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The map label for this gene is resE [H]

Identifier: 152969449

GI number: 152969449

Start: 997024

End: 998496

Strand: Direct

Name: resE [H]

Synonym: KPN_00892

Alternate gene names: 152969449

Gene position: 997024-998496 (Clockwise)

Preceding gene: 152969448

Following gene: 152969456

Centisome position: 18.76

GC content: 63.34

Gene sequence:

>1473_bases
GTGATCCGCCGCCTGAGCCTCAGCCAGCGGCTGGCGCTGGTGGTGGTTTCCCTGCTGATGCTATGCGCGGTGGCGGTATG
CGCCGTCCAGTTACACAGCAGCGCGCAGTATGGCAACGCCATGGTGCAGCGTCTGTCGTCCGGGCTGGCTCAACAGATTG
TCGCCCGCGAGCCGTTGCTGGACGCCCACGGCGAGGTCAACCGGCAAACCCTGAAGTCGCTGTTTGACCGACTGATGACC
TTTAATCCCAGCGTGGAGCTCTATCTGCTGTCGCCGGATGGCGACCTGCTGGCCGATGCGGCGCCGCCGGGCCATATCCA
GCGCCAGCGTATCGACATGGCGCCGGTGCAGGCTTTTCTCACCGGCAGTGCGTCGCCGGTGTATGGCGACGATCCGCGCA
GTCCCGACGGACGAAAAGTCTTCAGCGCCGCCCCGCTGCGCGTCGACGGCCAACTGCGCGGCTACCTGTATATCATTTTG
CAGGGGGAGACGTTTAATCAGCTGGCGGCCGACGCCTGGCAAAAAACGCTGTGGAGCATTGTTCTGTGGACGCTGCTGCT
GGTGGCCCTGTTTGGCCTGCTGGCAGGGGGGCTGGCATGGTTCTGGGTCACCCGGCCGGTCCGCCTGCTCACCGCCCAGG
TGGCGGCGAGCGGCCAGGACAGCATCAGCGCCATCAAAACCCTGGCGGCCCGCAGGCCGGAGCCCCGGCCTGGTAACGAG
GTGGCGGTGCTCGAGAACCGCTTTATTGACCTTGCCCGGCAGATTGCCGATCAGTGGGATCGGCTGGCCGACAGCGATCG
CCAGCGCCGTGAATTTGTGGCCAATATCTCTCACGATTTGCGCACGCCGCTGACTTCGCTGCTGGGGTATCTGGAAACGC
TGACCCTGAAGGATGAATGGCTGACCGCCGAGGAGCGCAGGCAGTATCTCACCATCGCCCTGCGCCAGGGCAACAAAGTG
CGCCATCTCTCGCAGCAGCTGTTTGAGCTGGCGCGACTGGAGCATGGAGGCATTAAGCCGCAGCGCGAGCGTTTCGCGAT
GGGGGAGCTGATTTCCGACGTGGCGCAGAAGTTTGAATTAACTGCCCGCACGCGCGAGGTGAACCTGCATATTGATGTAC
CGGGACCGCTGCCGCTGATTAACGCCGATGTGTCGATGATTGAGAGGGTGGTGACCAATCTGCTCGATAACGCGATGCGG
CATACTCCCGTCGGCGGGGAGATCCGTCTGGCGGTCTGGCAGGAGAATCAACAGCTTCAGGTCGAAGTGGCAGACAACGG
AGCGGGCGTCGATGCCGCGCTGCGCGACGATCTGTTCCAGCGGCCGTCGGCGTTGTCTACCCAGGCATCGCGGGAGGATC
GCGGTGGGTTAGGGTTGCTGATTGTGAAACGAATGCTGGAGCTGCACGGGGGCGATATCAGACTGGTGGAGTCGGTAAGC
GGGGCGCGGTTCAGGTTCTTCGTGCCACTTTGA

Upstream 100 bases:

>100_bases
TGCGCAGTAAAATCGAACGTGACCCGGCCGAGCCGGACATCATTCTTACCGTCTGGGGAAAAGGCTATAAGTTCGCCCCG
GTGACGCAAGAGGCCGCCCC

Downstream 100 bases:

>100_bases
GAAATCGCCGGGTGGCGGCTACGCCTTACCCGGCCAACGTGGAAGAGCGGTGGCCGGGTAAGCGCAGCGCTACCCGGCGA
AAAAAGTTACTCCGGGAACC

Product: putative signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MIRRLSLSQRLALVVVSLLMLCAVAVCAVQLHSSAQYGNAMVQRLSSGLAQQIVAREPLLDAHGEVNRQTLKSLFDRLMT
FNPSVELYLLSPDGDLLADAAPPGHIQRQRIDMAPVQAFLTGSASPVYGDDPRSPDGRKVFSAAPLRVDGQLRGYLYIIL
QGETFNQLAADAWQKTLWSIVLWTLLLVALFGLLAGGLAWFWVTRPVRLLTAQVAASGQDSISAIKTLAARRPEPRPGNE
VAVLENRFIDLARQIADQWDRLADSDRQRREFVANISHDLRTPLTSLLGYLETLTLKDEWLTAEERRQYLTIALRQGNKV
RHLSQQLFELARLEHGGIKPQRERFAMGELISDVAQKFELTARTREVNLHIDVPGPLPLINADVSMIERVVTNLLDNAMR
HTPVGGEIRLAVWQENQQLQVEVADNGAGVDAALRDDLFQRPSALSTQASREDRGGLGLLIVKRMLELHGGDIRLVESVS
GARFRFFVPL

Sequences:

>Translated_490_residues
MIRRLSLSQRLALVVVSLLMLCAVAVCAVQLHSSAQYGNAMVQRLSSGLAQQIVAREPLLDAHGEVNRQTLKSLFDRLMT
FNPSVELYLLSPDGDLLADAAPPGHIQRQRIDMAPVQAFLTGSASPVYGDDPRSPDGRKVFSAAPLRVDGQLRGYLYIIL
QGETFNQLAADAWQKTLWSIVLWTLLLVALFGLLAGGLAWFWVTRPVRLLTAQVAASGQDSISAIKTLAARRPEPRPGNE
VAVLENRFIDLARQIADQWDRLADSDRQRREFVANISHDLRTPLTSLLGYLETLTLKDEWLTAEERRQYLTIALRQGNKV
RHLSQQLFELARLEHGGIKPQRERFAMGELISDVAQKFELTARTREVNLHIDVPGPLPLINADVSMIERVVTNLLDNAMR
HTPVGGEIRLAVWQENQQLQVEVADNGAGVDAALRDDLFQRPSALSTQASREDRGGLGLLIVKRMLELHGGDIRLVESVS
GARFRFFVPL
>Mature_490_residues
MIRRLSLSQRLALVVVSLLMLCAVAVCAVQLHSSAQYGNAMVQRLSSGLAQQIVAREPLLDAHGEVNRQTLKSLFDRLMT
FNPSVELYLLSPDGDLLADAAPPGHIQRQRIDMAPVQAFLTGSASPVYGDDPRSPDGRKVFSAAPLRVDGQLRGYLYIIL
QGETFNQLAADAWQKTLWSIVLWTLLLVALFGLLAGGLAWFWVTRPVRLLTAQVAASGQDSISAIKTLAARRPEPRPGNE
VAVLENRFIDLARQIADQWDRLADSDRQRREFVANISHDLRTPLTSLLGYLETLTLKDEWLTAEERRQYLTIALRQGNKV
RHLSQQLFELARLEHGGIKPQRERFAMGELISDVAQKFELTARTREVNLHIDVPGPLPLINADVSMIERVVTNLLDNAMR
HTPVGGEIRLAVWQENQQLQVEVADNGAGVDAALRDDLFQRPSALSTQASREDRGGLGLLIVKRMLELHGGDIRLVESVS
GARFRFFVPL

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=236, Percent_Identity=33.0508474576271, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788549, Length=234, Percent_Identity=27.7777777777778, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788713, Length=248, Percent_Identity=25.4032258064516, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789149, Length=255, Percent_Identity=28.2352941176471, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=28.2511210762332, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1786783, Length=344, Percent_Identity=25.5813953488372, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788393, Length=254, Percent_Identity=27.1653543307087, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=25.531914893617, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790861, Length=352, Percent_Identity=24.7159090909091, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790436, Length=221, Percent_Identity=24.4343891402715, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48994928, Length=240, Percent_Identity=25.4166666666667, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788279, Length=205, Percent_Identity=26.3414634146341, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=228, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790300, Length=240, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54525; Mature: 54525

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRLSLSQRLALVVVSLLMLCAVAVCAVQLHSSAQYGNAMVQRLSSGLAQQIVAREPLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
DAHGEVNRQTLKSLFDRLMTFNPSVELYLLSPDGDLLADAAPPGHIQRQRIDMAPVQAFL
CCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCHHHHHCCHHHHHHHH
TGSASPVYGDDPRSPDGRKVFSAAPLRVDGQLRGYLYIILQGETFNQLAADAWQKTLWSI
CCCCCCCCCCCCCCCCCCEEEECCCEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
VLWTLLLVALFGLLAGGLAWFWVTRPVRLLTAQVAASGQDSISAIKTLAARRPEPRPGNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCE
VAVLENRFIDLARQIADQWDRLADSDRQRREFVANISHDLRTPLTSLLGYLETLTLKDEW
EEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LTAEERRQYLTIALRQGNKVRHLSQQLFELARLEHGGIKPQRERFAMGELISDVAQKFEL
CCHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
TARTREVNLHIDVPGPLPLINADVSMIERVVTNLLDNAMRHTPVGGEIRLAVWQENQQLQ
HEEEEEEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEE
VEVADNGAGVDAALRDDLFQRPSALSTQASREDRGGLGLLIVKRMLELHGGDIRLVESVS
EEECCCCCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCC
GARFRFFVPL
CCEEEEEECC
>Mature Secondary Structure
MIRRLSLSQRLALVVVSLLMLCAVAVCAVQLHSSAQYGNAMVQRLSSGLAQQIVAREPLL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
DAHGEVNRQTLKSLFDRLMTFNPSVELYLLSPDGDLLADAAPPGHIQRQRIDMAPVQAFL
CCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCCHHHHHCCHHHHHHHH
TGSASPVYGDDPRSPDGRKVFSAAPLRVDGQLRGYLYIILQGETFNQLAADAWQKTLWSI
CCCCCCCCCCCCCCCCCCEEEECCCEEECCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
VLWTLLLVALFGLLAGGLAWFWVTRPVRLLTAQVAASGQDSISAIKTLAARRPEPRPGNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCE
VAVLENRFIDLARQIADQWDRLADSDRQRREFVANISHDLRTPLTSLLGYLETLTLKDEW
EEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
LTAEERRQYLTIALRQGNKVRHLSQQLFELARLEHGGIKPQRERFAMGELISDVAQKFEL
CCHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
TARTREVNLHIDVPGPLPLINADVSMIERVVTNLLDNAMRHTPVGGEIRLAVWQENQQLQ
HEEEEEEEEEEECCCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEE
VEVADNGAGVDAALRDDLFQRPSALSTQASREDRGGLGLLIVKRMLELHGGDIRLVESVS
EEECCCCCCCCHHHHHHHHHCCCHHCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCC
GARFRFFVPL
CCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]