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The map label for this gene is pfdA

Identifier: 150401786

GI number: 150401786

Start: 1425270

End: 1425704

Strand: Direct

Name: pfdA

Synonym: Maeo_1364

Alternate gene names: 150401786

Gene position: 1425270-1425704 (Clockwise)

Preceding gene: 150401784

Following gene: 150401787

Centisome position: 90.81

GC content: 34.71

Gene sequence:

>435_bases
ATGAATGAAGAATTACAACAACAATATTATCAGTTGGAAATGTATGGGCAACAAGTTCAAAAACTTCAAGAAGAACTTGA
AAAAATAGAGTTAATGAAAATGGAGCTCCTAAAATCAATAGATTCAATGGAAGGATTAAAAGATTCCGAGGATATATTAA
TACCTCTTGGAGGCGGCGCATTTATAAAGGCAAAAGCAATGGATACCAAAAAAGTAATTATGGGGGCCGGTGCAGATGTA
TTCCTTGAAAAAGATATTTCAGATGTTGTAGTAGATTTCAATAAATCTATTGAAGACTTGGATAAAGCTGGAAGTATGAT
TATTGCTAAAATAGAAGAAACTGCAAAAGTTGCAGAACAAATGCAGAAAGATTTGGAGGAAAAAGTTCAGGCCATGGAGG
GTCAAATGGGCGGAGCTCCAACACTTCAAATGTAA

Upstream 100 bases:

>100_bases
TTTTCTATACAATAATTTATAATTATTAATAATTACAAATAGGTATATATATGTTTGTATCCTATATAAATCAATAAAAA
TAATAATTATTGGTGAAAAT

Downstream 100 bases:

>100_bases
AAAATACATAAAATCGGAGATTTTGAATTTTCCACGCTGTGAAAAAATAGGATAAACTATATATACCATATATGATGATA
AGTATAACTATATTACTTAA

Product: prefoldin subunit alpha

Products: NA

Alternate protein names: GimC subunit alpha

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MNEELQQQYYQLEMYGQQVQKLQEELEKIELMKMELLKSIDSMEGLKDSEDILIPLGGGAFIKAKAMDTKKVIMGAGADV
FLEKDISDVVVDFNKSIEDLDKAGSMIIAKIEETAKVAEQMQKDLEEKVQAMEGQMGGAPTLQM

Sequences:

>Translated_144_residues
MNEELQQQYYQLEMYGQQVQKLQEELEKIELMKMELLKSIDSMEGLKDSEDILIPLGGGAFIKAKAMDTKKVIMGAGADV
FLEKDISDVVVDFNKSIEDLDKAGSMIIAKIEETAKVAEQMQKDLEEKVQAMEGQMGGAPTLQM
>Mature_144_residues
MNEELQQQYYQLEMYGQQVQKLQEELEKIELMKMELLKSIDSMEGLKDSEDILIPLGGGAFIKAKAMDTKKVIMGAGADV
FLEKDISDVVVDFNKSIEDLDKAGSMIIAKIEETAKVAEQMQKDLEEKVQAMEGQMGGAPTLQM

Specific function: Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding

COG id: COG1730

COG function: function code O; Predicted prefoldin, molecular chaperone implicated in de novo protein folding

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prefoldin alpha subunit family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PFDA_META3 (A6UWR8)

Other databases:

- EMBL:   CP000743
- RefSeq:   YP_001325552.1
- ProteinModelPortal:   A6UWR8
- SMR:   A6UWR8
- STRING:   A6UWR8
- GeneID:   5327172
- GenomeReviews:   CP000743_GR
- KEGG:   mae:Maeo_1364
- eggNOG:   arNOG13086
- HOGENOM:   HBG541032
- OMA:   EELQNQF
- ProtClustDB:   PRK14011
- BioCyc:   MAEO419665:MAEO_1364-MONOMER
- HAMAP:   MF_00308
- InterPro:   IPR011599
- InterPro:   IPR009053
- InterPro:   IPR004127
- TIGRFAMs:   TIGR00293

Pfam domain/function: PF02996 Prefoldin; SSF46579 Prefoldin

EC number: NA

Molecular weight: Translated: 16110; Mature: 16110

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
8.3 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
8.3 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEELQQQYYQLEMYGQQVQKLQEELEKIELMKMELLKSIDSMEGLKDSEDILIPLGGGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCC
FIKAKAMDTKKVIMGAGADVFLEKDISDVVVDFNKSIEDLDKAGSMIIAKIEETAKVAEQ
EEEEECCCHHHHHHCCCCCCEECCCHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHH
MQKDLEEKVQAMEGQMGGAPTLQM
HHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNEELQQQYYQLEMYGQQVQKLQEELEKIELMKMELLKSIDSMEGLKDSEDILIPLGGGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCC
FIKAKAMDTKKVIMGAGADVFLEKDISDVVVDFNKSIEDLDKAGSMIIAKIEETAKVAEQ
EEEEECCCHHHHHHCCCCCCEECCCHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHH
MQKDLEEKVQAMEGQMGGAPTLQM
HHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA