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The map label for this gene is rsbU

Identifier: 151222185

GI number: 151222185

Start: 2191247

End: 2192248

Strand: Reverse

Name: rsbU

Synonym: NWMN_1973

Alternate gene names: 151222185

Gene position: 2192248-2191247 (Counterclockwise)

Preceding gene: 151222186

Following gene: 151222184

Centisome position: 76.15

GC content: 31.34

Gene sequence:

>1002_bases
GTGGAAGAATTTAAGCAACATTATAAGGGTTTAATTGATGAAAGTTTAACGTGCCAAGATAAAGTAGAATTGATAAAAAA
GTGTGAGAAATACACTGACGAAGTGATTCGTAAGGACGTCTTGCCTGAAGACATTGTCGATATTCACAAAAACTATATAT
TGACGTTAAACTTAACGCGTGAAGATGTGTTCAAGACATTAGATGTCTTACAAGAAATCGTTAAAGGCTTTGGTTATAGT
TATCGAGATTATCAAAGATTGGTAGATAAACTTCAAGTTCACGATAAAGAGATAGACTTAGCTTCTAGCTTACAACAAAC
AATGCTTAAAACAGATATTCCACAATTTGATAGTATTCAAATTGGCGTTATTTCAGTGGCGGCACAAAAAGTAAGTGGAG
ATTATTTTAATTTAATTGACCATAACGATGGCACAATGAGCTTTGCTGTTGCAGATGTCATTGGAAAAGGTATACCAGCT
GCTTTAGCAATGAGTATGATAAAGTTTGGCATGGATTCTTATGGACACTCACAATTACCGAGTGATGGTTTAAAACGTTT
AAATCGTGTTGTTGAAAAGAATATTAATCAAAATATGTTCGTCACAATGTTTTATGGTTTATATGAAGAAATGAACCATT
TATTGTATTGTAGTTCAGCTGGTCATGAGCCTGGATATATTTATCGCGCTGAAAAAGAAGAATTTGAAGAAATTTCAGTT
AGAGGTAGAGTGTTAGGAATCAGTTCACAAACACGATATCAACAACAAGAAATTCCAATATACCTTGATGATTTAATTAT
CATTTTAACGGATGGTGTGACTGAAGCTAGAAATAGTGAAGGTACCTTTATAGATAAACAAAAACTTTTAGAATATATTA
AAAAACATAAACATATGCACCCACAAGATATTGTTCAAATTATCTATGAAGCAATTTTAAAGCTTCAAAACCCAAATAAA
AAAGATGATATGACTATTTTGATTATAAAAAGAGTAAATTAA

Upstream 100 bases:

>100_bases
ACAAAATTGATAAGTGCAATTAAATAAATGTTAGTAAGTGAATCATAATTATCCTTGCTTAAGCATTTGCTTTGTAAGGG
AAGTGAGGAGGCAACTAATC

Downstream 100 bases:

>100_bases
TTTAAAAAAAGAAGATTAGAAATTATTTCGATGGGTATATAATAATTTGAAATATAAATATGGTGGATACAGCGCTTAAA
ATGAAGATAAATATTTTTAA

Product: sigma factor sigB regulation protein

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MEEFKQHYKGLIDESLTCQDKVELIKKCEKYTDEVIRKDVLPEDIVDIHKNYILTLNLTREDVFKTLDVLQEIVKGFGYS
YRDYQRLVDKLQVHDKEIDLASSLQQTMLKTDIPQFDSIQIGVISVAAQKVSGDYFNLIDHNDGTMSFAVADVIGKGIPA
ALAMSMIKFGMDSYGHSQLPSDGLKRLNRVVEKNINQNMFVTMFYGLYEEMNHLLYCSSAGHEPGYIYRAEKEEFEEISV
RGRVLGISSQTRYQQQEIPIYLDDLIIILTDGVTEARNSEGTFIDKQKLLEYIKKHKHMHPQDIVQIIYEAILKLQNPNK
KDDMTILIIKRVN

Sequences:

>Translated_333_residues
MEEFKQHYKGLIDESLTCQDKVELIKKCEKYTDEVIRKDVLPEDIVDIHKNYILTLNLTREDVFKTLDVLQEIVKGFGYS
YRDYQRLVDKLQVHDKEIDLASSLQQTMLKTDIPQFDSIQIGVISVAAQKVSGDYFNLIDHNDGTMSFAVADVIGKGIPA
ALAMSMIKFGMDSYGHSQLPSDGLKRLNRVVEKNINQNMFVTMFYGLYEEMNHLLYCSSAGHEPGYIYRAEKEEFEEISV
RGRVLGISSQTRYQQQEIPIYLDDLIIILTDGVTEARNSEGTFIDKQKLLEYIKKHKHMHPQDIVQIIYEAILKLQNPNK
KDDMTILIIKRVN
>Mature_333_residues
MEEFKQHYKGLIDESLTCQDKVELIKKCEKYTDEVIRKDVLPEDIVDIHKNYILTLNLTREDVFKTLDVLQEIVKGFGYS
YRDYQRLVDKLQVHDKEIDLASSLQQTMLKTDIPQFDSIQIGVISVAAQKVSGDYFNLIDHNDGTMSFAVADVIGKGIPA
ALAMSMIKFGMDSYGHSQLPSDGLKRLNRVVEKNINQNMFVTMFYGLYEEMNHLLYCSSAGHEPGYIYRAEKEEFEEISV
RGRVLGISSQTRYQQQEIPIYLDDLIIILTDGVTEARNSEGTFIDKQKLLEYIKKHKHMHPQDIVQIIYEAILKLQNPNK
KDDMTILIIKRVN

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 38427; Mature: 38427

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEFKQHYKGLIDESLTCQDKVELIKKCEKYTDEVIRKDVLPEDIVDIHKNYILTLNLTR
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCH
EDVFKTLDVLQEIVKGFGYSYRDYQRLVDKLQVHDKEIDLASSLQQTMLKTDIPQFDSIQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IGVISVAAQKVSGDYFNLIDHNDGTMSFAVADVIGKGIPAALAMSMIKFGMDSYGHSQLP
EHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
SDGLKRLNRVVEKNINQNMFVTMFYGLYEEMNHLLYCSSAGHEPGYIYRAEKEEFEEISV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCEEEECCHHHHHHHHH
RGRVLGISSQTRYQQQEIPIYLDDLIIILTDGVTEARNSEGTFIDKQKLLEYIKKHKHMH
CCEEEECCCHHHHHHHCCCEEECCEEEEEECCCHHCCCCCCCEECHHHHHHHHHHHCCCC
PQDIVQIIYEAILKLQNPNKKDDMTILIIKRVN
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MEEFKQHYKGLIDESLTCQDKVELIKKCEKYTDEVIRKDVLPEDIVDIHKNYILTLNLTR
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCEEEEEECCH
EDVFKTLDVLQEIVKGFGYSYRDYQRLVDKLQVHDKEIDLASSLQQTMLKTDIPQFDSIQ
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
IGVISVAAQKVSGDYFNLIDHNDGTMSFAVADVIGKGIPAALAMSMIKFGMDSYGHSQLP
EHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
SDGLKRLNRVVEKNINQNMFVTMFYGLYEEMNHLLYCSSAGHEPGYIYRAEKEEFEEISV
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEECCCCCCCCEEEECCHHHHHHHHH
RGRVLGISSQTRYQQQEIPIYLDDLIIILTDGVTEARNSEGTFIDKQKLLEYIKKHKHMH
CCEEEECCCHHHHHHHCCCEEECCEEEEEECCCHHCCCCCCCEECHHHHHHHHHHHCCCC
PQDIVQIIYEAILKLQNPNKKDDMTILIIKRVN
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]