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The map label for this gene is ybiN [H]

Identifier: 152969393

GI number: 152969393

Start: 931359

End: 932273

Strand: Direct

Name: ybiN [H]

Synonym: KPN_00836

Alternate gene names: 152969393

Gene position: 931359-932273 (Clockwise)

Preceding gene: 152969389

Following gene: 152969400

Centisome position: 17.52

GC content: 60.44

Gene sequence:

>915_bases
ATGAAAGCCCAGAAACCGGGGTTACACCCGCGTAACCGCCACCATCAACGCTACGACCTGCCCGCGCTCTGCCAGGCCCA
TCCTGACCTGCAGGGCTACATTACGCTCAATCCGCTGGGTGAGCAGACCATTGATTTTGCCAATCCGCAGGCGGTGAAGG
CGTTGAATAAAGCGCTGCTGGCGCATTTCTACGCGGTCAAACACTGGGACATTCCTGACGGCTTTCTCTGTCCGCCAGTG
CCTGGGCGGGCCGACTATATTCATCATCTGGCGGATCTGCTGGCCGGGGATAGCGGCGAGGTGCCGAAGGATGCCACGAT
CCTTGATATTGGCACCGGCGCGAACCTCATCTATCCCCTGATCGGCGCTCACGAGTATGGCTGGCGCTTTACCGGCAGTG
AAATCAACCCGCAGGCGTTCGCCAGCGCGCAGGCGATTATCAATGGCAACCCGGGCTTGACCCGGCAGATCCGCCTGCGC
CGGCAAAAAGAGAGCCAGGCTATCTTTCACGGCGTGATCCATAAAAACGAGACCTACGACGCCACGCTGTGTAATCCGCC
GTTCCATGACTCCGCAGAGAGCGCCCGGGCGGGGGGCGAGCGCAAGCGCCGCAACCTCGGACTCGGCGCCGAAAGTGGCC
TCAATTTTGGCGGTCAGCAGCAGGAGCTGTGGTGCGAAGGGGGCGAAGTAGCCTTTATCTCGCAGATGATCCGCGAAAGC
CAGGCCTTCGCCCGCCAGGTGAAATGGTTTACCTCGCTGGTGTCGCGCGGCGATAATCTGCCGCCGCTCTACCGCCTGCT
GACCGAGGTCGGCGCAGTGAAAGTGGTGAAAAAGGAGATGGCCCAGGGGCAAAAGCAAAGTCGCTTTATCGCCTGGAGCT
TTATGGACGACGCCAAACGCCGTCGTCCATTCTAA

Upstream 100 bases:

>100_bases
ACATGCTGCACCTGTCACGGATAATGGAGATATCCAGACTCCCTTATTTACCGCGCCGCCGTCAACGGGTATCTTACGCG
GCTGTTCAAAGGAGATTGTC

Downstream 100 bases:

>100_bases
CGCTACTCGGCGGCCGGGCTGTCGGCGCCCGGCATCGGCAGCTGCTGCCAGGTCTGTACCGGCGCGCGAACCCCGGCGCG
GTCGAAGTGCTTTTTCACCT

Product: putative SAM-dependent methyltransferase

Products: NA

Alternate protein names: 23S rRNA mA1618 methyltransferase; rRNA adenine N-6-methyltransferase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKAQKPGLHPRNRHHQRYDLPALCQAHPDLQGYITLNPLGEQTIDFANPQAVKALNKALLAHFYAVKHWDIPDGFLCPPV
PGRADYIHHLADLLAGDSGEVPKDATILDIGTGANLIYPLIGAHEYGWRFTGSEINPQAFASAQAIINGNPGLTRQIRLR
RQKESQAIFHGVIHKNETYDATLCNPPFHDSAESARAGGERKRRNLGLGAESGLNFGGQQQELWCEGGEVAFISQMIRES
QAFARQVKWFTSLVSRGDNLPPLYRLLTEVGAVKVVKKEMAQGQKQSRFIAWSFMDDAKRRRPF

Sequences:

>Translated_304_residues
MKAQKPGLHPRNRHHQRYDLPALCQAHPDLQGYITLNPLGEQTIDFANPQAVKALNKALLAHFYAVKHWDIPDGFLCPPV
PGRADYIHHLADLLAGDSGEVPKDATILDIGTGANLIYPLIGAHEYGWRFTGSEINPQAFASAQAIINGNPGLTRQIRLR
RQKESQAIFHGVIHKNETYDATLCNPPFHDSAESARAGGERKRRNLGLGAESGLNFGGQQQELWCEGGEVAFISQMIRES
QAFARQVKWFTSLVSRGDNLPPLYRLLTEVGAVKVVKKEMAQGQKQSRFIAWSFMDDAKRRRPF
>Mature_304_residues
MKAQKPGLHPRNRHHQRYDLPALCQAHPDLQGYITLNPLGEQTIDFANPQAVKALNKALLAHFYAVKHWDIPDGFLCPPV
PGRADYIHHLADLLAGDSGEVPKDATILDIGTGANLIYPLIGAHEYGWRFTGSEINPQAFASAQAIINGNPGLTRQIRLR
RQKESQAIFHGVIHKNETYDATLCNPPFHDSAESARAGGERKRRNLGLGAESGLNFGGQQQELWCEGGEVAFISQMIRES
QAFARQVKWFTSLVSRGDNLPPLYRLLTEVGAVKVVKKEMAQGQKQSRFIAWSFMDDAKRRRPF

Specific function: Specifically methylates the adenine in position 1618 of 23S rRNA [H]

COG id: COG3129

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. METT10D/rlmF family [H]

Homologues:

Organism=Homo sapiens, GI122114654, Length=305, Percent_Identity=31.1475409836066, Blast_Score=154, Evalue=8e-38,
Organism=Escherichia coli, GI87081786, Length=302, Percent_Identity=78.8079470198676, Blast_Score=513, Evalue=1e-147,
Organism=Caenorhabditis elegans, GI32564931, Length=308, Percent_Identity=26.9480519480519, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI32564933, Length=308, Percent_Identity=24.6753246753247, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI281363415, Length=294, Percent_Identity=29.5918367346939, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI19922302, Length=294, Percent_Identity=29.5918367346939, Blast_Score=121, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016909
- InterPro:   IPR010286 [H]

Pfam domain/function: PF05971 Methyltransf_10 [H]

EC number: =2.1.1.181 [H]

Molecular weight: Translated: 33895; Mature: 33895

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAQKPGLHPRNRHHQRYDLPALCQAHPDLQGYITLNPLGEQTIDFANPQAVKALNKALL
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCHHCCCCHHHHHHHHHHHH
AHFYAVKHWDIPDGFLCPPVPGRADYIHHLADLLAGDSGEVPKDATILDIGTGANLIYPL
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHH
IGAHEYGWRFTGSEINPQAFASAQAIINGNPGLTRQIRLRRQKESQAIFHGVIHKNETYD
HCCCCCCCEEECCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
ATLCNPPFHDSAESARAGGERKRRNLGLGAESGLNFGGQQQELWCEGGEVAFISQMIRES
EEECCCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHH
QAFARQVKWFTSLVSRGDNLPPLYRLLTEVGAVKVVKKEMAQGQKQSRFIAWSFMDDAKR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCEEEEEEHHHHHHH
RRPF
CCCC
>Mature Secondary Structure
MKAQKPGLHPRNRHHQRYDLPALCQAHPDLQGYITLNPLGEQTIDFANPQAVKALNKALL
CCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCEEEEECCCCCCHHCCCCHHHHHHHHHHHH
AHFYAVKHWDIPDGFLCPPVPGRADYIHHLADLLAGDSGEVPKDATILDIGTGANLIYPL
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHH
IGAHEYGWRFTGSEINPQAFASAQAIINGNPGLTRQIRLRRQKESQAIFHGVIHKNETYD
HCCCCCCCEEECCCCCHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
ATLCNPPFHDSAESARAGGERKRRNLGLGAESGLNFGGQQQELWCEGGEVAFISQMIRES
EEECCCCCCCCHHHHHCCCHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHH
QAFARQVKWFTSLVSRGDNLPPLYRLLTEVGAVKVVKKEMAQGQKQSRFIAWSFMDDAKR
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHCEEEEEEHHHHHHH
RRPF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA