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The map label for this gene is map [H]

Identifier: 152973978

GI number: 152973978

Start: 138456

End: 139202

Strand: Direct

Name: map [H]

Synonym: Bcer98_0126

Alternate gene names: 152973978

Gene position: 138456-139202 (Clockwise)

Preceding gene: 152973977

Following gene: 152973979

Centisome position: 3.39

GC content: 42.44

Gene sequence:

>747_bases
ATGATCATTTGCAAAACTCCTCGCGAGATAGAAATCATGCGAGAGGCTGGCAAGGTCGTTGCTTTAACTCATCAAGAGTT
GAAAAAGCATATTGCTCCAGGAATTACAACGAAAGAGCTCGATCAAATAGCGGAAAAGACGATTCGAAAATATGGTGCTA
CGCCATCTTTTAAAGGATACAACGGATTTCCGGGAAGCATATGTGCTTCTGTAAATGAAGAGCTTGTACACGGGATTCCA
GGAAAGCGCAAGCTCCAAGAAGGCGATATCATCAGTATCGATATTGGTGCGAAATACAATGGATATCATGGAGATTCTGC
ATGGACGTATCCAGTAGGAAACATTTCTGAATCTGTTCAAAAGCTACTTGATGTCACAGAAAAATCGTTGTATCTTGGTT
TAGAACAAGTAAAACCAGGCGAAAGATTATCTAACGTCTCACATGCGATTCAAACGTATGTTGAAGAGAATGGGTTGTCG
ATCGTTCGGGAGTATGTTGGTCACGGAATCGGGCAAGACTTACATGAGGATCCGCAAATTCCGCACTATGGTCCACCAAA
TCAAGGCCCTAGATTAAAGCCGGGAATGGTCATCTGTATTGAACCGATGGTGAACCAAGGAAGACGATATGTAAAAACAC
TATCTGATGACTGGACAGTGGTAACGGTAGATGGTAAATGGTGTGCCCATTTTGAGCACACGATTGCTCTTACAGAAGCA
GGATACGAAATCCTTACCACTTTATAA

Upstream 100 bases:

>100_bases
ATTTCTACGAGGAGCTGGGTTACTTACAAAGCATTAATGGTGAGCAAGATATCAATAAAGTATTTGCTGATATCGATGTT
CTCATCGGAGGCTTAGCGTA

Downstream 100 bases:

>100_bases
GTAGCTGGCTCTCCGGGATTTCAGAACAGTGTAAAATGTTACTGATTTGAAGAAGGGAGAACTATTGAATGGCGAAAGAT
GATGTAATTGAAGTCGAAGG

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP 1; Peptidase M [H]

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MIICKTPREIEIMREAGKVVALTHQELKKHIAPGITTKELDQIAEKTIRKYGATPSFKGYNGFPGSICASVNEELVHGIP
GKRKLQEGDIISIDIGAKYNGYHGDSAWTYPVGNISESVQKLLDVTEKSLYLGLEQVKPGERLSNVSHAIQTYVEENGLS
IVREYVGHGIGQDLHEDPQIPHYGPPNQGPRLKPGMVICIEPMVNQGRRYVKTLSDDWTVVTVDGKWCAHFEHTIALTEA
GYEILTTL

Sequences:

>Translated_248_residues
MIICKTPREIEIMREAGKVVALTHQELKKHIAPGITTKELDQIAEKTIRKYGATPSFKGYNGFPGSICASVNEELVHGIP
GKRKLQEGDIISIDIGAKYNGYHGDSAWTYPVGNISESVQKLLDVTEKSLYLGLEQVKPGERLSNVSHAIQTYVEENGLS
IVREYVGHGIGQDLHEDPQIPHYGPPNQGPRLKPGMVICIEPMVNQGRRYVKTLSDDWTVVTVDGKWCAHFEHTIALTEA
GYEILTTL
>Mature_248_residues
MIICKTPREIEIMREAGKVVALTHQELKKHIAPGITTKELDQIAEKTIRKYGATPSFKGYNGFPGSICASVNEELVHGIP
GKRKLQEGDIISIDIGAKYNGYHGDSAWTYPVGNISESVQKLLDVTEKSLYLGLEQVKPGERLSNVSHAIQTYVEENGLS
IVREYVGHGIGQDLHEDPQIPHYGPPNQGPRLKPGMVICIEPMVNQGRRYVKTLSDDWTVVTVDGKWCAHFEHTIALTEA
GYEILTTL

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=238, Percent_Identity=41.1764705882353, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI40385867, Length=214, Percent_Identity=41.1214953271028, Blast_Score=178, Evalue=4e-45,
Organism=Escherichia coli, GI1786364, Length=244, Percent_Identity=44.2622950819672, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1789275, Length=223, Percent_Identity=26.457399103139, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788728, Length=204, Percent_Identity=25.9803921568627, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71996291, Length=242, Percent_Identity=39.2561983471074, Blast_Score=180, Evalue=5e-46,
Organism=Saccharomyces cerevisiae, GI6323273, Length=218, Percent_Identity=45.8715596330275, Blast_Score=196, Evalue=4e-51,
Organism=Drosophila melanogaster, GI21355531, Length=238, Percent_Identity=42.8571428571429, Blast_Score=198, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24583427, Length=243, Percent_Identity=39.5061728395062, Blast_Score=181, Evalue=4e-46,
Organism=Drosophila melanogaster, GI19920384, Length=238, Percent_Identity=22.2689075630252, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 27489; Mature: 27489

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIICKTPREIEIMREAGKVVALTHQELKKHIAPGITTKELDQIAEKTIRKYGATPSFKGY
CEEECCCHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
NGFPGSICASVNEELVHGIPGKRKLQEGDIISIDIGAKYNGYHGDSAWTYPVGNISESVQ
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCCHHHHHH
KLLDVTEKSLYLGLEQVKPGERLSNVSHAIQTYVEENGLSIVREYVGHGIGQDLHEDPQI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHCCCCC
PHYGPPNQGPRLKPGMVICIEPMVNQGRRYVKTLSDDWTVVTVDGKWCAHFEHTIALTEA
CCCCCCCCCCCCCCCEEEEECCHHHCCHHHHHHCCCCEEEEEECCCEEECHHHEEEEHHC
GYEILTTL
CHHHHHCC
>Mature Secondary Structure
MIICKTPREIEIMREAGKVVALTHQELKKHIAPGITTKELDQIAEKTIRKYGATPSFKGY
CEEECCCHHHHHHHHCCCEEEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
NGFPGSICASVNEELVHGIPGKRKLQEGDIISIDIGAKYNGYHGDSAWTYPVGNISESVQ
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEECCCCCHHHHHH
KLLDVTEKSLYLGLEQVKPGERLSNVSHAIQTYVEENGLSIVREYVGHGIGQDLHEDPQI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHCCCCC
PHYGPPNQGPRLKPGMVICIEPMVNQGRRYVKTLSDDWTVVTVDGKWCAHFEHTIALTEA
CCCCCCCCCCCCCCCEEEEECCHHHCCHHHHHHCCCCEEEEEECCCEEECHHHEEEEHHC
GYEILTTL
CHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2113521; 8635744; 9384377 [H]