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The map label for this gene is asd [H]

Identifier: 150401791

GI number: 150401791

Start: 1432072

End: 1433121

Strand: Direct

Name: asd [H]

Synonym: Maeo_1369

Alternate gene names: 150401791

Gene position: 1432072-1433121 (Clockwise)

Preceding gene: 150401788

Following gene: 150401792

Centisome position: 91.24

GC content: 35.52

Gene sequence:

>1050_bases
ATGATAAAAGTAGGAGTTTTAGGAGCTACTGGAAATGTGGGACAAAGATTTATGCAAATGCTTGAAAACCACCCCATATT
TGAATTAGAAGTATTGGGAGCATCATCAAGGAGTGCAGGTAAAAAATATGCTGACGCTTGTTATTGGTATCAAACAGAGC
CAATTCCTGAAGAATATGCAAATAAAATGGTGCAAACAACCGACCCAACAGACAAAGCTTATGAGGATGTAGATATAGTA
TTTTCAGCATTACCTTCCGATTTAGCAAAAAAATTAGAACCAGAATTCGCAAAAGAGGGAAAATTAGTTTTCTCAAACGC
ATCAGCTATGAGAATGGAAAATGATGTTCCGTTAATGATTCCAGAAGTAAACTATGACCATTTCGAGATGCTGGACATAC
AAAGAGAAAATAGAAATTATGATGGTGCAATAATTACAAATCCAAATTGTTCGACAATATGTGCCGTAATTACGCTAAAA
CCAATTATGGATAAATTTGGTATTGATTTGGTTAATATTACCACAATGCAGGCAATAAGTGGGGCAGGGTATAATGGAGT
TCCATCTATGGCAATAATTGATAATCTTGTGCCTTACATCGGTAGTGAAGAGGAAAAGATGCAAACTGAAAGTTTAAAAC
TATTAGGGGCAATAGATAAAGAAAATAATAAATTTACAGACGCAAACTTTAAAATTGGAGTATCCTGTAATAGGGTTTCA
GTAATTGATGGGCATACGGAAAGTATATTCGTAAAAACAACAGAAGAAGCTACGCCAGAAGAAATTAAAAAAGTTATGGA
CAAATTCGACCCATTAAAAGAATACAACCTTCCAACCTATGCAAAACCTATTGTTATTAGGGAAGAGATGGACAGACCAC
AGCCAAGATTGGATAGGGATGCAGGAAATGGTATGAGTATAAGTGTAGGGAGAATTAGGGAAGATCCAGTATTTGGCATA
AAATATACGGCATTGGAACACAACACCATAAGGGGGGCTGCTGGTGCAAGTGTTTTAAATGCTGAGTTGTATGTTAAAAA
ATATCTTTAA

Upstream 100 bases:

>100_bases
GATTATTATAAATAATAGTATAAATAACATAATAGAATTAATAAAATTATAATATATAATATAATAAAATTATAATATAT
ATAATATACCCGGTGATAAA

Downstream 100 bases:

>100_bases
AATTATATTTAAAGCATAATTAAAGCATAATTAAAATATTATACAATAATTAAATAATATTAAAAAACCAAATAATTTAT
TTTTTCATATCTATTTTTTA

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MIKVGVLGATGNVGQRFMQMLENHPIFELEVLGASSRSAGKKYADACYWYQTEPIPEEYANKMVQTTDPTDKAYEDVDIV
FSALPSDLAKKLEPEFAKEGKLVFSNASAMRMENDVPLMIPEVNYDHFEMLDIQRENRNYDGAIITNPNCSTICAVITLK
PIMDKFGIDLVNITTMQAISGAGYNGVPSMAIIDNLVPYIGSEEEKMQTESLKLLGAIDKENNKFTDANFKIGVSCNRVS
VIDGHTESIFVKTTEEATPEEIKKVMDKFDPLKEYNLPTYAKPIVIREEMDRPQPRLDRDAGNGMSISVGRIREDPVFGI
KYTALEHNTIRGAAGASVLNAELYVKKYL

Sequences:

>Translated_349_residues
MIKVGVLGATGNVGQRFMQMLENHPIFELEVLGASSRSAGKKYADACYWYQTEPIPEEYANKMVQTTDPTDKAYEDVDIV
FSALPSDLAKKLEPEFAKEGKLVFSNASAMRMENDVPLMIPEVNYDHFEMLDIQRENRNYDGAIITNPNCSTICAVITLK
PIMDKFGIDLVNITTMQAISGAGYNGVPSMAIIDNLVPYIGSEEEKMQTESLKLLGAIDKENNKFTDANFKIGVSCNRVS
VIDGHTESIFVKTTEEATPEEIKKVMDKFDPLKEYNLPTYAKPIVIREEMDRPQPRLDRDAGNGMSISVGRIREDPVFGI
KYTALEHNTIRGAAGASVLNAELYVKKYL
>Mature_349_residues
MIKVGVLGATGNVGQRFMQMLENHPIFELEVLGASSRSAGKKYADACYWYQTEPIPEEYANKMVQTTDPTDKAYEDVDIV
FSALPSDLAKKLEPEFAKEGKLVFSNASAMRMENDVPLMIPEVNYDHFEMLDIQRENRNYDGAIITNPNCSTICAVITLK
PIMDKFGIDLVNITTMQAISGAGYNGVPSMAIIDNLVPYIGSEEEKMQTESLKLLGAIDKENNKFTDANFKIGVSCNRVS
VIDGHTESIFVKTTEEATPEEIKKVMDKFDPLKEYNLPTYAKPIVIREEMDRPQPRLDRDAGNGMSISVGRIREDPVFGI
KYTALEHNTIRGAAGASVLNAELYVKKYL

Specific function: This enzyme catalyzes the second step in the common metabolic pathway to synthesize Thr and Met from Asp [H]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=373, Percent_Identity=23.5924932975871, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320362, Length=360, Percent_Identity=46.3888888888889, Blast_Score=296, Evalue=3e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000319
- InterPro:   IPR005676
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 38904; Mature: 38904

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKVGVLGATGNVGQRFMQMLENHPIFELEVLGASSRSAGKKYADACYWYQTEPIPEEYA
CEEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHEEEEECCCCCCHHHH
NKMVQTTDPTDKAYEDVDIVFSALPSDLAKKLEPEFAKEGKLVFSNASAMRMENDVPLMI
CCCEECCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHCCCEEEECCCCEEECCCCCEEE
PEVNYDHFEMLDIQRENRNYDGAIITNPNCSTICAVITLKPIMDKFGIDLVNITTMQAIS
ECCCCCCEEEEEEECCCCCCCCEEEECCCCHHEEHHHHHHHHHHHHCCEEEEEEHHHHHC
GAGYNGVPSMAIIDNLVPYIGSEEEKMQTESLKLLGAIDKENNKFTDANFKIGVSCNRVS
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHEEEEEECCCCEEECCCEEEEEEECEEE
VIDGHTESIFVKTTEEATPEEIKKVMDKFDPLKEYNLPTYAKPIVIREEMDRPQPRLDRD
EECCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHCCCCCCCCCEEEEHHCCCCCCCCCCC
AGNGMSISVGRIREDPVFGIKYTALEHNTIRGAAGASVLNAELYVKKYL
CCCCCEEEECCCCCCCCCEEEEEEEECCCCCCCCCCHHEEHEEEEEECC
>Mature Secondary Structure
MIKVGVLGATGNVGQRFMQMLENHPIFELEVLGASSRSAGKKYADACYWYQTEPIPEEYA
CEEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHEEEEECCCCCCHHHH
NKMVQTTDPTDKAYEDVDIVFSALPSDLAKKLEPEFAKEGKLVFSNASAMRMENDVPLMI
CCCEECCCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHCCCEEEECCCCEEECCCCCEEE
PEVNYDHFEMLDIQRENRNYDGAIITNPNCSTICAVITLKPIMDKFGIDLVNITTMQAIS
ECCCCCCEEEEEEECCCCCCCCEEEECCCCHHEEHHHHHHHHHHHHCCEEEEEEHHHHHC
GAGYNGVPSMAIIDNLVPYIGSEEEKMQTESLKLLGAIDKENNKFTDANFKIGVSCNRVS
CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHEEEEEECCCCEEECCCEEEEEEECEEE
VIDGHTESIFVKTTEEATPEEIKKVMDKFDPLKEYNLPTYAKPIVIREEMDRPQPRLDRD
EECCCCCEEEEEECCCCCHHHHHHHHHHCCCHHHCCCCCCCCCEEEEHHCCCCCCCCCCC
AGNGMSISVGRIREDPVFGIKYTALEHNTIRGAAGASVLNAELYVKKYL
CCCCCEEEECCCCCCCCCEEEEEEEECCCCCCCCCCHHEEHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]