Click here to switch to the map view.

The map label for this gene is pheA [H]

Identifier: 152976850

GI number: 152976850

Start: 3198203

End: 3199054

Strand: Reverse

Name: pheA [H]

Synonym: Bcer98_3149

Alternate gene names: 152976850

Gene position: 3199054-3198203 (Counterclockwise)

Preceding gene: 152976851

Following gene: 152976846

Centisome position: 78.27

GC content: 37.79

Gene sequence:

>852_bases
ATGATTCGAGTAGGATATTTAGGACCAGAAGCAACATTTACAAATATGGCGGTGAGTCGTTTTTTTCCAGAAGCAGAGCA
TATACCATATAGAACAATTCCAGATTGTATGGATGCAGCAGCAAATGAAAATGTAGATTGCGCTGTTGTGCCACTAGAAA
ACGCGATAGAAGGTTCTGTTAATATTACCATTGACTATCTTGTACATGAGCAGCCGCTCTTTATTGTAGGAGAAATTACC
GTACCGATTCAGCAACATTTACTTGTGCATCCAAATTATGAAGAAACATGGAAAGATGTATATGCTGTATGCTCCCATCC
ACATGCTATTGCACAATGTCATAAATTTTTAAATGAAAAATTAAAAGGAATAACAGTTCGAGATATGACTTCTACGAGTG
CAGCGGCGCAATATGTGAAAGAACACCCAGAAGAAAAAATCGCAGCTATTGCAAATGAAGCAGCTGCTGAAAAATATGGA
TTAACAATTGTGCGGCACAATATACATACGCATAAAAATAATCATACTCGCTTTATTGTGTTGCATAAGAAAAAGAAGGC
ATCACTTCCAAGCAACGGAGAACATCGCGGAAAAAAAACGACCCTTATGATAACGTTACCTGCTGATTATGCAGGAGCAC
TGTATCAAGTTTTATCAGCCTTTGCATGGAGGAATTTAAACCTATCTAAAATTGAATCTCGTCCAATGAAAACAGGGCTT
GGAAATTACTTTTTCTTAATCGATGTAGATCGAGCATATGATGACGTATTATTGCCAAGTGTAACAATGGAGCTGGAAGC
GCTTGGATTTTCAGTCACGGTGTTAGGGAGCTATTCTTCTTATTGGTTGTAA

Upstream 100 bases:

>100_bases
CTAGCGAATGCTAGTCTTTTTTAAATATTCAAAATTTACATAGAAGAATATAAAAAAGTATGGTATAACAGTAAGAAAAC
GAAAAAGAGGGGAAAAGACG

Downstream 100 bases:

>100_bases
GAGGTGAGGGATGGACTGTCGATATTTGTCGGTAAATCGATATTTCCCTTCTAATCGCTGATATATTTTGAAAATCGCCG
ATATAACTTCATTGGATCAT

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MIRVGYLGPEATFTNMAVSRFFPEAEHIPYRTIPDCMDAAANENVDCAVVPLENAIEGSVNITIDYLVHEQPLFIVGEIT
VPIQQHLLVHPNYEETWKDVYAVCSHPHAIAQCHKFLNEKLKGITVRDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYG
LTIVRHNIHTHKNNHTRFIVLHKKKKASLPSNGEHRGKKTTLMITLPADYAGALYQVLSAFAWRNLNLSKIESRPMKTGL
GNYFFLIDVDRAYDDVLLPSVTMELEALGFSVTVLGSYSSYWL

Sequences:

>Translated_283_residues
MIRVGYLGPEATFTNMAVSRFFPEAEHIPYRTIPDCMDAAANENVDCAVVPLENAIEGSVNITIDYLVHEQPLFIVGEIT
VPIQQHLLVHPNYEETWKDVYAVCSHPHAIAQCHKFLNEKLKGITVRDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYG
LTIVRHNIHTHKNNHTRFIVLHKKKKASLPSNGEHRGKKTTLMITLPADYAGALYQVLSAFAWRNLNLSKIESRPMKTGL
GNYFFLIDVDRAYDDVLLPSVTMELEALGFSVTVLGSYSSYWL
>Mature_283_residues
MIRVGYLGPEATFTNMAVSRFFPEAEHIPYRTIPDCMDAAANENVDCAVVPLENAIEGSVNITIDYLVHEQPLFIVGEIT
VPIQQHLLVHPNYEETWKDVYAVCSHPHAIAQCHKFLNEKLKGITVRDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYG
LTIVRHNIHTHKNNHTRFIVLHKKKKASLPSNGEHRGKKTTLMITLPADYAGALYQVLSAFAWRNLNLSKIESRPMKTGL
GNYFFLIDVDRAYDDVLLPSVTMELEALGFSVTVLGSYSSYWL

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=282, Percent_Identity=30.4964539007092, Blast_Score=116, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324013, Length=284, Percent_Identity=28.169014084507, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 31740; Mature: 31740

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVGYLGPEATFTNMAVSRFFPEAEHIPYRTIPDCMDAAANENVDCAVVPLENAIEGSV
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCE
NITIDYLVHEQPLFIVGEITVPIQQHLLVHPNYEETWKDVYAVCSHPHAIAQCHKFLNEK
EEEEEEEEECCCEEEEEEEEECCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LKGITVRDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYGLTIVRHNIHTHKNNHTRFIV
HCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEEEE
LHKKKKASLPSNGEHRGKKTTLMITLPADYAGALYQVLSAFAWRNLNLSKIESRPMKTGL
EEECCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCC
GNYFFLIDVDRAYDDVLLPSVTMELEALGFSVTVLGSYSSYWL
CCEEEEEEECCCCCCCCCCHHHEEEECCCEEEEEEECCCCCCC
>Mature Secondary Structure
MIRVGYLGPEATFTNMAVSRFFPEAEHIPYRTIPDCMDAAANENVDCAVVPLENAIEGSV
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCE
NITIDYLVHEQPLFIVGEITVPIQQHLLVHPNYEETWKDVYAVCSHPHAIAQCHKFLNEK
EEEEEEEEECCCEEEEEEEEECCCCCEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LKGITVRDMTSTSAAAQYVKEHPEEKIAAIANEAAAEKYGLTIVRHNIHTHKNNHTRFIV
HCCCEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCEEEEE
LHKKKKASLPSNGEHRGKKTTLMITLPADYAGALYQVLSAFAWRNLNLSKIESRPMKTGL
EEECCCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCC
GNYFFLIDVDRAYDDVLLPSVTMELEALGFSVTVLGSYSSYWL
CCEEEEEEECCCCCCCCCCHHHEEEECCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2537815; 9384377; 8444804 [H]