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The map label for this gene is obgE [H]

Identifier: 152976856

GI number: 152976856

Start: 3205799

End: 3207085

Strand: Reverse

Name: obgE [H]

Synonym: Bcer98_3155

Alternate gene names: 152976856

Gene position: 3207085-3205799 (Counterclockwise)

Preceding gene: 152976857

Following gene: 152976855

Centisome position: 78.47

GC content: 42.04

Gene sequence:

>1287_bases
ATGTTTGTAGATCAGGTCAAAATATACGTAAAAGCTGGAGACGGCGGAAACGGGATGGTTGCGTATCGTCGTGAAAAGTA
TGTTCCAAAAGGTGGTCCAGCAGGTGGAGACGGTGGTAAAGGTGCAGATGTTGTTTTCCAAGTAGATGAAGGATTACGTA
CATTAATGGATTTTCGCTATCAACGTCATTTCAAGGCTGACCGCGGGCAACATGGTATGAGCAAAAACCAACATGGCCGT
AAAGCTGATGATTTAATCGTAAAAGTTCCGCCAGGGACAGTTGTGAAAGATGTGAAAACGGGTCATATTCTTGCTGATTT
AGTCACACATGGACAATCAGCAGTTATTGCTAAAGGTGGCCGTGGTGGTCGTGGTAACTCACGTTTTGCGACTCCTACAA
ATCCAGCTCCAGAAATTGCTGAGAATGGTGAACCGGGCCAAGAACGTGATGTTATCTTAGAACTGAAAGTGTTAGCCGAT
GTTGGACTTGTTGGATTCCCTAGCGTTGGGAAATCAACGCTATTATCTGTCGTATCATCAGCGCGTCCGAAGATTGCAGA
ATATCACTTTACAACCATTGTGCCAAACCTTGGTGTTGTCGAAACAGGTGATAATCGCAGCTTCGTTATGGCTGACCTTC
CAGGGCTCATTGAAGGTGCCCATGCAGGTGTTGGACTTGGGCATCAGTTCTTGCGTCATATTGAGCGTACACGCGTTATC
GTACATGTCATTGATATGTCTGGTTTAGAAGGGCGCGATCCATATGAGGATTATGTCACAATTAATAATGAATTAAAAGA
ATATAATCTGCGTTTAACAGAGCGTCCACAAGTTGTTGTTGCAAATAAAATGGATATGCCAGATGCAGAAGAAAACTTAC
AAGCATTTAAAGAGAAAGTGGGAGACGAAGTAAAAATCTTCCCAATCTCAGCTGTAACAAAACAAGGGGTTCGTGACTTA
CTGTTTGAAGTAGCGAACTTATTAGAAACAACACCAGAATTTCCAGTACATGAAGTTGTGGATGAGTCGGAAGCAAGTGT
AATGTACAAATTTGAGACGGAAGGTGTTAAATTTGAAATTACACGTGAAAGTGATGGCACGTTTGTTATCTCTGGTTATG
ATATCGAGAAAACATTCAAAATGACAGACTTCTCACGTGATGAATCTGTACGTCGTTTCGCTCGTCAAATGCGCGGAATG
GGTATTGATGAAGCGCTTCGTGCACGTGGTGCAAAAGATGGAGATATTGTAAAAATTCTTGAATATGAATTTGAATTTAT
CGACTAA

Upstream 100 bases:

>100_bases
CTTGCAAATGAAAAAAATGAATGGTGTTCCATTTTCTATACAGTCCGAGATGATGAAGTCTCGGTTATATTACAACCAAT
TGAAAAAGTGTGGTGAAATA

Downstream 100 bases:

>100_bases
GACTGCCGAAATATGGCAGTCTTTTTTTATTGCGATAGTAAGATTTATAAAGGAAAAAATCCCCACCAAATAAATTTTCA
ATTTATAATGGAAAAAGGAG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg [H]

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MFVDQVKIYVKAGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFQVDEGLRTLMDFRYQRHFKADRGQHGMSKNQHGR
KADDLIVKVPPGTVVKDVKTGHILADLVTHGQSAVIAKGGRGGRGNSRFATPTNPAPEIAENGEPGQERDVILELKVLAD
VGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTKQGVRDL
LFEVANLLETTPEFPVHEVVDESEASVMYKFETEGVKFEITRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGM
GIDEALRARGAKDGDIVKILEYEFEFID

Sequences:

>Translated_428_residues
MFVDQVKIYVKAGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFQVDEGLRTLMDFRYQRHFKADRGQHGMSKNQHGR
KADDLIVKVPPGTVVKDVKTGHILADLVTHGQSAVIAKGGRGGRGNSRFATPTNPAPEIAENGEPGQERDVILELKVLAD
VGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTKQGVRDL
LFEVANLLETTPEFPVHEVVDESEASVMYKFETEGVKFEITRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGM
GIDEALRARGAKDGDIVKILEYEFEFID
>Mature_428_residues
MFVDQVKIYVKAGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFQVDEGLRTLMDFRYQRHFKADRGQHGMSKNQHGR
KADDLIVKVPPGTVVKDVKTGHILADLVTHGQSAVIAKGGRGGRGNSRFATPTNPAPEIAENGEPGQERDVILELKVLAD
VGLVGFPSVGKSTLLSVVSSARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKVGDEVKIFPISAVTKQGVRDL
LFEVANLLETTPEFPVHEVVDESEASVMYKFETEGVKFEITRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGM
GIDEALRARGAKDGDIVKILEYEFEFID

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI24308117, Length=334, Percent_Identity=40.7185628742515, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI111955139, Length=344, Percent_Identity=36.046511627907, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI111955063, Length=236, Percent_Identity=36.864406779661, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=38.135593220339, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI4557537, Length=90, Percent_Identity=44.4444444444444, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI58761500, Length=129, Percent_Identity=34.1085271317829, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1789574, Length=351, Percent_Identity=47.2934472934473, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI1787454, Length=138, Percent_Identity=35.5072463768116, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17508313, Length=321, Percent_Identity=38.6292834890966, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17552324, Length=308, Percent_Identity=30.8441558441558, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=31.6546762589928, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=36.4406779661017, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17555344, Length=118, Percent_Identity=35.5932203389831, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=194, Percent_Identity=37.1134020618557, Blast_Score=121, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=38.8888888888889, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321649, Length=141, Percent_Identity=29.7872340425532, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321612, Length=126, Percent_Identity=32.5396825396825, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI20129375, Length=304, Percent_Identity=40.1315789473684, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24585318, Length=309, Percent_Identity=39.1585760517799, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI17981711, Length=127, Percent_Identity=34.6456692913386, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21356473, Length=127, Percent_Identity=37.7952755905512, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47228; Mature: 47228

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDQVKIYVKAGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFQVDEGLRTLMDFRY
CCCCEEEEEEEECCCCCCEEEEEHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHH
QRHFKADRGQHGMSKNQHGRKADDLIVKVPPGTVVKDVKTGHILADLVTHGQSAVIAKGG
HHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCHHHHHHHHCCCCEEEEECC
RGGRGNSRFATPTNPAPEIAENGEPGQERDVILELKVLADVGLVGFPSVGKSTLLSVVSS
CCCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEEEEHHHCCCCCCCCCCHHHHHHHHHH
ARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
CCCCHHEEEEEEECCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKV
EEEEECCCCCCCCCCHHEEEECCCCEECCCEECCCCCEEEEECCCCCCHHHHHHHHHHHC
GDEVKIFPISAVTKQGVRDLLFEVANLLETTPEFPVHEVVDESEASVMYKFETEGVKFEI
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCEEEEE
TRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGMGIDEALRARGAKDGDIVKIL
EECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEE
EYEFEFID
EEEEEECC
>Mature Secondary Structure
MFVDQVKIYVKAGDGGNGMVAYRREKYVPKGGPAGGDGGKGADVVFQVDEGLRTLMDFRY
CCCCEEEEEEEECCCCCCEEEEEHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHH
QRHFKADRGQHGMSKNQHGRKADDLIVKVPPGTVVKDVKTGHILADLVTHGQSAVIAKGG
HHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCHHHHHHHHCCCCEEEEECC
RGGRGNSRFATPTNPAPEIAENGEPGQERDVILELKVLADVGLVGFPSVGKSTLLSVVSS
CCCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEEEEHHHCCCCCCCCCCHHHHHHHHHH
ARPKIAEYHFTTIVPNLGVVETGDNRSFVMADLPGLIEGAHAGVGLGHQFLRHIERTRVI
CCCCHHEEEEEEECCCCCEEEECCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHEEE
VHVIDMSGLEGRDPYEDYVTINNELKEYNLRLTERPQVVVANKMDMPDAEENLQAFKEKV
EEEEECCCCCCCCCCHHEEEECCCCEECCCEECCCCCEEEEECCCCCCHHHHHHHHHHHC
GDEVKIFPISAVTKQGVRDLLFEVANLLETTPEFPVHEVVDESEASVMYKFETEGVKFEI
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCEEEEEEECCCEEEEE
TRESDGTFVISGYDIEKTFKMTDFSRDESVRRFARQMRGMGIDEALRARGAKDGDIVKIL
EECCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEEEEE
EYEFEFID
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA