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The map label for this gene is rsbW

Identifier: 151222183

GI number: 151222183

Start: 2190320

End: 2190799

Strand: Reverse

Name: rsbW

Synonym: NWMN_1971

Alternate gene names: 151222183

Gene position: 2190799-2190320 (Counterclockwise)

Preceding gene: 151222184

Following gene: 151222182

Centisome position: 76.1

GC content: 32.71

Gene sequence:

>480_bases
ATGCAATCTAAAGAAGATTTTATCGAAATGCGCGTGCCAGCATCGGCAGAGTATGTAAGTTTAATTCGTTTAACACTTTC
TGGCGTTTTTTCGAGAGCTGGTGCTACATATGATGATATTGAAGATGCCAAGATTGCAGTTAGTGAAGCTGTGACAAATG
CAGTTAAACATGCATACAAAGAAAATAACAATGTGGGCATTATTAACATATATTTTGAAATTTTAGAAGATAAAATTAAA
ATTGTTATTTCTGATAAAGGTGACAGTTTTGATTATGAAACAACTAAATCAAAAATAGGTCCTTACGATAAAGACGAAAA
TATAGACTTTTTACGCGAAGGTGGCCTAGGTTTATTTTTAATCGAATCTTTAATGGATGAAGTCACAGTATATAAAGAAT
CTGGTGTGACAATCAGTATGACTAAGTATATAAAAAAAGAGCAGGTGCGAAATAATGGCGAAAGAGTCGAAATCAGCTAA

Upstream 100 bases:

>100_bases
CTATACATTTTAGGTGTGTCAGATCGTATCGGTAGACTATTTGAAATTACTGGTCTTAAGGATTTAATGCATGTTAATGA
AGGAACGGAGGTCGAATAAC

Downstream 100 bases:

>100_bases
TGAAATTTCACCTGAGCAAATTAACCAATGGATTAAAGAACACCAAGAAAATAAGAATACAGATGCACAGGATAAGTTAG
TTAAACATTACCAAAAACTA

Product: serine-protein kinase RsbW

Products: NA

Alternate protein names: Anti-sigma-B factor; Sigma-B negative effector rsbW

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MQSKEDFIEMRVPASAEYVSLIRLTLSGVFSRAGATYDDIEDAKIAVSEAVTNAVKHAYKENNNVGIINIYFEILEDKIK
IVISDKGDSFDYETTKSKIGPYDKDENIDFLREGGLGLFLIESLMDEVTVYKESGVTISMTKYIKKEQVRNNGERVEIS

Sequences:

>Translated_159_residues
MQSKEDFIEMRVPASAEYVSLIRLTLSGVFSRAGATYDDIEDAKIAVSEAVTNAVKHAYKENNNVGIINIYFEILEDKIK
IVISDKGDSFDYETTKSKIGPYDKDENIDFLREGGLGLFLIESLMDEVTVYKESGVTISMTKYIKKEQVRNNGERVEIS
>Mature_159_residues
MQSKEDFIEMRVPASAEYVSLIRLTLSGVFSRAGATYDDIEDAKIAVSEAVTNAVKHAYKENNNVGIINIYFEILEDKIK
IVISDKGDSFDYETTKSKIGPYDKDENIDFLREGGLGLFLIESLMDEVTVYKESGVTISMTKYIKKEQVRNNGERVEIS

Specific function: Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, rsbV. Upon phosphorylation of rsbV, rsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B

COG id: COG2172

COG function: function code T; Anti-sigma regulatory factor (Ser/Thr protein kinase)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anti-sigma-factor family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSBW_STAA1 (A7X4P1)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442640.1
- ProteinModelPortal:   A7X4P1
- SMR:   A7X4P1
- STRING:   A7X4P1
- EnsemblBacteria:   EBSTAT00000004561
- GeneID:   5561273
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2050
- eggNOG:   COG2172
- GeneTree:   EBGT00050000025531
- HOGENOM:   HBG425195
- OMA:   GEITIVF
- ProtClustDB:   PRK04069
- BioCyc:   SAUR418127:SAHV_2050-MONOMER
- HAMAP:   MF_00638
- InterPro:   IPR010193
- InterPro:   IPR003594
- Gene3D:   G3DSA:3.30.565.10
- SMART:   SM00387
- TIGRFAMs:   TIGR01924

Pfam domain/function: PF02518 HATPase_c; SSF55874 ATP_bd_ATPase

EC number: =2.7.11.1

Molecular weight: Translated: 17921; Mature: 17921

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSKEDFIEMRVPASAEYVSLIRLTLSGVFSRAGATYDDIEDAKIAVSEAVTNAVKHAYK
CCCHHHHEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ENNNVGIINIYFEILEDKIKIVISDKGDSFDYETTKSKIGPYDKDENIDFLREGGLGLFL
CCCCEEEEEHHHHHHHCCEEEEEECCCCCCCCCCHHHHCCCCCCCCCCHHHHCCCCHHHH
IESLMDEVTVYKESGVTISMTKYIKKEQVRNNGERVEIS
HHHHHHHHHEECCCCCEEEHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MQSKEDFIEMRVPASAEYVSLIRLTLSGVFSRAGATYDDIEDAKIAVSEAVTNAVKHAYK
CCCHHHHEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ENNNVGIINIYFEILEDKIKIVISDKGDSFDYETTKSKIGPYDKDENIDFLREGGLGLFL
CCCCEEEEEHHHHHHHCCEEEEEECCCCCCCCCCHHHHCCCCCCCCCCHHHHCCCCHHHH
IESLMDEVTVYKESGVTISMTKYIKKEQVRNNGERVEIS
HHHHHHHHHEECCCCCEEEHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA