percent_Identity=31.2, Blast_Score=110, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25145438, Length=248, Percent_Identity=39.5161290322581, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17554946, Length=258, Percent_Identity=36.046511627907, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17540714, Length=199, Percent_Identity=38.1909547738693, Blast_Score=134, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI17534483, Length=263, Percent_Identity=28.8973384030418, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17558304, Length=174, Percent_Identity=35.632183908046, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI25144276, Length=175, Percent_Identity=38.8571428571429, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17508951, Length=175, Percent_Identity=38.8571428571429, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17508953, Length=175, Percent_Identity=38.8571428571429, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17560910, Length=222, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17536985, Length=262, Percent_Identity=24.8091603053435, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17540306, Length=247, Percent_Identity=27.1255060728745, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17535521, Length=253, Percent_Identity=24.5059288537549, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17549921, Length=234, Percent_Identity=26.0683760683761, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25141363, Length=235, Percent_Identity=23.8297872340426, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25144160, Length=215, Percent_Identity=26.9767441860465, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25144157, Length=215, Percent_Identity=26.9767441860465, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=196, Percent_Identity=29.0816326530612, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129971, Length=250, Percent_Identity=38.4, Blast_Score=164, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24653477, Length=250, Percent_Identity=38.4, Blast_Score=164, Evalue=4e-41,
Organism=Drosophila melanogaster, GI24653139, Length=251, Percent_Identity=36.2549800796813, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI19920382, Length=253, Percent_Identity=31.2252964426877, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI19921000, Length=210, Percent_Identity=35.2380952380952, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24583077, Length=210, Percent_Identity=35.2380952380952, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24583079, Length=210, Percent_Identity=35.2380952380952, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19922422, Length=263, Percent_Identity=29.6577946768061, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357171, Length=259, Percent_Identity=29.7297297297297, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24650670, Length=250, Percent_Identity=30.4, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24654903, Length=189, Percent_Identity=26.4550264550265, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24583165, Length=138, Percent_Identity=31.1594202898551, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI19921018, Length=194, Percent_Identity=28.8659793814433, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27873; Mature: 27873

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLSVTVEDHIAVVTFNHPPANAMSSQVMHDVTELIDQVEKDDNIRVVVLHGEGRFFSA
CCEEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEC
GADIKEFTSVEDAKQATELAQLGQVTFERVEKCSKPVIAAIHGAALGGGLEFAMSCHMRF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHH
ATESAKLGLPELTLGLIPGFAGTQRLPRYVGKAKACEMMLTSTPITGAQALEWGLVNGVF
HCCHHCCCCCHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCCC
SEESLLEETMKIAKQIAGKSPATVRAVLELLQTTKSPQYYEGVQHEAQIFGEVFTSEDGR
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCH
EGVAAFLEKRKPSFSGR
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKFLSVTVEDHIAVVTFNHPPANAMSSQVMHDVTELIDQVEKDDNIRVVVLHGEGRFFSA
CCEEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEC
GADIKEFTSVEDAKQATELAQLGQVTFERVEKCSKPVIAAIHGAALGGGLEFAMSCHMRF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHH
ATESAKLGLPELTLGLIPGFAGTQRLPRYVGKAKACEMMLTSTPITGAQALEWGLVNGVF
HCCHHCCCCCHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCCC
SEESLLEETMKIAKQIAGKSPATVRAVLELLQTTKSPQYYEGVQHEAQIFGEVFTSEDGR
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCH
EGVAAFLEKRKPSFSGR
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]