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The map label for this gene is mtnN [H]

Identifier: 152976788

GI number: 152976788

Start: 3128903

End: 3129598

Strand: Reverse

Name: mtnN [H]

Synonym: Bcer98_3086

Alternate gene names: 152976788

Gene position: 3129598-3128903 (Counterclockwise)

Preceding gene: 152976789

Following gene: 152976787

Centisome position: 76.57

GC content: 37.07

Gene sequence:

>696_bases
TTGAGAATTGCTGTAATTGGAGCAATGGAAGAAGAAGTGCGTATTTTACGTGATAAATTAGAACAAGCAGAAATAGAAAG
CGTTGCTGGCTGTGAATTTACAAAAGGAATGTTAGTAGGACATGAAGTAATCTTGTTAAAATCCGGTATTGGTAAAGTGA
ACGCAGCGATGTCTACGACAATTTTGTTAGAAAGATATCAACCTGAAAAAGTAATCAATACAGGTTCAGCTGGTGGCTTC
CATCACGCTTTAAATGTTGGGGATGTTGTCATTTCAACTGAGGTTCGTCATCATGATGTGGATGTAACGGCATTTAATTA
TGAATACGGTCAAGTGCCAGGCATGCCACCAGGATTTAAAGCGGATAAAGAATTAGTTGCATTGGCAGAGCAATGCATGA
AGGAAGAAGAAAATATTCAAGTGGTTAAAGGAATGATTGCAACGGGTGACTCATTTATGAGTGATCCAAACCGAGTTGCA
GCAATTCGTGGTAAATTTGAAAATCTTTACGCAGTAGAAATGGAAGCAGCAGCTGTTGCACAAGTATGCCATCAATATAA
CGTTCCGTTTGTTATTATTCGTGCACTTTCTGATATTGCTGGTAAAGAATCAAATGTTTCATTTGACCAATTTTTAGATC
AAGCAGCTCTTCATTCTACAAACTTTATCGTAAAAGTATTGAAAGAGTTAAAGTAA

Upstream 100 bases:

>100_bases
AATCTATTTTTGAAAAGAATGGCTTCCATGTTACATTTACGAGACTAAATCATTTCGTTTGGGTTATGGAGGCAACTAAG
CAATAGAAAGAGGGATTAGA

Downstream 100 bases:

>100_bases
TGTAACAAAAAGGCAACTGTTTCATATAAAGAATTACATACAGTTGCCTTTTCTTTATTGGCAAGTAAGGAGGAGAACAC
GATGAAGGTGTATCGTGGGG

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MRIAVIGAMEEEVRILRDKLEQAEIESVAGCEFTKGMLVGHEVILLKSGIGKVNAAMSTTILLERYQPEKVINTGSAGGF
HHALNVGDVVISTEVRHHDVDVTAFNYEYGQVPGMPPGFKADKELVALAEQCMKEEENIQVVKGMIATGDSFMSDPNRVA
AIRGKFENLYAVEMEAAAVAQVCHQYNVPFVIIRALSDIAGKESNVSFDQFLDQAALHSTNFIVKVLKELK

Sequences:

>Translated_231_residues
MRIAVIGAMEEEVRILRDKLEQAEIESVAGCEFTKGMLVGHEVILLKSGIGKVNAAMSTTILLERYQPEKVINTGSAGGF
HHALNVGDVVISTEVRHHDVDVTAFNYEYGQVPGMPPGFKADKELVALAEQCMKEEENIQVVKGMIATGDSFMSDPNRVA
AIRGKFENLYAVEMEAAAVAQVCHQYNVPFVIIRALSDIAGKESNVSFDQFLDQAALHSTNFIVKVLKELK
>Mature_231_residues
MRIAVIGAMEEEVRILRDKLEQAEIESVAGCEFTKGMLVGHEVILLKSGIGKVNAAMSTTILLERYQPEKVINTGSAGGF
HHALNVGDVVISTEVRHHDVDVTAFNYEYGQVPGMPPGFKADKELVALAEQCMKEEENIQVVKGMIATGDSFMSDPNRVA
AIRGKFENLYAVEMEAAAVAQVCHQYNVPFVIIRALSDIAGKESNVSFDQFLDQAALHSTNFIVKVLKELK

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=230, Percent_Identity=53.4782608695652, Blast_Score=228, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 25309; Mature: 25309

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAVIGAMEEEVRILRDKLEQAEIESVAGCEFTKGMLVGHEVILLKSGIGKVNAAMSTT
CEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEEEEECCCCHHHHHHHHH
ILLERYQPEKVINTGSAGGFHHALNVGDVVISTEVRHHDVDVTAFNYEYGQVPGMPPGFK
HHHHHCCCHHHHCCCCCCCCHHHCCCCCEEEEECCEECCCEEEEEECCCCCCCCCCCCCC
ADKELVALAEQCMKEEENIQVVKGMIATGDSFMSDPNRVAAIRGKFENLYAVEMEAAAVA
CCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCCCEEHHHCCCCCEEEEHHHHHHHH
QVCHQYNVPFVIIRALSDIAGKESNVSFDQFLDQAALHSTNFIVKVLKELK
HHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRIAVIGAMEEEVRILRDKLEQAEIESVAGCEFTKGMLVGHEVILLKSGIGKVNAAMSTT
CEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCEEEEEECCCCHHHHHHHHH
ILLERYQPEKVINTGSAGGFHHALNVGDVVISTEVRHHDVDVTAFNYEYGQVPGMPPGFK
HHHHHCCCHHHHCCCCCCCCHHHCCCCCEEEEECCEECCCEEEEEECCCCCCCCCCCCCC
ADKELVALAEQCMKEEENIQVVKGMIATGDSFMSDPNRVAAIRGKFENLYAVEMEAAAVA
CCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHCCCCCEEHHHCCCCCEEEEHHHHHHHH
QVCHQYNVPFVIIRALSDIAGKESNVSFDQFLDQAALHSTNFIVKVLKELK
HHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA